rspНаучно-практическая ревматологияRheumatology Science and Practice1995-44841995-4492IMA-PRESS, LLC10.14412/1995-4484-2018-603-612rsp-2625Research ArticleПРОГРАММА НЕПРЕРЫВНОГО ПОСЛЕДИПЛОМНОГО ОБРАЗОВАНИЯ ВРАЧЕЙPOSTGRADUATE PROGRAM OF CONTINUING MEDICAL EDUCATIONРевматические проявления сахарного диабетаRHEUMATIC MANIFESTATIONS OF DIABETES MELLITUSКондратьеваЛ. В.KondratyevaL. V.

старший научный сотрудник лаборатории системных ревматических заболеваний, канд. мед. наук

115522, Москва, Каширское шоссе, 34А

34A, Kashirskoe Shosse, Moscow 115522

kondratyeva.liubov@yandex.ruПопковаТ. В.PopkovaT. V.

зав. лабораторией системных ревматических заболеваний, докт. мед. наук

115522, Москва, Каширское шоссе, 34А

34A, Kashirskoe Shosse, Moscow 115522

ФГБНУ "Научно-исследовательский институт ревматологии им. В.А. Насоновой"РоссияV.A. Nasonova Research Institute of RheumatologyRussian Federation201808112018565603612Copyright © Кондратьева Л.В., Попкова Т.В., 20182018Кондратьева Л.В., Попкова Т.В.Kondratyeva L.V., Popkova T.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://rsp.mediar-press.net/rsp/article/view/2625

В последние десятилетия наблюдается неуклонный рост распространенности сахарного диабета (СД) во всем мире, в том числе и в России. Большое внимание при СД традиционно уделяют микро- и макрососудистым осложнениям, однако при длительном и/или тяжелом течении СД возможно вовлечение и других органов, в том числе скелетно-мышечной системы и кожи. Поражение этих тканей при СД в большей степени объясняют избыточным образованием конечных продуктов гликирования. В статье рассмотрены основные ревматические проявления СД: синдром ограничения подвижности суставов, хироартропатия, контрактура Дюпюитрена, «щелкающий палец», адгезивный капсулит плечевого сустава, поражение ротаторной манжеты плеча, синдром карпального канала, нейроостеоартропатия Шарко, остеопороз, инфаркт мышцы, диабетическая склередема. Обсуждены вопросы патогенеза, диагностики и возможные методы терапии.

In recent decades, there has been a steady increase in the prevalence of diabetes mellitus (DM) worldwide, including Russia. Much attention has been customarily focused on micro- and macrovascular complications in DM; however, in its long and/or severe course, the complications may involve other organs, including the musculoskeletal system and skin. The involvement of these tissues in DM is largely explained by excessive production of advanced glycation end products. The paper considers the main rheumatic manifestations of DM: limited joint mobility syndrome, cheiroarthopathy, Dupuytren's contracture, trigger finger, adhesive capsulitis of the shoulder joint, rotator cuff injury, carpal tunnel syndrome, Charcot neuro-osteoarthropathy, osteoporosis, muscle infarction, and diabetic scleredema. The pathogenesis and diagnosis of DM and its possible therapy options are discussed.

сахарный диабетконечные продукты гликированиясиндром ограничения подвижности суставовхироартропатияконтрактура Дюпюитрена«щелкающий палец»адгезивный капсулитротатор- ная манжета плечасиндром карпального каналанейроостеоартропатия Шаркоостеопорозинфаркт мыш- цыдиабетическая склередемаdiabetes mellitusadvanced glycation end productslimited joint mobility syndromecheiroarthopathyDupuytren's contracturetrigger fingeradhesive capsulitisrotator cuff injurycarpal tunnel syndromeCharcot neuro-osteoarthropathyosteoporosismuscle infarctiondiabetic scleredemaReferencesДедов ИИ, Шестакова МВ, Майоров АЮ, редакторы. Алгоритмы специализированной медицинской помощи больным сахарным диабетом. 8-й выпуск. Сахарный диабет. 2017;20(1S):1-121 [Dedov II, Shestakova MV, Mayorov AYu, eds. Standards of specialized diabetes care. 8th ed. Sakharnyi Diabet = Diabetes Mellitus. 2017;20(1S):1-121 (In Russ.)]. doi: 10.14341/DM20171S8Дедов ИИ, Шестакова МВ, Майоров АЮ, редакторы. 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The authors declare that there are no conflicts of interest present.