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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rsp</journal-id><journal-title-group><journal-title xml:lang="ru">Научно-практическая ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Rheumatology Science and Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-4484</issn><issn pub-type="epub">1995-4492</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1995-4484-2015-456-459</article-id><article-id custom-type="elpub" pub-id-type="custom">rsp-2119</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НАБЛЮДЕНИЯ ИЗ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL NOTES</subject></subj-group></article-categories><title-group><article-title>Случай вызванной лефлуномидом клинико-морфологической регрессии АА-амилоидоза и ремиссии болезни Стилла взрослых</article-title><trans-title-group xml:lang="en"><trans-title>CASE OF LEFLUNOMIDE-INDUCED CLINICAL AND MORPHOLOGICAL REGRESSION OF AA-AMYLOIDOSIS AND REMISSION OF ADULT-ONSET STILL'S DISEASE</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Муравьев</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Muravyev</surname><given-names>Yu. V.</given-names></name></name-alternatives><email xlink:type="simple">murawyu@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алексеева</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Alekseeva</surname><given-names>A. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Раденска-Лоповок</surname><given-names>С. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Radenska-Lopovok</surname><given-names>S. G.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лебедева</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Lebedeva</surname><given-names>V. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ Научно- исследовательский институт ревматологии им. В.А. Насоновой, Москва, Россия 115522 Москва,  Каширское шоссе, 34А</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia 34A, Kashirskoe Shosse, Moscow 115522</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>10</day><month>09</month><year>2015</year></pub-date><volume>53</volume><issue>4</issue><fpage>456</fpage><lpage>459</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Муравьев Ю.В., Алексеева А.В., Раденска-Лоповок С.Г., Лебедева В.В., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Муравьев Ю.В., Алексеева А.В., Раденска-Лоповок С.Г., Лебедева В.В.</copyright-holder><copyright-holder xml:lang="en">Muravyev Y.V., Alekseeva A.V., Radenska-Lopovok S.G., Lebedeva V.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://rsp.mediar-press.net/rsp/article/view/2119">https://rsp.mediar-press.net/rsp/article/view/2119</self-uri><abstract><p>Описано многолетнее наблюдение, с обсуждением возможного механизма, индуцированной лефлуномидом клинико-морфологической регрессии АА-амилоидоза, диагностированного на нефротической стадии, при болезни Стилла, развившейся у взрослых.</p></abstract><trans-abstract xml:lang="en"><p>The paper describes a long-term observation and discusses the possible mechanism of leflunomide-induced clinical and morphological regression of AA-amyloidosis diagnosed at a nephrotic stage in the presence of adult-onset Still's disease.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>АА-амилоидоз</kwd><kwd>болезнь Стилла</kwd><kwd>развившаяся у взрослых</kwd><kwd>лефлуномид</kwd><kwd>ремиссия</kwd><kwd>сывороточный амилоид A.</kwd></kwd-group><kwd-group xml:lang="en"><kwd>AA-amyloidosis</kwd><kwd>adult-onset Still’s disease</kwd><kwd>leflunomide</kwd><kwd>remission</kwd><kwd>serum amyloid A.</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Муравьев ЮВ, Алексеева АВ, Раденска-Лоповок СГ. 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