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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rsp</journal-id><journal-title-group><journal-title xml:lang="ru">Научно-практическая ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Rheumatology Science and Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-4484</issn><issn pub-type="epub">1995-4492</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1995-4484-2005-35</article-id><article-id custom-type="elpub" pub-id-type="custom">rsp-319</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Ранний индекс повреждения у больных системной красной волчанкой</article-title><trans-title-group xml:lang="en"><trans-title>Early damage index in systemic lupus erythematosus</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Andrianova</surname><given-names>I A</given-names></name><name name-style="western" xml:lang="en"><surname>Andrianova</surname><given-names>I A</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ivanova</surname><given-names>M M</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanova</surname><given-names>M M</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib></contrib-group><pub-date pub-type="collection"><year>2005</year></pub-date><pub-date pub-type="epub"><day>15</day><month>10</month><year>2005</year></pub-date><volume>43</volume><issue>5</issue><issue-title>№5 (2005)</issue-title><fpage>19</fpage><lpage>22</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Andrianova I.A., Ivanova M.M., 2005</copyright-statement><copyright-year>2005</copyright-year><copyright-holder xml:lang="ru">Andrianova I.A., Ivanova M.M.</copyright-holder><copyright-holder xml:lang="en">Andrianova I.A., Ivanova M.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://rsp.mediar-press.net/rsp/article/view/319">https://rsp.mediar-press.net/rsp/article/view/319</self-uri><abstract><p>Цель. Дать характеристику раннего Индекса повреждения (РИП) и обосновать целесообразность его применения для прогнозирования исхода системной красной волчанки (СКВ). Материал и методы. Основу работы составили результаты обследования и данные архивных материалов 154 больных СКВ, наблюдавшихся в Институте ревматологии РАМН с 1982 по 2001 гг. Для изучения РИП из 154 человек было отобрано 47 больных, которые впервые обследовались в Институте ревматологии РАМН в течение первых 1,5 лет от начала СКВ ("ранний период болезни"). Результаты. Выявлена высокая частота повреждения сердечно-сосудистой (27,7%) и нервной (26%) систем в течение первых 1,5 лет от начала болезни. Реже встречались повреждения костно-мышечной системы (12,8%), почек (10,6%) и глаз (8,5%). Показана роль РИП в прогнозировании исхода СКВ.</p></abstract><trans-abstract xml:lang="en"><p>Objective. To characterize early damage index (EDI) and prove its usefulness for prognosis of systemic lupus erythematosus (SLE) outcome. Material and methods. 154 SLE pts followed up at the Institute of Rheumatology (1R) of RAMS between 1982 and 2001 were included. 47 from 154 pts examined at the 1R during the first 1,5 years from the beginning of SLE ("early disease period") were selected. Results. High frequency of cardiovascular (27,7%) and nervous (26%) system damage during the first 1,5 years of the disease was revealed. Musculoskeletal (12,8%), renal (10,6%) and eye (8,5%) damage was less frequent. EDI significance for prognosis of SLE outcome was shown.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>системном красная волчанка</kwd><kwd>активность болезни</kwd><kwd>кумулятивное повреждение</kwd><kwd>Индекс повреждения</kwd><kwd>ранний Индекс повреждения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>systemic lupus erythematosus</kwd><kwd>disease activity</kwd><kwd>cumulative damage</kwd><kwd>damage index</kwd><kwd>early damage index</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">&lt;div&gt;&lt;p&gt;Иванова М.М. Прогноз заболевания и особенности лечения больных системной красной волчанкой в различных возрастных группах. Тер.архи в. 1985, 6, 125-128&lt;/p&gt;&lt;p&gt;Иванова М.М, Системная красная волчанка. Клиника, диагностика и лечение. Кпинич. ревматол., 1995, 1, 2-19&lt;/p&gt;&lt;p&gt;Насонова В.А. Системная красная волчанка (критерии диагностики и клинические варианты течения). Автореф. дисс.д.м.н. М., 1967, 38с.&lt;/p&gt;&lt;p&gt;Тарасова И.А. Значение Индекса повреждения в прогнозировании исхода системной красной волчанки. Дисс. к.м.н., М., 2003, 156 с.&lt;/p&gt;&lt;p&gt;Fortin PR., Abrahamowicz М., Neville С. et al. Impact of disease activity and cumulative damage on the health of lupus patients. Lupus, 1998,7, 101-107&lt;/p&gt;&lt;p&gt;Gladman D.D. The development and initial validation of the Systemic Lupus International Collaborating Clinics/American Collegge of Rheumatology (SL1CC/ACR) Damage Index for Systemic Lupus Erythematosus. Arthr.Rheum., 1996, 39(3), 363-369&lt;/p&gt;&lt;p&gt;Gladman D.D., Goldsmith C.H., Urowitz M.B. et al. The Systemic Lupus International Collaborating Clinics/ American Collegge of Rheumatology (SL1CC/ACR) Damage Index for Systemic Lupus Erythematosus International Comparison. J. Rheumatol., 2000, 27(2), 373-376&lt;/p&gt;&lt;p&gt;Hanly J.G. Disease activity, cumulative damage and quality of life in SLE: results of a cross-sectional study. Lupus, 1997, 6, 243-247&lt;/p&gt;&lt;p&gt;Rahman P., Gladman D.D., Urowitz M.B. elal. Early damage as measured by the SL1CC/ACR damage index is a predictor of mortality in systemic lupus erythematosus. Lupus, 2001, 10, 9396&lt;/p&gt;&lt;p&gt;Stoll Т., Stucki G., Isenberg D.A. A Damage Index for Lupus Patients - Where are we now? Lupus, 1997, 6, 219-222&lt;/p&gt;&lt;p&gt;Tan E.M., Cohen A.S., Fries J.S. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthr.Rheum., 1982, 25, 1271-1277&lt;/p&gt;&lt;p&gt;Toloza S.М., Roseman J.M., Alarcon G.S. et al. Systemic lupus erythematosus in multiethnic US cohort (LUMINA): XXII. Predictors of lime to the occurence of initial damage. Arthr.Rheum., 2004, 50(10), 3177-3186&lt;/p&gt;&lt;p&gt;Zonana-Nacach A., Barr S.G., Petri М., Magder L.S. Damage in Systemic lupus erythematosus and its association with corticosteroids. Arthr.Rheum., 2000, 43(8), 1801-1808&lt;/p&gt;&lt;/div&gt;&lt;br /&gt;</mixed-citation><mixed-citation xml:lang="en">&lt;div&gt;&lt;p&gt;Иванова М.М. Прогноз заболевания и особенности лечения больных системной красной волчанкой в различных возрастных группах. Тер.архи в. 1985, 6, 125-128&lt;/p&gt;&lt;p&gt;Иванова М.М, Системная красная волчанка. Клиника, диагностика и лечение. Кпинич. ревматол., 1995, 1, 2-19&lt;/p&gt;&lt;p&gt;Насонова В.А. Системная красная волчанка (критерии диагностики и клинические варианты течения). Автореф. дисс.д.м.н. М., 1967, 38с.&lt;/p&gt;&lt;p&gt;Тарасова И.А. Значение Индекса повреждения в прогнозировании исхода системной красной волчанки. Дисс. к.м.н., М., 2003, 156 с.&lt;/p&gt;&lt;p&gt;Fortin PR., Abrahamowicz М., Neville С. et al. Impact of disease activity and cumulative damage on the health of lupus patients. Lupus, 1998,7, 101-107&lt;/p&gt;&lt;p&gt;Gladman D.D. The development and initial validation of the Systemic Lupus International Collaborating Clinics/American Collegge of Rheumatology (SL1CC/ACR) Damage Index for Systemic Lupus Erythematosus. Arthr.Rheum., 1996, 39(3), 363-369&lt;/p&gt;&lt;p&gt;Gladman D.D., Goldsmith C.H., Urowitz M.B. et al. The Systemic Lupus International Collaborating Clinics/ American Collegge of Rheumatology (SL1CC/ACR) Damage Index for Systemic Lupus Erythematosus International Comparison. J. Rheumatol., 2000, 27(2), 373-376&lt;/p&gt;&lt;p&gt;Hanly J.G. Disease activity, cumulative damage and quality of life in SLE: results of a cross-sectional study. Lupus, 1997, 6, 243-247&lt;/p&gt;&lt;p&gt;Rahman P., Gladman D.D., Urowitz M.B. elal. Early damage as measured by the SL1CC/ACR damage index is a predictor of mortality in systemic lupus erythematosus. Lupus, 2001, 10, 9396&lt;/p&gt;&lt;p&gt;Stoll Т., Stucki G., Isenberg D.A. A Damage Index for Lupus Patients - Where are we now? Lupus, 1997, 6, 219-222&lt;/p&gt;&lt;p&gt;Tan E.M., Cohen A.S., Fries J.S. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthr.Rheum., 1982, 25, 1271-1277&lt;/p&gt;&lt;p&gt;Toloza S.М., Roseman J.M., Alarcon G.S. et al. Systemic lupus erythematosus in multiethnic US cohort (LUMINA): XXII. Predictors of lime to the occurence of initial damage. Arthr.Rheum., 2004, 50(10), 3177-3186&lt;/p&gt;&lt;p&gt;Zonana-Nacach A., Barr S.G., Petri М., Magder L.S. Damage in Systemic lupus erythematosus and its association with corticosteroids. Arthr.Rheum., 2000, 43(8), 1801-1808&lt;/p&gt;&lt;/div&gt;&lt;br /&gt;</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
