<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rsp</journal-id><journal-title-group><journal-title xml:lang="ru">Научно-практическая ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Rheumatology Science and Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-4484</issn><issn pub-type="epub">1995-4492</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.47360/1995-4484-2023-763-768</article-id><article-id custom-type="elpub" pub-id-type="custom">rsp-3476</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЙ СЛУЧАЙ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL OBSERVATION</subject></subj-group></article-categories><title-group><article-title>Сакроилиит при подагре</article-title><trans-title-group xml:lang="en"><trans-title>Sacroiliitis in gout: Difficulties of diagnosis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2246-686X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Агафонова</surname><given-names>Е. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Agafonova</surname><given-names>E. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Агафонова Екатерина Михайловна.</p><p>115522, Москва, Каширское шоссе, 34а</p></bio><bio xml:lang="en"><p>Ekaterina M. Agafonova.</p><p>115522, Moscow, Kashirskoye Highway, 34A</p></bio><email xlink:type="simple">busy89@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4626-0938</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аристова</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Aristova</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34а</p></bio><bio xml:lang="en"><p>Maria V. Aristova.</p><p>115522, Moscow, Kashirskoye Highway, 34A</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1191-5831</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Елисеев</surname><given-names>М. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Eliseev</surname><given-names>M. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34а</p></bio><bio xml:lang="en"><p>Maxim S. Eliseev.</p><p>115522, Moscow, Kashirskoye Highway, 34A</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5394-7869</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Желябина</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zheliabina</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34а</p></bio><bio xml:lang="en"><p>Olga V. Zheliabina.</p><p>115522, Moscow, Kashirskoye Highway, 34A</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3195-5187</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Эрдес</surname><given-names>Ш.</given-names></name><name name-style="western" xml:lang="en"><surname>Erdes</surname><given-names>Sh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34а</p></bio><bio xml:lang="en"><p>Shandor Erdes.</p><p>115522, Moscow, Kashirskoye Highway, 34A</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7418-9369</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Смирнов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Smirnov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34а</p></bio><bio xml:lang="en"><p>Alexander V. Smirnov.</p><p>115522, Moscow, Kashirskoye Highway, 34A</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.A. Nasonova Research Institute of Rheumatology</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>01</day><month>01</month><year>2024</year></pub-date><volume>61</volume><issue>6</issue><fpage>763</fpage><lpage>768</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Агафонова Е.М., Аристова М.В., Елисеев М.С., Желябина О.В., Эрдес Ш., Смирнов А.В., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Агафонова Е.М., Аристова М.В., Елисеев М.С., Желябина О.В., Эрдес Ш., Смирнов А.В.</copyright-holder><copyright-holder xml:lang="en">Agafonova E.M., Aristova M.V., Eliseev M.S., Zheliabina O.V., Erdes S., Smirnov A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://rsp.mediar-press.net/rsp/article/view/3476">https://rsp.mediar-press.net/rsp/article/view/3476</self-uri><abstract><p>Подагра – наиболее распространенное хроническое аутовоспалительное заболевание. Ее развитие связано со стойкой гиперурикемией, которая обусловлена как внешнесредовыми, так и генетическими факторами и приводит к отложению кристаллов моноурата натрия в различных тканях и органах. Подагра чаще встречается у мужчин, чем у женщин детородного возраста, что объясняется урикозурическим действием эстрогена, однако после менопаузы частота развития подагры у женщин значительно возрастает. В дебюте заболевания наиболее часто в патологический процесс вовлекаются первый плюснефаланговый сустав, голеностопные и коленные суставы. Однако в литературе имеются единичные сообщения о редком поражении подагрой осевого скелета, например, крестцово-подвздошного сустава, при котором характер боли и изменения, выявляемые при магнитно-резонансной томографии и рентгенологическом исследовании, могут имитировать спондилоартрит. В статье представлен редкий случай поражения осевого скелета у пациентки 57 лет с подагрой, проявившейся острой воспалительной болью в спине и артритом суставов нижних конечностей.</p></abstract><trans-abstract xml:lang="en"><p>Gout is the most common chronic autoinflammatory disease, the development of which is associated with persistent hyperuricemia caused by both environmental and genetic factors, which leads to the deposition of sodium monourate crystals in various tissues and organs of the human body. Gout is more common in men than in women of childbearing age, due to the uricosuric effect of estrogen, however, after menopause, the incidence of gout in women increases significantly. At the onset of the disease, the first metatarsophalangeal joint, ankle and knee joints are most often involved in the pathological process. However, there are isolated reports in the literature about a rare gout lesion of the axial skeleton, for example, the sacroiliac joint, in which the nature of the pain syndrome, magnetic resonance imaging, and X-ray picture can mimic spondyloarthritis. The article presents a rare case of damage to the axial skeleton in a 57-year-old patient with gout, manifested by acute inflammatory back pain and arthritis of the lower extremities.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>подагра</kwd><kwd>аксиальный спондилоартрит</kwd><kwd>сакроилиит</kwd></kwd-group><kwd-group xml:lang="en"><kwd>gout</kwd><kwd>axial spondyloarthritis</kwd><kwd>sacroiliitis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Robinson PC. Gout – An update of aetiology, genetics, co-morbidities and management. Maturitas. 2018;118:67-73. doi: 10.1016/j.maturitas.2018.10.012</mixed-citation><mixed-citation xml:lang="en">Robinson PC. Gout – An update of aetiology, genetics, co-morbidities and management. Maturitas. 2018;118:67-73. doi: 10.1016/j.maturitas.2018.10.012</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Елисеев МС. Поражение позвоночника при подагре. РМЖ. Ревматология. 2016;24(2):85-89.</mixed-citation><mixed-citation xml:lang="en">Eliseev MS. Gouty lesions in the spine. RMJ. Rheumatology. 2016;24(2):85-99 (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Konatalapalli RM, Demarco PJ, Jelinek JS, Murphey M, Gibson M, Jennings B, et al. Gout in the axial skeleton. J Rheumatol. 2009;36(3):609-613. doi: 10.3899/jrheum.080374</mixed-citation><mixed-citation xml:lang="en">Konatalapalli RM, Demarco PJ, Jelinek JS, Murphey M, Gibson M, Jennings B, et al. Gout in the axial skeleton. J Rheumatol. 2009;36(3):609-613. doi: 10.3899/jrheum.080374</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">de Mello FM, Helito PV, Bordalo-Rodrigues M, Fuller R, Halpern AS. Axial gout is frequently associated with the presence of current tophi, although not with spinal symptoms. Spine (Phila Pa 1976). 2014;39(25):1531-1536. doi: 10.1097/BRS.0000000000000633</mixed-citation><mixed-citation xml:lang="en">de Mello FM, Helito PV, Bordalo-Rodrigues M, Fuller R, Halpern AS. Axial gout is frequently associated with the presence of current tophi, although not with spinal symptoms. Spine (Phila Pa 1976). 2014;39(25):1531-1536. doi: 10.1097/BRS.0000000000000633</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">King JC, Nicholas C. Gouty arthropathy of the lumbar spine: A case report and review of the literature. Spine (Phila Pa 1976). 1997;22(19):2309-2312. doi: 10.1097/00007632-199710010-00023</mixed-citation><mixed-citation xml:lang="en">King JC, Nicholas C. Gouty arthropathy of the lumbar spine: A case report and review of the literature. Spine (Phila Pa 1976). 1997;22(19):2309-2312. doi: 10.1097/00007632-199710010-00023</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Сороцкая ВН, Елисеев МС. Подагра с тофусом, имитирующим опухоль грудного отдела позвоночника. Научно-практическая ревматология. 2018;56(1):113-116. doi: 10.14412/1995-4484-2018-113-116</mixed-citation><mixed-citation xml:lang="en">Sorotskaya VN, Eliseev MS. Gout with tophus mimicking a tumor of the thoracic spine. Nauchno-Prakticheskaya Revmatologia = Rheumatology Science and Practice. 2018;56(1):113-116 (In Russ.). doi: 10.14412/1995-4484-2018-113-116</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Alarcón-Segovia DA, Cetina JA, Díaz-Jouanen E. Sarcroilaic joints in primary gout. Clinical and roentgenographic study of 143 patients. Am J Roentgenol Radium Ther Nucl Med. 1973;118(2):438-443. doi: 10.2214/ajr.118.2.438</mixed-citation><mixed-citation xml:lang="en">Alarcón-Segovia DA, Cetina JA, Díaz-Jouanen E. Sarcroilaic joints in primary gout. Clinical and roentgenographic study of 143 patients. Am J Roentgenol Radium Ther Nucl Med. 1973;118(2):438-443. doi: 10.2214/ajr.118.2.438</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Cardoso FN, Omoumi P, Wieers G, Maldague B, Malghem J, Lecouvet FE, et al. Spinal and sacroiliac gouty arthritis: Report of a case and review of the literature. Acta Radiol Short Rep. 2014;3(8):2047981614549269. doi: 10.1177/2047981614549269</mixed-citation><mixed-citation xml:lang="en">Cardoso FN, Omoumi P, Wieers G, Maldague B, Malghem J, Lecouvet FE, et al. Spinal and sacroiliac gouty arthritis: Report of a case and review of the literature. Acta Radiol Short Rep. 2014;3(8):2047981614549269. doi: 10.1177/2047981614549269</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Monu JU, Pope TL Jr. Gout: A clinical and radiologic review. Radiol Clin North Am. 2004;42(1):169-184. doi: 10.1016/S0033-8389(03)00158-1</mixed-citation><mixed-citation xml:lang="en">Monu JU, Pope TL Jr. Gout: A clinical and radiologic review. Radiol Clin North Am. 2004;42(1):169-184. doi: 10.1016/S0033-8389(03)00158-1</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Jajić I. Gout in the spine and sacro-iliac joints: radiological manifestations. Skeletal Radiol. 1982;8(3):209-212. doi: 10.1007/BF00355508</mixed-citation><mixed-citation xml:lang="en">Jajić I. Gout in the spine and sacro-iliac joints: radiological manifestations. Skeletal Radiol. 1982;8(3):209-212. doi: 10.1007/BF00355508</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Perez-Ruiz F, Castillo E, Chinchilla SP, Herrero-Beites AM. Clinical manifestations and diagnosis of gout. Rheum Dis Clin North Am. 2014;40(2):193-206. doi: 10.1016/j.rdc.2014.01.003</mixed-citation><mixed-citation xml:lang="en">Perez-Ruiz F, Castillo E, Chinchilla SP, Herrero-Beites AM. Clinical manifestations and diagnosis of gout. Rheum Dis Clin North Am. 2014;40(2):193-206. doi: 10.1016/j.rdc.2014.01.003</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Wernick R, Winkler C, Campbell S. Tophi as the initial manifestation of gout. Report of six cases and review of the literature. Arch Intern Med. 1992;152(4):873-876.</mixed-citation><mixed-citation xml:lang="en">Wernick R, Winkler C, Campbell S. Tophi as the initial manifestation of gout. Report of six cases and review of the literature. Arch Intern Med. 1992;152(4):873-876.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Namas R, Hegazin SB, Memişoğlu E, Abhay J. Lower back pain as a manifestation of acute gouty sacroiliitis: Utilization of dual-energy computed tomography (DECT) in establishing a diagnosis. Eur J Rheumatol 2019;6(4):216-218. doi: 10.5152/eurjrheum.2019.18097</mixed-citation><mixed-citation xml:lang="en">Namas R, Hegazin SB, Memişoğlu E, Abhay J. Lower back pain as a manifestation of acute gouty sacroiliitis: Utilization of dual-energy computed tomography (DECT) in establishing a diagnosis. Eur J Rheumatol 2019;6(4):216-218. doi: 10.5152/eurjrheum.2019.18097</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Cardoso FN, Omoumi P, Wieers G, Maldague B, Malghem J, Lecouvet FE, et al. Spinal and sacroiliac gouty arthritis: Report of a case and review of the literature. Acta Radiol Short Rep. 2014;3(8):2047981614549269. doi: 10.1177/2047981614549269</mixed-citation><mixed-citation xml:lang="en">Cardoso FN, Omoumi P, Wieers G, Maldague B, Malghem J, Lecouvet FE, et al. Spinal and sacroiliac gouty arthritis: Report of a case and review of the literature. Acta Radiol Short Rep. 2014;3(8):2047981614549269. doi: 10.1177/2047981614549269</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Konatalapalli RM, Lumezanu E, Jelinek JS, Murphey MD, Wang H, Weinstein A. Correlates of axial gout: A cross-sectional study. J Rheumatol. 2012;39(7):1445-1449. doi: 10.3899/jrheum.111517</mixed-citation><mixed-citation xml:lang="en">Konatalapalli RM, Lumezanu E, Jelinek JS, Murphey MD, Wang H, Weinstein A. Correlates of axial gout: A cross-sectional study. J Rheumatol. 2012;39(7):1445-1449. doi: 10.3899/jrheum.111517</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Glazebrook KN, Guimarães LS, Murthy NS, Black DF, Bongartz T, Manek NJ, et al. Identification of intraarticular and periarticular uric acid crystals with dual-energy CT: Initial evaluation. Radiology. 2011;261(2):516-524. doi: 10.1148/radiol.11102485</mixed-citation><mixed-citation xml:lang="en">Glazebrook KN, Guimarães LS, Murthy NS, Black DF, Bongartz T, Manek NJ, et al. Identification of intraarticular and periarticular uric acid crystals with dual-energy CT: Initial evaluation. Radiology. 2011;261(2):516-524. doi: 10.1148/radiol.11102485</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">King JC, Nicholas C. Gouty arthropathy of the lumbar spine: A case report and review of the literature. Spine (Phila Pa 1976). 1997;22(19):2309-2312. doi: 10.1097/00007632-199710010-00023</mixed-citation><mixed-citation xml:lang="en">King JC, Nicholas C. Gouty arthropathy of the lumbar spine: A case report and review of the literature. Spine (Phila Pa 1976). 1997;22(19):2309-2312. doi: 10.1097/00007632-199710010-00023</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Dhôte R, Roux FX, Bachmeyer C, Tudoret L, Daumas-Duport C, Christoforov B. Extradural spinal tophaceous gout: Evolution with medical treatment. Clin Exp Rheumatol. 1997; 15(4):421-423.</mixed-citation><mixed-citation xml:lang="en">Dhôte R, Roux FX, Bachmeyer C, Tudoret L, Daumas-Duport C, Christoforov B. Extradural spinal tophaceous gout: Evolution with medical treatment. Clin Exp Rheumatol. 1997; 15(4):421-423.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Beier CP, Hartmann A, Woertgen C, Brawanski A, Rothoerl RD. A large, erosive intraspinal and paravertebral gout tophus. Case report. J Neurosurg Spine. 2005;3(6):485-487. doi: 10.3171/spi.2005.3.6.0485</mixed-citation><mixed-citation xml:lang="en">Beier CP, Hartmann A, Woertgen C, Brawanski A, Rothoerl RD. A large, erosive intraspinal and paravertebral gout tophus. Case report. J Neurosurg Spine. 2005;3(6):485-487. doi: 10.3171/spi.2005.3.6.0485</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Draganescu M, Leventhal LJ. Spinal gout: Case report and review of the literature. J Clin Rheumatol. 2004;10(2):74-79. doi: 10.1097/01.rhu.0000120898.82192.f4</mixed-citation><mixed-citation xml:lang="en">Draganescu M, Leventhal LJ. Spinal gout: Case report and review of the literature. J Clin Rheumatol. 2004;10(2):74-79. doi: 10.1097/01.rhu.0000120898.82192.f4</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
