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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rsp</journal-id><journal-title-group><journal-title xml:lang="ru">Научно-практическая ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Rheumatology Science and Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-4484</issn><issn pub-type="epub">1995-4492</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.47360/1995-4484-2021-103-107</article-id><article-id custom-type="elpub" pub-id-type="custom">rsp-2997</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКОЕ НАБЛЮДЕНИЕ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL OBSERVATIONS</subject></subj-group></article-categories><title-group><article-title>Два случая острой уратной нефропатии у женщин с асимптомной гиперурикемией</article-title><trans-title-group xml:lang="en"><trans-title>Two cases of acute urate nephropathy in women with asymptomatic hyperuricemia</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5275-3261</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Елисеева</surname><given-names>Л. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Yeliseyeva</surname><given-names>L. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Елисеева Людмила Николаевна</p><p>350086, Краснодар, ул. Митрофана Седина, 4</p></bio><bio xml:lang="en"><p>Ludmila Yeliseyeva</p><p>350086, Krasnodar, Mitrofana Sedina str., 4</p><p> </p></bio><email xlink:type="simple">Yeliseyeva@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7121-6456</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Куринная</surname><given-names>В. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Kurinnaya</surname><given-names>V. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>350063, Краснодар, ул. 1 Мая, 167</p></bio><bio xml:lang="en"><p>Valeriya P. Kurinnaya</p><p>350063, Krasnodar, Pervogo Maya str., 167</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7866-2288</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Понкина</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Ponkina</surname><given-names>O. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>350063, Краснодар, ул. 1 Мая, 167</p></bio><bio xml:lang="en"><p>Olga N. Ponkina</p><p>350063, Krasnodar, Pervogo Maya str., 167</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1393-4059</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Семизарова</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Semizarova</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>350086, Краснодар, ул. Митрофана Седина, 4</p></bio><bio xml:lang="en"><p>Irina V. Semizarova</p><p>350086, Krasnodar, Mitrofana Sedina str., 4</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4276-0350</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Басте</surname><given-names>З. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Baste</surname><given-names>Z. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>350086, Краснодар, ул. Митрофана Седина, 4</p></bio><bio xml:lang="en"><p>Zara A. Baste</p><p>350086, Krasnodar, Mitrofana Sedina str., 4</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ФГБОУ ВО «Кубанский государственный медицинский университет» Минздрава России<country>Россия</country></aff><aff xml:lang="en">Kuban State Medical University<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">ГБУЗ «НИИ – Краевая клиническая больница № 1 им. С.В. Очаповского» Министерства здравоохранения Краснодарского края<country>Россия</country></aff><aff xml:lang="en">Research Institute – Regional Clinical Hospital N 1 named after S.V. Ochapovsky<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>03</day><month>03</month><year>2021</year></pub-date><volume>59</volume><issue>1</issue><fpage>103</fpage><lpage>107</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Елисеева Л.Н., Куринная В.П., Понкина О.Н., Семизарова И.В., Басте З.А., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Елисеева Л.Н., Куринная В.П., Понкина О.Н., Семизарова И.В., Басте З.А.</copyright-holder><copyright-holder xml:lang="en">Yeliseyeva L.N., Kurinnaya V.P., Ponkina O.N., Semizarova I.V., Baste Z.A.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://rsp.mediar-press.net/rsp/article/view/2997">https://rsp.mediar-press.net/rsp/article/view/2997</self-uri><abstract><p>Приводится описание двух собственных наблюдений развития острой уратной нефропатии у женщин с асимптомной гиперурикемией. Представлены клинические данные и результаты дополнительных лабораторных и инструментальных исследований, в одном из наблюдений описана морфологическая картина прижизненного биопсийного материала на фоне длительного применения диуретиков. Второй случай характеризует тофусное поражение почек (по данным патолого-анатомического исследования) без характерных клинических проявлений подагры. Авторы обращают внимание на необходимость исследования уровня мочевой кислоты сыворотки крови во всех случаях острого повреждения почек.</p></abstract><trans-abstract xml:lang="en"><p>The article presents a description of two own observations of the development of acute urate nephropathy in women with asymptomatic hyperuricemia. Clinical data and the results of additional laboratory and instrumental studies are presented; in one of the observations, the morphological picture of intravital biopsy material against the background of prolonged use of diuretics is described. The second case characterizes tophus kidney damage (according to the pathological examination data) without characteristic clinical manifestations of gout in vivo. The authors draw attention to the need to study serum uric acid levels in all cases of acute kidney injury.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>подагра</kwd><kwd>гиперурикемия</kwd><kwd>острая уратная нефропатия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>gout</kwd><kwd>hyperuricemia</kwd><kwd>acute urate nephropathy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Клинические рекомендации по диагностике и лечению острого почечного повреждения. Москва, 2014 г.</mixed-citation><mixed-citation xml:lang="en">Clinical practice guidelines for the diagnosis and treatment of acute renal injury. 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