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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rsp</journal-id><journal-title-group><journal-title xml:lang="ru">Научно-практическая ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Rheumatology Science and Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-4484</issn><issn pub-type="epub">1995-4492</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1995-4484-2019-462-467</article-id><article-id custom-type="elpub" pub-id-type="custom">rsp-2760</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ФОРУМ МОЛОДЫХ УЧЕНЫХ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>YOUNG SCIENTISTS FORUM</subject></subj-group></article-categories><title-group><article-title>Факторы, влияющие на качество жизни, связанное со здоровьем, у пациентов с системной красной волчанкой</article-title><trans-title-group xml:lang="en"><trans-title>FACTORS INFLUENCING HEALTH-RELATED QUALITY OF LIFE IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Воробьева</surname><given-names>Л. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Vorobyeva</surname><given-names>L. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант ФГБНУ «НИИР им. В.А. Насоновой» (научный руководитель – к.м.н. Е.А. Асеева)</p><p>115522, Москва, Каширское шоссе, 34А</p></bio><bio xml:lang="en"><p>34A, Kashirskoe Shosse, Moscow 115522</p></bio><email xlink:type="simple">evagolland@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт ревматологии им. В.А Насоновой»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.A. Nasonova Research Institute of Rheumatology</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>16</day><month>09</month><year>2019</year></pub-date><volume>57</volume><issue>4</issue><fpage>462</fpage><lpage>467</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Воробьева Л.Д., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Воробьева Л.Д.</copyright-holder><copyright-holder xml:lang="en">Vorobyeva L.D.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://rsp.mediar-press.net/rsp/article/view/2760">https://rsp.mediar-press.net/rsp/article/view/2760</self-uri><abstract><p>Системная красная волчанка (СКВ) – хроническое аутоиммунное заболевание, которое поражает любые органы и системы и характеризуется широким спектром разнообразных клинических проявлений. Согласно стратегии «Лечение до достижения цели» (Treat to Target) при СКВ, помимо контроля активности заболевания и необратимых органных повреждений, необходимо проводить оценку качества жизни, связанного со здоровьем (КЖСЗ), что позволяет получить полную и объективную характеристику пациента. Необходимо также учитывать все те факторы и проблемы, которые могут ухудшать КЖСЗ. В качестве главных симптомов, которые в значительной степени влияют на КЖСЗ, выделяют усталость, боль и депрессию. Также учитывается влияние когнитивных нарушений, связанных с заболеванием. Немаловажной проблемой для больных СКВ является нарушение образа тела, т. е. восприятия своего внешнего облика самим пациентом. Непредсказуемость течения заболевания и нарушение физического функционирования больных затрудняют выполнение повседневных функций, нарушается социализация, пациенты часто испытывают зависимость от других людей. Из-за СКВ пациенты часто ограничены в выборе своей профессии или вынуждены прекращать/менять работу, что приводит к финансовым потерям и ощущению изоляции от общества. Также в обзоре рассматриваются в качестве факторов, влияющих на КЖСЗ, пол, возраст и наличие образования у пациентов с СКВ.</p></abstract><trans-abstract xml:lang="en"><p>Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affects any organs and systems and is characterized by a wide range of various clinical manifestations. According to the treat-to-target strategy for SLE, in addition to monitoring disease activity and irreversible organ damage, it is necessary to assess health-related quality of life (HRQOL), which enables one to obtain a complete and objective description of the patient. All the factors and problems that may worsen HRQOL should be also taken into account. Fatigue, pain, and depression are identified as the major symptoms that largely affect HRQOL. The impact of cognitive impairment associated with the disease is also considered. Impaired body image, i.e. the perception of his own appearance by a patient himself, is an important problem in patients with SLE. The unpredictable course of the disease and the impaired physical functioning of patients make it difficult to perform everyday activities, as well as disturb socialization; the patients often experience of being dependent on others. Due to SLE, the patients are often limited in their choice of profession or forced to quit/change their jobs, which leads to financial losses and feelings of social isolation. The review also considers gender, age, and education as factors influencing HRQOL in patients with SLE.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>системная красная волчанка</kwd><kwd>качество жизни</kwd><kwd>связанное со здоровьем</kwd></kwd-group><kwd-group xml:lang="en"><kwd>systemic lupus erythematosus</kwd><kwd>health-related quality of life</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Majdan M. Toczen rumieniowaty ukladowy w Polsce. Raport. 2012. Access: 4.02.2016.</mixed-citation><mixed-citation xml:lang="en">Majdan M. Toczen rumieniowaty ukladowy w Polsce. Raport. 2012. Access: 4.02.2016.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Navarrete-Navarrete N, Peralta-Ramirez MI, Sabio JM, et al. 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