rspНаучно-практическая ревматологияRheumatology Science and Practice1995-44841995-4492IMA-PRESS, LLC10.14412/1995-4484-2017-211-217rsp-2365Research ArticleОБЗОРREVIEWАутоиммунные заболевания и дисфункция щитовидной железы при ревматоидном артритеAUTOIMMUNE DISEASES AND THYROID DYSFUNCTION IN RHEUMATOID ARTHRITISКондратьеваЛ. В.KondratyevaL. V.kondratyeva.liubov@yandex.ruПопковаТ. В.PopkovaT. V.kondratyeva.liubov@yandex.ruФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой», МоскваРоссияV.A. Nasonova Research Institute of Rheumatology, MoscowRussian Federation201724042017552211217Copyright © Кондратьева Л.В., Попкова Т.В., 20172017Кондратьева Л.В., Попкова Т.В.Kondratyeva L.V., Popkova T.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://rsp.mediar-press.net/rsp/article/view/2365

В обзоре литературы рассматриваются различные аспекты сочетания ревматоидного артрита (РА) с аутоиммунными заболеваниями щитовидной железы (тиреоидитом Хашимото и болезнью Грейвса). Обсуждаются распространенность, генетическая предрасположенность, сходство патогенеза и клинических симптомов, а также способность органоспецифичных аутоантител (антител к тиреоидной пероксидазе, антител к тиреоглобулину) и гипотиреоза влиять на течение РА и риск кардиоваскулярых осложнений.

 

The literature review deals with various aspects of the concurrence of rheumatoid arthritis (RA) and autoimmune thyroid diseases (Hashimoto's thyroiditis and Graves' disease). It discusses the prevalence, genetic predisposition, similarity of pathogenesis and clinical symptoms, as well as the ability of organ-specific autoantibodies (anti-thyroid peroxidase antibodies, anti-thyroglobulin antibodies) and hypothyroidism to affect the course of RA and the risk of cardiovascular complications.

 

ревматоидный артритаутоиммунные заболевания щитовидной железытиреоидит Хашимотоболезнь Грейвсаантитела к тиреоидной пероксидазеантитела к тиреоглобулинугипотиреозкардиоваскулярные заболеванияrheumatoid arthritisautoimmune thyroid diseaseHashimoto's thyroiditisGraves' diseaseanti-thyroid peroxidase antibodiesanti-thyroglobulin autoantibodieshypothyroidismcardiovascular diseasesReferencesНасонов ЕЛ, редактор. Ревматология. Клинические рекомендации. Москва: ГЭОТАР-Медиа; 2010 [Nasonov EL, editor. Revmatologiya. Klinicheskie rekomendatsii [Rheumatology. Clinical guidelines]. Moscow: GEOTAR-Media; 2010].Насонов ЕЛ, редактор. Ревматология. Клинические рекомендации. Москва: ГЭОТАР-Медиа; 2010 [Nasonov EL, editor. Revmatologiya. Klinicheskie rekomendatsii [Rheumatology. Clinical guidelines]. Moscow: GEOTAR-Media; 2010].Александрова ЕН, Авдеева АС, Лукина ГВ и др. Клинико- иммунологические эффекты анти-В-клеточной терапии у больных ревматоидным артритом. 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The authors declare that there are no conflicts of interest present.