rspНаучно-практическая ревматологияRheumatology Science and Practice1995-44841995-4492IMA-PRESS, LLC10.14412/1995-4484-2014-660-668rsp-2012Research ArticleПРОГРЕСС В РЕВМАТОЛОГИИ В XXI ВЕКЕPROGRESS IN RHEUMATOLOGY IN THE XXI CENTURYВакцинация в ревматологии: современные аспектыVACCINATION IN RHEUMATOLOGY: CURRENT ASPECTSБеловБ. С.BelovB. S.

руководитель лаборатории изучения роли инфекции при ревматических заболеваниях ФГБНУ им. В.А. Насоновой, докт. мед. наук

belovbor@yandex.ruНаумцеваМ. С.NaumtsevaM. S.

аспирант ФГБНУ им. В.А. Насоновой

ТарасоваГ. М.TarasovaG. M.

старший сотрудник лаборатории изучения роли инфекции при ревматических заболеваниях ФГБНУ им. В.А. Насоновой, канд. мед. наук

ПолянскаяМ. В.PolyanskayaM. V.

научный сотрудник лаборатории изучения роли инфекции при ревматических заболеваниях ФГБНУ им. В.А. Насоновой, канд. мед. наук

ФГБНУ Научно-исследовательский институт ревматологии им. В.А. Насоновой, Москва, Россия 115522, Москва, Каширское шоссе, 34АРоссияV.A. Nasonova Research Institute of Rheumatology, Moscow, Russia; 34A, Kashirskoe Shosse, Moscow 115522Russian Federation201417122014526660668Copyright © Белов Б.С., Наумцева М.С., Тарасова Г.М., Полянская М.В., 20142014Белов Б.С., Наумцева М.С., Тарасова Г.М., Полянская М.В.Belov B.S., Naumtseva M.S., Tarasova G.M., Polyanskaya M.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://rsp.mediar-press.net/rsp/article/view/2012

Инфекционные заболевания по-прежнему остаются серьезной социальной и медицинской проблемой. В ревматологии значимость коморбидных инфекций за последнее время существенно увеличилась, особенно в связи с внедрением в клиническую практику генно-инженерных биологических препаратов. Одним из путей решения указанной проблемы является изучение и активное применение различных вакцин. В настоящем обзоре рассмотрены вопросы, касающиеся применения вакцин против гриппа, инфекций, обусловленных пневмококками, вирусами герпеса, папилломы человека и гепатита В у ревматологических больных. Обсуждаются безопасность и иммуногенность вакцинации, связанной с предупреждением инфекций дыхательных путей как наиболее частой причины неблагоприятного исхода при ревматических заболеваниях. Обозначены основные направления будущих исследований по рассматриваемой проблеме.

Infectious diseases still remain a serious social and medical problem. The importance of comorbid infections in rheumatology has increased substantially in recent years, particularly due to the clinical introduction of biologicals. The investigation and active use of different vaccines are one of the ways to solve the above problem. This review considers the issues concerning the use of vaccines against influenza, infections caused by pneumococci, herpesviruses, human papillomavirus, and hepatitis B virus in rheumatology patients. It discusses the safety and immunogenicity of vaccination associated with the prevention of airway infections as the most common cause of a poor outcome in rheumatic diseases. The main areas of future investigations in the problem under consideration are defined.

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The authors declare that there are no conflicts of interest present.