rspНаучно-практическая ревматологияRheumatology Science and Practice1995-44841995-4492IMA-PRESS, LLC10.14412/1995-4484-2018-760-766rsp-2654Research ArticleФОРУМ МОЛОДЫХ УЧЕНЫХYOUNG SCIENTISTS FORUMПрофилактика приступов артрита при назначении уратснижающей терапии у больных подагройPrevention of arthritis attacks in the use of urate-lowering therapy in patients with goutЧикинаМ. Н.ChikinaM. N.

м.н.с. лаборатории микрокристаллических артритов (научный руководитель –к.м.н. М.С. Елисеев).

115522 Москва, Каширское шоссе, 34А.

34A, Kashirskoe Shosse, Moscow, 115522.

Maria.sorokvasha@yandex.ruФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой».РоссияV.A. Nasonova Research Institute of Rheumatology.Russian Federation201821012019566760766Copyright © Чикина М.Н., 20192019Чикина М.Н.Chikina M.N.This work is licensed under a Creative Commons Attribution 4.0 License.https://rsp.mediar-press.net/rsp/article/view/2654

В течение первых месяцев после инициации уратснижающей терапии у больных подагрой риск развития обострения артрита существенно возрастает, зачастую приводя к отказу больных от данного лечения. Основным способом избежать этого риска является превентивное назначение колхицина, нестероидных противовоспалительных препаратов или глюкокортикоидов. Подобная профилактика приступов артрита оговорена в последних версиях многих национальных и международных рекомендаций, тем не менее на практике данная тактика используется редко. В обзоре представлены наиболее значимые исследования, посвященные данной проблеме.

During the first months after initiation of urate-lowering therapy in patients with gout, the risk of exacerbating arthritis substantially increases, frequently causing them to refuse this treatment. The main way to avoid this risk is the preventive administration of colchicine, nonsteroidal anti-inflammatory drugs, or glucocorticoids. This prevention of arthritis attacks is stipulated in the latest versions of many national and international guidelines; nevertheless, this tactic is rarely used in practice. The review presents the most significant studies on this problem.

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The authors declare that there are no conflicts of interest present.