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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rsp</journal-id><journal-title-group><journal-title xml:lang="ru">Научно-практическая ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Rheumatology Science and Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-4484</issn><issn pub-type="epub">1995-4492</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1995-4484-2018-767-776</article-id><article-id custom-type="elpub" pub-id-type="custom">rsp-2655</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group></article-categories><title-group><article-title>Болезнь Бехчета: поражение кишечника</article-title><trans-title-group xml:lang="en"><trans-title>Behсet's disease: intestinal damage</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Голоева</surname><given-names>Р. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Goloeva</surname><given-names>R. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522 Москва, Каширское шоссе, 34А.</p></bio><bio xml:lang="en"><p>34A, Kashirskoe Shosse, Moscow 115522.</p></bio><email xlink:type="simple">regina_goloeva@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алекберова</surname><given-names>З. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Alekberova</surname><given-names>Z. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522 Москва, Каширское шоссе, 34А.</p></bio><bio xml:lang="en"><p>34A, Kashirskoe Shosse, Moscow 115522.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой».</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.A. Nasonova Research Institute of Rheumatology.</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>21</day><month>01</month><year>2019</year></pub-date><volume>56</volume><issue>6</issue><fpage>767</fpage><lpage>776</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Голоева Р.Г., Алекберова З.С., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Голоева Р.Г., Алекберова З.С.</copyright-holder><copyright-holder xml:lang="en">Goloeva R.G., Alekberova Z.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://rsp.mediar-press.net/rsp/article/view/2655">https://rsp.mediar-press.net/rsp/article/view/2655</self-uri><abstract><p>Болезнь Бехчета (ББ) – системный васкулит неизвестной этиологии, характеризуется рецидивами язвенного процесса в ротовой полости и на гениталиях, поражением глаз, суставов, сосудов и других органов. При ББ именно органная патология определяет тяжесть и прогноз болезни. Наиболее сложным и наименее изученным вариантом таких изменений является поражение кишечника. Его верификация при ББ затруднена многообразием клинических проявлений, их схожестью с воспалительными заболеваниями кишечника, отсутствием достаточно информативных лабораторных тестов, патогномоничных эндоскопических и гистологических признаков. Поражение кишечника при ББ (ПКББ) способно привести к серьезным осложнениям (массивное кровотечение, перфорация кишки и образование свища), что может не только существенно снизить качество жизни пациента, но и стать причиной летального исхода. Лечение ПКББ не стандартизовано, в основном носит эмпирический характер и проводится курсами. Цель терапии состоит в том, чтобы добиться клинической ремиссии, заживления язв кишечника, уменьшить частоту рецидивов и предотвратить хирургическое вмешательство. Кумулятивная частота хирургических вмешательств следующая: 20% из них выполняется за первый год, 27–33% – в течение 5 лет и 31–46% – в течение 10 лет после постановки диагноза ПКББ. Одной из проблем хирургического лечения пациентов с ПКББ является риск рецидива заболевания, нередко требующий повторной операции. Так, 2- и 5-летние показатели рецидивов после операции составили 29,2 и 47,2% соответственно. Факторами плохого прогноза являются молодой возраст (&lt;40 лет), высокая активность заболевания на момент установления диагноза, обнаружение при колоноскопии «кратерообразных» или глубоких язв, высокий уровень С-реактивного белка и лапаротомия в анамнезе.</p></abstract><trans-abstract xml:lang="en"><p>Behсet's disease (BD) is a systemic vasculitis of an unknown etiology characterized by repeated oral and genital ulcerations and involvement of the eyes, joints, blood vessels, and other organs. In BD, it is the organ pathology that determines the severity and prognosis of the disease. The most difficult and least studied version of such changes is intestinal damage. Its verification in BD is complicated by a variety of clinical manifestations, their similarity with inflammatory bowel diseases, the lack of sufficiently informative laboratory tests, and pathognomonic endoscopic and histological signs. Intestinal BD (IBD) can result in serious complications (severe bleeding, intestinal perforation, and fistula formation), which may not only considerably reduce the quality of life of the patient, but also cause his death. Treatment for IBD is not standardized; it is mainly empirical and is performed as cycles. The goal of its therapy is to achieve clinical remission, to heal intestinal ulcers, to reduce recurrence rates, and to prevent surgery. The cumulative frequency of surgical interventions is as follows: 20% of them are performed in the first year, 27–33% within 5 years, and 31–46% within 10 years after IBD diagnosis. One of the problems in the surgical treatment of patients with IBD is the risk of a recurrence that often requires repeat surgery. Thus, 2- and 5-year postoperative recurrence rates were 29.2 and 47.2%, respectively. The poor prognostic factors are young age (&lt;40 years), high disease activity at the time of diagnosis, detection of crateriform or deep ulcers at colonoscopy, high C-reactive protein level, and history of laparotomy.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>болезнь Бехчета</kwd><kwd>язвы кишечника</kwd><kwd>перфорация подвздошной кишки</kwd><kwd>колонскопия</kwd><kwd>капсульная колоноскопия</kwd><kwd>ультразвуковое исследование кишечника</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Behсet's disease</kwd><kwd>intestinal ulcers</kwd><kwd>ileal perforation</kwd><kwd>colonoscopy</kwd><kwd>capsule colonoscopy</kwd><kwd>intestinal ultrasound examination</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Алекберова ЗС. Болезнь Бехчета. Москва; 2007. 90 с. [Alekberova ZS. Bolezn' Bekhcheta [Behcet's disease]. Moscow; 2007. 90 p. 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