rspНаучно-практическая ревматологияRheumatology Science and Practice1995-44841995-4492IMA-PRESS, LLC10.14412/1995-4484-2014-247-250rsp-1934Research ArticleПЕРЕДОВАЯLEADING ARTICLEПерспективные направления терапии остеоартрозаPERSPECTIVE DIRECTIONS OF OSTEOARTHRITIS THERAPYАлексееваЛ. И.AlekseevaL. I.alekseeva@irramn.ruЗайцеваЕ. М.ZaitsevaE. M.ФГБУ «Научно- исследовательский институт ревматологии им. В.А. Насоновой» РАН, МоскваРоссияNasonova Research Institute of Rheumatology, Moscow, RussiaRussian Federation201420062014523№3 (2014)247250Copyright © Алексеева Л.И., Зайцева Е.М., 20142014Алексеева Л.И., Зайцева Е.М.Alekseeva L.I., Zaitseva E.M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://rsp.mediar-press.net/rsp/article/view/1934

В статье обсуждаются новые механизмы патогенеза остеоартроза (ОА). Особое внимание уделено роли про- цессов ремоделирования субхондральной кости, медиаторам воспаления, костным морфогенным белкам и др. Эти данные могут иметь важное значение для разработки новых подходов к лечению ОА.

The paper discusses the new mechanisms of osteoarthritis (OA) pathogenesis. Particular emphasis is placed on the role of subchondral bone remodeling, inflammatory mediators, bone morphogenetic proteins, etc. These data may be of great importance for elaborating new approaches to OA treatment.

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The authors declare that there are no conflicts of interest present.