rspНаучно-практическая ревматологияRheumatology Science and Practice1995-44841995-4492IMA-PRESS, LLC10.14412/1995-4484-2016-244-246rsp-2205Research ArticleПЕРЕДОВАЯFRONTIERSБолезнь Бехчета: этнос и семейная агрегацияBEHСET'S DISEASE: ETHNOS AND FAMILIAL AGGREGATIONАлекбероваЗ. С.AlekberovaZ. S.

115522 Москва, Каширское шоссе, 34А

34A, Kashirskoe Shosse, Moscow 115522

sokrat@irramn.ruФГБНУ Научно-исследовательский институт ревматологии им. В.А. НасоновойРоссияV.A. Nasonova Research Institute of RheumatologyRussian Federation201618072016543244246Copyright © Алекберова З.С., 20162016Алекберова З.С.Alekberova Z.S.This work is licensed under a Creative Commons Attribution 4.0 License.https://rsp.mediar-press.net/rsp/article/view/2205

Семейная агрегация (повторные случаи заболевания в семьях пробандов) рассматривается как аргумент в пользу генетической природы болезни Бехчета (ББ). Результаты опроса 180 больных с ББ в трех этнических группах показали, что повторные случаи рецидивирующего афтозного стоматита (РАС) имелись в 54 семьях (30%): чаще – среди дагестанцев (n=32), реже – у чеченцев (n=12) и у русских (n=10). Таким образом, родственники пробанда с РАС должны быть включены в группу риска по ББ.

Familial aggregation (repeated cases of the disease in the families of probands) is considered as an argument in favor of the genetic nature of Behсet's disease (BD). The results of a survey of 180 patients with BD in three ethnic groups indicated that there were repeated cases of recurrent aphthous stomatitis (RAS) in 54 (30%) families: more commonly among Dagestanis (n =32), less commonly in Chechens (n = 12) and Russians (10). Thus, the relatives of the RAS proband should be included in a group at risk for BD.

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The authors declare that there are no conflicts of interest present.