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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rsp</journal-id><journal-title-group><journal-title xml:lang="ru">Научно-практическая ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Rheumatology Science and Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-4484</issn><issn pub-type="epub">1995-4492</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1995-4484-2008-6</article-id><article-id custom-type="elpub" pub-id-type="custom">rsp-290</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Анти-В клеточная терапия синдрома и болезни Шёгрена</article-title><trans-title-group xml:lang="en"><trans-title>Anti-V kletochnaya terapiya sindroma i bolezni Shegrena</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Vasil'ev</surname><given-names>V I</given-names></name><name name-style="western" xml:lang="en"><surname>Vasil'ev</surname><given-names>V I</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Логвиненко</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Logvinenko</surname><given-names>O A</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Kokosadze</surname><given-names>N V</given-names></name><name name-style="western" xml:lang="en"><surname>Kokosadze</surname><given-names>N V</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Насонов</surname><given-names>Евгений Львович</given-names></name><name name-style="western" xml:lang="en"><surname>Nasonov</surname><given-names>E L</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib></contrib-group><pub-date pub-type="collection"><year>2008</year></pub-date><pub-date pub-type="epub"><day>15</day><month>02</month><year>2008</year></pub-date><volume>46</volume><issue>1s</issue><issue-title>№1s (2008)</issue-title><fpage>34</fpage><lpage>39</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Vasil'ev V.I., Логвиненко О.А., Kokosadze N.V., Насонов Е.Л., 2008</copyright-statement><copyright-year>2008</copyright-year><copyright-holder xml:lang="ru">Vasil'ev V.I., Логвиненко О.А., Kokosadze N.V., Насонов Е.Л.</copyright-holder><copyright-holder xml:lang="en">Vasil'ev V.I., Logvinenko O.A., Kokosadze N.V., Nasonov E.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://rsp.mediar-press.net/rsp/article/view/290">https://rsp.mediar-press.net/rsp/article/view/290</self-uri></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">&lt;div&gt;&lt;p&gt;Васильев В.И., Симонова М.В., Сафонова Т.Н. Болезнь Шёгрена. В кн. Насонова В.А., Бунчук Н.В. (ред.), Ревматические болезни, М., Медицина; 1997, 196-210.&lt;/p&gt;&lt;p&gt;Васильев В.И., Пробатова Н.А., Тупицын Н.Н. и др. Лимфопролифера- тивные заболевания при болезни Шёгрена. Онкогематология 2007; 3 : 16-26.&lt;/p&gt;&lt;p&gt;Kassan S.S., Thomas T.L., Mout- sopoulos H.M., et al. Increased risk of lymphoma in sicca syndrome. Ann. Intern. Med.1978, 89: 888-892.&lt;/p&gt;&lt;p&gt;Voulgarelis М., Dafni U.G., Isenberg D. A., et al. Malignant lymphoma in primary Sj?gren's syndrome. A multicenter, retrospective, clinical study by the European Concerted Action on Sjgren's syndrome. Arthritis Rheum.1999; 42: 1765-1772.&lt;/p&gt;&lt;p&gt;Васильев В.И., Пробатова Н.А., Тупицин Н.Н. и др. MALT-лимфомы при болезни Шёгрена. Тер.Арх. 2006; 1, 45-49.&lt;/p&gt;&lt;p&gt;Harris N.L. Lymphoid proliferations of the salivary glands. Am.J.Clin.Pathol. 1999; 111 (Suppl. 1): 94-103.&lt;/p&gt;&lt;p&gt;Васильев В.И. Болезнь Шёгрена: клинико-лабораторные, иммуноморфо- логические проявления и прогноз. Дис. док.мед.наук - Москва, 2007.&lt;/p&gt;&lt;p&gt;Поддубная И.В. Лечение индолент- ных неходжкинских лимфом. Практическая Онкология. 2004; 5(3): 203-208.&lt;/p&gt;&lt;p&gt;Насонов Е.Л., Соловьев С.К. Перспективы применения моноклональных антител к В-лимфоцитам (Ритуксимаб) при воспалительных ревматических заболеваниях. Научно-практическая ревматология. 2007; 1:4-8.&lt;/p&gt;&lt;p&gt;Silverman G.J., Weisman S. Rituximab therapy and autoimmune disorders. Arthr.Rheum. 2003; 48(6): 1484-1491.&lt;/p&gt;&lt;p&gt;Cohen S.B. В-cell depletion for rheumatic disease: where are we? Med.Gen.Med. 2005 ; 7(2):1-13.&lt;/p&gt;&lt;p&gt;Родионова E.B., Васильев В.И., Прокопенко В.Д., Логвиненко О.А. Антигенпредставляющие клетки лимфо- гистиоцитарного инфильтрата при болезни Шёгрена. Научно-практическая ревматология. 2006; 3 : 16-20.&lt;/p&gt;&lt;p&gt;Harris N., Jaffe Е., Diebold J et al. The World Health Organization classification of neoplastic diseases of the hematopoetic and lymphoid tissues: report of the clinical advisory committee Meeting, Airlie House, Virginia, November, 1997. Ann.Oncol.1999; 10: 14191432.&lt;/p&gt;&lt;p&gt;Carbone P.P., Kaplan H.S., Musshoff K. et al. Report on the Committee on Hodgkin ’s Desease Studing Classification. Cancer Res.1971;31 : 1860-1861.&lt;/p&gt;&lt;p&gt;Shih W.J., Ghesani N., Hongming Z. et al. F-18 FDG positron emission tomography demonstrates resolution of non-Hodgkin's lymphoma of parotid gland in a patient with Sjogren's syndrome: before and after anti- CD20 antibody rituximab therapy. Clin. Nucl.Med.2002; 27: 142-143.&lt;/p&gt;&lt;p&gt;Somer B.G., Tsai D.E., Downs L. et.al. Improvement in Sjogren’s syndrome following therapy with rituximab for marginal zone lymphoma. Arthr.Rheum.2003; 49(3): 394-398.&lt;/p&gt;&lt;p&gt;Voulgarelis М., Giannouli S., Anagnostou D., Tzioufas A.G. Combined therapy with rituximab plus cyclophosphamide/doxorubicin/vincristine/prednisone [CHOP] for Sjogren's syndrome-associated В-cell aggressive non-Hodgkin’s lymphomas. Rheumatology [Oxford].2004; 43: 10501053.&lt;/p&gt;&lt;p&gt;Harner R.S.,Jockson L.W., Drabick J. J. Normalization of anticardiolipin antibodies following rituximab therapy for marginal zone lymphoma in a patient with Sjogren’s syndrome. Rheumatology [Oxford],2004; 43 : 1309-1310.&lt;/p&gt;&lt;p&gt;Ramos-Casals М., Lopez-Guillermo A., Brito-Zeron P. et al. Treatment of B-cell lymphoma with rituximab in two patients with Sjogren's syndrome associated with hepatitis С virus infection. Lupus.2004; 13: 969-971.&lt;/p&gt;&lt;p&gt;Pijpe J., Imhoff G.W., Vissink A. et al. Changes in salivary gland immunohistology and function after rituximab monotherapy in a patient with Sjogren's syndrome and associated MALT lymphoma. Ann.Rhtum.Dis. 2005; 64:958-960.&lt;/p&gt;&lt;p&gt;Ring Т., Kallenbach М., Praetorius J. et al. Successful treatment of a patient with primary Sjogren's syndrome with Rituximab. Clin.Rheumatol.2006; 25 : 891-894.&lt;/p&gt;&lt;p&gt;Serror R., Sordet C., Guillevin L. Et al. Tolerance and efficacy of rituximab and changes in serum В cell biomarkers in patients with systemic complications of primary Sjogren's syndrome. Ann.Rheum.Dis. 2007; 66(3): 351-358.&lt;/p&gt;&lt;p&gt;Pijpe P., van Imhoff G.W., Spijkervet F.K., et al. Rituximab treatment in patients with Sjogren's syndrome: an open-label phase II study. Arthritis Rheum. 2005, 52 (9), 27402750.&lt;/p&gt;&lt;p&gt;Deyauchelle-Pensec V., Pennec Y, Morvan J. et al. Improvement of Sjogren's sendrome after two infusions of Rituximab (Anti-CD20). Arthr.Rheum.2007; 57(2) : 310317.&lt;/p&gt;&lt;p&gt;Cavalli F., Isaacson P.G., Gascoyne R.D., Zucca E. MALT Lymphas. Hematology. 2001; 241-258&lt;/p&gt;&lt;p&gt;Voulgarelis М., Giannjuli S., Tzioufas A. G., Moutsopoulos H.M. Long term remission of Sjogren’s syndrome associated aggressive В cell non-Hodgkin's lymphomas following combined В cell depletion therapy and CHOP (cyclophosphamide, doxorubicin, vincristine, prednisone). Ann. Rheum. Dis. 2006; 65 : 1033-1037.&lt;/p&gt;&lt;p&gt;Васильев В.И., Соловьев С.К., Логвиненко О.А., Насонов Е.Л. Успешное применение Ритуксимаба при "катастрофическом" течении системной красной волчанки с синдромом Шёгрена. Научнопрактическая ревматология.2006; 3 : 3337.&lt;/p&gt;&lt;p&gt;Gottenberg J.E., Guillevin L., Lam- botte О. Et al. Tolerance and shortterm efficacy of rituximab in 43 patients with systemic autoimmune diseases. Ann. Rheum.Dis.2005; 64:913-920&lt;/p&gt;&lt;/div&gt;&lt;br /&gt;</mixed-citation><mixed-citation xml:lang="en">&lt;div&gt;&lt;p&gt;Васильев В.И., Симонова М.В., Сафонова Т.Н. Болезнь Шёгрена. В кн. Насонова В.А., Бунчук Н.В. (ред.), Ревматические болезни, М., Медицина; 1997, 196-210.&lt;/p&gt;&lt;p&gt;Васильев В.И., Пробатова Н.А., Тупицын Н.Н. и др. Лимфопролифера- тивные заболевания при болезни Шёгрена. Онкогематология 2007; 3 : 16-26.&lt;/p&gt;&lt;p&gt;Kassan S.S., Thomas T.L., Mout- sopoulos H.M., et al. Increased risk of lymphoma in sicca syndrome. Ann. Intern. Med.1978, 89: 888-892.&lt;/p&gt;&lt;p&gt;Voulgarelis М., Dafni U.G., Isenberg D. A., et al. Malignant lymphoma in primary Sj?gren's syndrome. A multicenter, retrospective, clinical study by the European Concerted Action on Sjgren's syndrome. Arthritis Rheum.1999; 42: 1765-1772.&lt;/p&gt;&lt;p&gt;Васильев В.И., Пробатова Н.А., Тупицин Н.Н. и др. MALT-лимфомы при болезни Шёгрена. Тер.Арх. 2006; 1, 45-49.&lt;/p&gt;&lt;p&gt;Harris N.L. Lymphoid proliferations of the salivary glands. Am.J.Clin.Pathol. 1999; 111 (Suppl. 1): 94-103.&lt;/p&gt;&lt;p&gt;Васильев В.И. Болезнь Шёгрена: клинико-лабораторные, иммуноморфо- логические проявления и прогноз. Дис. док.мед.наук - Москва, 2007.&lt;/p&gt;&lt;p&gt;Поддубная И.В. Лечение индолент- ных неходжкинских лимфом. Практическая Онкология. 2004; 5(3): 203-208.&lt;/p&gt;&lt;p&gt;Насонов Е.Л., Соловьев С.К. Перспективы применения моноклональных антител к В-лимфоцитам (Ритуксимаб) при воспалительных ревматических заболеваниях. Научно-практическая ревматология. 2007; 1:4-8.&lt;/p&gt;&lt;p&gt;Silverman G.J., Weisman S. Rituximab therapy and autoimmune disorders. Arthr.Rheum. 2003; 48(6): 1484-1491.&lt;/p&gt;&lt;p&gt;Cohen S.B. В-cell depletion for rheumatic disease: where are we? Med.Gen.Med. 2005 ; 7(2):1-13.&lt;/p&gt;&lt;p&gt;Родионова E.B., Васильев В.И., Прокопенко В.Д., Логвиненко О.А. Антигенпредставляющие клетки лимфо- гистиоцитарного инфильтрата при болезни Шёгрена. Научно-практическая ревматология. 2006; 3 : 16-20.&lt;/p&gt;&lt;p&gt;Harris N., Jaffe Е., Diebold J et al. The World Health Organization classification of neoplastic diseases of the hematopoetic and lymphoid tissues: report of the clinical advisory committee Meeting, Airlie House, Virginia, November, 1997. Ann.Oncol.1999; 10: 14191432.&lt;/p&gt;&lt;p&gt;Carbone P.P., Kaplan H.S., Musshoff K. et al. Report on the Committee on Hodgkin ’s Desease Studing Classification. Cancer Res.1971;31 : 1860-1861.&lt;/p&gt;&lt;p&gt;Shih W.J., Ghesani N., Hongming Z. et al. F-18 FDG positron emission tomography demonstrates resolution of non-Hodgkin's lymphoma of parotid gland in a patient with Sjogren's syndrome: before and after anti- CD20 antibody rituximab therapy. Clin. Nucl.Med.2002; 27: 142-143.&lt;/p&gt;&lt;p&gt;Somer B.G., Tsai D.E., Downs L. et.al. Improvement in Sjogren’s syndrome following therapy with rituximab for marginal zone lymphoma. Arthr.Rheum.2003; 49(3): 394-398.&lt;/p&gt;&lt;p&gt;Voulgarelis М., Giannouli S., Anagnostou D., Tzioufas A.G. Combined therapy with rituximab plus cyclophosphamide/doxorubicin/vincristine/prednisone [CHOP] for Sjogren's syndrome-associated В-cell aggressive non-Hodgkin’s lymphomas. Rheumatology [Oxford].2004; 43: 10501053.&lt;/p&gt;&lt;p&gt;Harner R.S.,Jockson L.W., Drabick J. J. Normalization of anticardiolipin antibodies following rituximab therapy for marginal zone lymphoma in a patient with Sjogren’s syndrome. Rheumatology [Oxford],2004; 43 : 1309-1310.&lt;/p&gt;&lt;p&gt;Ramos-Casals М., Lopez-Guillermo A., Brito-Zeron P. et al. Treatment of B-cell lymphoma with rituximab in two patients with Sjogren's syndrome associated with hepatitis С virus infection. Lupus.2004; 13: 969-971.&lt;/p&gt;&lt;p&gt;Pijpe J., Imhoff G.W., Vissink A. et al. Changes in salivary gland immunohistology and function after rituximab monotherapy in a patient with Sjogren's syndrome and associated MALT lymphoma. Ann.Rhtum.Dis. 2005; 64:958-960.&lt;/p&gt;&lt;p&gt;Ring Т., Kallenbach М., Praetorius J. et al. Successful treatment of a patient with primary Sjogren's syndrome with Rituximab. Clin.Rheumatol.2006; 25 : 891-894.&lt;/p&gt;&lt;p&gt;Serror R., Sordet C., Guillevin L. Et al. Tolerance and efficacy of rituximab and changes in serum В cell biomarkers in patients with systemic complications of primary Sjogren's syndrome. Ann.Rheum.Dis. 2007; 66(3): 351-358.&lt;/p&gt;&lt;p&gt;Pijpe P., van Imhoff G.W., Spijkervet F.K., et al. Rituximab treatment in patients with Sjogren's syndrome: an open-label phase II study. Arthritis Rheum. 2005, 52 (9), 27402750.&lt;/p&gt;&lt;p&gt;Deyauchelle-Pensec V., Pennec Y, Morvan J. et al. Improvement of Sjogren's sendrome after two infusions of Rituximab (Anti-CD20). Arthr.Rheum.2007; 57(2) : 310317.&lt;/p&gt;&lt;p&gt;Cavalli F., Isaacson P.G., Gascoyne R.D., Zucca E. MALT Lymphas. Hematology. 2001; 241-258&lt;/p&gt;&lt;p&gt;Voulgarelis М., Giannjuli S., Tzioufas A. G., Moutsopoulos H.M. Long term remission of Sjogren’s syndrome associated aggressive В cell non-Hodgkin's lymphomas following combined В cell depletion therapy and CHOP (cyclophosphamide, doxorubicin, vincristine, prednisone). Ann. Rheum. Dis. 2006; 65 : 1033-1037.&lt;/p&gt;&lt;p&gt;Васильев В.И., Соловьев С.К., Логвиненко О.А., Насонов Е.Л. Успешное применение Ритуксимаба при "катастрофическом" течении системной красной волчанки с синдромом Шёгрена. Научнопрактическая ревматология.2006; 3 : 3337.&lt;/p&gt;&lt;p&gt;Gottenberg J.E., Guillevin L., Lam- botte О. Et al. Tolerance and shortterm efficacy of rituximab in 43 patients with systemic autoimmune diseases. Ann. Rheum.Dis.2005; 64:913-920&lt;/p&gt;&lt;/div&gt;&lt;br /&gt;</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
