rspНаучно-практическая ревматологияRheumatology Science and Practice1995-44841995-4492IMA-PRESS, LLC10.14412/1995-4484-2018-93-98rsp-2505Research ArticleОБЗОРЫОстеоартрит и депрессияOSTEOARTHRITIS AND DEPRESSIONКоршуновН. И.KorshunovN. I.

Ярославль.

Yaroslavl.

kor550@yandex.ruРечкинаЕ. В.RechkinaE. V.

Ярославль.

Yaroslavl.

ФилатоваЮ. С.FilatovaYu. S.

Ярославль.

Yaroslavl.

ЯльцеваН. В.YaltsevaN. V.

Ярославль.

Yaroslavl.

ФГБОУ ВО «Ярославский государственный медицинский университет» Минздрава России.РоссияYaroslavl State Medical University, Ministry of Health of Russia.Russian Federation2018040320185619398Copyright © Коршунов Н.И., Речкина Е.В., Филатова Ю.С., Яльцева Н.В., 20182018Коршунов Н.И., Речкина Е.В., Филатова Ю.С., Яльцева Н.В.Korshunov N.I., Rechkina E.V., Filatova Y.S., Yaltseva N.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://rsp.mediar-press.net/rsp/article/view/2505

В обзоре рассматривается проблема коморбидности остеоартрита (ОА) и депрессии. Показано, что у больных ОА депрессия часто является компонентом известной триады «боль – депрессия – нарушения сна», нередко определяя функциональные способности и качество жизни. Наличие тревоги и депрессии может повышать риск неудовлетворительных результатов артропластики. Наличие у больных внешних стрессорных факторов требует биопсихосоциального подхода, определяя возможности медикаментозного и немедикаментозного воздействия. Однако, несмотря на достаточно большое количество работ, посвященных проблеме депрессии у больных ОА, остается много нерешенных вопросов, касающихся как ее роли в развитии болезни, так и подходов к терапии.

The review considers the problem of comorbidity of osteoarthritis (OA) and depression. The latter in OA patients is shown to be commonly a component of the well-known triad of pain – depression – sleep disorders, frequently determining the functional abilities and quality of life. The presence of anxiety and depression may increase the risk for poor outcomes of arthroplasty. Environmental stressors in patients require a biopsychosocial approach, by determining the possibilities of drug and non-drug treatment. However, despite the relatively large number of works dedicated to the problem of depression in patients with OA, there are many unsolved questions regarding both its role in the development of the disease and approaches to therapy.

остеоартритдепрессияosteoarthritisdepressionReferencesKapidzic-Basic N, Kikanovic S, Hotic-Hadziefendic A, Dzananovic D. [Changes in social relations as a consequence of rheumatoid arthritis and osteoarthritis]. Reumatizam. 2013;60(1):42-6 (In Croat.).Kapidzic-Basic N, Kikanovic S, Hotic-Hadziefendic A, Dzananovic D. [Changes in social relations as a consequence of rheumatoid arthritis and osteoarthritis]. Reumatizam. 2013;60(1):42-6 (In Croat.).Алексеенко ЕЮ. Тревожно-депрессивные расстройства у больных первичным oстеоартрозом. Сибирский медицинский журнал (Иркутск). 2014;(7):70-1 [Alekseenko EYu. Anxiety and depressive disorders in patients with primary osteoarthritis. Sibirsky Medicinsky Journal (Irkutsk). 2014;(7):70-1 (In Russ.)].Алексеенко ЕЮ. Тревожно-депрессивные расстройства у больных первичным oстеоартрозом. Сибирский медицинский журнал (Иркутск). 2014;(7):70-1 [Alekseenko EYu. Anxiety and depressive disorders in patients with primary osteoarthritis. Sibirsky Medicinsky Journal (Irkutsk). 2014;(7):70-1 (In Russ.)].Попов АА, Изможерова НВ, Гаврилова ЕИ и др. Влияние коморбидной депрессии на качество жизни женщин в климактерии, страдающих остеартрозом коленных суставов. Российский семейный врач. 2008;12(1):47-50 [Popov AA, Izmojerova NV, Gavrilova EI, et al. The effect of comorbid depression on the quality of life of women in menopause, suffering from ostearthrosis of the knee joints. Rossisky Semeiny Vrach. 2008;12(1):47-50 (In Russ.)].Попов АА, Изможерова НВ, Гаврилова ЕИ и др. Влияние коморбидной депрессии на качество жизни женщин в климактерии, страдающих остеартрозом коленных суставов. Российский семейный врач. 2008;12(1):47-50 [Popov AA, Izmojerova NV, Gavrilova EI, et al. The effect of comorbid depression on the quality of life of women in menopause, suffering from ostearthrosis of the knee joints. Rossisky Semeiny Vrach. 2008;12(1):47-50 (In Russ.)].Stubbs B, Aluko Y, Myint PK, Smith TO. Prevalence of depressive symptoms and anxiety in osteoarthritis: a systematic review and meta-analysis. Age Ageing. 2016 Mar;45(2):228-35. doi: 10.1093/ageing/afw001. Review.Stubbs B, Aluko Y, Myint PK, Smith TO. Prevalence of depressive symptoms and anxiety in osteoarthritis: a systematic review and meta-analysis. Age Ageing. 2016 Mar;45(2):228-35. doi: 10.1093/ageing/afw001. Review.Wong ST, Manca D, Barber D, et al. The diagnosis of depression and its treatment in Canadian primary care practices: an epidemiological study. CMAJ Open. 2014 Oct 1;2(4):E337-42. doi: 10.9778/cmajo.2014005Wong ST, Manca D, Barber D, et al. The diagnosis of depression and its treatment in Canadian primary care practices: an epidemiological study. CMAJ Open. 2014 Oct 1;2(4):E337-42. doi: 10.9778/cmajo.2014005Xu X, Mishra GD, Jones M. Evidence on multimorbidity from definition to intervention: An overview of systematic reviews. Ageing Res Rev. 2017 Aug;37:53-68. doi: 10.1016/j.arr.2017.05.003. Epub 2017 May 13. Review.Xu X, Mishra GD, Jones M. Evidence on multimorbidity from definition to intervention: An overview of systematic reviews. Ageing Res Rev. 2017 Aug;37:53-68. doi: 10.1016/j.arr.2017.05.003. Epub 2017 May 13. Review.Кашеварова НГ, Алексеева ЛИ. Факторы риска прогрессирования остеоартроза коленных суставов. Научно-практическая ревматология. 2014;52(5):553-61 [Kashevarova NG, Alekseeva LI. Risk factors of progressing for knee osteoarthritis. Nauchno-Prakticheskaya Revmatologiya = Rheumatology Science and Practice. 2014;52(5):553-61 (In Russ.)].Кашеварова НГ, Алексеева ЛИ. Факторы риска прогрессирования остеоартроза коленных суставов. Научно-практическая ревматология. 2014;52(5):553-61 [Kashevarova NG, Alekseeva LI. Risk factors of progressing for knee osteoarthritis. Nauchno-Prakticheskaya Revmatologiya = Rheumatology Science and Practice. 2014;52(5):553-61 (In Russ.)].Pereira D, Severo M, Barros H, et al. The effect of depressive symptoms on the association between radiographic osteoarthritis and knee pain: a cross-sectional study. BMC Musculoskelet Disord. 2013 Jul 22;14:214. doi: 10.1186/1471-2474-14-214Pereira D, Severo M, Barros H, et al. The effect of depressive symptoms on the association between radiographic osteoarthritis and knee pain: a cross-sectional study. BMC Musculoskelet Disord. 2013 Jul 22;14:214. doi: 10.1186/1471-2474-14-214Rathbun AM, Yau MS, Shardell M, et al. Depressive symptoms and structural disease progression in knee osteoarthritis: data from the Osteoarthritis Initiative. Clin Rheumatol. 2017 Jan;36(1):15563. doi: 10.1007/s10067-016-3495-3Rathbun AM, Yau MS, Shardell M, et al. Depressive symptoms and structural disease progression in knee osteoarthritis: data from the Osteoarthritis Initiative. Clin Rheumatol. 2017 Jan;36(1):15563. doi: 10.1007/s10067-016-3495-3Veronese N, Stubbs B, Solmi M, et al. Association between lower limb osteoarthritis and incidence of depressive symptoms: data from the osteoarthritis initiative. Age Ageing. 2017 May 1;46(3):470-6. doi: 10.1093/ageing/afw216Veronese N, Stubbs B, Solmi M, et al. Association between lower limb osteoarthritis and incidence of depressive symptoms: data from the osteoarthritis initiative. Age Ageing. 2017 May 1;46(3):470-6. doi: 10.1093/ageing/afw216Veronese N, Stubbs B, Solmi M, et al. Mitochondrial genetic haplogroups and depressive symptoms: A large study among people in North America. J Affect Disord. 2017 Aug 1;217:55-9. doi: 10.1016/j.jad.2017.03.069Veronese N, Stubbs B, Solmi M, et al. Mitochondrial genetic haplogroups and depressive symptoms: A large study among people in North America. J Affect Disord. 2017 Aug 1;217:55-9. doi: 10.1016/j.jad.2017.03.069Rayahin JE, Chmiel JS, Hayes KW, et al. Factors associated with pain experience outcome in knee osteoarthritis. Arthritis Care Res (Hoboken). 2014 Dec;66(12):1828-35. doi: 10.1002/acr.22402Rayahin JE, Chmiel JS, Hayes KW, et al. Factors associated with pain experience outcome in knee osteoarthritis. Arthritis Care Res (Hoboken). 2014 Dec;66(12):1828-35. doi: 10.1002/acr.22402Collins JE, Katz JN, Dervan EE, Losina E. Trajectories and risk profiles of pain in persons with radiographic, symptomatic knee osteoarthritis: data from the osteoarthritis initiative. Osteoarthritis Cartilage. 2014 May;22(5):622-30. doi: 10.1016/j.joca.2014.03.009Collins JE, Katz JN, Dervan EE, Losina E. Trajectories and risk profiles of pain in persons with radiographic, symptomatic knee osteoarthritis: data from the osteoarthritis initiative. Osteoarthritis Cartilage. 2014 May;22(5):622-30. doi: 10.1016/j.joca.2014.03.009Tan V, Jinks C, Chew-Graham C, et al. The triple whammy anxiety depression and osteoarthritis in long-term conditions. BMC Fam Pract. 2015 Oct 14;16:163. doi: 10.1186/s12875-015-0346-2Tan V, Jinks C, Chew-Graham C, et al. The triple whammy anxiety depression and osteoarthritis in long-term conditions. BMC Fam Pract. 2015 Oct 14;16:163. doi: 10.1186/s12875-015-0346-2Askхn A, Ozkan A, Tosun A, et al. Quality of life and functional capacity are adversely affected in osteoarthritis patients with neuropathic pain. Kaohsiung J Med Sci. 2017 Mar;33(3):152-8. doi: 10.1016/j.kjms.2016.12.007Askхn A, Ozkan A, Tosun A, et al. Quality of life and functional capacity are adversely affected in osteoarthritis patients with neuropathic pain. Kaohsiung J Med Sci. 2017 Mar;33(3):152-8. doi: 10.1016/j.kjms.2016.12.007Sharma A, Kudesia P, Shi Q, Gandhi R. Anxiety and depression in patients with osteoarthritis: impact and management challenges. Open Access Rheumatol. 2016 Oct 31;8:103-13. doi: 10.2147/OARRR.S93516Sharma A, Kudesia P, Shi Q, Gandhi R. Anxiety and depression in patients with osteoarthritis: impact and management challenges. Open Access Rheumatol. 2016 Oct 31;8:103-13. doi: 10.2147/OARRR.S93516Castrejon I, Chua JR, Pincus T. A RheuMetric physician checklist to quantitate levels of inflammation, damage and distress on 0-10 visual analogue scales. Clin Exp Rheumatol. 2017 Sep-Oct;35 Suppl 107(5):21-5. Epub 2017 Sep 28. Review.Castrejon I, Chua JR, Pincus T. A RheuMetric physician checklist to quantitate levels of inflammation, damage and distress on 0-10 visual analogue scales. Clin Exp Rheumatol. 2017 Sep-Oct;35 Suppl 107(5):21-5. Epub 2017 Sep 28. Review.Ferreira AH, Godoy PB, Oliveira NR, et al. Investigation of depression, anxiety and quality of life in patients with knee osteoarthritis: a comparative study. Rev Bras Reumatol. 2015 Sep Oct;55(5):434-8. doi: 10.1016/j.rbr.2015.03.001Ferreira AH, Godoy PB, Oliveira NR, et al. Investigation of depression, anxiety and quality of life in patients with knee osteoarthritis: a comparative study. Rev Bras Reumatol. 2015 Sep Oct;55(5):434-8. doi: 10.1016/j.rbr.2015.03.001Zdanovec A. Capsule commentary on Agarwal et al., Healthcare Expenditures Associated with Depression among Individuals with Osteoarthritis: Post-Regression Linear Decomposition Approach. J Gen Intern Med. 2015 Dec;30(12):1851. doi: 10.1007/s11606015-3479-zZdanovec A. Capsule commentary on Agarwal et al., Healthcare Expenditures Associated with Depression among Individuals with Osteoarthritis: Post-Regression Linear Decomposition Approach. J Gen Intern Med. 2015 Dec;30(12):1851. doi: 10.1007/s11606015-3479-zAgarwal P, Sambamoorthi U. Healthcare expenditures associated with depressio among individuals with osteoarthritis: post-regression linear decomposition approach. J Gen Intern Med. 2015 Dec;30(12):1803-11. doi: 10.1007/s11606-015-3393-4Agarwal P, Sambamoorthi U. Healthcare expenditures associated with depressio among individuals with osteoarthritis: post-regression linear decomposition approach. J Gen Intern Med. 2015 Dec;30(12):1803-11. doi: 10.1007/s11606-015-3393-4Wagner CJ, Metzger FG, Sievers C, et al. Depression-related treatment and costs in Germany: Do they change with comorbidity? A claims data analysis. J Affect Disord. 2016 Mar 15;193:25766. doi: 10.1016/j.jad.2015.12.068Wagner CJ, Metzger FG, Sievers C, et al. Depression-related treatment and costs in Germany: Do they change with comorbidity? A claims data analysis. J Affect Disord. 2016 Mar 15;193:25766. doi: 10.1016/j.jad.2015.12.068Quach L, Yang FM, Berry SD, et al. Depression, antidepressants, and falls among community-dwelling elderly people: the MOBILIZE Boston study. J Gerontol A Biol Sci Med Sci. 2013 Dec;68(12):1575-81. doi: 10.1093/Gerona/git084Quach L, Yang FM, Berry SD, et al. Depression, antidepressants, and falls among community-dwelling elderly people: the MOBILIZE Boston study. J Gerontol A Biol Sci Med Sci. 2013 Dec;68(12):1575-81. doi: 10.1093/Gerona/git084Kvelde T, McVeigh C, Toson B, et al. Depressive symptomatology as a risk factor for falls in older people: systematic review and meta-analysis. J Am Geriatr Soc. 2013 May;61(5):694-706. doi: 10.1111/jgs.12209Kvelde T, McVeigh C, Toson B, et al. Depressive symptomatology as a risk factor for falls in older people: systematic review and meta-analysis. J Am Geriatr Soc. 2013 May;61(5):694-706. doi: 10.1111/jgs.12209Ozcakir S, Raif SL, Sivrioglu K, Kucukcakir N. Relationship between radiological Severity and clinical and psychological factors in knee osteoarthritis. Clin Rheumatol. 2011 Dec;30(12):1521-6. doi: 10.1007/s10067-011-1768-4Ozcakir S, Raif SL, Sivrioglu K, Kucukcakir N. Relationship between radiological Severity and clinical and psychological factors in knee osteoarthritis. Clin Rheumatol. 2011 Dec;30(12):1521-6. doi: 10.1007/s10067-011-1768-4White DK, Neogi T, Nguyen US, et al. Trajectories of functional decline in knee osteoarthritis: the Osteoarthritis Initiative. Rheumatology (Oxford). 2016 May;55(5):801-8. doi: 10.1093/rheumatology/kev419White DK, Neogi T, Nguyen US, et al. Trajectories of functional decline in knee osteoarthritis: the Osteoarthritis Initiative. Rheumatology (Oxford). 2016 May;55(5):801-8. doi: 10.1093/rheumatology/kev419White DK, Neogi T, Zhang Y, et al. Association of slow gait speed with trajectories of worsening depressive symptoms in knee osteoarthritis: An observational study. Arthritis Care Res (Hoboken). 2017 Feb; 69(2):209-15. doi: 10.1002/acr.22928White DK, Neogi T, Zhang Y, et al. Association of slow gait speed with trajectories of worsening depressive symptoms in knee osteoarthritis: An observational study. Arthritis Care Res (Hoboken). 2017 Feb; 69(2):209-15. doi: 10.1002/acr.22928White DK, Tudor-Locke C, Zhang Y, et al. Prospective change in daily walking over 2 years in older adults with or at risk of knee osteoarthritis: the MOST study. Osteoarthritis Cartilage. 2016 Feb;24(2):246-53. doi: 10.1016/j.joca.2015.08.004White DK, Tudor-Locke C, Zhang Y, et al. Prospective change in daily walking over 2 years in older adults with or at risk of knee osteoarthritis: the MOST study. Osteoarthritis Cartilage. 2016 Feb;24(2):246-53. doi: 10.1016/j.joca.2015.08.004Lee AC, Driban JB, Price LL, et al. Responsiveness and minimally important differences for 4 patient-reported outcomes measurement information system short forms: physical function, pain interference, depression, and anxiety in knee osteoarthritis. J Pain. 2017 Sep;18(9):1096-110. doi: 10.1016/j.jpain.2017.05.001Lee AC, Driban JB, Price LL, et al. Responsiveness and minimally important differences for 4 patient-reported outcomes measurement information system short forms: physical function, pain interference, depression, and anxiety in knee osteoarthritis. J Pain. 2017 Sep;18(9):1096-110. doi: 10.1016/j.jpain.2017.05.001Li H, George DM, Jaarsma RL, Mao X. Metabolic syndrome and components exacerbate osteoarthritis symptoms of pain, depressionand reduced knee function. Ann Transl Med. 2016 Apr;4(7):133. doi: 10.21037/atm.2016.03.48Li H, George DM, Jaarsma RL, Mao X. Metabolic syndrome and components exacerbate osteoarthritis symptoms of pain, depressionand reduced knee function. Ann Transl Med. 2016 Apr;4(7):133. doi: 10.21037/atm.2016.03.48Van der Esch M, Knoop J, van der Leeden M, et al. Clinical phenotypes in patients with knee osteoarthritis: a study in the Amsterdam osteoarthritis cohort. Osteoarthritis Cartilage. 2015 Apr; 23(4):544-9. doi: 10.1016/j.joca.2015.01.006Van der Esch M, Knoop J, van der Leeden M, et al. Clinical phenotypes in patients with knee osteoarthritis: a study in the Amsterdam osteoarthritis cohort. Osteoarthritis Cartilage. 2015 Apr; 23(4):544-9. doi: 10.1016/j.joca.2015.01.006Lincoln N, Moreton B, Turner K, Walsh D. The measurement of psychological constructs in people with osteoarthritis of the knee: a psychometric evaluation. Disabil Rehabil. 2017 Feb;39(4):37284. doi: 10.3109/09638288.2016.1146356Lincoln N, Moreton B, Turner K, Walsh D. The measurement of psychological constructs in people with osteoarthritis of the knee: a psychometric evaluation. Disabil Rehabil. 2017 Feb;39(4):37284. doi: 10.3109/09638288.2016.1146356Mesci N, Mesci E, Külcü DG. Association of neuropathic pain with ultrasonographic measurements of femoral cartilage thickness and clinical parameters in patients with knee osteoarthritis. J Phys Ther Sci. 2016 Aug;28(8):2190-5. doi: 10.1589/jpts.28.2190Mesci N, Mesci E, Külcü DG. Association of neuropathic pain with ultrasonographic measurements of femoral cartilage thickness and clinical parameters in patients with knee osteoarthritis. J Phys Ther Sci. 2016 Aug;28(8):2190-5. doi: 10.1589/jpts.28.2190Hochman JR, Davis AM, Elkayam J, et al. Neuropathic pain symptoms on the modified painDETECT correlate with signs of central sensitization in knee osteoarthritis. Osteoarthritis Cartilage. 2013 Sep;21(9):1236-42. doi: 10.1016/j.joca.2013.06.023Hochman JR, Davis AM, Elkayam J, et al. Neuropathic pain symptoms on the modified painDETECT correlate with signs of central sensitization in knee osteoarthritis. Osteoarthritis Cartilage. 2013 Sep;21(9):1236-42. doi: 10.1016/j.joca.2013.06.023Parmelee PA, Tighe CA, Dautovich ND. Sleep disturbance in osteoarthritis: linkages with pain, disability, and depressive symptoms. Arthritis Care Res (Hoboken). 2015 Mar;67(3):358-65. doi: 10.1002/acr.22459Parmelee PA, Tighe CA, Dautovich ND. Sleep disturbance in osteoarthritis: linkages with pain, disability, and depressive symptoms. Arthritis Care Res (Hoboken). 2015 Mar;67(3):358-65. doi: 10.1002/acr.22459Hawker GA, Gignac MA, Badley E, et al. A longitudinal study to explain the pain-depression link in older adults with osteoarthritis. Arthritis Care Res (Hoboken). 2011 Oct;63(10):1382-90.Hawker GA, Gignac MA, Badley E, et al. A longitudinal study to explain the pain-depression link in older adults with osteoarthritis. Arthritis Care Res (Hoboken). 2011 Oct;63(10):1382-90.Tang HJ, McCurry SM, Pike KC, et al. Differential predictors of nighttime and daytime sleep complaints in older adults with comorbid insomni and osteoarthritis pain. J Psychosom Res. 2017 Sep;100:22-28. doi: 10.1016/j.jpsychores.2017.06.020. Epub 2017 Jul 1.Tang HJ, McCurry SM, Pike KC, et al. Differential predictors of nighttime and daytime sleep complaints in older adults with comorbid insomni and osteoarthritis pain. J Psychosom Res. 2017 Sep;100:22-28. doi: 10.1016/j.jpsychores.2017.06.020. Epub 2017 Jul 1.Shimura Y, Kurosawa H, Sugawara Y, et al. The factors associated with pain severity in patients with knee osteoarthritis vary according to the radiographic disease severity: a cross-sectional study. Osteoarthritis Cartilage. 2013 Sep;21(9):1179-84. doi: 10.1016/j.joca.2013.05.014Shimura Y, Kurosawa H, Sugawara Y, et al. The factors associated with pain severity in patients with knee osteoarthritis vary according to the radiographic disease severity: a cross-sectional study. Osteoarthritis Cartilage. 2013 Sep;21(9):1179-84. doi: 10.1016/j.joca.2013.05.014Hawker GA, French MR, Waugh EJ, et al. The multidimensionality of sleep quality and its relationship to fatigue in older adults with painful osteoarthritis. Osteoarthritis Cartilage. 2010 Nov;18(11):1365-71. doi: 10.1016/j.joca.2010.08.002Hawker GA, French MR, Waugh EJ, et al. The multidimensionality of sleep quality and its relationship to fatigue in older adults with painful osteoarthritis. Osteoarthritis Cartilage. 2010 Nov;18(11):1365-71. doi: 10.1016/j.joca.2010.08.002Ahn H, Weaver M, Lyon D, et al. Depression and pain in asian and white americans with knee osteoarthritis. J Pain. 2017 Oct;18(10):1229-36. doi: 10.1016/j.jpain.2017.05.007Ahn H, Weaver M, Lyon D, et al. Depression and pain in asian and white americans with knee osteoarthritis. J Pain. 2017 Oct;18(10):1229-36. doi: 10.1016/j.jpain.2017.05.007Monaghan PG, Peloso PM, Everett SV, et al. Inadequate pain relief and large functional loss among patients with knee osteoarthritis: evidence from a prospective multinational longitudinal study of osteoarthritis real-world therapies. Rheumatology (Oxford). 2015 Feb;54(2):270-7. doi: 10.1093/rheumatology/keu332Monaghan PG, Peloso PM, Everett SV, et al. Inadequate pain relief and large functional loss among patients with knee osteoarthritis: evidence from a prospective multinational longitudinal study of osteoarthritis real-world therapies. Rheumatology (Oxford). 2015 Feb;54(2):270-7. doi: 10.1093/rheumatology/keu332Laires PA, Lains J, Miranda LC, et al. Inadequate pain relief among patients with primary knee osteoarthritis. Rev Bras Reumatol Engl Ed. 2017 May-Jun;57(3):229-37. doi: 10.1016/j.rbre.2016.11.005Laires PA, Lains J, Miranda LC, et al. Inadequate pain relief among patients with primary knee osteoarthritis. Rev Bras Reumatol Engl Ed. 2017 May-Jun;57(3):229-37. doi: 10.1016/j.rbre.2016.11.005Gandhi R, Zywiel MG, Mahomed NN, Perruccio AV. Depression and the overall burden of painful joints: An examination among individuals undergoing hip and knee replacement for osteoarthritis. Arthritis. 2015;2015:327161. doi: 10.1155/2015/327161Gandhi R, Zywiel MG, Mahomed NN, Perruccio AV. Depression and the overall burden of painful joints: An examination among individuals undergoing hip and knee replacement for osteoarthritis. Arthritis. 2015;2015:327161. doi: 10.1155/2015/327161Bierke S, Häner M, Petersen W. Influence of somatization and depressive symptoms on the course of pain within the first year after uncomplicated total knee replacement: a prospective study. Int Orthop. 2016 Jul;40(7):1353-60. doi: 10.1007/s00264-015-3105-zBierke S, Häner M, Petersen W. Influence of somatization and depressive symptoms on the course of pain within the first year after uncomplicated total knee replacement: a prospective study. Int Orthop. 2016 Jul;40(7):1353-60. doi: 10.1007/s00264-015-3105-zDhurve K, Scholes C, El-Tawil S, et al. Multifactorial analysis of dissatisfaction after primary total knee replacement. Knee. 2017 Aug;24(4):856-62. doi: 10.1016/j.knee.2017.04.005Dhurve K, Scholes C, El-Tawil S, et al. Multifactorial analysis of dissatisfaction after primary total knee replacement. Knee. 2017 Aug;24(4):856-62. doi: 10.1016/j.knee.2017.04.005Wong LY, Yiu RL, Chiu CK, et al. Prevalence of psychiatric morbidity in chinese subjects with knee osteoarthritis in a Hong Kong Orthopaedic Clinic. East Asian Arch Psychiatry. 2015 Dec;25(4):150-8.Wong LY, Yiu RL, Chiu CK, et al. Prevalence of psychiatric morbidity in chinese subjects with knee osteoarthritis in a Hong Kong Orthopaedic Clinic. East Asian Arch Psychiatry. 2015 Dec;25(4):150-8.Ali A, Sundberg M, Robertsson O, et al. Dissatisfied patients after total knee arthroplasty: a registry study involving 114 patients with 8-13 years of followup. Acta Orthop. 2014 Jun;85(3):229-33. doi: 10.3109/17453674.2014.916487Ali A, Sundberg M, Robertsson O, et al. Dissatisfied patients after total knee arthroplasty: a registry study involving 114 patients with 8-13 years of followup. Acta Orthop. 2014 Jun;85(3):229-33. doi: 10.3109/17453674.2014.916487Ali A, Lindstrand A, Sundberg M, Flivik G. Preoperative anxiety and depression correlate with dissatisfaction after total knee arthroplasty: A prospective longitudinal cohort study of 186 patients, with 4-year follow-up. J Arthroplasty. 2017 Mar;32(3):767-70. doi: 10.1016/j.arth.2016.08.033. Epub 2016 Sep 3.Ali A, Lindstrand A, Sundberg M, Flivik G. Preoperative anxiety and depression correlate with dissatisfaction after total knee arthroplasty: A prospective longitudinal cohort study of 186 patients, with 4-year follow-up. J Arthroplasty. 2017 Mar;32(3):767-70. doi: 10.1016/j.arth.2016.08.033. Epub 2016 Sep 3.Cho CH, Song KS, Hwang I, et al. Changes in psychological status and health-related quality of life following total shoulder arthroplasty. J Bone Joint Surg Am. 2017 Jun 21;99(12):1030-5. doi: 10.2106/JBJS.16.00954Cho CH, Song KS, Hwang I, et al. Changes in psychological status and health-related quality of life following total shoulder arthroplasty. J Bone Joint Surg Am. 2017 Jun 21;99(12):1030-5. doi: 10.2106/JBJS.16.00954Tuszynska-Bogucka W, Saran T, Jurkowska B, Dziaduch W. Psychosocial generalised resistance resources and clinical indicators of patients suffering from osteoarthritis at the Institute of Rural Health in Lublin, Poland. Ann Agric Environ Med. 2015;22(2):380-4. doi: 10.5604/12321966.1152098Tuszynska-Bogucka W, Saran T, Jurkowska B, Dziaduch W. Psychosocial generalised resistance resources and clinical indicators of patients suffering from osteoarthritis at the Institute of Rural Health in Lublin, Poland. Ann Agric Environ Med. 2015;22(2):380-4. doi: 10.5604/12321966.1152098Benz T, Angst F, Lehmann S, Aeschlimann A. Association of the sense of coherence with physical and psychosocial health in the rehabilitation of osteoarthritis of the hip and knee: a prospective cohort study. BMC Musculoskelet Disord. 2013 May 4;14:159. doi: 10.1186/1471-2474-14-159Benz T, Angst F, Lehmann S, Aeschlimann A. Association of the sense of coherence with physical and psychosocial health in the rehabilitation of osteoarthritis of the hip and knee: a prospective cohort study. BMC Musculoskelet Disord. 2013 May 4;14:159. doi: 10.1186/1471-2474-14-159Smink AJ, Dekker J, Vliet Vlieland TP, et al. Health care use of patients with osteoarthritis of the hip or knee after implementation of a stepped-care strategy: an observational study. Arthritis Care Res (Hoboken). 2014 Jun;66(6):817-27. doi: 10.1002/acr.22222Smink AJ, Dekker J, Vliet Vlieland TP, et al. Health care use of patients with osteoarthritis of the hip or knee after implementation of a stepped-care strategy: an observational study. Arthritis Care Res (Hoboken). 2014 Jun;66(6):817-27. doi: 10.1002/acr.22222MacKay C, Webster F, Venkataramanan V, et al. A prospective cohort study examining medical and social factors associated with engagement in life activities following total hip replacement. Osteoarthritis Cartilage. 2017 Jul;25(7):1032-9. doi: 10.1016/j.joca.2017.02.787MacKay C, Webster F, Venkataramanan V, et al. A prospective cohort study examining medical and social factors associated with engagement in life activities following total hip replacement. Osteoarthritis Cartilage. 2017 Jul;25(7):1032-9. doi: 10.1016/j.joca.2017.02.787Hochberg MC, Altman RD, April KT, et al. American College of Rheumatology 2012 recommendations for the use of nonpharmacologic and pharmacologic therapies in osteoarthritis of the hand, hip, and knee. Arthritis Care Res (Hoboken). 2012 Apr; 64(4):46574. doi: 10.1002/acr.21596. Review.Hochberg MC, Altman RD, April KT, et al. American College of Rheumatology 2012 recommendations for the use of nonpharmacologic and pharmacologic therapies in osteoarthritis of the hand, hip, and knee. Arthritis Care Res (Hoboken). 2012 Apr; 64(4):46574. doi: 10.1002/acr.21596. Review.Werner BC, Wong AC, Chang B, et al. Depression and patientreported outcomes following total shoulder arthroplasty. J Bone Joint Surg Am. 2017 Apr 19;99(8):688-95. doi: 10.2106/JBJS.16.00541Werner BC, Wong AC, Chang B, et al. Depression and patientreported outcomes following total shoulder arthroplasty. J Bone Joint Surg Am. 2017 Apr 19;99(8):688-95. doi: 10.2106/JBJS.16.00541Liu R, Damman W, Beaart-van de Voorde L, et al. Aesthetic dissatisfaction in patients with hand osteoarthritis and its impact on daily life. Scand J Rheumatol. 2016;45(3):219-23. doi: 10.3109/03009742.2015.1079731Liu R, Damman W, Beaart-van de Voorde L, et al. Aesthetic dissatisfaction in patients with hand osteoarthritis and its impact on daily life. Scand J Rheumatol. 2016;45(3):219-23. doi: 10.3109/03009742.2015.1079731Lopez DL, Fernandez JM, Iglesias ME, et al. Influence of depression in a sample of people with hallux valgus. Int J Ment Health Nurs. 2016 Dec;25(6):574-8. doi: 10.1111/inm.12196Lopez DL, Fernandez JM, Iglesias ME, et al. Influence of depression in a sample of people with hallux valgus. Int J Ment Health Nurs. 2016 Dec;25(6):574-8. doi: 10.1111/inm.12196Iyengar RL, Gandhi S, Aneja A, et al. NSAIDs are associated with lower depression scores in patients with osteoarthritis. Am J Med. 2013 Nov;126(11):1017.e11-8. doi: 10.1016/j.amjmed.2013.02.037Iyengar RL, Gandhi S, Aneja A, et al. NSAIDs are associated with lower depression scores in patients with osteoarthritis. Am J Med. 2013 Nov;126(11):1017.e11-8. doi: 10.1016/j.amjmed.2013.02.037Kaczmarek M, Moneta P, Zytkowski A, Niedzielski J. Symptoms of depression in elderly patients with osteoarticular diseases undergoing hospital rehabilitation. Ortop Traumatol Rehabil. 2014 NovDec;16(6):645-60. doi: 10.5604/15093492.1135126Kaczmarek M, Moneta P, Zytkowski A, Niedzielski J. Symptoms of depression in elderly patients with osteoarticular diseases undergoing hospital rehabilitation. Ortop Traumatol Rehabil. 2014 NovDec;16(6):645-60. doi: 10.5604/15093492.1135126Kelley GA, Kelley KS. Effects of exercise on depressive symptoms in adults with arthritis and other rheumatic disease: a systematic review of meta-analyses. BMC Musculoskelet Disord. 2014 Apr 7;15:121. doi: 10.1186/1471-2474-15-121. Review.Kelley GA, Kelley KS. Effects of exercise on depressive symptoms in adults with arthritis and other rheumatic disease: a systematic review of meta-analyses. BMC Musculoskelet Disord. 2014 Apr 7;15:121. doi: 10.1186/1471-2474-15-121. Review.Kelley GA, Kelley KS. Exercise reduces depressive symptoms in adults with arthritis: Evidential value. World J Rheumatol. 2016 Jul 12;6(2):23-9. doi: 10.5499/wjr.v6.i2.23Kelley GA, Kelley KS. Exercise reduces depressive symptoms in adults with arthritis: Evidential value. World J Rheumatol. 2016 Jul 12;6(2):23-9. doi: 10.5499/wjr.v6.i2.23Marszalek J, Price LL, Harvey WF, et al. Outcome expectations and osteoarthritis: perceived benefits of exercise are associated with self-efficacy and depression. Arthritis Care Res (Hoboken). 2017 Apr;69(4):491-8. doi: 10.1002/acr.22969Marszalek J, Price LL, Harvey WF, et al. Outcome expectations and osteoarthritis: perceived benefits of exercise are associated with self-efficacy and depression. Arthritis Care Res (Hoboken). 2017 Apr;69(4):491-8. doi: 10.1002/acr.22969Geneen LJ, Moore RA, Clarke C, et al. Physical activity and exercise for chronic pain in adults: an overview of Cochrane Reviews. Cochrane Database Syst Rev. 2017 Apr 24;4:CD011279. doi: 10.1002/14651858. CD011279.pub3. Review.Geneen LJ, Moore RA, Clarke C, et al. Physical activity and exercise for chronic pain in adults: an overview of Cochrane Reviews. Cochrane Database Syst Rev. 2017 Apr 24;4:CD011279. doi: 10.1002/14651858. CD011279.pub3. Review.Sahin HG, Kunduracilar Z, Sönmezer E, et al. Effects of two different aquatic exercises training on cardiopulmonary endurance and anxiety & depression scores with knee osteoarthritis patients. Med Sci Sports Exerc. 2016 May;48(5 Suppl 1):589. doi: 10.1249/01.mss.0000486768.88623.cdSahin HG, Kunduracilar Z, Sönmezer E, et al. Effects of two different aquatic exercises training on cardiopulmonary endurance and anxiety & depression scores with knee osteoarthritis patients. Med Sci Sports Exerc. 2016 May;48(5 Suppl 1):589. doi: 10.1249/01.mss.0000486768.88623.cdGlickman-Simon R, Pettit J. Viscum album (mistletoe) for pancreatic cancer, electromagnetic field therapy for osteoarthritis, homeopathy for multidrug-resistant tuberculosis, vitamin D for depression, acupuncture for insomnia. Explore (NY). 2015 MayJun;11(3):231-5. doi: 10.1016/j.explore.2015.02.013Glickman-Simon R, Pettit J. Viscum album (mistletoe) for pancreatic cancer, electromagnetic field therapy for osteoarthritis, homeopathy for multidrug-resistant tuberculosis, vitamin D for depression, acupuncture for insomnia. Explore (NY). 2015 MayJun;11(3):231-5. doi: 10.1016/j.explore.2015.02.013Glickman-Simon R, Schneider C. Homeopathy for depression, music for postoperative recovery, red yeast rice for high cholesterol, acupuncture for seasonal allergic rhinitis, and ginger for osteoarthritis. Explore (NY). 2016 Jul-Aug;12(4):287-91. doi: 10.1016/j.explore.2016.04.015Glickman-Simon R, Schneider C. Homeopathy for depression, music for postoperative recovery, red yeast rice for high cholesterol, acupuncture for seasonal allergic rhinitis, and ginger for osteoarthritis. Explore (NY). 2016 Jul-Aug;12(4):287-91. doi: 10.1016/j.explore.2016.04.015MacPherson H, Vickers A, Bland M, et al. Acupuncture for chronic pain and depression in primary care: a programme of research. Southampton (UK): NIHR Journals Library; 2017 Jan. Programme Grants for Applied Research.MacPherson H, Vickers A, Bland M, et al. Acupuncture for chronic pain and depression in primary care: a programme of research. Southampton (UK): NIHR Journals Library; 2017 Jan. Programme Grants for Applied Research.Veronese N, Stubbs B, Noale M, et al. Adherence to the Mediterranean diet is associated with better quality of life: data from the Osteoarthritis Initiative. Am J Clin Nutr. 2016 Nov;104(5):1403-9. doi: 10.3945/ajcn.116.136390Veronese N, Stubbs B, Noale M, et al. Adherence to the Mediterranean diet is associated with better quality of life: data from the Osteoarthritis Initiative. Am J Clin Nutr. 2016 Nov;104(5):1403-9. doi: 10.3945/ajcn.116.136390Agarwal P, Pan X, Sambamoorthi U. Depression treatment patterns among individuals with osteoarthritis: a cross sectional study. BMC Psychiatry. 2013 Apr 22;13:121. doi: 10.1186/1471244X-13-121Agarwal P, Pan X, Sambamoorthi U. Depression treatment patterns among individuals with osteoarthritis: a cross sectional study. BMC Psychiatry. 2013 Apr 22;13:121. doi: 10.1186/1471244X-13-121Myers J, Wielage RC, Han B, et al. The efficacy of duloxetine, non-steroidal anti-inflammatory drugs, and opioids in osteoarthritis: a systematic literature review and meta-analysis. BMC Musculoskelet Disord. 2014 Mar 11;15:76. doi: 10.1186/1471-2474-15-76Myers J, Wielage RC, Han B, et al. The efficacy of duloxetine, non-steroidal anti-inflammatory drugs, and opioids in osteoarthritis: a systematic literature review and meta-analysis. BMC Musculoskelet Disord. 2014 Mar 11;15:76. doi: 10.1186/1471-2474-15-76Cruz-Almeida Y, King CD, Goodin BR, et al. Psychological profiles and pain characteristics of older adults with knee osteoarthritis. Arthritis Care Res (Hoboken). 2013 Nov;65(11):1786-94.Cruz-Almeida Y, King CD, Goodin BR, et al. Psychological profiles and pain characteristics of older adults with knee osteoarthritis. Arthritis Care Res (Hoboken). 2013 Nov;65(11):1786-94.Lo-Ciganic WH, Floden L, Lee JK, et al. Analgesic use and risk of recurrent falls in participants with or at risk of knee osteoarthritis: data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2017 Sep;25(9):1390-8. doi: 10.1016/j.joca.2017.03.017Lo-Ciganic WH, Floden L, Lee JK, et al. Analgesic use and risk of recurrent falls in participants with or at risk of knee osteoarthritis: data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2017 Sep;25(9):1390-8. doi: 10.1016/j.joca.2017.03.017Davis MC, Thummala K, Zautra AJ. Stress-related clinical pain and mood in women with chronic pain: moderating effects of depression and positive mood induction. Ann Behav Med. 2014 Aug;48(1):61-70. doi: 10.1007/s12160-013-9583-6Davis MC, Thummala K, Zautra AJ. Stress-related clinical pain and mood in women with chronic pain: moderating effects of depression and positive mood induction. Ann Behav Med. 2014 Aug;48(1):61-70. doi: 10.1007/s12160-013-9583-6Regier NG, Parmelee PA. The stability of coping strategies in older adults with osteoarthritis and the ability of these strategies to predict changes in depression, disability, and pain. Aging Ment Health. 2015;19(12):1113-22. doi: 10.1080/13607863.2014.1003286Regier NG, Parmelee PA. The stability of coping strategies in older adults with osteoarthritis and the ability of these strategies to predict changes in depression, disability, and pain. Aging Ment Health. 2015;19(12):1113-22. doi: 10.1080/13607863.2014.1003286Boot CR, de Kruif AT, Shaw WS, et al. Factors important for work participation among older workers with depression, cardiovascular disease, and osteoarthritis: A mixed method study. J Occup Rehabil. 2016 Jun;26(2):160-72. doi: 10.1007/s10926-015-9597-yBoot CR, de Kruif AT, Shaw WS, et al. Factors important for work participation among older workers with depression, cardiovascular disease, and osteoarthritis: A mixed method study. J Occup Rehabil. 2016 Jun;26(2):160-72. doi: 10.1007/s10926-015-9597-yMesci E, Icagasioglu A, Mesci N, Turgut ST. Relation of physical activity level with quality of life, sleep and depression in patients with knee osteoarthritis. North Clin Istanb. 2015 Dec 25;2(3):21521. doi: 10.14744/nci.2015.95867Mesci E, Icagasioglu A, Mesci N, Turgut ST. Relation of physical activity level with quality of life, sleep and depression in patients with knee osteoarthritis. North Clin Istanb. 2015 Dec 25;2(3):21521. doi: 10.14744/nci.2015.95867

The authors declare that there are no conflicts of interest present.