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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rsp</journal-id><journal-title-group><journal-title xml:lang="ru">Научно-практическая ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Rheumatology Science and Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-4484</issn><issn pub-type="epub">1995-4492</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1995-4484-2017-138-150</article-id><article-id custom-type="elpub" pub-id-type="custom">rsp-2355</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>МЕЖДУНАРОДНЫЕ И РОССИЙСКИЕ РЕКОМЕНДАЦИИ ПО ЛЕЧЕНИЮ РЕВМАТИЧЕСКИХ ЗАБОЛЕВАНИЙ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>INTERNATIONAL AND RUSSIAN GUIDELINES FOR THE TREATMENT OF RHEUMATIC DISEASES</subject></subj-group></article-categories><title-group><article-title>Рекомендации EULAR по диагностике и лечению раннего артрита: 2016</article-title><trans-title-group xml:lang="en"><trans-title>THE 2016 EULAR GUIDELINES FOR THE DIAGNOSIS AND TREATMENT OF EARLY ARTHRITIS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Насонов</surname><given-names>Е. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Nasonov</surname><given-names>E. L.</given-names></name></name-alternatives><email xlink:type="simple">nasonov@irramn.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>1 ФГБНУ «Научно- исследовательский институт ревматологии им. В.А. Насоновой», Москва&#13;
2 ФГБОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России, кафедра ревматологии Института профессионального образования, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>1 V.A. Nasonova Research Institute of Rheumatology, Moscow,&#13;
2 Department of Rheumatology, Institute of Professional Education, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>24</day><month>04</month><year>2017</year></pub-date><volume>55</volume><issue>2</issue><fpage>138</fpage><lpage>150</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Насонов Е.Л., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Насонов Е.Л.</copyright-holder><copyright-holder xml:lang="en">Nasonov E.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://rsp.mediar-press.net/rsp/article/view/2355">https://rsp.mediar-press.net/rsp/article/view/2355</self-uri><abstract><p>Ранний артрит, который часто определяют как недифференцированный артрит (НДА), может быть ран- ней стадией ревматоидного артрита (РА), первым проявлением широкого спектра ревматических заболеваний и в течение длительного времени оставаться недифференцированным или завершаться спонтанно. В статье обсуждаются новые рекомендации Европейской антиревматической лиги (EULAR) по ведению пациентов с ранним артритом, в которых отражены достижения за последние 10 лет, связанные с новыми методами диагностики и лечения раннего артрита, в первую очередь – как кардинального симптомокомплекса РА. Рекомендации включают три общих принципа и 12 рекомендаций, касающихся диагностики и лечения раннего артрита. Особое внимание уделяется необходимости раннего назначения метотрексата, монотерапия которым является «золотым стандартом» в фармакотерапии РА. В заключение обсуждаются новые данные, касающиеся возможности профилактики РА в группе пациентов с АЦЦП-позитивными артралгиями.</p><sec><title> </title><p> </p></sec><sec><title> </title><p> </p></sec></abstract><trans-abstract xml:lang="en"><p>Early arthritis, which is frequently defined as undifferentiated arthritis, can be an early stage of rheumatoid arthritis (RA), the first manifestation of a wide spectrum of rheumatic diseases and remain undifferentiated for a long time or end spontaneously. The article discusses new European League Against Rheumatism (EULAR) guidelines for the management of patients with early arthritis, which reflect the past decade's advances in new methods for the diagnosis and treatment of early arthritis primarily as a cardinal RA symptom complex. The guidelines include three general principles and 12 recommendations for the diagnosis and treatment of early arthritis. Special attention is given to the need for early use of methotrexate, monotherapy with the latter is the gold standard for the pharmacotherapy of RA. In conclusion, the paper discusses new evidence for the possibilities of preventing RA in a group of anti-cyclic citrullinated peptide antibodies positive patients with arthralgias.</p><p> </p></trans-abstract><kwd-group xml:lang="ru"><kwd>ранний артрит</kwd><kwd>ревматоидный артрит</kwd><kwd>метотрексат</kwd><kwd>антитела к циклическому цитруллини- рованному пептиду</kwd></kwd-group><kwd-group xml:lang="en"><kwd>early arthritis</kwd><kwd>rheumatoid arthritis</kwd><kwd>methotrexate</kwd><kwd>anti-cyclic citrullinated peptide antibodies</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Machado P, Castrejon I, Katchamart W, et al. 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Ann Rheum Dis. 2010;69(3):490-4. doi: 10.1136/ard.2008.105759</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
