rspНаучно-практическая ревматологияRheumatology Science and Practice1995-44841995-4492IMA-PRESS, LLC10.14412/1995-4484-2014-553-561rsp-1991Research ArticleОБЗОРREVIEWФакторы риска прогрессирования остеоартроза коленных суставовRISK FACTORS OF THE KNEE OSTEOARTHRITIS PROGRESSIONКашевароваН. Г.KashevarovaN. G.nat-kash@yandex.ruАлексееваЛ. И.AlekseevaL. I.ФГБНУ Научно-исследовательский институт ревматологии им. В.А. Насоновой, Москва, РоссияРоссияV.A. Nasonova Research Institute of Rheumatology, Moscow, RussiaRussian Federation201407102014525553561Copyright © Кашеварова Н.Г., Алексеева Л.И., 20142014Кашеварова Н.Г., Алексеева Л.И.Kashevarova N.G., Alekseeva L.I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://rsp.mediar-press.net/rsp/article/view/1991

В обзоре освещена проблема прогрессирования остеоартроза коленных суставов. Показано, что наиболеезначимыми предикторами прогрессирования заболевания являются: женский пол, интенсивная боль в коленных суставах, наличие синовита, деформация суставов, повышенный индекс массы тела, травмы в анамнезе, высокие значения минеральной плотности кости осевого скелета и субхондральных отделов бедренной и большеберцовой костей, наличие отека костного мозга. Несмотря на множество проведенных исследований по выявлению факторов риска прогрессирования гонартроза, результаты остаются противоречивыми и требуют дальнейшего его исследования.

The present review is devoted to the problem of progression of the knee osteoarthritis. It has been shown that the most important predictors of the disease progression are female gender, strong knee pain, synovitis,deformation of joints, high body mass index, previous traumas, high bone mineral density of the axial skeleton and subchondral parts of femur and tibia, bone marrow edema. Despite numerous studies conducted in order to reveal risk factors of knee osteoarthritis, results remain controversial and require further investigation.

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The authors declare that there are no conflicts of interest present.