rspНаучно-практическая ревматологияRheumatology Science and Practice1995-44841995-4492IMA-PRESS, LLC10.14412/1995-4484-2016-598-600rsp-2309Research ArticleКЛИНИЧЕСКОЕ НАБЛЮДЕНИЕCLINICAL OBSERVATIONSСИНДРОМ КОГАНА. КЛИНИЧЕСКИЕ НАБЛЮДЕНИЯ УСПЕХ ИММУНОСУПРЕССИВНОЙ ТЕРАПИИCOGAN'S SYNDROME: SUCCESS OF IMMUNOSUPPRESSIVE THERAPYМороваН. А.MorovaN. A.

Наталия Александровна Морова.

1644043 Омск, ул. Ленина, 12

Nataliya Morova.

12, LeninSt., Omsk644043

nataliya-morova@yandex.ruКропотинаТ. В.KropotinaT. V.

2644111 Омск, ул. Березовая, 3

3, BerezovayaSt., Omsk 644111

АрбузоваЮ. В.ArbuzovaYu. V.

2644111 Омск, ул. Березовая, 3

3, BerezovayaSt., Omsk 644111

Омский государственный медицинский университетРоссияOmsk State Medical UniversityRussian FederationОбластная клиническая больницаРоссияRegonal Clinical HospitalRussian Federation201609122016545598600Copyright © Морова Н.А., Кропотина Т.В., Арбузова Ю.В., 20162016Морова Н.А., Кропотина Т.В., Арбузова Ю.В.Morova N.A., Kropotina T.V., Arbuzova Y.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://rsp.mediar-press.net/rsp/article/view/2309

Синдром  Когана – редкое заболевание из группы системных васкулитов с вариабельным поражением сосудов. Представляет  собой сочетание  офтальмологических симптомов  и аудиовестибулярных расстройств (синдром  Меньера и сенсоневральная тугоухость). Часто наблюдаются  лихорадка, артралгии или артрит, встречаются неврологические нарушения, аортит с развитием  аневризмы аорты. Потеря  слуха часто бывает необратимой. Изменения со стороны органа зрения обычно протекают благоприятно.

Cogan's syndrome is a rare disease from a group of systemic vasculitides with variable vascular involvement. It is a concurrence of ophthalmic  symptoms and audiovestibular disorders (Meniere's disease and sensorineural hearing loss). There is often fever, arthralgia or arthritis; neurological disorders and aortitis with the development of aortic aneurysms are encountered. Hearing loss is frequently irreversible. Changes in the organ of vision usually occur favorably.

The paper describes a case of Cogan's syndrome in a 33-year-old  patient. The disease is manifested by papilledema, conjunctivitis, acute sensorineural deafness with rapid loss of hearing, and microfocal changes in the brain, as detected by computed  tomography. Pulse therapy with glucocorticoids  and cyclophosphamide led to a rapid and obvious regression of all symptoms. The case is of interest due to the rare occurrence  of the disease and to the success of performed therapy. The description stresses the importance  of a rheumatologist's  consultation  and the need for the collective management of young patients with clinical presentations  of acute sensorineural hearing loss.

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The authors declare that there are no conflicts of interest present.