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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rsp</journal-id><journal-title-group><journal-title xml:lang="ru">Научно-практическая ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Rheumatology Science and Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-4484</issn><issn pub-type="epub">1995-4492</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.47360/1995-4484-2021-418-425</article-id><article-id custom-type="elpub" pub-id-type="custom">rsp-3059</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>Сравнение стандартной рентгенографии и магнитно-резонансной томографии при остеоартрите суставов кистей</article-title><trans-title-group xml:lang="en"><trans-title>Comparison of standard radiography and magnetic resonance imaging in hand osteoarthritis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1084-3920</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кудинский</surname><given-names>Д. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Kudinskii</surname><given-names>D. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Российская Федерация, Москва, Каширское шоссе, 34а</p></bio><bio xml:lang="en"><p>115522, Russian Federation, Moscow, Kashirskoye Highway, 34A</p></bio><email xlink:type="simple">Jet56@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7418-9369</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Смирнов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Smirnov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Российская Федерация, Москва, Каширское шоссе, 34а</p></bio><bio xml:lang="en"><p>115522, Russian Federation, Moscow, Kashirskoye Highway, 34A</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7017-0898</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алексеева</surname><given-names>Л. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Alekseeva</surname><given-names>L. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Российская Федерация, Москва, Каширское шоссе, 34а</p><p>125993, Российская Федерация, Москва, ул. Баррикадная, 2/1, стр. 1</p></bio><bio xml:lang="en"><p>115522, Russian Federation, Moscow, Kashirskoye Highway, 34A</p><p>125993, Russian Federation, Moscow, Barrikadnaya str., 2/1, building 1</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8218-3223</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Таскина</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Taskina</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Российская Федерация, Москва, Каширское шоссе, 34а</p></bio><bio xml:lang="en"><p>115522, Russian Federation, Moscow, Kashirskoye Highway, 34A</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6068-3080</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лила</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Lila</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Российская Федерация, Москва, Каширское шоссе, 34а</p><p>125993, Российская Федерация, Москва, ул. Баррикадная, 2/1, стр. 1</p></bio><bio xml:lang="en"><p>115522, Russian Federation, Moscow, Kashirskoye Highway, 34A</p><p>125993, Russian Federation, Moscow, Barrikadnaya str., 2/1, building 1</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8627-5341</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Потапова</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Potapova</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Российская Федерация, Москва, Каширское шоссе, 34а</p></bio><bio xml:lang="en"><p>115522, Russian Federation, Moscow, Kashirskoye Highway, 34A</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1784-3699</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Волков</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Volkov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Российская Федерация, Москва, Каширское шоссе, 34а</p></bio><bio xml:lang="en"><p>115522, Russian Federation, Moscow, Kashirskoye Highway, 34A</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.A. Nasonova Research Institute of Rheumatology</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»; ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.A. Nasonova Research Institute of Rheumatology; Russian Medical Academy of Continuous Professional Education of the Ministry of Healthcare of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>05</day><month>09</month><year>2021</year></pub-date><volume>59</volume><issue>4</issue><elocation-id>418–425</elocation-id><permissions><copyright-statement>Copyright &amp;#x00A9; Кудинский Д.М., Смирнов А.В., Алексеева Л.И., Таскина Е.А., Лила А.М., Потапова А.С., Волков А.В., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Кудинский Д.М., Смирнов А.В., Алексеева Л.И., Таскина Е.А., Лила А.М., Потапова А.С., Волков А.В.</copyright-holder><copyright-holder xml:lang="en">Kudinskii D.M., Smirnov A.V., Alekseeva L.I., Taskina E.A., Lila A.M., Potapova A.S., Volkov A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://rsp.mediar-press.net/rsp/article/view/3059">https://rsp.mediar-press.net/rsp/article/view/3059</self-uri><abstract><p>Цель исследования – провести сравнительную оценку методик стандартной рентгенографии и магнитно- резонансной томографии (МРТ) в определении сужения суставных щелей (ССЩ), остеофитов (ОФ), эрозий и подвывихов дистальных межфаланговых (ДМФС) и проксимальных межфаланговых суставов (ПМФС), кортикальных дефектов и подвывихов пястно-фаланговых (ПЯФС) суставов правой кисти и определить показания для назначения МРТ больным с остеоартритом суставов кистей (ОА СК).</p><sec><title>Материалы и методы</title><p>Материалы и методы. В исследование включены 64 женщины с клинически верифицированным (по критериям АСR (American College of Rheumatology)) диагнозом ОА СК, которым выполнялись рентгенография суставов правой кисти в передне-задней проекции и МРТ. Средний возраст пациенток составил 65,28±6,82 года, возраст начала болезни – 48,81±7,73 года, продолжительность заболевания – 15,0 (10,0– 19,5) лет. Рентгенограммы были описаны в соответствии со шкалой Келлгрена и Лоуренса, магнитно-резо- нансные томограммы были проанализированы в соответствии с модифицированной системой Oslo Hand Osteoarthritis Score (OHOA). Сравнение методик проводилось на основании обнаружения 4 симптомов, выявляемых при рентгенографии и МРТ: ССЩ, наличия ОФ, эрозий и подвывихов.</p></sec><sec><title>Результаты</title><p>Результаты. Обе методики показали примерно равное выявление ССЩ в ДМФС, ПМФС и ПЯФС. ОФ обнаруживались у 88% пациенток в ДМФС по данным рентгенографии и у 95% – при использовании МРТ (p&gt;0,05). При МРТ по сравнению со стандартной рентгенографией отмечалось более частое выявление ОФ в ПМФС (86% против 70%; p=0,027) и ПЯФС (66% и 45%; p=0,03). Эрозии в ДМФС были обнаружены у 41% больных по данным МРТ и у 34% – в результате рентгенологического исследования (р&gt;0,05), эрозии в ПМФС – в 27% и 13% случаев (p=0,037), кортикальные дефекты в ПЯФС – в 60% и 8% случаев соответственно (p=4,28e–10). Подвывихи определялись в ДМФС в 23% случаев на рентгенограммах и в 31% – по данным МРТ (р&gt;0,05), в ПМФС – в 8% и 6% соответственно (p&gt;0,05), в ПЯФС подвывихи практически не встречались – в 3% случаев по данным стандартной рентгенографии.</p></sec><sec><title>Выводы</title><p>Выводы. МРТ при ОА суставов кистей может применяться для обнаружения эрозивного процесса, проведения дифференциальной диагностики с другими заболеваниями суставов, определения воспалительных изменений в кистях и оценки степени их выраженности, однако не имеет значимых преимуществ перед стандартной рентгенографией в определении признаков дегенеративно-дистрофических изменений (ССЩ и ОФ). Подвывихи ПЯФС не характерны для ОА.</p></sec></abstract><trans-abstract xml:lang="en"><p>Standard radiography in direct projection is the “gold standard” in the diagnosis of hand osteoarthritis (HOA). However, the currently clinically most severe “erosive” or “inflammatory” phenotype of HOA is characterized by the presence of inflammatory symptoms such as bone marrow lession (BML), synovitis and tenosinovitis, which are not visible on the radiograph by the nature of the study due to the low optical density. In addition, X-ray examination is planar and has no possibility of multiplanar visualization. This dictated the need to search for a more informative visualization technique in HOA.</p><p>Aim – to compare the sensitivity and specificity of standard radiography and magnetic resonance imaging (MRI) techniques in determining the symptoms of osteoarthritis (OA) of the distal interphalangeal (DIP), proximal interphalangeal (PIP) and metacarpophalangeal (MCP) joints of the right hand; to determine the indications for the appointment of MRI in patients with HOA.</p><sec><title>Materials and methods</title><p>Materials and methods. The study included 64 women with clinically verified diagnosis of HOA according to ask criteria. For the first time, X-rays of the joints of the right hand in the anterior-posterior projection and MRI were performed for each of them. Each patient completed the AUSCAN questionnaire. X-rays were described according to the Kellgren and Lawrence systems, magnetic resonance imaging was analyzed according to the modified OHOA system. The sensitivity and specificity of the methods were compared based on the detection of 4 symptoms detected by radiography and MRI: joint space narrowing (JSN), osteophytes (OP), erosions and subluxations. The average age of the patients was 65.28±6.82 years, the age of onset was 48.81±7.73 years, the duration of the disease was 15.0 (10.0–19.5) years.</p></sec><sec><title>Results</title><p>Results. Both methods showed approximately equal identification JSN symptom in DIP and PIP, 95% definition JSN in MCP. OP were detected in 88% of patients in DIP according to radiography and in 95% – using MRI (p&gt;0.05). In PIP OP were observed in 70% of patients on radiographs and in 86% on magnetic resonance imaging, in MCP – in 45% and 66% of cases, respectively. Erosion in DIP were found in 41% of patients according to MRI and 34% as a result of X-ray examination, in PIP – in 27% and 13% of cases, in MCP – in 60% and 8% of cases, respectively. Subluxations were determined in DIP 23% on radiographs in 31% of cases by MRI, in PIP – in 8% and 6% (p&gt;0.05), in MCP subluxations almost never met – in 3% of cases by conventional radiography.</p></sec><sec><title>Conclusions</title><p>Conclusions. MRI in HOA can be used in the detection of erosive process, differential diagnosis with other diseases of the joints, determination of inflammatory changes in the hands and assessment of their severity, but has no significant advantages over standard radiography in determining the symptoms of degenerative-dystrophic nature (JSN and OP). Subluxations of the MCP joints are not typical for the HOA.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>остеоартрит суставов кисти</kwd><kwd>межфаланговые суставы</kwd><kwd>магнитно-резонансная томография</kwd><kwd>рентгенография</kwd></kwd-group><kwd-group xml:lang="en"><kwd>hand osteoarthritis</kwd><kwd>interphalangeal joints</kwd><kwd>magnetic resonance imaging</kwd><kwd>conventional radiography</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Работа выполнена за счет средств бюджетного финансирования на выполнение государственного задания по теме. Исследование выполнено в рамках научной темы № НИОКТР АААА-А19-119021190150-6 «Разработка методов комплексной терапии заболеваний костно-мышечной системы».</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Sakellariou G, Conaghan PG, Zhang W, Bijlsma JWJ, Boyesen P, D’Agostino MA, et al. EULAR recommendations for the use of imaging in the clinical management of peripheral joint osteoarthritis. Ann Rheum Dis. 2017;76(9):1484-1494. doi: 10.1136/annrheumdis-2016-210815</mixed-citation><mixed-citation xml:lang="en">Sakellariou G, Conaghan PG, Zhang W, Bijlsma JWJ, Boyesen P, D’Agostino MA, et al. EULAR recommendations for the use of imaging in the clinical management of peripheral joint osteoarthritis. 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