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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rsp</journal-id><journal-title-group><journal-title xml:lang="ru">Научно-практическая ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Rheumatology Science and Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-4484</issn><issn pub-type="epub">1995-4492</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1995-4484-2019-250-254</article-id><article-id custom-type="elpub" pub-id-type="custom">rsp-2722</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПЕРЕДОВАЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LEADING ARTICLE</subject></subj-group></article-categories><title-group><article-title>Можно ли предотвратить развитие псориатического артрита у пациентов с псориазом?</article-title><trans-title-group xml:lang="en"><trans-title>Can the development of psoriatic arthritis be prevented in patients with psoriasis?</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Насонов</surname><given-names>Е. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Nasonov</surname><given-names>E. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34А.</p><p>119991, Москва, ул. Трубецкая, 8, стр. 2.</p></bio><bio xml:lang="en"><p>34A, Kashirskoe Shosse, Moscow, 115522.</p><p>8, Trubetskaya Str., Build. 2, Moscow, 119991.</p></bio><email xlink:type="simple">nasonov@irramn.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коротаева</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Korotaeva</surname><given-names>T. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34А.</p></bio><bio xml:lang="en"><p>34A, Kashirskoe Shosse, Moscow, 115522.</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лила</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Lila</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34А.</p></bio><bio xml:lang="en"><p>34A, Kashirskoe Shosse, Moscow, 115522.</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кубанов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kubanov</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>107076, Москва, ул. Короленко, 6, стр. 6.</p></bio><bio xml:lang="en"><p>6, Korolenko Str., Build. 6, Moscow, 107076.</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»; ФГАОУ&#13;
ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова»&#13;
Минздрава России (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.A. Nasonova Research Institute of Rheumatology; I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.A. Nasonova Research Institute of Rheumatology</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБНУ «Государственный научный центр дерматовенерологии и косметологии» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State Scientific Center for Dermatovenerology and Cosmetology, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>08</day><month>07</month><year>2019</year></pub-date><volume>57</volume><issue>3</issue><fpage>250</fpage><lpage>254</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Насонов Е.Л., Коротаева Т.В., Лила А.М., Кубанов А.А., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Насонов Е.Л., Коротаева Т.В., Лила А.М., Кубанов А.А.</copyright-holder><copyright-holder xml:lang="en">Nasonov E.L., Korotaeva T.V., Lila A.M., Kubanov A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://rsp.mediar-press.net/rsp/article/view/2722">https://rsp.mediar-press.net/rsp/article/view/2722</self-uri><abstract><p>Псориатический артрит (ПсА) – хроническое иммуновоспалительное заболевание, которое, с одной стороны, рассматривается как наиболее частая коморбидная патология при псориазе в рамках «системной псориатической болезни», а с другой – классифицируется как клиническая форма спондилоартритов и находится на стыке фундаментальных проблем ревматологии и дерматологии. Изучение эволюции псориаза в направлении развития ПсА является приоритетным направлением исследований в ревматологии и дерматологии, имеющим важное значение для расшифровки природы гетерогенности и механизмов иммунопатогенеза этих заболеваний и разработки новых методов персонифицированной терапии на разных стадиях заболеваний.</p></abstract><trans-abstract xml:lang="en"><p>Psoriatic arthritis (PsA) is a chronic immunoinflammatory disease that, on the one hand, is considered as the most common comorbidity in psoriasis as part of systemic psoriatic disease, and, on the other, is classified as a clinical form of spondyloarthritis and lies at the interface of the basic problems of rheumatology and dermatology. The study of the evolution of psoriasis in relation to the development of PsA is a research priority area in rheumatology and dermatology, which is important for deciphering the nature of heterogeneity and the immunopathogenesis mechanisms of these diseases and for developing novel methods of personalized therapy at different stages of diseases.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>псориаз</kwd><kwd>псориатический артрит</kwd><kwd>иммуногенетика</kwd><kwd>биомаркеры</kwd></kwd-group><kwd-group xml:lang="en"><kwd>psoriasis</kwd><kwd>psoriatic arthritis</kwd><kwd>immunogenetics</kwd><kwd>biomarkers</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Scarpa R, Ayala F, Caporaso N, Olivieri I. Psoriasis, psoriatic arthritis, or psoriatic disease? 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