rspНаучно-практическая ревматологияRheumatology Science and Practice1995-44841995-4492IMA-PRESS, LLC10.14412/1995-4484-2017-526-535rsp-2436Research ArticleПРОГРАММА НЕПРЕРЫВНОГО ПОСЛЕДИПЛОМНОГО ОБРАЗОВАНИЯ ВРАЧЕЙPOSTGRADUATE PROGRAM OF CONTINUING MEDICAL EDUCATIONСистемная красная волчанка с ювенильным дебютом: особенности клинической картины и современные подходы к диагностикеJUVENILE-ONSET SYSTEMIC LUPUS ERYTHEMATOSUS: CLINICAL FEATURES AND CURRENT DIAGNOSTIC APPROACHESКаледаМ. И.KaledaM. I.

старший научный сотрудник лаборатории ревматических заболеваний  детского возраста с реабилитационной группой ФГБНУ НИИР им. В.А.  Насоновой, канд. мед. наук

Москва, Россия 115522 Москва, Каширское шоссе, 34А

Russia 34A, Kashirskoe Shosse, Moscow 115522

kaleda-mi@yandex.ruНикишинаИ. П.NikishinaI. P.

заведующая лабораторией ревматических заболеваний детского возраста с реабилитационной группой ФГБНУ НИИР им. В.А. Насоновой, канд. мед. наук

Москва, Россия 115522 Москва, Каширское шоссе, 34А

Russia 34A, Kashirskoe Shosse, Moscow 115522

ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»РоссияV.A. Nasonova Research Institute of RheumatologyRussian Federation201727102017555526535Copyright © Каледа М.И., Никишина И.П., 20172017Каледа М.И., Никишина И.П.Kaleda M.I., Nikishina I.P.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://rsp.mediar-press.net/rsp/article/view/2436

Системная красная волчанка (СКВ) – аутоиммунное заболевание с вовлечением в патологический процесс различных органов и систем, непрогнозируемым течением, риском развития жизнеугрожающих состояний, которое в 10–20% случаев дебютирует в детском и подростковом возрасте. Начало СКВ до наступления совершеннолетия влияет на клинические проявления, особенности течения и прогноз. На основе анализа данных литературы в статье анализируются особенности дебюта и клинической картины СКВ у детей и подростков, обсуждаются аспекты верификации диагноза с учетом необходимости раннего назначения эффективной персонифицированной терапии и улучшения прогноза.

Systemic lupus erythematosus (SLE) is an autoimmune disease with various organs and systems involved in the pathological process, with an unpredictable course, a risk for life-threatening conditions, and an onset from childhood through adolescence in 10–20% of cases. The onset of SLE prior to adult age affects its clinical manifestations, course, and prognosis. Based on the data available in the literature, the paper analyzes the features of the onset and clinical presentations of SLE in children and adolescents and discusses the aspects of verifying its diagnosis, by taking into account the need to use early effective personalized therapy and to improve prognosis.

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The authors declare that there are no conflicts of interest present.