rspНаучно-практическая ревматологияRheumatology Science and Practice1995-44841995-4492IMA-PRESS, LLC10.14412/1995-4484-2019-333-338rsp-2735Research ArticleОБЗОРЫРоль биомаркеров в диагностике бактериальных инфекций при ревматических заболеванияхRole of biomarkers in the diagnosis of bacterial infections in rheumatic diseasesБеловБ. С.BelovB. S.

115522, Москва, Каширское шоссе, 34А.

34A, Kashirskoe Shosse, Moscow 115522.

belovbor@yandex.ruТарасоваГ. М.TarasovaG. M.

115522, Москва, Каширское шоссе, 34А.

34A, Kashirskoe Shosse, Moscow 115522.

МуравьеваН. В.MuravyevaN. V.

115522, Москва, Каширское шоссе, 34А.

34A, Kashirskoe Shosse, Moscow 115522.

ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»РоссияV.A. Nasonova Research Institute of RheumatologyRussian Federation201911072019573333338Copyright © Белов Б.С., Тарасова Г.М., Муравьева Н.В., 20192019Белов Б.С., Тарасова Г.М., Муравьева Н.В.Belov B.S., Tarasova G.M., Muravyeva N.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://rsp.mediar-press.net/rsp/article/view/2735

В современной ревматологии проблема дифференциальной диагностики бактериальной инфекции и активного ревматического процесса по-прежнему сохраняет свою актуальность. При этом весьма важен вопрос поиска биомаркера – «золотого стандарта» диагностики инфекции у пациентов с ревматическими заболеваниями (РЗ) в целях быстрого определения тактики лечения. В настоящем обзоре проанализированы диагностическая значимость и возможность применения некоторых лабораторных маркеров бактериальных инфекций в современной ревматологии. Подчеркивается важность мультимаркерного подхода, позволяющего увеличить значимость отдельных параметров в диагностике инфекций при РЗ.

In modern rheumatology, the problem of differential diagnosis of bacterial infection and active rheumatic process still retains its relevance. At the same time, it is very important to search for a biomarker - the gold standard for the diagnosis of an infection in patients with rheumatic diseases (RDs) in order to rapidly determine a treatment policy. This review analyzes the diagnostic significance and possibility of using some laboratory markers for bacterial infections in modern rheumatology. It emphasizes the importance of a multimarker approach that allows increasing the significance of individual parameters in the diagnosis of infections in RD.

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The authors declare that there are no conflicts of interest present.