rspНаучно-практическая ревматологияRheumatology Science and Practice1995-44841995-4492IMA-PRESS, LLC10.14412/1995-4484-2019-328-332rsp-2734Research ArticleОБЗОРЫИзучение локальной и генерализованной потери костной ткани у больных ревматоидным артритомStudy of local and generalized bone loss in patients with rheumatoid arthritisДыдыкинаИ. С.DydykinaI. S.

115522, Москва, Каширское шоссе, 34А.

34A, Kashirskoe Shosse, Moscow 115522.

КожевниковаП. О.KozhevnikovaP. O.

115522, Москва, Каширское шоссе, 34А.

34A, Kashirskoe Shosse, Moscow 115522.

Pko31@list.ruФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»РоссияV.A. Nasonova Research Institute of RheumatologyRussian Federation201911072019573328332Copyright © Дыдыкина И.С., Кожевникова П.О., 20192019Дыдыкина И.С., Кожевникова П.О.Dydykina I.S., Kozhevnikova P.O.This work is licensed under a Creative Commons Attribution 4.0 License.https://rsp.mediar-press.net/rsp/article/view/2734

Хроническое воспаление при ревматоидном артрите (РА) сопровождается локальной (периартикулярный остеопороз) и генерализованной потерей минеральной плотности костной ткани осевого и периферического скелета. В статье обсуждается взаимосвязь между локальной и генерализованной потерей костной ткани и вклад различных факторов в костные изменения. Сведения о вкладе возраста на момент начала РА в прогрессирование деструктивных изменений кистей и стоп и скорость генерализованной потери костной ткани осевого и периферического скелета противоречивы.

Chronic inflammation in rheumatoid arthritis (RA) is accompanied by local (periarticular osteoporosis) and generalized loss of bone mineral density in the axial and peripheral skeleton. The paper discusses the relationship between local and generalized bone loss and the contribution of various factors to bone changes. Information about the contribution of age at the onset of RA to the progression of destructive changes in the hands and feet and the rate of generalized bone loss in the axial and peripheral skeleton are contradictory.

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