rspНаучно-практическая ревматологияRheumatology Science and Practice1995-44841995-4492IMA-PRESS, LLC10.14412/1995-4484-2019-38-45rsp-2672Research ArticleОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯORIGINAL RESEARCHРусский перевод и валидация SarQoL® – опросника качества жизни для пациентов с саркопениейRussian translation and validation of SarQoL® – quality of life questionnaire for patients with sarcopeniaСафоноваЮ. А.SafonovaYu. A.

191015, Санкт-Петербург, ул. Кирочная, 41;

190068, Санкт-Петербург, Большая Подьяческая ул., 30

41, Kirochnaya St., St. Petersburg 191015;

30, Bol'shaya Pod'yacheskaya St., St. Petersburg 190068

jula_safonova@mail.ruЛеснякО. М.LesnyakO. M.

191015, Санкт-Петербург, ул. Кирочная, 41;

190068, Санкт-Петербург, Большая Подьяческая ул., 30

41, Kirochnaya St., St. Petersburg 191015;

30, Bol'shaya Pod'yacheskaya St., St. Petersburg 190068

БарановаИ. А.BaranovaI. A.

117997, г. Москва, ул. Островитянова, 1;

105077, Москва, 11-я Парковая ул., 32

1, Ostrovityanova St., Moscow 117997;

32, 11th Parkovaya St., Moscow 105077

СулеймановаА. К.SuleimanovaA. K.

117997, г. Москва, ул. Островитянова, 1;

105077, Москва, 11-я Парковая ул., 32

1, Ostrovityanova St., Moscow 117997;

32, 11th Parkovaya St., Moscow 105077

ЗоткинЕ. Г.ZotkinE. G.ФГБОУ ВО «Северо-Западный государственный медицинский университет им. И.И. Мечникова» Минздрава России; СПб ГБУЗ «Клиническая ревматологическая больница №25»РоссияI.I. Mechnikov North-Western State Medical University, Ministry of Health of Russia; SaintPetersburg Clinical Rheumatological Hospital №25Russian FederationФГБОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России; ГБУЗ «Городская клиническая больница им. Д.Д. Плетнева Департамента здравоохранения г. Москвы»РоссияN.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia; D.D. Pletnev City Clinical Hospital, Moscow Department of HealthRussian FederationФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»РоссияV.A. Nasonova Research Institute of RheumatologyRussian Federation2019190320195713845Copyright © Сафонова Ю.А., Лесняк О.М., Баранова И.А., Сулейманова А.К., Зоткин Е.Г., 20192019Сафонова Ю.А., Лесняк О.М., Баранова И.А., Сулейманова А.К., Зоткин Е.Г.Safonova Y.A., Lesnyak O.M., Baranova I.A., Suleimanova A.K., Zotkin E.G.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://rsp.mediar-press.net/rsp/article/view/2672

Цель – проведение языковой адаптации и валидации на российской выборке специального опросника SarQoL, предназначенного для оценки качества жизни людей пожилого возраста с саркопенией. Материал и методы. Включено 100 пациентов старше 65 лет, средний возраст 74,0±6,5 года, наблюдавшихся амбулаторно, из них 50 участников с диагностированной саркопенией и 50 участников без саркопении. Диагноз саркопении устанавливался на основании критериев, разработанных Европейской рабочей группой изучения саркопении (EWGSOP, 2010). Процедура валидации проходила в соответствии с протоколом. Результаты и обсуждение. Выявлено значительное снижение общего показателя качества жизни по опроснику SarQoL у пациентов с саркопенией по сравнению с контрольной группой без саркопении (50,65±14,23 и 75,10±14,46 соответственно; р<0,001), высокая внутренняя согласованность опросника SarQoL (коэффициент á Кронбаха 0,924). Установлена значимая положительная корреляция доменов с общим показателем SarQoL в диапазоне от r=0,37, р=0,0083 до r=0,92, р<0,001. Выявлены умеренные корреляционные связи между SarQoL и некоторыми доменами SF-36 и опросника EQ-5D. Обнаружена высокая внутренняя согласованность (ICC) 0,935 (95% ДИ 0,91–0,96). Заключение. Русскоязычная версия опросника SarQoL является валидной, последовательной и надежной и может быть использована для оценки качества жизни у пациентов старшего возраста с саркопенией.

The aim is to carry out language adaptation and validation on the Russian sample of a special SarQoL questionnaire, designed to assess the quality of life of elderly people with sarcopenia. Material and methods. 100 patients over 65 years, mean age 74.0±6.5 years, observed on an outpatient basis were included. 50 from them had sarcopenia and 50 participants were without it. The diagnosis of sarcopenia was based on criteria developed by the European working group on sarcopenia (EWGSOP, 2010). The validation procedure was carried out in accordance with the Protocol. Results and discussion. There was a significant decrease in the overall quality of life according to SarQoL questionnaire in patients with sarcopenia compared with the control group without sarcopenia (50.65±14.23 and 75.10±14.46, respectively; p<0.001). High internal consistency of the SarQoL (Cronbach's á coefficient 0.924) was revealed. A significant positive correlation of domains with the overall SarQoL index in the range from r=0.37, p=0.0083 to r=0.92, p<0.001 was established. Moderate correlations of SarQoL with some domains SF-36 and the EQ-5D questionnaires were revealed. High internal consistency (ICC) of 0.935 (95% CI 0.91-0.96) was found. Conclusion. The Russian version of the SarQoL questionnaire is valid, consistent and reliable and can be used to assess the quality of life in older patients with sarcopenia.

саркопенияпожилой возрасткачество жизниsarcopeniaelderly agequality of lifeReferencesRosenberg I. Summary comments: epidemiological and methodological problems in determining nutritional status of older persons. Am J Clin Nutr. 1989;50(5):1231-3. doi: 10.1093/ajcn/50.5.1231Rosenberg I. Summary comments: epidemiological and methodological problems in determining nutritional status of older persons. Am J Clin Nutr. 1989;50(5):1231-3. doi: 10.1093/ajcn/50.5.1231Woods JL, Iuliano-Burns S, King SJ, et al. Poor physical function in elderly women in low-level aged care is related to muscle strength rather than to measures of sarcopenia. Clin Intervent Aging. 2011;6:67-76. doi: 10.2147/cia.s16979Woods JL, Iuliano-Burns S, King SJ, et al. Poor physical function in elderly women in low-level aged care is related to muscle strength rather than to measures of sarcopenia. Clin Intervent Aging. 2011;6:67-76. doi: 10.2147/cia.s16979Cooper C, Dere W, Evans W, et al. Frailty and sarcopenia: definitions and outcome parameters. Osteoporos Int. 2012;23(7):1839-48. doi: 10.1007/s00198-012-1913-1Cooper C, Dere W, Evans W, et al. Frailty and sarcopenia: definitions and outcome parameters. Osteoporos Int. 2012;23(7):1839-48. doi: 10.1007/s00198-012-1913-1Baumgartner RN, Koehler KM, Gallagher D, et al. Epidemiology of sarcopenia among the elderly in New Mexico. Am J Epidemiol. 1998;147(8):755-63. doi: 10.1093/oxfordjournals.aje.a009520Baumgartner RN, Koehler KM, Gallagher D, et al. Epidemiology of sarcopenia among the elderly in New Mexico. Am J Epidemiol. 1998;147(8):755-63. doi: 10.1093/oxfordjournals.aje.a009520Beaudart C, Rizzoli R, Bruyere O, et al. Sarcopenia: burden and challenges for Public Health. Arch Pub Health. 2014;72:45. doi: 10.1186/2049-3258-72-45Beaudart C, Rizzoli R, Bruyere O, et al. Sarcopenia: burden and challenges for Public Health. Arch Pub Health. 2014;72:45. doi: 10.1186/2049-3258-72-45Lauretani F, Russo CR, Bandinelli S, et al. Age-associated changes in skeletal muscles and their effect on mobility: an operational diagnosis of sarcopenia. J Appl Physiol. 2003;95(5):1851-60. doi: 10.1152/japplphysiol.00246.2003Lauretani F, Russo CR, Bandinelli S, et al. Age-associated changes in skeletal muscles and their effect on mobility: an operational diagnosis of sarcopenia. J Appl Physiol. 2003;95(5):1851-60. doi: 10.1152/japplphysiol.00246.2003Janssen I. Influence of sarcopenia on the development of physical disability: the Cardiovascular Health Study. J Am Geriatr Soc. 2006;54(1):56-62. doi: 10.1111/j.1532-5415.2005.00540.xJanssen I. Influence of sarcopenia on the development of physical disability: the Cardiovascular Health Study. J Am Geriatr Soc. 2006;54(1):56-62. doi: 10.1111/j.1532-5415.2005.00540.xVisser M, Goodpaster BH, Kritchevsky SB, et al. Muscle mass, muscle strength, and muscle fat infiltration as predictors of incident mobility limitations in well-functioning older persons. J Gerontol A Biol Sci Med Sci. 2005;60(3):324-33. doi: 10.1093/gerona/60.3.324Visser M, Goodpaster BH, Kritchevsky SB, et al. Muscle mass, muscle strength, and muscle fat infiltration as predictors of incident mobility limitations in well-functioning older persons. J Gerontol A Biol Sci Med Sci. 2005;60(3):324-33. doi: 10.1093/gerona/60.3.324Lang T, Streeper T, Cawthon P, et al. Sarcopenia: etiology, clinical consequences, intervention, and assessment. Osteoporos Int. 2010;21(4):543-59. doi: 10.1007/s00198-009-1059-yLang T, Streeper T, Cawthon P, et al. Sarcopenia: etiology, clinical consequences, intervention, and assessment. Osteoporos Int. 2010;21(4):543-59. doi: 10.1007/s00198-009-1059-yRizzoli R, Reginster JY, Arnal JF, et al. Quality of life in sarcopenia and frailty. Calcif Tissue Int. 2013;93(2):101-20. doi: 10.1007/s00223-013-9758-yRizzoli R, Reginster JY, Arnal JF, et al. Quality of life in sarcopenia and frailty. Calcif Tissue Int. 2013;93(2):101-20. doi: 10.1007/s00223-013-9758-ySayer AA, Dennison EM, Syddall HE, et al. Type 2 diabetes, muscle strength, and impaired physical function: the tip of the iceberg? Diabetes Care. 2005;28(10):2541-2. doi: 10.2337/diacare.28.10.2541Sayer AA, Dennison EM, Syddall HE, et al. Type 2 diabetes, muscle strength, and impaired physical function: the tip of the iceberg? Diabetes Care. 2005;28(10):2541-2. doi: 10.2337/diacare.28.10.2541Cruz-Jentoft AJ, Baeyens JP, Bauer JM. Sarcopenia: European consensus on definition and diagnosis report of the European Working Group on Sarcopenia in Older People. Age and Ageing. 2010;39(4):412-23. doi: 10.1093/ageing/afq034Cruz-Jentoft AJ, Baeyens JP, Bauer JM. Sarcopenia: European consensus on definition and diagnosis report of the European Working Group on Sarcopenia in Older People. Age and Ageing. 2010;39(4):412-23. doi: 10.1093/ageing/afq034Studenski SA, Peters KW, Alley DE, et al. The FNIH sarcopenia project: rationale, study description, conference recommendations, and final estimates. J Gerontol Ser A Biol Sci Med Sci. 2014;69(5):547-58. doi: 10.1093/gerona/glu010Studenski SA, Peters KW, Alley DE, et al. The FNIH sarcopenia project: rationale, study description, conference recommendations, and final estimates. J Gerontol Ser A Biol Sci Med Sci. 2014;69(5):547-58. doi: 10.1093/gerona/glu010Fielding RA, Vellas B, Evans WJ, et al. Sarcopenia: an undiagnosed condition in older adults. Current consensus definition: prevalence, etiology, and consequences. International Working Group on Sarcopenia. J Am Med Dir Assoc. 2011;12(4):249-56. doi: 10.1016/j.jamda.2011.01.003Fielding RA, Vellas B, Evans WJ, et al. Sarcopenia: an undiagnosed condition in older adults. Current consensus definition: prevalence, etiology, and consequences. International Working Group on Sarcopenia. J Am Med Dir Assoc. 2011;12(4):249-56. doi: 10.1016/j.jamda.2011.01.003Anker SD, Morley JE, von Haehling S. Welcome to the ICD-10 code for sarcopenia. J Cachexia Sarcopenia Muscle. 2016;7(5):512-4. doi: 10.1002/jcsm.12147Anker SD, Morley JE, von Haehling S. Welcome to the ICD-10 code for sarcopenia. J Cachexia Sarcopenia Muscle. 2016;7(5):512-4. doi: 10.1002/jcsm.12147The WHOQoL Group. World Health Organization of Life Assessment (WHOQoL): position paper from the World Health Organization. Soc Sci Med. 1995;41(10):1403-9. doi: 10.1016/0277-9536(95)00112-kThe WHOQoL Group. World Health Organization of Life Assessment (WHOQoL): position paper from the World Health Organization. Soc Sci Med. 1995;41(10):1403-9. doi: 10.1016/0277-9536(95)00112-kPatel HP, Syddall HE, Jameson K, et al. Prevalence of sarcopenia in community-dwelling older people in the UK using the European Working Group on Sarcopenia in Older People (EWGSOP) definition: findings from the Hertfordshire Cohort Study (HCS). Age Ageing. 2013;42(3):378-84. doi: 10.1093/ageing/afs197Patel HP, Syddall HE, Jameson K, et al. Prevalence of sarcopenia in community-dwelling older people in the UK using the European Working Group on Sarcopenia in Older People (EWGSOP) definition: findings from the Hertfordshire Cohort Study (HCS). Age Ageing. 2013;42(3):378-84. doi: 10.1093/ageing/afs197Reginster J-Y, Cooper C, Rizzoli R, et al. Recommendations for the conduct of clinical trials for drugs to treat or prevent sarcopenia. Aging Clin Exp Res. 2015;28(1):47-58. doi: 10.1007/s40520-015-0517-yReginster J-Y, Cooper C, Rizzoli R, et al. Recommendations for the conduct of clinical trials for drugs to treat or prevent sarcopenia. Aging Clin Exp Res. 2015;28(1):47-58. doi: 10.1007/s40520-015-0517-yBeaudart C, Biver E, Reginster J-Y, et al. Development of a selfadministrated quality of life questionnaire for sarcopenia in elderly subjects: the SarQoL. Age Ageing. 2015;44(6):960-6. doi: 10.1093/ageing/afv133Beaudart C, Biver E, Reginster J-Y, et al. Development of a selfadministrated quality of life questionnaire for sarcopenia in elderly subjects: the SarQoL. Age Ageing. 2015;44(6):960-6. doi: 10.1093/ageing/afv133Beaudart C, Biver E, Reginster J-Y, et al. Validation of SarQoL®, a specific health-related quality of life questionnaire for sarcopenia. J Cachexia Sarcopenia Muscle. 2016;8(2):238-44. doi: 10.1002/jcsm.12149Beaudart C, Biver E, Reginster J-Y, et al. Validation of SarQoL®, a specific health-related quality of life questionnaire for sarcopenia. J Cachexia Sarcopenia Muscle. 2016;8(2):238-44. doi: 10.1002/jcsm.12149Terwee CB, Bot SDM, de Boer MR, et al. Quality criteria were proposed for measurement properties of health status questionnaires. J Clin Epidemiol. 2007;60(1):34-42. doi: 10.1016/j.jclinepi.2006.03.012Terwee CB, Bot SDM, de Boer MR, et al. Quality criteria were proposed for measurement properties of health status questionnaires. J Clin Epidemiol. 2007;60(1):34-42. doi: 10.1016/j.jclinepi.2006.03.012Beaton DE, Bombardier C, Guillemin F, et al. Guidelines for the process of cross-cultural adaptation of self-report measures. Spine. 2000;25(24):3186-91. doi: 10.1097/00007632-200012150-00014Beaton DE, Bombardier C, Guillemin F, et al. Guidelines for the process of cross-cultural adaptation of self-report measures. Spine. 2000;25(24):3186-91. doi: 10.1097/00007632-200012150-00014Cronbach LJ. Coefficient alpha and the internal structure of tests. Psychometrika. 1951;16(3):297-334. doi: 10.1007/BF02310555Cronbach LJ. Coefficient alpha and the internal structure of tests. Psychometrika. 1951;16(3):297-334. doi: 10.1007/BF02310555Nunnally JC. Psychometric theory New York: McGrawHill Inc.; 1994. Available from: http://www.amazon.com/PsychometricTheory-Jum-C-Nunnally/dp/007047849X (accessed 18 May 2015).Nunnally JC. Psychometric theory New York: McGrawHill Inc.; 1994. Available from: http://www.amazon.com/PsychometricTheory-Jum-C-Nunnally/dp/007047849X (accessed 18 May 2015).Deyo RA, Diehr P, Patrick DL. Reproducibility and responsiveness of health status measures. Statistics and strategies for evaluation. Control Clin Trials. 1991;12(4):142S-158S. doi: 10.1016/s0197-2456(05)80019-4Deyo RA, Diehr P, Patrick DL. Reproducibility and responsiveness of health status measures. Statistics and strategies for evaluation. Control Clin Trials. 1991;12(4):142S-158S. doi: 10.1016/s0197-2456(05)80019-4Syddall HE, Martin HJ, Harwood RH, et al. The SF-36: a simple, effective measure of mobility-disability for epidemiological studies. J Nutr Heal Aging. 2009;13(1):57-62. doi: 10.1007/s12603-009-0010-4Syddall HE, Martin HJ, Harwood RH, et al. The SF-36: a simple, effective measure of mobility-disability for epidemiological studies. J Nutr Heal Aging. 2009;13(1):57-62. doi: 10.1007/s12603-009-0010-4Rabin R, de Charro F. EQ-5D: a measure of health status from the EuroQol Group. Ann Med. 2001;33(5):337-43. doi: 10.3109/07853890109002087Rabin R, de Charro F. EQ-5D: a measure of health status from the EuroQol Group. Ann Med. 2001;33(5):337-43. doi: 10.3109/07853890109002087Beaudart C, Edwards M, Moss C, et al. English translation and validation of the SarQoL®, a quality of life questionnaire specific for sarcopenia. Age Ageing. 2017;46(2):271-6. doi: 10.1093/ageing/afw192Beaudart C, Edwards M, Moss C, et al. English translation and validation of the SarQoL®, a quality of life questionnaire specific for sarcopenia. Age Ageing. 2017;46(2):271-6. doi: 10.1093/ageing/afw192

The authors declare that there are no conflicts of interest present.