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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rsp</journal-id><journal-title-group><journal-title xml:lang="ru">Научно-практическая ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Rheumatology Science and Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-4484</issn><issn pub-type="epub">1995-4492</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.47360/1995-4484-2022-587-59</article-id><article-id custom-type="elpub" pub-id-type="custom">rsp-3248</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS AND LECTURES</subject></subj-group></article-categories><title-group><article-title>Трабекулярный костный индекс при ревматических заболеваниях</article-title><trans-title-group xml:lang="en"><trans-title>Trabecular bone score in rheumatic disease</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0560-3495</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Козырева</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kozyreva</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34а</p></bio><bio xml:lang="en"><p>115522, Moscow, Kashirskoye Highway, 34A</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6759-8367</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никитинская</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikitinskaya</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34а</p></bio><bio xml:lang="en"><p>115522, Moscow, Kashirskoye Highway, 34A</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4739-4302</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Торопцова</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Toroptsova</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Торопцова Наталья Владимировна</p><p>115522, Москва, Каширское шоссе, 34а</p></bio><bio xml:lang="en"><p>Natalia Toroptsova</p><p>115522, Moscow, Kashirskoye Highway, 34A</p></bio><email xlink:type="simple">torop@irramn.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.A. Nasonova Research Institute of Rheumatology</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>25</day><month>12</month><year>2022</year></pub-date><volume>60</volume><issue>6</issue><fpage>587</fpage><lpage>593</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Козырева М.В., Никитинская О.А., Торопцова Н.В., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Козырева М.В., Никитинская О.А., Торопцова Н.В.</copyright-holder><copyright-holder xml:lang="en">Kozyreva M.V., Nikitinskaya O.A., Toroptsova N.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://rsp.mediar-press.net/rsp/article/view/3248">https://rsp.mediar-press.net/rsp/article/view/3248</self-uri><abstract><p>Пациенты с иммуновоспалительными ревматическими заболеваниями (ИВРЗ) имеют высокий риск развития остеопороза (ОП) и остеопоротических переломов. Трабекулярный костный индекс (ТКИ) является относительно новым показателем качества кости, который независимо от минеральной плотности кости (МПК) определяет риск перелома. В исследованиях, посвященных изучению ТКИ, показано, что у пациентов с ИВРЗ его значения ниже, чем у здоровых лиц; при этом полученные данные свидетельствуют о том, что данный индекс при ряде ИВРЗ и особенно у пациентов, получающих глюкокортикоиды, позволяет прогнозировать переломы точнее, чем МПК или калькулятор оценки 10-летней вероятности остеопоротических переломов FRAX (Fracture Risk Assessment Tool). В немногочисленных исследованиях также отмечалось, что снижение ТКИ у пациентов с ревматоидным артритом, системной склеродермией и анкилозирующим спондилитом было связано с активностью заболевания. Однако в литературе мало данных о влиянии как терапии ИВРЗ, так и лечения ОП на величину ТКИ и прогнозирование переломов при этих заболеваниях. </p></abstract><trans-abstract xml:lang="en"><p>Patients with rheumatic diseases (RD) are at high risk of osteoporosis (OP) and osteoporotic fractures. The Trabecular bone score (TBS) is a relatively novel method of assessing bone quality, which independently predicts fracture risk regardless of bone mineral density (BMD). A lower TBS in patients with RD compared to controls is shown in most studies concerning TBS and RD. The data obtained indicate that TBS predicts fractures better in RD, especially in patients receiving glucocorticoids, than BMD or the FRAX algorithm. TBS degradation has been associated with disease activity in ankylosing spondylitis, systemic sclerosis, and rheumatoid arthritis in a few studies. However, there is little data in the literature on the effect of rheumatic disease therapy and OP treatment in patients with RD on predictive ability of TBS for incident fracture.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>трабекулярный костный индекс</kwd><kwd>риск переломов</kwd><kwd>ревматические заболевания</kwd><kwd>ревматоидный артрит</kwd><kwd>системная склеродермия</kwd><kwd>глюкокортикоиды</kwd></kwd-group><kwd-group xml:lang="en"><kwd>trabecular bone score</kwd><kwd>fracture risk assessment</kwd><kwd>rheumatic disease</kwd><kwd>rheumatoid arthritis</kwd><kwd>systemic sclerosis</kwd><kwd>glucocorticoids</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Работа выполнена в рамках научно-исследовательской работы № 1021051403074-2.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Rotta D, Fassio A, Rossini M, Giollo A, Viapiana O, Orsolini G, et al. 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