rspНаучно-практическая ревматологияRheumatology Science and Practice1995-44841995-4492IMA-PRESS, LLC10.14412/1995-4484-2014-562-571rsp-1993Research ArticleОБЗОРREVIEWФакторы риска развития остеопороза у больных ревматоидным артритомRISK FACTORS FOR OSTEOPOROSIS IN PATIENTS WITH RHEUMATOID ARTHRITISТаскинаЕ. А.TaskinaE. A.braell@mail.ruАлексееваЛ. И.AlekseevaL. I.ФГБНУ Научно-исследовательский институт ревматологии им. В.А. Насоновой, Москва, РоссияРоссияV.A. Nasonova Research Institute of Rheumatology, Moscow, RussiaRussian Federation201407102014525562571Copyright © Таскина Е.А., Алексеева Л.И., 20142014Таскина Е.А., Алексеева Л.И.Taskina E.A., Alekseeva L.I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://rsp.mediar-press.net/rsp/article/view/1993

Данный обзор посвящен рассмотрению факторов риска (ФР) развития остеопороза (ОП) у больных ревматоидным артритом (РА) – как связанных с основным заболеванием, так и не связанных. Предполагается, что наиболее значимыми предикторами снижения минеральной плотности кости являются тяжелое течение РА, выраженная функциональная недостаточность по HAQ, терапия глюкокортикоидами, пожилой возраст, недостаточная масса тела или низкий индекс массы тела, наличие менопаузы. Однако, несмотря на большое количество проведенных исследований, результаты по ФР ОП остаются противоречивыми и требуют дальнейшего изучения.

The present review is devoted to the risk factors of osteoporosis progression in patients with rheumatoid arthritis (RA), both relevant and irrelevant to the main disease. It is assumed that the most important predictors of the bone mineral density decrease is severe course of RA, significant functional disability (according to HAQ), glucocorticoid therapy, elderly age, low body mass index and menopause. However, despite the vast amount of studies, results on the risk factors of osteoporosis remain ambiguous and require further investigation.

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The authors declare that there are no conflicts of interest present.