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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rsp</journal-id><journal-title-group><journal-title xml:lang="ru">Научно-практическая ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Rheumatology Science and Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-4484</issn><issn pub-type="epub">1995-4492</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.47360/1995-4484-2022-566-572</article-id><article-id custom-type="elpub" pub-id-type="custom">rsp-3224</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>Нутритивный статус у больных ревматоидным артритом: есть ли связь с саркопеническим фенотипом состава тела?</article-title><trans-title-group xml:lang="en"><trans-title>Nutritional status in patients with rheumatoid arthritis: is there an association with the sarcopenic phenotype of body composition?</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2809-0197</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Добровольская</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Dobrovolskaya</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34а</p></bio><bio xml:lang="en"><p>115522, Moscow, Kashirskoye Highway, 34A</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0961-9785</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Демин</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Demin</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34а</p></bio><bio xml:lang="en"><p>115522, Moscow, Kashirskoye Highway, 34A</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6759-8367</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никитинская</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikitinskaya</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34а</p></bio><bio xml:lang="en"><p>115522, Moscow, Kashirskoye Highway, 34A</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4739-4302</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Торопцова</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Toroptsova</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34а</p></bio><bio xml:lang="en"><p>115522, Moscow, Kashirskoye Highway, 34A</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7661-3124</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Феклистов</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Feklistov</surname><given-names>A. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34а</p></bio><bio xml:lang="en"><p>115522, Moscow, Kashirskoye Highway, 34A</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт ревматологии&#13;
им. В.А. Насоновой»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.A. Nasonova Research Institute of Rheumatology</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>11</day><month>11</month><year>2022</year></pub-date><volume>60</volume><issue>5</issue><fpage>566</fpage><lpage>572</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Добровольская О.В., Демин Н.В., Никитинская О.А., Торопцова Н.В., Феклистов А.Ю., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Добровольская О.В., Демин Н.В., Никитинская О.А., Торопцова Н.В., Феклистов А.Ю.</copyright-holder><copyright-holder xml:lang="en">Dobrovolskaya O.V., Demin N.V., Nikitinskaya O.A., Toroptsova N.V., Feklistov A.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://rsp.mediar-press.net/rsp/article/view/3224">https://rsp.mediar-press.net/rsp/article/view/3224</self-uri><abstract><p>Цель исследования – оценить нутритивный статус и его связь с саркопеническим фенотипом состава тела у женщин с ревматоидным артритом (РА).</p><sec><title>Материал и методы</title><p>Материал и методы. В одномоментное исследование включена 91 женщина в возрасте от 40 до 75 лет с достоверным РА по критериям Американской коллегии ревматологов/Европейского альянса ревматологических ассоциаций (ACR/EULAR, American College of Rheumatology/European Alliance of Associations for Rheumatology) 2010 г. и длительностью заболевания не менее 1 года. Проведено анкетирование, лабораторное и денситометрическое обследование. Нутритивный статус оценивали с помощью опросника MNA (Mini Nutricial Assessment).</p></sec><sec><title>Результаты</title><p>Результаты. Вероятная мальнутриция и мальнутриция по опроснику MNA выявлены у 44,0% больных РА. Эти пациенты отличались от лиц с нормальным нутритивным статусом более высоким риском остеопоротических переломов шейки бедра (р=0,035), меньшей аппендикулярной мышечной массой (р=0,048) и более низкой оценкой состояния здоровья (р=0,012). В зависимости от наличия саркопенического фенотипа женщины статистически значимо различались по нутритивному статусу по MNA, суточному потреблению кальция с пищей, окружности плеча, голени, талии и бедер. Многофакторный регрессионный анализ показал, что саркопенический фенотип ассоциировался со счетом менее 24 по MNA (отношение шансов (ОШ) – 6,14; р=0,036), суточным потреблением кальция с пищей менее 500 мг (ОШ=9,55; р=0,007) и окружностью плеча недоминантной руки менее 25 см (ОШ=9,32; р=0,015).</p></sec><sec><title>Заключение</title><p>Заключение. Недостаточность питания встречалась почти у половины пациентов с РА. Сниженный нутритивный статус по опроснику MNA, низкое потребление кальция с продуктами питания и окружность плеча недоминантной руки менее 25 см повышали риск наличия саркопенического фенотипа у женщин с РА.</p></sec></abstract><trans-abstract xml:lang="en"><p>Aim – to evaluate the nutritional status and its relationship with the sarcopenic phenotype of body composition in women with rheumatoid arthritis (RA).</p><sec><title>Material and methods</title><p>Material and methods. The study included 91 women aged 40 to 75 years with RA according to ACR/EULAR criteria (2010) and a disease duration of at least 1 year. A questionnaire, laboratory and densitometric examination were conducted. Nutritional status was assessed using a MNA (Mini Nutricial Assessment) questionnaire.</p></sec><sec><title>Results</title><p>Results. Malnutrition and at risk of malnutrition according to the MNA were detected in 44.0% of patients with RA. These patients differed from those with normal nutritional status with a higher risk of osteoporotic hip fractures according to FRAX (p=0.035), lower appendicular muscle mass (AMM) (p=0.048) and lower self-assessment of health status (p=0.012). Patients significantly differed in nutritional status according to MNA, daily intake of calcium with food, circumferences of the mid-upper arm, calf, waist and hips, depending on the presence of sarcopenic phenotype. Multivariate regression analysis showed that the sarcopenic phenotype was associated with a nutritional status according to MNA less than 24 points (odds ratio (OR) – 6.14; p=0.036), daily calcium intake less than 500 mg (OR=9.55; p=0.007) and mid-upper arm circumference less than 25 cm (OR=9.32; p=0.015).</p></sec><sec><title>Conclusion</title><p>Conclusion. Malnutrition was found in almost half of the patients with RA. It was revealed that a low nutritional status according to the MNA, low calcium intake and mid-upper arm circumference less than 25 cm increased the risk of having a sarcopenic phenotype in women with RA.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>ревматоидный артрит</kwd><kwd>саркопения</kwd><kwd>состав тела</kwd><kwd>статус питания</kwd><kwd>потребление кальция</kwd></kwd-group><kwd-group xml:lang="en"><kwd>rheumatoid arthritis</kwd><kwd>sarcopenia</kwd><kwd>body composition</kwd><kwd>nutritional status</kwd><kwd>calcium intake</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">dos Santos AT, Assunção A, Foschetti DA, Nataniel F, Uchôa M, Alves N, et al. Assessment of nutritional and biochemical status in patients with rheumatoid arthritis undergoing pharmacological treatment. A pilot study. 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