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<article article-type="editorial" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rsp</journal-id><journal-title-group><journal-title xml:lang="ru">Научно-практическая ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Rheumatology Science and Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-4484</issn><issn pub-type="epub">1995-4492</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">rsp-3231</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Проблемы терапии ревматоидного артрита и перспективы применения ингибитора ИЛ-1 (Анакинра). (Резолюция Экспертного Совета, 19 мая 2022 г.)</article-title><trans-title-group xml:lang="en"><trans-title>Problems in the treatment of rheumatoid arthritis and prospects for the use of an IL-1 inhibitor (Anakinra). (Resolution of the Expert Council, May 19, 2022)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Редакционная</surname><given-names>статья</given-names></name><name name-style="western" xml:lang="en"><surname>Editorial</surname><given-names>Article</given-names></name></name-alternatives></contrib></contrib-group><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>11</day><month>11</month><year>2022</year></pub-date><volume>60</volume><issue>5</issue><fpage>609</fpage><lpage>611</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Редакционная с., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Редакционная с.</copyright-holder><copyright-holder xml:lang="en">Editorial a.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://rsp.mediar-press.net/rsp/article/view/3231">https://rsp.mediar-press.net/rsp/article/view/3231</self-uri><abstract><p>.</p></abstract><trans-abstract xml:lang="en"><p>.</p></trans-abstract></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Cvetkovic RS, Keating G. Anakinra. BioDrugs. 2002;16(4): 303–311; discussion 313–314. doi: 10.2165/00063030- 200216040-00005</mixed-citation><mixed-citation xml:lang="en">Cvetkovic RS, Keating G. Anakinra. BioDrugs. 2002;16(4): 303–311; discussion 313–314. doi: 10.2165/00063030- 200216040-00005</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Bresnihan B, Alvaro-Gracia JM, Cobby M, Doherty M, Domljan Z, et al. Treatment of rheumatoid arthritis with recombinant human interleukin-1 receptor antagonist. Arthritis Rheum. 1998;41(12):2196–204. doi: 10.1002/1529-0131</mixed-citation><mixed-citation xml:lang="en">Bresnihan B, Alvaro-Gracia JM, Cobby M, Doherty M, Domljan Z, et al. Treatment of rheumatoid arthritis with recombinant human interleukin-1 receptor antagonist. Arthritis Rheum. 1998;41(12):2196–204. doi: 10.1002/1529-0131</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Cohen S, Hurd E, Cush J, Schiff M, Weinblatt ME, et al. Treatment of rheumatoid arthritis with anakinra, a recombinant human interleukin-1 receptor antagonist, in combination with methotrexate: results of a twenty-four-week, multicenter, randomized, double-blind, placebo-controlled trial. Arthritis Rheum. 2002;46(3): 614–624. doi: 10.1002/art.10141</mixed-citation><mixed-citation xml:lang="en">Cohen S, Hurd E, Cush J, Schiff M, Weinblatt ME, et al. Treatment of rheumatoid arthritis with anakinra, a recombinant human interleukin-1 receptor antagonist, in combination with methotrexate: results of a twenty-four-week, multicenter, randomized, double-blind, placebo-controlled trial. Arthritis Rheum. 2002;46(3): 614–624. doi: 10.1002/art.10141</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Cohen SB, Moreland LW, Cush JJ, Greenwald MW, Block S, et al.; 990145 Study Group. A multicentre, double blind, randomised, placebo controlled trial of anakinra (Kineret), a recombinant interleukin 1 receptor antagonist, in patients with rheumatoid arthritis treated with background methotrexate. Ann Rheum Dis. 2004;63(9):1062–1068. doi: 10.1136/ard.2003.016014.</mixed-citation><mixed-citation xml:lang="en">Cohen SB, Moreland LW, Cush JJ, Greenwald MW, Block S, et al.; 990145 Study Group. A multicentre, double blind, randomised, placebo controlled trial of anakinra (Kineret), a recombinant interleukin 1 receptor antagonist, in patients with rheumatoid arthritis treated with background methotrexate. Ann Rheum Dis. 2004;63(9):1062–1068. doi: 10.1136/ard.2003.016014.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Fleischmann RM, Schechtman J, Bennett R, Handel ML, Burmester GR, et al. Anakinra, a recombinant human interleukin-1 receptor antagonist (r-metHuIL-1ra), in patients with rheumatoid arthritis: A large, international, multicenter, placebo-controlled trial. Arthritis Rheum. 2003;48(4):927–934. doi: 10.1002/art.10870</mixed-citation><mixed-citation xml:lang="en">Fleischmann RM, Schechtman J, Bennett R, Handel ML, Burmester GR, et al. Anakinra, a recombinant human interleukin-1 receptor antagonist (r-metHuIL-1ra), in patients with rheumatoid arthritis: A large, international, multicenter, placebo-controlled trial. Arthritis Rheum. 2003;48(4):927–934. doi: 10.1002/art.10870</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Nuki G, Bresnihan B, Bear MB, McCabe D; European Group Of Clinical Investigators. Long-term safety and maintenance of clinical improvement following treatment with anakinra (recombinant human interleukin-1 receptor antagonist) in patients with rheumatoid arthritis: extension phase of a randomized, double-blind, placebo-controlled trial. Arthritis Rheum. 2002;46(11):2838–2846. doi: 10.1002/art.10578</mixed-citation><mixed-citation xml:lang="en">Nuki G, Bresnihan B, Bear MB, McCabe D; European Group Of Clinical Investigators. Long-term safety and maintenance of clinical improvement following treatment with anakinra (recombinant human interleukin-1 receptor antagonist) in patients with rheumatoid arthritis: extension phase of a randomized, double-blind, placebo-controlled trial. Arthritis Rheum. 2002;46(11):2838–2846. doi: 10.1002/art.10578</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Cohen SB, Moreland LW, Cush JJ, Greenwald MW, Block S, et al.; 990145 Study Group. A multicentre, double blind, randomised, placebo controlled trial of anakinra (Kineret), a recombinant interleukin 1 receptor antagonist, in patients with rheumatoid arthritis treated with background methotrexate. Ann Rheum Dis. 2004;63(9): 1062–1068. doi: 10.1136/ard.2003.016014</mixed-citation><mixed-citation xml:lang="en">Cohen SB, Moreland LW, Cush JJ, Greenwald MW, Block S, et al.; 990145 Study Group. A multicentre, double blind, randomised, placebo controlled trial of anakinra (Kineret), a recombinant interleukin 1 receptor antagonist, in patients with rheumatoid arthritis treated with background methotrexate. Ann Rheum Dis. 2004;63(9): 1062–1068. doi: 10.1136/ard.2003.016014</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Schiff MH, DiVittorio G, Tesser J, Fleischmann R, Schechtman J, Hartman S, et al. The safety of anakinra in high-risk patients with acti ve rheumatoid arthritis: six-month observations of patients with comorbid conditions. Arthritis Rheum. 2004;50(6):1752–1760. doi: 10.1002/art.20277</mixed-citation><mixed-citation xml:lang="en">Schiff MH, DiVittorio G, Tesser J, Fleischmann R, Schechtman J, Hartman S, et al. The safety of anakinra in high-risk patients with acti ve rheumatoid arthritis: six-month observations of patients with comorbid conditions. Arthritis Rheum. 2004;50(6):1752–1760. doi: 10.1002/art.20277</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Fleischmann RM, Tesser J, Schiff MH, Schechtman J, Burmester GR, et al. Safety of extended treatment with anakinra in patients with rheumatoid arthritis. Ann Rheum Dis. 2006;65(8):1006–1012. doi: 10.1136/ard.2005.048371</mixed-citation><mixed-citation xml:lang="en">Fleischmann RM, Tesser J, Schiff MH, Schechtman J, Burmester GR, et al. Safety of extended treatment with anakinra in patients with rheumatoid arthritis. Ann Rheum Dis. 2006;65(8):1006–1012. doi: 10.1136/ard.2005.048371</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Mertens M, Singh JA. Anakinra for rheumatoid arthritis: a systematic review. J Rheumatol. 2009;36:1118–11125. doi: 10.3899/ jrheum.090074</mixed-citation><mixed-citation xml:lang="en">Mertens M, Singh JA. Anakinra for rheumatoid arthritis: a systematic review. J Rheumatol. 2009;36:1118–11125. doi: 10.3899/ jrheum.090074</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Bedaiwi MK, Almaghlouth I, Omair MA. Effectiveness and adverse effects of anakinra in treatment of rheumatoid arthritis: a systematic review. Eur Rev Med Pharmacol Sci. 2021;25(24):7833–7839. doi: 10.26355/eurrev_202112_27630</mixed-citation><mixed-citation xml:lang="en">Bedaiwi MK, Almaghlouth I, Omair MA. Effectiveness and adverse effects of anakinra in treatment of rheumatoid arthritis: a systematic review. Eur Rev Med Pharmacol Sci. 2021;25(24):7833–7839. doi: 10.26355/eurrev_202112_27630</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Nam JL, Ramino S, Gaujoux-Viala C, et al. Extended report: Efficacy of biological disease-modifying antirheumatic drugs: a systematic literature review informing the 2013 update of the EULAR recommendations for the management of rheumatoid arthritis. Ann Rheum Dis. 2014;73:516–528. doi: 10.1136/annrheumdis2013-204577</mixed-citation><mixed-citation xml:lang="en">Nam JL, Ramino S, Gaujoux-Viala C, et al. Extended report: Efficacy of biological disease-modifying antirheumatic drugs: a systematic literature review informing the 2013 update of the EULAR recommendations for the management of rheumatoid arthritis. Ann Rheum Dis. 2014;73:516–528. doi: 10.1136/annrheumdis2013-204577</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Singh JA, Christensen R, Wells GA, et al. Biologics for rheumatoid arthritis: an overview of Cochrane reviews (Protocol). Cochrane Database of Systematic Reviews. 2009;2:CD007848. doi: 10.1002/14651858.CD007848</mixed-citation><mixed-citation xml:lang="en">Singh JA, Christensen R, Wells GA, et al. Biologics for rheumatoid arthritis: an overview of Cochrane reviews (Protocol). Cochrane Database of Systematic Reviews. 2009;2:CD007848. doi: 10.1002/14651858.CD007848</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Nikfar S, Saiyarsarai P, Tigabu BM, Abdollahi M. Efficacy and safety of interleukin-1 antagonists in rheumatoid arthritis: a systematic review and meta-analysis. Rheumatol Int. 2018;38(8):1363–1383. doi: 10.1007/s00296-018-4041-1</mixed-citation><mixed-citation xml:lang="en">Nikfar S, Saiyarsarai P, Tigabu BM, Abdollahi M. Efficacy and safety of interleukin-1 antagonists in rheumatoid arthritis: a systematic review and meta-analysis. Rheumatol Int. 2018;38(8):1363–1383. doi: 10.1007/s00296-018-4041-1</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Насонов Е.Л., Самсонов М.Ю. Роль интерлейкина-1 в развитии заболеваний человека: фокус на анакинре (рецепторном антагонисте ИЛ-1). Научно-практическая ревматология. 2022;60(3):280–298.</mixed-citation><mixed-citation xml:lang="en">Nasonov EL, Samsonov MYu. The role of interleukin 1 in the development of human diseases: focus on Anakinra (IL-1 receptor antagonist). Rheumatology Science and Practice. 2022;60(3):280–298 (In Russ.). doi: 10.47360/1995-4484- 2022-280-298</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Doria A, Zen M, Bettio S, Gatto M, Bassi N, et al. Autoinflammation and autoimmunity: bridging the divide. Autoimmun Rev. 2012;12(1):22–30. doi: 10.1016/j.autrev.2012.07.018</mixed-citation><mixed-citation xml:lang="en">Doria A, Zen M, Bettio S, Gatto M, Bassi N, et al. Autoinflammation and autoimmunity: bridging the divide. Autoimmun Rev. 2012;12(1):22–30. doi: 10.1016/j.autrev.2012.07.018</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Smolen JS, Aletaha D, McInnes IB. Rheumatoid arthritis. Lancet. 2016;388(10055):2023–38. doi: 10.1016/S0140-6736(16)30173-8</mixed-citation><mixed-citation xml:lang="en">Smolen JS, Aletaha D, McInnes IB. Rheumatoid arthritis. Lancet. 2016;388(10055):2023–38. doi: 10.1016/S0140-6736(16)30173-8</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Smolen JS, Aletaha D, Bijlsma JW, Breedveld FC, Boumpas D, et al.; T2T Expert Committee. Treating rheumatoid ar thritis to target: recommendations of an international task force. Ann Rheum Dis. 2010;69(4):631–637. doi: 10.1136/ard.2009.123919</mixed-citation><mixed-citation xml:lang="en">Smolen JS, Aletaha D, Bijlsma JW, Breedveld FC, Boumpas D, et al.; T2T Expert Committee. Treating rheumatoid ar thritis to target: recommendations of an international task force. Ann Rheum Dis. 2010;69(4):631–637. doi: 10.1136/ard.2009.123919</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Smolen JS, Landewé RBM, Bijlsma JWJ, Burmester GR, Dougados M, et al. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2019 update. Ann Rheum Dis. 2020;79(6):685–699. doi: 10.1136/annrheumdis-2019-216655</mixed-citation><mixed-citation xml:lang="en">Smolen JS, Landewé RBM, Bijlsma JWJ, Burmester GR, Dougados M, et al. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2019 update. Ann Rheum Dis. 2020;79(6):685–699. doi: 10.1136/annrheumdis-2019-216655</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Насонов ЕЛ, Олюнин ЮА, Лила АМ. Ревматоидный артрит: проблемы ремиссии и резистентности к терапии. Научно-практическая ревматология. 2018;56(3):263–271.</mixed-citation><mixed-citation xml:lang="en">Nasonov EL, Olyunin YuA, Lila AM. RHEUMATOID ARTHRITIS: THE PROBLEMS OF REMISSION AND THERAPY RESISTANCE. Rheumatology Science and Practice. 2018;56(3):263–271 (In Russ.) doi: 10.14412/1995-4484-2018-263-271</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Nagy G, Roodenrijs NMT, Welsing PM, Kedves M, Hamar A, et al. EULAR definition of difficult-to-treat rheumatoid arthritis. Ann Rheum Dis. 2021;80(1):31–35. doi: 10.1136/annrheumdis-2020-217344</mixed-citation><mixed-citation xml:lang="en">Nagy G, Roodenrijs NMT, Welsing PM, Kedves M, Hamar A, et al. EULAR definition of difficult-to-treat rheumatoid arthritis. Ann Rheum Dis. 2021;80(1):31–35. doi: 10.1136/annrheumdis-2020-217344</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Nagy G, Roodenrijs NMT, Welsing PMJ, Kedves M, Hamar A, et al. EULAR points to consider for the management of difficultto-treat rheumatoid arthritis. Ann Rheum Dis. 2022;81(1):20–33. doi: 10.1136/annrheumdis-2021-220973</mixed-citation><mixed-citation xml:lang="en">Nagy G, Roodenrijs NMT, Welsing PMJ, Kedves M, Hamar A, et al. EULAR points to consider for the management of difficultto-treat rheumatoid arthritis. Ann Rheum Dis. 2022;81(1):20–33. doi: 10.1136/annrheumdis-2021-220973</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Tan Y, Buch MH. ‘Difficult to treat’ rheumatoid arthritis: current position and considerations for next steps. RMD Open. 2022;8(2):e002387. doi: 10.1136/rmdopen-2022-002387</mixed-citation><mixed-citation xml:lang="en">Tan Y, Buch MH. ‘Difficult to treat’ rheumatoid arthritis: current position and considerations for next steps. RMD Open. 2022;8(2):e002387. doi: 10.1136/rmdopen-2022-002387</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">McGonagle D, Watad A, Savic S. Mechanistic immunological based classification of rheumatoid arthritis. Autoimmun Rev. 2018;17(11):1115–1123. doi: 10.1016/j.autrev.2018.06.001</mixed-citation><mixed-citation xml:lang="en">McGonagle D, Watad A, Savic S. Mechanistic immunological based classification of rheumatoid arthritis. Autoimmun Rev. 2018;17(11):1115–1123. doi: 10.1016/j.autrev.2018.06.001</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Atzeni F, Rodríguez-Carrio J, Popa CD, Nurmohamed MT, Szűcs G, Szekanecz Z. Cardiovascular effects of approved drugs for rheumatoid arthritis. Nat Rev Rheumatol. 2021;17(5):270–290. doi: 10.1038/s41584-021-00593-3</mixed-citation><mixed-citation xml:lang="en">Atzeni F, Rodríguez-Carrio J, Popa CD, Nurmohamed MT, Szűcs G, Szekanecz Z. Cardiovascular effects of approved drugs for rheumatoid arthritis. Nat Rev Rheumatol. 2021;17(5):270–290. doi: 10.1038/s41584-021-00593-3</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Tian Z, Mclaughlin J, Verma A, Chinoy H, Heald AH. The relationship between rheumatoid arthritis and diabetes mellitus: a systematic review and meta-analysis. Cardiovasc Endocrinol Metab. 2021;10(2):125–131. doi: 10.1097/XCE.0000000000000244</mixed-citation><mixed-citation xml:lang="en">Tian Z, Mclaughlin J, Verma A, Chinoy H, Heald AH. The relationship between rheumatoid arthritis and diabetes mellitus: a systematic review and meta-analysis. Cardiovasc Endocrinol Metab. 2021;10(2):125–131. doi: 10.1097/XCE.0000000000000244</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Baker JF, England BR, George M. Disease activity, cytokines, chemokines and the risk of incident diabetes in rheumatoid arthritis, Ann Rheum Dis. 2021;72:annrheumdis-2020-2019140.</mixed-citation><mixed-citation xml:lang="en">Baker JF, England BR, George M. Disease activity, cytokines, chemokines and the risk of incident diabetes in rheumatoid arthritis, Ann Rheum Dis. 2021;72:annrheumdis-2020-2019140.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Ruscitti P, Masedu F, Alvaro S, Airò P, Battafarano N, et al. Antiinterleukin-1 treatment in patients with rheumatoid arthritis and type 2 diabetes (TRACK): A multicentre, open-label, randomised controlled trial. PLoS Med. 2019;16(9):e1002901. doi: 10.1371/journal.pmed.1002901</mixed-citation><mixed-citation xml:lang="en">Ruscitti P, Masedu F, Alvaro S, Airò P, Battafarano N, et al. Antiinterleukin-1 treatment in patients with rheumatoid arthritis and type 2 diabetes (TRACK): A multicentre, open-label, randomised controlled trial. PLoS Med. 2019;16(9):e1002901. doi: 10.1371/journal.pmed.1002901</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Ruscitti P, Berardicurti O, Cipriani P, Giacomelli R; TRACK study group. Benefits of anakinra versus TNF inhibitors in rheumatoid arthritis and type 2 diabetes: long-term findings from participants furtherly followed-up in the TRACK study, a multicentre, open-label, randomised, controlled trial. Clin Exp Rheumatol. 2021;39(2):403–406.</mixed-citation><mixed-citation xml:lang="en">Ruscitti P, Berardicurti O, Cipriani P, Giacomelli R; TRACK study group. Benefits of anakinra versus TNF inhibitors in rheumatoid arthritis and type 2 diabetes: long-term findings from participants furtherly followed-up in the TRACK study, a multicentre, open-label, randomised, controlled trial. Clin Exp Rheumatol. 2021;39(2):403–406.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Ruscitti P, Ursini F, Cipriani P, Greco M, Alvaro S, et al. IL-1 inhibition improves insulin resistance and adipokines in rheumatoid arthritis patients with comorbid type 2 diabetes: An observational study. Medicine (Baltimore). 2019;98(7):e14587. doi: 10.1097/MD.0000000000014587</mixed-citation><mixed-citation xml:lang="en">Ruscitti P, Ursini F, Cipriani P, Greco M, Alvaro S, et al. IL-1 inhibition improves insulin resistance and adipokines in rheumatoid arthritis patients with comorbid type 2 diabetes: An observational study. Medicine (Baltimore). 2019;98(7):e14587. doi: 10.1097/MD.0000000000014587</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Khalid Y, Dasu N, Shah A, Brown K, Kaell A, et al. Incidence of congestive heart failure in rheumatoid arthritis: a review of literature and meta-regression analysis. ESC Heart Fail. 2020;7(6): 3745–3753. doi: 10.1002/ehf2.12947</mixed-citation><mixed-citation xml:lang="en">Khalid Y, Dasu N, Shah A, Brown K, Kaell A, et al. Incidence of congestive heart failure in rheumatoid arthritis: a review of literature and meta-regression analysis. ESC Heart Fail. 2020;7(6): 3745–3753. doi: 10.1002/ehf2.12947</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Ikonomidis I, Lekakis JP, Nikolaou M, Paraskevaidis I, Andreadou I, et al. Inhibition of interleukin-1 by anakinra improves vascular and left ventricular function in patients with rheumatoid arthritis. Circulation. 2008;117(20):2662–2669. doi: 10.1161/CIRCULATIONAHA.107.731877</mixed-citation><mixed-citation xml:lang="en">Ikonomidis I, Lekakis JP, Nikolaou M, Paraskevaidis I, Andreadou I, et al. Inhibition of interleukin-1 by anakinra improves vascular and left ventricular function in patients with rheumatoid arthritis. Circulation. 2008;117(20):2662–2669. doi: 10.1161/CIRCULATIONAHA.107.731877</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Ikonomidis I, Tzortzis S, Andreadou I, Paraskevaidis I, Katseli C, et al. Increased benefit of interleukin-1 inhibition on vascular function, myocardial deformation, and twisting in patients with coronary artery disease and coexisting rheumatoid arthritis. Circ Cardiovasc Imaging. 2014;7(4):619–628. doi: 10.1161/CIRCIMAGING.113.001193</mixed-citation><mixed-citation xml:lang="en">Ikonomidis I, Tzortzis S, Andreadou I, Paraskevaidis I, Katseli C, et al. Increased benefit of interleukin-1 inhibition on vascular function, myocardial deformation, and twisting in patients with coronary artery disease and coexisting rheumatoid arthritis. Circ Cardiovasc Imaging. 2014;7(4):619–628. doi: 10.1161/CIRCIMAGING.113.001193</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Almeida-Santiago, C., Quevedo-Abeledo, J.C., Hernández-Hernández, V. et al. Interleukin 1 receptor antagonist relation to cardiovascular disease risk in patients with rheumatoid arthritis. Sci Rep 12, 13698 (2022). doi: 10.1038/s41598-022-18128-5</mixed-citation><mixed-citation xml:lang="en">Almeida-Santiago, C., Quevedo-Abeledo, J.C., HernándezHernández, V. et al. Interleukin 1 receptor antagonist relation to cardiovascular disease risk in patients with rheumatoid arthritis. Sci Rep 12, 13698 (2022). doi: 10.1038/s41598-022-18128-5</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Setoguchi S, Schneeweiss S, Avorn J, Katz JN, Weinblatt ME, Levin R, Solomon DH. Tumor necrosis factor-alpha antagonist use and heart failure in elderly patients with rheumatoid arthritis. Am Heart J. 2008;156(2):336–341. doi: 10.1016/j.ahj.2008.02.025</mixed-citation><mixed-citation xml:lang="en">Setoguchi S, Schneeweiss S, Avorn J, Katz JN, Weinblatt ME, Levin R, Solomon DH. Tumor necrosis factor-alpha antagonist use and heart failure in elderly patients with rheumatoid arthritis. Am Heart J. 2008;156(2):336–341. doi: 10.1016/j.ahj.2008.02.025</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Fraenkel L, Bathon JM, England BR, St Clair EW, Arayssi T, et al. 2021 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis. Arthritis Rheumatol. 2021;73(7):1108–1123. doi: 10.1002/art.41752</mixed-citation><mixed-citation xml:lang="en">Fraenkel L, Bathon JM, England BR, St Clair EW, Arayssi T, et al. 2021 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis. Arthritis Rheumatol. 2021;73(7):1108–1123. doi: 10.1002/art.41752</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Kontzias A, Barkhodari A, Yao Q. Pericarditis in Systemic Rheumatologic Diseases. Curr Cardiol Rep. 2020;22(11):142. doi: 10.1007/s11886-020-01415-w</mixed-citation><mixed-citation xml:lang="en">Kontzias A, Barkhodari A, Yao Q. Pericarditis in Systemic Rheumatologic Diseases. Curr Cardiol Rep. 2020;22(11):142. doi: 10.1007/s11886-020-01415-w</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Correia ETO, Dos Santos Barbetta LM, de Almeida JPCL, Mesquita ET. Anakinra in Recurrent Pericarditis: Current Evidence on Clinical Use, Effectiveness, and Safety. J Cardiovasc Pharmacol. 2020;76(1):42–49. doi: 10.1097/FJC.0000000000000839</mixed-citation><mixed-citation xml:lang="en">Correia ETO, Dos Santos Barbetta LM, de Almeida JPCL, Mesquita ET. Anakinra in Recurrent Pericarditis: Current Evidence on Clinical Use, Effectiveness, and Safety. J Cardiovasc Pharmacol. 2020;76(1):42–49. doi: 10.1097/FJC.0000000000000839</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
