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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rsp</journal-id><journal-title-group><journal-title xml:lang="ru">Научно-практическая ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Rheumatology Science and Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-4484</issn><issn pub-type="epub">1995-4492</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1995-4484-2014-366-375</article-id><article-id custom-type="elpub" pub-id-type="custom">rsp-1956</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>МЕЖДУНАРОДНЫЕ И РОССИЙСКИЕ РЕКОМЕНДАЦИИ ПО ЛЕЧЕНИЮ РЕВМАТИЧЕСКИХ ЗАБОЛЕВАНИЙ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>INTERNATIONAL AND RUSSIAN GUIDELINES FOR THE TREATMENT OF RHEUMATIC DISEASES</subject></subj-group></article-categories><title-group><article-title>Периоперационное ведение больных ревматоидным артритом</article-title><trans-title-group xml:lang="en"><trans-title>PERIOPERATIVE MANAGEMENT OF PATIENTS WITH RHEUMATOID ARTHRITIS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Амирджанова</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Amirdzhanova</surname><given-names>V. N.</given-names></name></name-alternatives><email xlink:type="simple">amirver@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Макаров</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Makarov</surname><given-names>M. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бялик</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Byalik</surname><given-names>E. I.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Макаров</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Makarov</surname><given-names>S. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Липина</surname><given-names>М. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Lipina</surname><given-names>M. M.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ Научно-исследовательский институт ревматологии им. В.А. Насоновой, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.A. Nasonova Research Institute of Rheumatology, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>02</day><month>09</month><year>2014</year></pub-date><volume>52</volume><issue>4</issue><fpage>366</fpage><lpage>375</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Амирджанова В.Н., Макаров М.А., Бялик Е.И., Макаров С.А., Липина М.М., 2014</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="ru">Амирджанова В.Н., Макаров М.А., Бялик Е.И., Макаров С.А., Липина М.М.</copyright-holder><copyright-holder xml:lang="en">Amirdzhanova V.N., Makarov M.A., Byalik E.I., Makarov S.A., Lipina M.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://rsp.mediar-press.net/rsp/article/view/1956">https://rsp.mediar-press.net/rsp/article/view/1956</self-uri><abstract><p>В статье рассматриваются рекомендации по совместному ведению больных ревматоидным артритом, нуждающихся в эндопротезировании крупных суставов нижних конечностей, ревматологами и травматологами-ортопедами. В связи с отсутствием общепринятых стандартов и рекомендаций по периоперативному ведению больных с ревматическими заболеваниями, принятых международными ревматологическими ассоциациями, в статье обобщен собственный опыт ведения пациентов с учетом международных подходов и рекомендаций разных стран. Обсуждаются подходы к оценке и снижению рисков кардиоваскулярной патологии, профилактики инфекционных осложнений, кровотечений, тромбозов глубоких вен нижних конечностей, особенности ведения больных с остеопорозом. Подробно представлен опыт ведения больных, получающих антиревматическую терапию нестероидными противовоспалительными препаратами, базисными противовоспалительными препаратами: метотрексатом, лефлуномидом, сульфасалазином, гидроксихлорохином. Даются рекомендации по ведению больных, получающих глюкокортикоиды и генно-инженерные биологические препараты (ингибиторы фактора некроза опухоли α, анти-В-клеточную терапию и ингибиторы рецепторов интерлейкина 6), в предоперационном и послеоперационном периоде.</p></abstract><trans-abstract xml:lang="en"><p>The paper considers the joint management of rheumatoid arthritis patients needing endoprosthetic replacement of the large joints of the lower extremities by rheumatologists and orthopedic traumatologists.Due to the fact that there are no conventional standards or guidelines for the perioperative management of patients with rheumatic diseases, adopted by international rheumatology associations, the authors generalize their experience in managing the patients in terms of international approaches and guidelines from different countries. The medical assessment and reduction of cardiovascular risks, the prevention of infectious complications, hemorrhages, and lower extremity deep vein thrombosis, and the specific features of management of patients with osteoporosis are under consideration. The authors' experience in managing the patients receiving antirheumatic therapy with nonsteroidal antiinflammatory and disease-modifying antirheumatic drugs, such as methotrexate, leflunomide, sulfasalazine, and hydroxychloroquine, is detailed. Recommendations for managing patients taking glucocorticoids and biologic agents (tumor necrosis factor-α inhibitors, anti-B-cell therapy, and interleukin-6 receptor inhibitors) in the preoperative andpostoperative periods are given.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ревматоидный артрит</kwd><kwd>эндопротезирование суставов</kwd><kwd>базисные противовспалительные пре- параты</kwd><kwd>генно-инженерные биологические препараты</kwd></kwd-group><kwd-group xml:lang="en"><kwd>rheumatoid arthritis</kwd><kwd>endoprosthetic joint replacement</kwd><kwd>disease-modifying antirheumatic drugs</kwd><kwd>genetically engineered biological agents</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Насонов ЕЛ, редактор. Ревматология. Клинические рекомендации. Москва: ГЭОТАР-Медиа; 2010. 288 с. [Nasonov EL, editor. Revmatologiya. Klinicheskie rekomendatsii [Rheumatology. 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