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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rsp</journal-id><journal-title-group><journal-title xml:lang="ru">Научно-практическая ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Rheumatology Science and Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-4484</issn><issn pub-type="epub">1995-4492</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1995-4484-2014-689-696</article-id><article-id custom-type="elpub" pub-id-type="custom">rsp-2016</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ИНФОРМАЦИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>INFORMATION</subject></subj-group></article-categories><title-group><article-title>Европейский конгресс ревматологов, (Париж, 11–14 июня 2014 г.) – проблемы ревматоидного артрита</article-title><trans-title-group xml:lang="en"><trans-title>THE EUROPEAN CONGRESS OF RHEUMATOLOGY (PARIS, 11–14 JUNE 2014): PROBLEMS OF RHEUMATOID ARTHRITIS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Авдеева</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Avdeeva</surname><given-names>A. S.</given-names></name></name-alternatives><email xlink:type="simple">9056249400@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каратеев</surname><given-names>Д. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Karateev</surname><given-names>D. E.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Денисов</surname><given-names>Л. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Denisov</surname><given-names>L. N.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Насонов</surname><given-names>Е. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Nasonov</surname><given-names>E. L.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ФГБНУ Научно-исследовательский институт ревматологии им. В.А. Насоновой, Москва, Россия 115522, Москва, Каширское шоссе, 34А<country>Россия</country></aff><aff xml:lang="en">V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia 34A, Kashirskoe Shosse, Moscow 115522<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>17</day><month>12</month><year>2014</year></pub-date><volume>52</volume><issue>6</issue><fpage>689</fpage><lpage>696</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Авдеева А.С., Каратеев Д.Е., Денисов Л.Н., Насонов Е.Л., 2014</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="ru">Авдеева А.С., Каратеев Д.Е., Денисов Л.Н., Насонов Е.Л.</copyright-holder><copyright-holder xml:lang="en">Avdeeva A.S., Karateev D.E., Denisov L.N., Nasonov E.L.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://rsp.mediar-press.net/rsp/article/view/2016">https://rsp.mediar-press.net/rsp/article/view/2016</self-uri><abstract><p>В июне 2014 г. в Париже прошел 15-й ежегодный Европейский конгресс ревматологов. Программа конгресса была чрезвычайно многообразна, она включала обсуждение новых данных, касающихся диагностики и лечения наиболее распространенных ревматических заболеваний, проблем их этиологии и патогенеза, персонифицированной терапии и многое другое. Одно из центральных мест на конгрессе занимали вопросы раннего ревматоидного артрита (РА). Ряд работ касался эффективности и безопасности применения различных схем терапии РА в дебюте заболевания, вопросам отмены терапии генно-инженерными биологическими препаратами при достижении ремиссии, а также сохранение безлекарственной ремиссии РА. На конгрессе обсуждались новые результаты исследования tREACH, в котором сравнивались три схемы лечения пациентов с ранним воспалительным артритом: комбинированная терапия метотрексатом (МТ), сульфасалазином и гидроксихлорохином в сочетании с внутримышечным введением глюкокортикоидов (ГК), комбинированной терапии этими препаратами и перорально принимаемыми ГК и монотерапии МТ с пероральным приемом ГК Большое количество докладов касалось применения ингибиторов фактора некроза опухоли α, оценке их иммуногенности, а также анализу причин отмены терапии и нежелательным реакциям, развивающимся на фоне лечения. Обсуждались некоторые аспекты терапии традиционными базисными противовоспалительными препаратами. Ряд докладов касался применения новых лабораторных биомаркеров РА. Таким образом, на конгрессе было представлено достаточно много новых данных, которые позволят оптимизировать терапию такого распространенного ревматического заболевания, как РА.</p></abstract><trans-abstract xml:lang="en"><p>The 15th annual European Congress of Rheumatology took place in Paris in June 2014. Its program was extremely diverse and included a discussion of new data pertinent to the diagnosis and treatment of the most common rheumatic diseases and problems of their etiology and pathogenesis, personified therapy, and many others. The Congress focused on the problems of early rheumatoid arthritis (RA). A number of papers concerned the efficiency and safety of different therapy regimens for RA at its onset, the discontinuation of biological therapy after achievement of remission, and the maintenance of drug-free RA remission. The Congress discussed new results of the tREACH trial comparing three treatment regimens for early inflammatory arthritis: combined therapy with methotrexate (MT), sulfasalazine, and hydroxychloroquine in conjunction with intramuscular glucocorticoids (GC); combined therapy with these drugs in conjunction with oral GC; and MT monotherapy with oral GC. A large number of reports dealt with the use of tumor necrosis factor-α inhibitors, the evaluation of their immunogenicity, and theanalysis of reasons for therapy discontinuation and adverse reactions. Some aspects of therapy with disease-difying antirheumatic drugs were discussed. A number of reports concerned the application of novel laboratory biomarkers for RA.Thus, sufficiently many new data that will be able to optimize therapy for common rheumatic disease, such as RA, were presented at the Congress.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>15-й Европейский конгресс ревматологов</kwd><kwd>ревматоидный артрит</kwd><kwd>генно-инженерные биологические препараты</kwd><kwd>ингибиторы фактора некроза опухоли α.</kwd></kwd-group><kwd-group xml:lang="en"><kwd>15th European Congress of Rheumatology</kwd><kwd>rheumatoid arthritis</kwd><kwd>biological agents</kwd><kwd>tumor necrosis factor-α inhibitors</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Van Nies JA, Gaujoux-Viala C, Tsonaka R, et al. When does the therapeutic window of opportunity in rheumatoid arthritis close? A study in two early RA cohorts. Ann Rheum Dis. 2014;73(Suppl 2). 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