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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rsp</journal-id><journal-title-group><journal-title xml:lang="ru">Научно-практическая ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Rheumatology Science and Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-4484</issn><issn pub-type="epub">1995-4492</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1995-4484-2016-1S-67-74</article-id><article-id custom-type="elpub" pub-id-type="custom">rsp-2256</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group></article-categories><title-group><article-title>ПРИМЕНЕНИЕ НЕСТЕРОИДНЫХ ПРОТИВОВОСПАЛИТЕЛЬНЫХ ПРЕПАРАТОВ ДЛЯ  ЛЕЧЕНИЯ АКСИАЛЬНЫХ СПОНДИЛОАРТРИТОВ, ВКЛЮЧАЯ АНКИЛОЗИРУЮЩИЙ СПОНДИЛИТ, МОНИТОРИНГ ЭФФЕК ТИВНОСТИ И БЕЗОПАСНОСТИ (ПРОЕК Т РЕКОМЕНДАЦИЙ ГРУППЫ ЭКСПЕРТОВ ПО ДИАГНОСТИКЕ И ЛЕЧЕНИЮ СПОНДИЛОАРТРИТОВ)</article-title><trans-title-group xml:lang="en"><trans-title>USE OF NONSTEROIDAL ANTI-INFLAMMATORY DRUGS FOR THE TREATMENT OF AXIAL SPONDYLOARTHRITIS, INCLUDING ANKYLOSING SPONDYLITIS, MONITORING THEIR EFFICACY AND SAFETY (DRAFT GUIDELINES OF THE EXPERT SPONDYLOARTHRITIS DIAGNOSIS AND TREATMENT GROUP)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гайдукова</surname><given-names>И. З.</given-names></name><name name-style="western" xml:lang="en"><surname>Gaidukova</surname><given-names>I. Z.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ребров</surname><given-names>А. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Rebrov</surname><given-names>A. P.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Оттева</surname><given-names>Э. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Otteva</surname><given-names>E. N.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бадокин</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Badokin</surname><given-names>V. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бочкова</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Bochkova</surname><given-names>A. G.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бугрова</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Bugrova</surname><given-names>O. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Годзенко</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Godzenko</surname><given-names>A. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дубиков</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Dubikov</surname><given-names>A. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-6"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дубинина</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Dubinina</surname><given-names>T. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-7"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванова</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanova</surname><given-names>O. N.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-8"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коротаева</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Korotaeva</surname><given-names>T. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-9"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лапшина</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Lapshina</surname><given-names>S. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-10"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Несмеянова</surname><given-names>О. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Nesmeyanova</surname><given-names>O. B.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-11"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никишина</surname><given-names>И. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikishina</surname><given-names>I. P.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-9"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Раскина</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Raskina</surname><given-names>T. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-12"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Румянцева</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Rumyantseva</surname><given-names>O. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-9"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Смирнов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Smirnov</surname><given-names>A. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-9"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ситало</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sitalo</surname><given-names>A. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-13"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Эрдес</surname><given-names>Ш. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Erdes</surname><given-names>Sh. F.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><email xlink:type="simple">123456_57@mail.ru</email><xref ref-type="aff" rid="aff-9"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Саратовский государственный медицинский университет  имени В.И. Разумовского Минздрав России, Саратов</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.I. Razumovsky Saratov State Medical University, Ministry of Health of Russia, Saratov</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Институт повышения квалификации специалистов здравоохранения, Минздрав Хабаровского края, Хабаровск</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Institute for Advanced Training of Healthcare Specialists, Ministry of Health of the Khabarovsk Territory, Khabarovsk</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Российская медицинская академия постдипломного образования, Минздрав  России, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Medical Academy of Postgraduate Education, Ministry of Health of Russia, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Медицинский центр «Агат», Егорьевск</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Agat Medical Center, Egoryevsk, Moscow Region</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>Оренбургский государственный медицинский университет, Минздрав России, Оренбург</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Medical Academy of Postgraduate Education, Ministry of Health of Russia, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-6"><aff xml:lang="ru"><institution>Тихоокеанский государственный медицинский университет, Минздрава России, Владивосток</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.A. Nasonova Research Institute of Rheumatology, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><aff xml:lang="ru" id="aff-7"><institution>Научно-исследовательский институт ревматологии имени В.А. Насоновой, Москва</institution><country>Russian Federation</country></aff><aff-alternatives id="aff-8"><aff xml:lang="ru"><institution>Воронежская областная клиническая больница №1, Воронеж</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Voronezh Regional Clinical Hospital One, Voronezh</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-9"><aff xml:lang="ru"><institution>Научно-исследовательский институт ревматологии имени В.А. Насоновой, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.A. Nasonova Research Institute of Rheumatology, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-10"><aff xml:lang="ru"><institution>Казанский государственный медицинский университет, Минздрава России, Казань</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kazan State Medical University, Ministry of Health of Russia; Kazan</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-11"><aff xml:lang="ru"><institution>Челябинская областная клиническая больница, Челябинск</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Chelyabinsk Regional Clinical Hospital, Chelyabinsk</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-12"><aff xml:lang="ru"><institution>Кемеровская государственная медицинская академия, Минздрав России, Кемерово</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kemerovo State Medical Academy, Ministry of Health of Russia, Kemerovo</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-13"><aff xml:lang="ru"><institution>Общество взаимопомощи при болезни Бехтерева, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Society of Mutual Assistance in Bechterew’s Disease, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>16</day><month>09</month><year>2016</year></pub-date><volume>54</volume><issue>1S</issue><issue-title>приложение 1</issue-title><fpage>67</fpage><lpage>74</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Гайдукова И.З., Ребров А.П., Оттева Э.Н., Бадокин В.В., Бочкова А.Г., Бугрова О.В., Годзенко А.А., Дубиков А.А., Дубинина Т.В., Иванова О.Н., Коротаева Т.В., Лапшина С.А., Несмеянова О.Б., Никишина И.П., Раскина Т.А., Румянцева О.А., Смирнов А.В., Ситало А.В., Эрдес Ш.В., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Гайдукова И.З., Ребров А.П., Оттева Э.Н., Бадокин В.В., Бочкова А.Г., Бугрова О.В., Годзенко А.А., Дубиков А.А., Дубинина Т.В., Иванова О.Н., Коротаева Т.В., Лапшина С.А., Несмеянова О.Б., Никишина И.П., Раскина Т.А., Румянцева О.А., Смирнов А.В., Ситало А.В., Эрдес Ш.В.</copyright-holder><copyright-holder xml:lang="en">Gaidukova I.Z., Rebrov A.P., Otteva E.N., Badokin V.V., Bochkova A.G., Bugrova O.V., Godzenko A.A., Dubikov A.A., Dubinina T.V., Ivanova O.N., Korotaeva T.V., Lapshina S.A., Nesmeyanova O.B., Nikishina I.P., Raskina T.A., Rumyantseva O.A., Smirnov A.V., Sitalo A.V., Erdes S.F.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://rsp.mediar-press.net/rsp/article/view/2256">https://rsp.mediar-press.net/rsp/article/view/2256</self-uri><abstract><p>Представлен проект рекомендаций, разработанных группой экспертов  по изучению спондилоартритов (ЭкСпА)  по поручению Ассоциации ревматологов России.  Рекомендации включают основные  положения по применению нестероидных противовоспалительных препаратов  при аксиальных спондилоартритах, включая анкилозирующий спондилит, содержат указания  по длительности  их применения, описывают  возможную тактику ведения пациентов в наиболее частых клинических ситуациях и предпочтительный алгоритм оценки  эффективности и безопасности лечения.</p></abstract><trans-abstract xml:lang="en"><p>The paper gives the draft guidelines elaborated  by the Expert Spondyloarthritis  Diagnosis and Treatment Group  by order of the Association of Rheumatologists  of Russia. The guidelines include the essentials of how to use nonsteroidal  anti-inflammatory drugs in axial spondyloarthrititides, including ankylosing spondylitis, contain  instructions  for how long they should be administered, and describe possible patient  management tactics in the most common  clinical situations and a preferential  algorithm for evaluating the efficiency and safety of treatment.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>спондилоартриты</kwd><kwd>аксиальные спондилоартриты</kwd><kwd>анкилозирующий спондилит</kwd><kwd>нестероидные  противовоспалительные препараты</kwd><kwd>эффективность терапии</kwd><kwd>ремиссия</kwd><kwd>безопасность терапии</kwd></kwd-group><kwd-group xml:lang="en"><kwd>spondyloarthritis</kwd><kwd>axial spondyloarthritis</kwd><kwd>ankylosing spondylitis</kwd><kwd>nonsteroidal  anti-inflammatory drugs</kwd><kwd>efficiency of therapy</kwd><kwd>remission</kwd><kwd>safety of therapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Эрдес ШФ, Бадокин ВВ, Бочкова АГ и др. 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