<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rsp</journal-id><journal-title-group><journal-title xml:lang="ru">Научно-практическая ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Rheumatology Science and Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-4484</issn><issn pub-type="epub">1995-4492</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1995-4484-2015-289-298</article-id><article-id custom-type="elpub" pub-id-type="custom">rsp-2092</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПРОГРАММА НЕПРЕРЫВНОГО ПОСЛЕДИПЛОМНОГО ОБРАЗОВАНИЯ ВРАЧЕЙ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>POSTGRADUATE PROGRAM OF CONTINUING MEDICAL EDUCATION</subject></subj-group></article-categories><title-group><article-title>Инфекционный эндокардит в практике ревматолога: вопросы клинической картины и диагностики</article-title><trans-title-group xml:lang="en"><trans-title>INFECTIVE ENDOCARDITIS IN A RHEUMATOLOGIST’S PRACTICE: ISSUES OF ITS CLINICAL PRESENTATION AND DIAGNOSIS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белов</surname><given-names>Б. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Belov</surname><given-names>B. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>руководитель лаборатории изучения роли инфекции при ревматических заболеваниях ФГБНУ НИИР им. В.А. Насоновой, докт. мед. наук</p></bio><email xlink:type="simple">belovbor@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тарасова</surname><given-names>Г. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Tarasova</surname><given-names>G. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>старший научный сотрудник лаборатории изучения роли инфекции при ревматических заболеваниях ФГБНУ НИИР им. В.А. Насоновой, канд. мед. наук</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ Научно- исследовательский институт ревматологии им. В.А. Насоновой, Москва, Россия 115522 Москва, Каширское шоссе, 34А</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia; 34A, Kashirskoe Shosse, Moscow 115522</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>09</day><month>09</month><year>2015</year></pub-date><volume>53</volume><issue>3</issue><fpage>289</fpage><lpage>298</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Белов Б.С., Тарасова Г.М., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Белов Б.С., Тарасова Г.М.</copyright-holder><copyright-holder xml:lang="en">Belov B.S., Tarasova G.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://rsp.mediar-press.net/rsp/article/view/2092">https://rsp.mediar-press.net/rsp/article/view/2092</self-uri><abstract><p>В настоящее время проблема инфекционного эндокардита (ИЭ) сохраняет свое значение для клиницистов разных специальностей, в том числе для ревматологов. Характерной чертой современного ИЭ является его полиэтиологичность, обусловленная широким спектром возбудителей. В лекции подробно освещены клиническая картина болезни, а также данные лабораторных и инструментальных исследований. Представлены современные международные диагностические критерии ИЭ. Выраженный клинический полиморфизм, стертость симптоматики, моносиндромный дебют в виде масок – все это повышает значение дифференциальной диагностики ИЭ, особенно на ранних стадиях болезни. Излагаются основные подходы к разграничению ИЭ с вызывающими наибольшие дифференциально-диагностические проблемы заболеваниями</p></abstract><trans-abstract xml:lang="en"><p>At present, the problem of infective endocarditis (IE) remains relevant for clinicians of different specialties, including rheumatologists. The distinctive feature of present-day IE is its polyetiological pattern due to a broad spectrum of pathogens. The lecture highlights in detail clinical picture of the disease, laboratory and instrumental findings. It presents current international diagnostic criteria for IE. The obvious clinical polymorphism, subtle symptoms, and monosyndromic onset as masks, all increases the significance of differential diagnosis of IE, in early disease stages in particular. Main approaches to differentiating IE from diseases posing the greatest differentially diagnostic challenges are set forth.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>инфекционный эндокардит</kwd><kwd>классификация</kwd><kwd>клиническая картина</kwd><kwd>диагностика</kwd><kwd>дифференциальная диагностика</kwd></kwd-group><kwd-group xml:lang="en"><kwd>infective endocarditis</kwd><kwd>classification</kwd><kwd>clinical presentation</kwd><kwd>diagnosis</kwd><kwd>differential diagnosis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Habib G, Hoen B, Tornos P, et al. Guidelines on the prevention, diagnosis, and treatment of infective endocarditis (new version 2009): the Task Force on the Prevention, Diagnosis, d Treatment of Infective Endocarditis of the European Society of Cardiology (ESC). Endorsed by the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and the International Society of Chemotherapy (ISC) for Infection and Cancer. Eur Heart J. 2009;30(19):2369–413. doi: 10.1093/eurheartj/ehp285</mixed-citation><mixed-citation xml:lang="en">Habib G, Hoen B, Tornos P, et al. Guidelines on the prevention, diagnosis, and treatment of infective endocarditis (new version 2009): the Task Force on the Prevention, Diagnosis, d Treatment of Infective Endocarditis of the European Society of Cardiology (ESC). Endorsed by the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and the International Society of Chemotherapy (ISC) for Infection and Cancer. Eur Heart J. 2009;30(19):2369–413. doi: 10.1093/eurheartj/ehp285</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Hoen B, Duval X. Infective endocarditis. N Engl J Med. 2013;368(15):1425–33. doi: 10.1056/NEJMcp1206782</mixed-citation><mixed-citation xml:lang="en">Hoen B, Duval X. Infective endocarditis. N Engl J Med. 2013;368(15):1425–33. doi: 10.1056/NEJMcp1206782</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Morris NA, Matiello M, Lyons JL, Samuels MA. Neurologic complications in infective endocarditis: identification, management, and impact on cardiac surgery. Neurohospitalist. 2014;4(4):213–22. doi: 10.1177/1941874414537077</mixed-citation><mixed-citation xml:lang="en">Morris NA, Matiello M, Lyons JL, Samuels MA. Neurologic complications in infective endocarditis: identification, management, and impact on cardiac surgery. Neurohospitalist. 2014;4(4):213–22. doi: 10.1177/1941874414537077</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Yu CW, Juan LI, Hsu SC, et al. Role of procalcitonin in the diagnosis of infective endocarditis: a meta-analysis. Am J Emerg Med. 2013;31(6):935–41. doi: 10.1016/j.ajem.2013.03.008</mixed-citation><mixed-citation xml:lang="en">Yu CW, Juan LI, Hsu SC, et al. Role of procalcitonin in the diagnosis of infective endocarditis: a meta-analysis. Am J Emerg Med. 2013;31(6):935–41. doi: 10.1016/j.ajem.2013.03.008</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Thuny F, Grisoli D, Cautela J, et al. Infective endocarditis: prevention, diagnosis, and management. Can J Cardiol. 2014;30(9):1046–57. doi: 10.1016/j.cjca.2014.03.042</mixed-citation><mixed-citation xml:lang="en">Thuny F, Grisoli D, Cautela J, et al. Infective endocarditis: prevention, diagnosis, and management. Can J Cardiol. 2014;30(9):1046–57. doi: 10.1016/j.cjca.2014.03.042</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Melgar GR, Nasser RM, Gordon SM, et al. Fungal prosthetic valve endocarditis in 16 patients: an 11-year experience in a tertiary care hospital. Medicine. 1997;76(2): 94–103. doi: 10.1097/00005792-199703000-00002</mixed-citation><mixed-citation xml:lang="en">Melgar GR, Nasser RM, Gordon SM, et al. Fungal prosthetic valve endocarditis in 16 patients: an 11-year experience in a tertiary care hospital. Medicine. 1997;76(2): 94–103. doi: 10.1097/00005792-199703000-00002</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Fowler VG, Bayer A. Infective endocarditis. In: Goldman L, Schafer AI, editors. Goldman's Cecil Medicine. 24th ed. Philadelphia: Saunders; 2012. P. 464–73.</mixed-citation><mixed-citation xml:lang="en">Fowler VG, Bayer A. Infective endocarditis. In: Goldman L, Schafer AI, editors. Goldman's Cecil Medicine. 24th ed. Philadelphia: Saunders; 2012. P. 464–73.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Bashore TM. Infective endocarditis. In: Otto CM, Bonow RO, editors. Valvular heart disease. 4th ed. Philadelphia: Saunders; 2014. P. 396–419.</mixed-citation><mixed-citation xml:lang="en">Bashore TM. Infective endocarditis. In: Otto CM, Bonow RO, editors. Valvular heart disease. 4th ed. Philadelphia: Saunders; 2014. P. 396–419.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Faber M, Frimodt-Moller N, Espersen F, et al. Staphylococcus aureus endocarditis in Danish intravenous drug users: high proportion of left-sided endocarditis. Scand J Infect Dis. 1995;27:483–7. doi: 10.3109/00365549509047050</mixed-citation><mixed-citation xml:lang="en">Faber M, Frimodt-Moller N, Espersen F, et al. Staphylococcus aureus endocarditis in Danish intravenous drug users: high proportion of left-sided endocarditis. Scand J Infect Dis. 1995;27:483–7. doi: 10.3109/00365549509047050</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Bassetti M, Venturini S, Crapis M, et al. Infective endocarditis in elderly: An Italian prospective multi-center observational study. Int J Cardiol. 2014;177(2):636–8. doi: 10.1016/j.ijcard.2014.09.184</mixed-citation><mixed-citation xml:lang="en">Bassetti M, Venturini S, Crapis M, et al. Infective endocarditis in elderly: An Italian prospective multi-center observational study. Int J Cardiol. 2014;177(2):636–8. doi: 10.1016/j.ijcard.2014.09.184</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Li JS, Sexton DJ, Mick N, et al. Proposed modifications to the Duke criteria for the diagnosis of infective endocarditis. Clin Infect Dis. 2000;30(4):633–8. doi: 10.1086/313753</mixed-citation><mixed-citation xml:lang="en">Li JS, Sexton DJ, Mick N, et al. Proposed modifications to the Duke criteria for the diagnosis of infective endocarditis. Clin Infect Dis. 2000;30(4):633–8. doi: 10.1086/313753</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Тарасова ГМ. Инфекционный эндокардит: ревматологические аспекты: Автореф. дис. ... канд. мед. наук. Москва; 2010. 26 с. [Tarasova GM. Infektsionnyy endokardit: revmatologicheskie aspekty: Avtoref. dis. ... kand. med. nauk [Infective endocarditis: rheumatological aspects: Diss. ... cand. med. sci.]. Moscow; 2010. 26 p].</mixed-citation><mixed-citation xml:lang="en">Тарасова ГМ. Инфекционный эндокардит: ревматологические аспекты: Автореф. дис. ... канд. мед. наук. Москва; 2010. 26 с. [Tarasova GM. Infektsionnyy endokardit: revmatologicheskie aspekty: Avtoref. dis. ... kand. med. nauk [Infective endocarditis: rheumatological aspects: Diss. ... cand. med. sci.]. Moscow; 2010. 26 p].</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Newburger JW, Takahashi M, Gerber MA, et al. Diagnosis, treatment, and long-term management of Kawasaki disease: a statement for health professionals from the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association. Pediatrics. 2004;114(6):1708–33. doi: 10.1542/peds.2004-2182</mixed-citation><mixed-citation xml:lang="en">Newburger JW, Takahashi M, Gerber MA, et al. Diagnosis, treatment, and long-term management of Kawasaki disease: a statement for health professionals from the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association. Pediatrics. 2004;114(6):1708–33. doi: 10.1542/peds.2004-2182</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Сугралиев АБ, Арабидзе ГГ, Насонов ЕЛ и др. Септический эндокардит при неспецифическом аортоартериите. Клиническая медицина. 2003;(1):69–73 [Sugraliev AB, Arabidze GG, Nasonov EL, et al. Bacterial endocarditis in non-specific aortoarteriit. Klinicheskaya meditsina. 2003;(1):69–73 (In Russ.)].</mixed-citation><mixed-citation xml:lang="en">Сугралиев АБ, Арабидзе ГГ, Насонов ЕЛ и др. Септический эндокардит при неспецифическом аортоартериите. Клиническая медицина. 2003;(1):69–73 [Sugraliev AB, Arabidze GG, Nasonov EL, et al. Bacterial endocarditis in non-specific aortoarteriit. Klinicheskaya meditsina. 2003;(1):69–73 (In Russ.)].</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
