rspНаучно-практическая ревматологияRheumatology Science and Practice1995-44841995-4492IMA-PRESS, LLC10.47360/1995-4484-2023-689-699rsp-3481Research ArticleФОРУМ МОЛОДЫХ УЧЕНЫХYOUNG SCIENTISTS FORUMВозможности магнитно-резонансной томографии в диагностике идиопатических воспалительных миопатийCapabilities of magnetic resonance imaging in the diagnosis of idiopathic inflammatory myopathieshttps://orcid.org/0000-0002-4530-8717КоломейчукА. А.KolomeychukA. A.

Коломейчук Алёна Алексеевна – аспирант 2-го года ФГБНУ НИИР им. В.А. Насоновой.

115522, Москва, Каширское шоссе, 34а

Научный руководитель: д.м.н., профессор Ананьева Лидия Петровна.

Alena A. Kolomeychuk.

115522, Moscow, Kashirskoye Highway, 34A

alenakolomei@gmail.comФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»РоссияV.A. Nasonova Research Institute of RheumatologyRussian Federation202301012024616689699Copyright © Коломейчук А.А., 20242024Коломейчук А.А.Kolomeychuk A.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://rsp.mediar-press.net/rsp/article/view/3481

Идиопатические воспалительные миопатии (ИВМ) – группа хронических аутоиммунных заболеваний, характеризующихся наличием проксимальной мышечной слабости и большим спектром внемышечных проявлений. Представителями ИВМ являются дерматомиозит; полимиозит; антисинтетазный синдром; иммунозависимая некротизирующая миопатия; спорадический миозит с включениями; миозит, ассоциированный с другими ревматическими заболеваниями; миозит, ассоциированный с паранеопластическим процессом. Учитывая низкую частоту, гетерогенность клинических проявлений, трудности в определении и трактовке миозит-специфических и миозит-ассоциированных аутоантител, продолжается поиск объективных методов визуализации поражения мышц как для верификации диагноза и определения фенотипа данного заболевания, так и для динамического наблюдения. Одним из наиболее перспективных методов является магнитно-резонансная томография (МРТ) мышц. В обзоре освещены возможности МРТ для оценки мышечных повреждений, в частности, наиболее характерные МРТ-признаки ИВМ и их особенности при разных фенотипах заболевания; представлены клинические примеры.

Idiopathic inflammatory myopathies (IIM) are a group of chronic autoimmune conditions characterized by proximal muscle weakness and potentially accompanied by a range of extramuscular clinical manifestations. There are subtypes of IIM including dermatomyositis (DM), polymyositis (PM), immune-mediated necrotizing myopathy (IMNM), sporadic inclusion body myositis (sIBM), overlap myositis (OM) with subgroup of anti-synthetase syndrome (ASS) and cancer-associated myositis. Taking into account rarity of the disease, heterogeneity of clinical presentation, difficulties in detection methods and interpretation of myositis associated autoantibodies (MAAs) and myositis specific autoantibodies (MSAs), search for objective imaging methods of muscle damage continues. This is important to definitive diagnosis, predicting subtypes of IIM and case follow-up. One of the most promising methods is magnetic resonance imaging (MRI). The aim of the review was to examine the role of MRI in assessment muscle damage, in particular, most typical MRI-findings and there features in different types of IIM with further clinical cases.

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The authors declare that there are no conflicts of interest present.