rspНаучно-практическая ревматологияRheumatology Science and Practice1995-44841995-4492IMA-PRESS, LLC10.14412/1995-4484-2018-405-415rsp-2584Research ArticleМЕЖДУНАРОДНЫЕ И РОССИЙСКИЕ РЕКОМЕНДАЦИИ ПО ЛЕЧЕНИЮ РЕВМАТИЧЕСКИХ ЗАБОЛЕВАНИЙINTERNATIONAL AND RUSSIAN GUIDELINES FOR THE TREATMENT OF RHEUMATIC DISEASESСовременные международные рекомендации по диагностике и лечению системной красной волчанки с ювенильным дебютомCURRENT INTERNATIONAL GUIDELINES FOR THE DIAGNOSIS AND TREATMENT OF JUVENILE-ONSET SYSTEMIC LUPUS ERYTHEMATOSUSКаледаМ. И.KaledaM. I.kaleda-mi@yandex.ruНикишинаИ. П.NikishinaI. P.ФГБНУ «Научноисследовательский институт ревматологии им. В.А. Насоновой», МоскваРоссияV.A. Nasonova Research Institute of Rheumatology, MoscowRussian Federation201808092018564405415Copyright © Каледа М.И., Никишина И.П., 20182018Каледа М.И., Никишина И.П.Kaleda M.I., Nikishina I.P.This work is licensed under a Creative Commons Attribution 4.0 License.https://rsp.mediar-press.net/rsp/article/view/2584

Системная красная волчанка (СКВ) с дебютом в детском и подростковом возрасте представляет существенную проблему в практике педиатров и ревматологов ввиду диагностических сложностей, особенностей течения и большей вероятности неблагоприятного прогноза. До 20% больных СКВ заболевают в возрасте младше 18 лет. Только у 13% пациентов с ювенильным дебютом во взрослом состоянии имеется безмедикаментозная ремиссия при более низком, чем в популяционном контроле, качестве жизни. Статья посвящена обсуждению последних международных рекомендаций по диагностике, мониторингу и лечению СКВ у детей и подростков, опубликованных в 2017 г., с комментариями, основанными на данных литературы и на практическом опыте ведения подобных пациентов.

Systemic lupus erythematosus (SLE) with its onset in childhood or adolescence is a significant problem in the practice of pediatricians and rheumatologists due to diagnostic difficulties, clinical features, and the greater likelihood of unfavorable prognosis. About 20% of SLE patients fall ill at the age of 18 years. Only 13% of patients with juvenile-onset SLE have a drug-free remission in adulthood and have a lower quality of life than population controls. The paper discusses the latest international guidelines for the diagnosis, monitoring, and treatment of SLE in children and adolescents, which were published in 2017, with comments based on the data available in the literature and on practical experiences in managing these patients.

 

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The authors declare that there are no conflicts of interest present.