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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rsp</journal-id><journal-title-group><journal-title xml:lang="ru">Научно-практическая ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Rheumatology Science and Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-4484</issn><issn pub-type="epub">1995-4492</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1995-4484-2009-1156</article-id><article-id custom-type="elpub" pub-id-type="custom">rsp-1070</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Поражение легких при болезни Бехчета</article-title><trans-title-group xml:lang="en"><trans-title>Lungs damage in Behçet’s disease</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Голоева</surname><given-names>Р. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Goloeva</surname><given-names>R G</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алекберова</surname><given-names>Земфира Садуллаевна</given-names></name><name name-style="western" xml:lang="en"><surname>Alekberova</surname><given-names>Z S</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Lapinaa</surname><given-names>T V</given-names></name><name name-style="western" xml:lang="en"><surname>Lapinaa</surname><given-names>T V</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib></contrib-group><pub-date pub-type="collection"><year>2009</year></pub-date><pub-date pub-type="epub"><day>15</day><month>08</month><year>2009</year></pub-date><volume>47</volume><issue>4</issue><issue-title>№4 (2009)</issue-title><fpage>90</fpage><lpage>96</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Голоева Р.Г., Алекберова З.С., Lapinaa T.V., 2009</copyright-statement><copyright-year>2009</copyright-year><copyright-holder xml:lang="ru">Голоева Р.Г., Алекберова З.С., Lapinaa T.V.</copyright-holder><copyright-holder xml:lang="en">Goloeva R.G., Alekberova Z.S., Lapinaa T.V.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://rsp.mediar-press.net/rsp/article/view/1070">https://rsp.mediar-press.net/rsp/article/view/1070</self-uri><abstract><p>Болезнь Бехчета (ББ) — системный васкулит неустановленной этиологии, характеризующийся язвенным поражением слизистой полости рта и половых органов, глаз и кожи. Другие органы (нервная система, легкие, суставы, желудочно-кишечный тракт) поражаются нечасто.Особенностью этого васкулита является поражение сосудов всех размеров и типов. Представлены обзор основных легочных проявлений ББ (аневризмы легочных артерий, артериальные и венозные тромбозы, паренхиматозное поражение легких) и описание собственного наблюдения больного ББ c множественными легочными аневризмами.</p></abstract><trans-abstract xml:lang="en"><p>Behçet’s disease (BD) is a systemic vasculitis of unknown origin characterized by ulcerous damage of oral and genital mucosa as well as eyes and skin. Other organs (nervous system, lungs, joints, gastro-intestinal tract) are rarely involved. Damage of vessels of all sizes and types is a feature of this vasculitis. Review of main lung BD manifestations (pulmonary artery aneurisms, arterial and venous thrombosis, parenchymatous lung damage) and own description of a pt with BD with multiple pulmonary aneurisms are presented.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>Болезнь Бехчета</kwd><kwd>поражение легких</kwd><kwd>аневризмы легочных артерий</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Behçet’s disease</kwd><kwd>pulmonary damage</kwd><kwd>pulmonary artery aneurisms</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">&lt;div&gt;&lt;p&gt;Алекберова З. С. Болезнь Бехчета, М., 2007, 90с.&lt;/p&gt;&lt;p&gt;Neuman I. Die Aphten am weiblichen genitale. Wien. Klin. Rundsch., 1895, 9, 289-90.&lt;/p&gt;&lt;p&gt;Blüthe L. Zur Kenntnis des recidivereden Hypopyons. Inaugural Thesis, 1908, Heidelberg.&lt;/p&gt;&lt;p&gt;Adamantiades B. Sur un cas d’iritis a hypopyon récidivant. Ann. Ocul. (Paris), 1931, 168, 271-8.&lt;/p&gt;&lt;p&gt;Behçet H. Uber rezidivierende aphthose, durch ein virus verursachte Geschwure am Mund, am Auge und an den Genitalien. Dermatol. Woschenschr, 1937, 105, 1152-57.&lt;/p&gt;&lt;p&gt;International Study Group For Behcet‘s Disease: Criteria for diagnosis of Behcet’s disease. Lancet, 1990, 335, 1078-80.&lt;/p&gt;&lt;p&gt;Sulheim O., Dalgaard J., Andersen R. Behcet’s syndrome. Acta Pathol. Microbiоl. Scand., 1959, 45, 145-59.&lt;/p&gt;&lt;p&gt;Uzun O, Akpolat T, Erkan L. Pulmonary vasculitis in Behcet disease: a cumulative analysis. Chest, 2005, 127(6), 2243-53.&lt;/p&gt;&lt;p&gt;Berkan O., Ozturkcan S., Dogan K. et al. Pulmonary arterial aneurysm in Behcet‘s disease. J. Eur. Acad. Dermatol. Venereol., 1999, 13, 140-1&lt;/p&gt;&lt;p&gt;Raz I., Okon E., Chajek-Shaul T. Pulmonary manifestations in Behcet’s syndrome. Chest, 1989, 95, 585-9.&lt;/p&gt;&lt;p&gt;Aktogu S., Erer O., Urpek G. et al. Multiple pulmonary arterial aneurysms in Behcet‘s disease: clinical and radiologic remission after cyclophosphamide and corticosteroid therapy. Respiration, 2002, 69, 178-81.&lt;/p&gt;&lt;p&gt;Erkan F. Pulmonary involvement in Behçet disease. Curr. Opin. Pulm. Med., 1999, 5, 314-8.&lt;/p&gt;&lt;p&gt;Unlu M., Akincioglu C., Yamac K. et al. Pulmonary involvement in Behcet’s disease: evaluation of 123&lt;/p&gt;&lt;p&gt;I-MIBG retention. Nucl. Med. Commun., 2001, 22, 1083-8.&lt;/p&gt;&lt;p&gt;Zouboulis C., Kotter I., Djawari D. et al. Epidemiological features of Adamantiades-Behcet’s disease in Germany and in Europe. Yonsei Med. J., 1997, 38, 411-22.&lt;/p&gt;&lt;p&gt;Cohle S., Colby T. Fatal hemoptysis from Behcet’s disease in a child. Cardiovasc Pathol., 2002, 1, 296-9.&lt;/p&gt;&lt;p&gt;Filiz A., Dikensoy O. Lethal aneurysm formation of pulmonary arteries in a woman with Behcet‘s disease. Rheumatology, 2000, 39, 222-4.&lt;/p&gt;&lt;p&gt;Hamuryudan V., Yurdakul S., Moral F. et al Pulmonary arterial aneurysms in Behcet’s syndrome: a report of 24 cases. Br. J. Rheumatol., 1994, 33, 48-51.&lt;/p&gt;&lt;p&gt;Santana A., Antunes T., Barros J. et al. Pulmonary involvement in Behcet’s disease: a positive singlecenter experience with the use of immunosuppressive therapy J. Bras. Pneumol., 2008, 34(6), 362-6.&lt;/p&gt;&lt;p&gt;Seyahi E., Melikoglu M., Akman C. et al. Pulmonary vascular involvement in Behcet’s syndrome. Clin. Exp. Rheumat., 2006, 24 (42), 22.&lt;/p&gt;&lt;p&gt;Basak M., Gül S., Yazgan Y. et al. A case of rapidly progressive pulmonary aneurysm as a rare complication of Behcet’s syndrome. Angiology, 1998, 49, 403-8.&lt;/p&gt;&lt;p&gt;Bowman S., Honey M. Pulmonary arterial occlusions and aneurysms: a forme fruste of Behcet’s or Hughes-Stovin syndrome. Br. Heart J., 1990, 63, 66-8.&lt;/p&gt;&lt;p&gt;Gibson R., Morgan S., Krausz T. et al. Pulmonary artery aneurysms in Behcet’s disease. Br. J. Radiol., 1985, 58, 79-82.&lt;/p&gt;&lt;p&gt;Gokcora N., Ilgin N., Isik S. et al. Behcet‘s disease: aggressive pulmonary involvement. Int. J. Dermatol., 1994, 33, 131-2.&lt;/p&gt;&lt;p&gt;Saba D., Saricaolu H., Bayram A. et al. Arterial lesions in Behcet’s disease. VASA, 2003, 32, 75-81.&lt;/p&gt;&lt;p&gt;Sakane T., Takeno M., Suzuki N. et al. Behcet’s disease. N. Engl. J. Med., 1999, 341, 1284-91.&lt;/p&gt;&lt;p&gt;Ahonen A., Stenius-Aarniala B., Viljanen B. et al. Obstructive lung disease in Behcet’s syndrome. Scand. J. Respir. Dis., 1978, 59, 44-50.&lt;/p&gt;&lt;p&gt;Fairly C., Wilson J., Barraclough D. Pulmonary involvement in Behcet’s syndrome. Chest, 1989, 96, 1428-9.&lt;/p&gt;&lt;p&gt;Gul A., Yilmazbayhan D., Buyukbabani N. et al. Organizing pneumonia associated with pulmonary artery aneurysms in Behcet’s disease. Rheumatology, 1999, 38, 1285-9&lt;/p&gt;&lt;p&gt;Petty T., Scoggin, C., Good J. Recurrent pneumonia in Behcet’s syndrome: roentgenographic documentation during 13 years. JAMA, 1977, 238, 2529-30.&lt;/p&gt;&lt;p&gt;Abadolu O., Osma E., Uçan E. et al. Behcet’s disease with pulmonary involvement, superior vena cava syndrome, chloptysis and chlous ascites. Respir. Med., 1996, 90, 429-31.&lt;/p&gt;&lt;p&gt;Kroger K, Ansasy M., Rudofsky G. Postoperative thrombosis of the superior caval vein in a patient with primary asymptomatic Behçet’s disease. Angiology, 1997, 48, 649-53.&lt;/p&gt;&lt;p&gt;Plotkin G., Part I. Miscellaneous clinical manifestations, Cardiac, vascular, renal and pulmonary features in Behet’s disease. In: Plotkin G., Calabro J., O’Duffy J. et al. Behet’s disease: A contemporary synopsis. New York: Futura, 1988, 203–8.&lt;/p&gt;&lt;p&gt;Tuzun H, Besirli K, Sayin A, et al. Management of aneurysms in Behcet’s syndrome: an analysis of 24 patients. Surgery, 1997, 121, 150-6.&lt;/p&gt;&lt;p&gt;Greene R., Saleh A., Taylor A. et al. 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AJR, 1995, 76, 155-7.&lt;/p&gt;&lt;/div&gt;&lt;br /&gt;</mixed-citation><mixed-citation xml:lang="en">&lt;div&gt;&lt;p&gt;Алекберова З. С. Болезнь Бехчета, М., 2007, 90с.&lt;/p&gt;&lt;p&gt;Neuman I. Die Aphten am weiblichen genitale. Wien. Klin. Rundsch., 1895, 9, 289-90.&lt;/p&gt;&lt;p&gt;Blüthe L. Zur Kenntnis des recidivereden Hypopyons. Inaugural Thesis, 1908, Heidelberg.&lt;/p&gt;&lt;p&gt;Adamantiades B. Sur un cas d’iritis a hypopyon récidivant. Ann. Ocul. (Paris), 1931, 168, 271-8.&lt;/p&gt;&lt;p&gt;Behçet H. Uber rezidivierende aphthose, durch ein virus verursachte Geschwure am Mund, am Auge und an den Genitalien. Dermatol. Woschenschr, 1937, 105, 1152-57.&lt;/p&gt;&lt;p&gt;International Study Group For Behcet‘s Disease: Criteria for diagnosis of Behcet’s disease. Lancet, 1990, 335, 1078-80.&lt;/p&gt;&lt;p&gt;Sulheim O., Dalgaard J., Andersen R. Behcet’s syndrome. Acta Pathol. Microbiоl. Scand., 1959, 45, 145-59.&lt;/p&gt;&lt;p&gt;Uzun O, Akpolat T, Erkan L. Pulmonary vasculitis in Behcet disease: a cumulative analysis. Chest, 2005, 127(6), 2243-53.&lt;/p&gt;&lt;p&gt;Berkan O., Ozturkcan S., Dogan K. et al. Pulmonary arterial aneurysm in Behcet‘s disease. J. Eur. Acad. Dermatol. Venereol., 1999, 13, 140-1&lt;/p&gt;&lt;p&gt;Raz I., Okon E., Chajek-Shaul T. Pulmonary manifestations in Behcet’s syndrome. Chest, 1989, 95, 585-9.&lt;/p&gt;&lt;p&gt;Aktogu S., Erer O., Urpek G. et al. Multiple pulmonary arterial aneurysms in Behcet‘s disease: clinical and radiologic remission after cyclophosphamide and corticosteroid therapy. Respiration, 2002, 69, 178-81.&lt;/p&gt;&lt;p&gt;Erkan F. Pulmonary involvement in Behçet disease. Curr. Opin. Pulm. Med., 1999, 5, 314-8.&lt;/p&gt;&lt;p&gt;Unlu M., Akincioglu C., Yamac K. et al. Pulmonary involvement in Behcet’s disease: evaluation of 123&lt;/p&gt;&lt;p&gt;I-MIBG retention. Nucl. Med. Commun., 2001, 22, 1083-8.&lt;/p&gt;&lt;p&gt;Zouboulis C., Kotter I., Djawari D. et al. Epidemiological features of Adamantiades-Behcet’s disease in Germany and in Europe. Yonsei Med. J., 1997, 38, 411-22.&lt;/p&gt;&lt;p&gt;Cohle S., Colby T. Fatal hemoptysis from Behcet’s disease in a child. Cardiovasc Pathol., 2002, 1, 296-9.&lt;/p&gt;&lt;p&gt;Filiz A., Dikensoy O. Lethal aneurysm formation of pulmonary arteries in a woman with Behcet‘s disease. Rheumatology, 2000, 39, 222-4.&lt;/p&gt;&lt;p&gt;Hamuryudan V., Yurdakul S., Moral F. et al Pulmonary arterial aneurysms in Behcet’s syndrome: a report of 24 cases. Br. J. Rheumatol., 1994, 33, 48-51.&lt;/p&gt;&lt;p&gt;Santana A., Antunes T., Barros J. et al. Pulmonary involvement in Behcet’s disease: a positive singlecenter experience with the use of immunosuppressive therapy J. Bras. Pneumol., 2008, 34(6), 362-6.&lt;/p&gt;&lt;p&gt;Seyahi E., Melikoglu M., Akman C. et al. Pulmonary vascular involvement in Behcet’s syndrome. Clin. Exp. Rheumat., 2006, 24 (42), 22.&lt;/p&gt;&lt;p&gt;Basak M., Gül S., Yazgan Y. et al. A case of rapidly progressive pulmonary aneurysm as a rare complication of Behcet’s syndrome. Angiology, 1998, 49, 403-8.&lt;/p&gt;&lt;p&gt;Bowman S., Honey M. Pulmonary arterial occlusions and aneurysms: a forme fruste of Behcet’s or Hughes-Stovin syndrome. Br. Heart J., 1990, 63, 66-8.&lt;/p&gt;&lt;p&gt;Gibson R., Morgan S., Krausz T. et al. Pulmonary artery aneurysms in Behcet’s disease. Br. J. Radiol., 1985, 58, 79-82.&lt;/p&gt;&lt;p&gt;Gokcora N., Ilgin N., Isik S. et al. Behcet‘s disease: aggressive pulmonary involvement. Int. J. Dermatol., 1994, 33, 131-2.&lt;/p&gt;&lt;p&gt;Saba D., Saricaolu H., Bayram A. et al. Arterial lesions in Behcet’s disease. VASA, 2003, 32, 75-81.&lt;/p&gt;&lt;p&gt;Sakane T., Takeno M., Suzuki N. et al. Behcet’s disease. N. Engl. J. Med., 1999, 341, 1284-91.&lt;/p&gt;&lt;p&gt;Ahonen A., Stenius-Aarniala B., Viljanen B. et al. Obstructive lung disease in Behcet’s syndrome. Scand. J. Respir. 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