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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rsp</journal-id><journal-title-group><journal-title xml:lang="ru">Научно-практическая ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Rheumatology Science and Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-4484</issn><issn pub-type="epub">1995-4492</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.47360/1995-4484-2024-377-384</article-id><article-id custom-type="elpub" pub-id-type="custom">rsp-3603</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS AND LECTURES</subject></subj-group></article-categories><title-group><article-title>Волчаночный нефрит: современные представления о терапии. (Часть II)</article-title><trans-title-group xml:lang="en"><trans-title>Lupus nephritis. Part II, modern ideas about therapy</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1663-7810</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Асеева</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Aseeva</surname><given-names>Elena A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Асеева Елена Александровна</p><p>115522, Москва, Каширское шоссе, 34а</p></bio><bio xml:lang="en"><p>115522, Moscow, Kashirskoye Highway, 34A</p></bio><email xlink:type="simple">eaasseeva@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5206-1732</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Соловьев</surname><given-names>С. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Solovyev</surname><given-names>Sergey K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34а</p></bio><bio xml:lang="en"><p>115522, Moscow, Kashirskoye Highway, 34A</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4275-0315</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Козловская</surname><given-names>Н. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Kozlovskaya</surname><given-names>Natalia L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>117198, Москва, ул. Миклухо-Маклая</p></bio><bio xml:lang="en"><p>117198, Moscow, Miklukho-Maklaya str., 6 </p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7847-1679</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Баранов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Baranov</surname><given-names>Andrey A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>150000, Ярославль, ул. Революционная, 5</p></bio><bio xml:lang="en"><p>150000, Yaroslavl, Revolyutsionnaya str., 5 </p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1598-8360</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Насонов</surname><given-names>Е. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Nasonov</surname><given-names>Evgeny L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34а</p><p>119991, Москва, ул. Трубецкая, 8, стр. 2 </p></bio><bio xml:lang="en"><p>115522, Moscow, Kashirskoye Highway, 34A</p><p>119991, Moscow, Trubetskaya str., 8, building 2</p></bio><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.A. Nasonova Research Institute of Rheumatology</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГАОУ ВО «Российский университет дружбы народов имени Патриса Лумумбы»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Peoples’ Friendship University of Russia named after Patrice &#13;
Lumumba</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБОУ ВО «Ярославский государственный медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Yaroslavl State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»; ФГАОУ ВО «Первый Московский государственный медицинский университет имени И.М. Сеченова» Минздрава России (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.A. Nasonova Research Institute of Rheumatology; I.M. Sechenov First Moscow State Medical University of the Ministry of Health Care of the Russian Federation (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>02</day><month>09</month><year>2024</year></pub-date><volume>62</volume><issue>4</issue><fpage>377</fpage><lpage>384</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Асеева Е.А., Соловьев С.К., Козловская Н.Л., Баранов А.А., Насонов Е.Л., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Асеева Е.А., Соловьев С.К., Козловская Н.Л., Баранов А.А., Насонов Е.Л.</copyright-holder><copyright-holder xml:lang="en">Aseeva E.A., Solovyev S.K., Kozlovskaya N.L., Baranov A.A., Nasonov E.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://rsp.mediar-press.net/rsp/article/view/3603">https://rsp.mediar-press.net/rsp/article/view/3603</self-uri><abstract><p>Во второй части обзора представлены современные данные о стратегии терапии волчаночного нефрита с учетом морфологического класса поражения почек, особенностей течения и активности. Описаны подходы к мониторингу и оценке эффективности лечения, проблемы достижения полного и частичного почечного ответа. Дана характеристика классических и инновационных методов терапии.</p></abstract><trans-abstract xml:lang="en"><p>The second part of the review presents current data on the treatment strategy for lupus nephritis, considering the morphological class of kidney damage, course and activity. Approaches to monitoring and evaluating the effectiveness of treatment, the problems of achieving a complete and partial renal response are described. The characteristic of classical and innovative methods of therapy is given.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>системная красная волчанка</kwd><kwd>волчаночный нефрит</kwd><kwd>лечение</kwd></kwd-group><kwd-group xml:lang="en"><kwd>systemic lupus erythematosus</kwd><kwd>lupus nephritis</kwd><kwd>treatment</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Статья подготовлена по фундаментальной научной теме FURS-2022-003 № 122040400024-07.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ward MM. Hospital experience and mortality in patients with systemic lupus erythematosus: Which patients benefit most from treatment at highly experienced hospitals? J Rheumatol. 2002;29(6):1198-1206.</mixed-citation><mixed-citation xml:lang="en">Ward MM. Hospital experience and mortality in patients with systemic lupus erythematosus: Which patients benefit most from treatment at highly experienced hospitals? J Rheumatol. 2002;29(6):1198-1206.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Bertsias GK, Tektonidou M, Amoura Z, Aringer M, Bajema I, Berden JH, et al.; European League Against Rheumatism and European Renal Association-European Dialysis and Transplant Association. Joint European League Against Rheumatism and European Renal Association-European Dialysis and Transplant Association (EULAR/ERA-EDTA) recommendations for the management of adult and paediatric lupus nephritis. Ann Rheum Dis. 2012;71(11):1771-1782. doi: 10.1136/annrheumdis-2012-201940</mixed-citation><mixed-citation xml:lang="en">Bertsias GK, Tektonidou M, Amoura Z, Aringer M, Bajema I, Berden JH, et al.; European League Against Rheumatism and European Renal Association-European Dialysis and Transplant Association. Joint European League Against Rheumatism and European Renal Association-European Dialysis and Transplant Association (EULAR/ERA-EDTA) recommendations for the management of adult and paediatric lupus nephritis. Ann Rheum Dis. 2012;71(11):1771-1782. doi: 10.1136/annrheumdis-2012-201940</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Houssiau FA, Vasconcelos C, D’Cruz D, Sebastiani GD, de Ra mon Garrido E, Danieli MG, et al. Early response to immunosuppressive therapy predicts good renal outcome in lupus nephritis: Lessons from long-term followup of patients in the Euro-Lupus Nephritis Trial. Arthritis Rheum. 2004;50(12):3934-3940. doi: 10.1002/art.20666</mixed-citation><mixed-citation xml:lang="en">Houssiau FA, Vasconcelos C, D’Cruz D, Sebastiani GD, de Ra mon Garrido E, Danieli MG, et al. Early response to immunosuppressive therapy predicts good renal outcome in lupus nephritis: Lessons from long-term followup of patients in the Euro-Lupus Nephritis Trial. Arthritis Rheum. 2004;50(12):3934-3940. doi: 10.1002/art.20666</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Chen YE, Korbet SM, Katz RS, Schwartz MM, Lewis EJ; Collaborative Study Group. Value of a complete or partial remission in severe lupus nephritis. Clin J Am Soc Nephrol. 2008;3(1):46-53. doi: 10.2215/CJN.03280807</mixed-citation><mixed-citation xml:lang="en">Chen YE, Korbet SM, Katz RS, Schwartz MM, Lewis EJ; Collaborative Study Group. Value of a complete or partial remission in severe lupus nephritis. Clin J Am Soc Nephrol. 2008;3(1):46-53. doi: 10.2215/CJN.03280807</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Illei GG, Takada K, Parkin D, Austin HA, Crane M, Yarboro CH, et al. Renal flares are common in patients with severe proliferative lupus nephritis treated with pulse immunosuppressive therapy: Long-term followup of a cohort of 145 patients participating in randomized controlled studies. Arthritis Rheum. 2002;46(4):995-1002. doi: 10.1002/art.10142</mixed-citation><mixed-citation xml:lang="en">Illei GG, Takada K, Parkin D, Austin HA, Crane M, Yarboro CH, et al. Renal flares are common in patients with severe proliferative lupus nephritis treated with pulse immunosuppressive therapy: Long-term followup of a cohort of 145 patients participating in randomized controlled studies. Arthritis Rheum. 2002;46(4):995-1002. doi: 10.1002/art.10142</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Moroni G, Quaglini S, Gallelli B, Banfi G, Messa P, Ponticelli C. The long-term outcome of 93 patients with proliferative lupus nephritis. Nephrol Dial Transplant. 2007;22(9):2531-2539. doi: 10.1093/ndt/gfm245</mixed-citation><mixed-citation xml:lang="en">Moroni G, Quaglini S, Gallelli B, Banfi G, Messa P, Ponticelli C. The long-term outcome of 93 patients with proliferative lupus nephritis. Nephrol Dial Transplant. 2007;22(9):2531-2539. doi: 10.1093/ndt/gfm245</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Kostopoulou M, Fanouriakis A, Cheema K, Boletis J, Bertsias G, Jayne D, et al. Management of lupus nephritis: A systematic literature review informing the 2019 update of the joint EULAR and European Renal Association-European Dialysis and Transplant Association (EULAR/ERA-EDTA) recommendations. RMD Open. 2020;6(2):e001263. doi: 10.1136/rmdopen-2020-001263</mixed-citation><mixed-citation xml:lang="en">Kostopoulou M, Fanouriakis A, Cheema K, Boletis J, Bertsias G, Jayne D, et al. Management of lupus nephritis: A systematic literature review informing the 2019 update of the joint EULAR and European Renal Association-European Dialysis and Transplant Association (EULAR/ERA-EDTA) recommendations. RMD Open. 2020;6(2):e001263. doi: 10.1136/rmdopen-2020-001263</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Londoño Jimenez A, Mowrey WB, Putterman C, Buyon J, Goilav B, Broder A. Brief report: Tubulointerstitial damage in lupus nephritis: A comparison of the factors associated with tubulointerstitial inflammation and renal scarring. Arthritis Rheumatol. 2018;70(11):1801-1806. doi: 10.1002/art.40575</mixed-citation><mixed-citation xml:lang="en">Londoño Jimenez A, Mowrey WB, Putterman C, Buyon J, Goilav B, Broder A. Brief report: Tubulointerstitial damage in lupus nephritis: A comparison of the factors associated with tubulointerstitial inflammation and renal scarring. Arthritis Rheumatol. 2018;70(11):1801-1806. doi: 10.1002/art.40575</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Galindo-Izquierdo M, Rodriguez-Almaraz E, Pego-Reigosa JM, López-Longo FJ, Calvo-Alén J, Olivé A, et al.; RELESSER Group, from the Spanish Society of Rheumatology Systemic Autoimmune Diseases Study Group (EASSER). Characterization of patients with lupus nephritis included in a large cohort from the Spanish Society of Rheumatology Registry of Patients with Systemic Lupus Erythematosus (RELESSER). Medicine (Baltimore). 2016;95(9):e2891. doi: 10.1097/MD.0000000000002891</mixed-citation><mixed-citation xml:lang="en">Galindo-Izquierdo M, Rodriguez-Almaraz E, Pego-Reigosa JM, López-Longo FJ, Calvo-Alén J, Olivé A, et al.; RELESSER Group, from the Spanish Society of Rheumatology Systemic Autoimmune Diseases Study Group (EASSER). Characterization of patients with lupus nephritis included in a large cohort from the Spanish Society of Rheumatology Registry of Patients with Systemic Lupus Erythematosus (RELESSER). Medicine (Baltimore). 2016;95(9):e2891. doi: 10.1097/MD.0000000000002891</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Pokroy-Shapira E, Gelernter I, Molad Y. Evolution of chronic kidney disease in patients with systemic lupus erythematosus over a long-period follow-up: A single-center inception cohort study. Clin Rheumatol. 2014;33(5):649-657. doi: 10.1007/s10067-014-2527-0</mixed-citation><mixed-citation xml:lang="en">Pokroy-Shapira E, Gelernter I, Molad Y. Evolution of chronic kidney disease in patients with systemic lupus erythematosus over a long-period follow-up: A single-center inception cohort study. Clin Rheumatol. 2014;33(5):649-657. doi: 10.1007/s10067-014-2527-0</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Ассоциация нефрологов, Научное общество нефрологов России, Общероссийская общественная организация нефрологов «Российское диализное общество». Клинические рекомендации. Диагностика и лечение волчаночного нефрита. М.;2021. [Association of Nephrologists, Scientific Society of Nephrologists of Russia, All-Russian Public Organization of Nephrologists “Russian Dialysis Society”. Clinical guidelines. Diagnosis and treatment of lupus nephritis. Moscow;2021. (In Russ.)]. URL: http://nonr.su/wp-content/uploads/2021/09/Диагностика-и-лечение-волчаночного-нефрита-проект.pdf (Accessed: DD Month 2020).</mixed-citation><mixed-citation xml:lang="en">Ассоциация нефрологов, Научное общество нефрологов России, Общероссийская общественная организация нефрологов «Российское диализное общество». Клинические рекомендации. Диагностика и лечение волчаночного нефрита. М.;2021. [Association of Nephrologists, Scientific Society of Nephrologists of Russia, All-Russian Public Organization of Nephrologists “Russian Dialysis Society”. Clinical guidelines. Diagnosis and treatment of lupus nephritis. Moscow;2021. (In Russ.)]. URL: http://nonr.su/wp-content/uploads/2021/09/Диагностика-и-лечение-волчаночного-нефрита-проект.pdf (Accessed: DD Month 2020).</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Fanouriakis A, Kostopoulou M, Cheema K, Anders HJ, Aringer M, Bajema I, et al. 2019 update of the Joint European League Against Rheumatism and European Renal Association-European Dialysis and Transplant Association (EULAR/ERA-EDTA) recommendations for the management of lupus nephritis. Ann Rheum Dis. 2020;79(6):713-723. doi: 10.1136/annrheumdis-2020-216924</mixed-citation><mixed-citation xml:lang="en">Fanouriakis A, Kostopoulou M, Cheema K, Anders HJ, Aringer M, Bajema I, et al. 2019 update of the Joint European League Against Rheumatism and European Renal Association-European Dialysis and Transplant Association (EULAR/ERA-EDTA) recommendations for the management of lupus nephritis. Ann Rheum Dis. 2020;79(6):713-723. doi: 10.1136/annrheumdis-2020-216924</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Gourley MF, Austin HA 3rd, Scott D, Yarboro CH, Vaughan EM, Muir J, et al. Methylprednisolone and cyclophosphamide, alone or in combination, in patients with lupus nephritis. A randomized, controlled trial. Ann Intern Med. 1996;125(7):549-557. doi: 10.7326/0003-4819-125-7-199610010-00003</mixed-citation><mixed-citation xml:lang="en">Gourley MF, Austin HA 3rd, Scott D, Yarboro CH, Vaughan EM, Muir J, et al. Methylprednisolone and cyclophosphamide, alone or in combination, in patients with lupus nephritis. A randomized, controlled trial. Ann Intern Med. 1996;125(7):549-557. doi: 10.7326/0003-4819-125-7-199610010-00003</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Brugos B, Sebestyen L, Tarr T, Vincze Z. Use of cyclophosphamide and other immunosuppressive drugs in the treatment of patients with lupus nephritis. Pharmazie. 2014;69(6):442-444.</mixed-citation><mixed-citation xml:lang="en">Brugos B, Sebestyen L, Tarr T, Vincze Z. Use of cyclophosphamide and other immunosuppressive drugs in the treatment of patients with lupus nephritis. Pharmazie. 2014;69(6):442-444.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Mitjavila F, Pac V, Moga I, Poveda R, Vidaller A, Carrera M, et al. Clinicopathological correlations and prognostic factors in lupus nephritis. Clin Exp Rheumatol. 1997;15(6):625-631.</mixed-citation><mixed-citation xml:lang="en">Mitjavila F, Pac V, Moga I, Poveda R, Vidaller A, Carrera M, et al. Clinicopathological correlations and prognostic factors in lupus nephritis. Clin Exp Rheumatol. 1997;15(6):625-631.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Fanouriakis A, Tziolos N, Bertsias G, Boumpas DT. Update οn the diagnosis and management of systemic lupus erythematosus. Ann Rheum Dis. 2021;80(1):14-25. doi: 10.1136/annrheumdis-2020-218272</mixed-citation><mixed-citation xml:lang="en">Fanouriakis A, Tziolos N, Bertsias G, Boumpas DT. Update οn the diagnosis and management of systemic lupus erythematosus. Ann Rheum Dis. 2021;80(1):14-25. doi: 10.1136/annrheumdis-2020-218272</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Moroni G, Gatto M, Tamborini F, Quaglini S, Radice F, Saccon F, et al. Lack of EULAR/ERA-EDTA response at 1 year predicts poor long-term renal outcome in patients with lupus nephritis. Ann Rheum Dis. 2020;79(8):1077-1083. doi: 10.1136/annrheumdis-2020-216965</mixed-citation><mixed-citation xml:lang="en">Moroni G, Gatto M, Tamborini F, Quaglini S, Radice F, Saccon F, et al. Lack of EULAR/ERA-EDTA response at 1 year predicts poor long-term renal outcome in patients with lupus nephritis. Ann Rheum Dis. 2020;79(8):1077-1083. doi: 10.1136/annrheumdis-2020-216965</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Dooley MA, Jayne D, Ginzler EM, Isenberg D, Olsen NJ, Wofsy D, et al.; ALMS Group. Mycophenolate versus azathioprine as maintenance therapy for lupus nephritis. N Engl J Med. 2011;365(20):1886-1895. doi: 10.1056/NEJMoa1014460</mixed-citation><mixed-citation xml:lang="en">Dooley MA, Jayne D, Ginzler EM, Isenberg D, Olsen NJ, Wofsy D, et al.; ALMS Group. Mycophenolate versus azathioprine as maintenance therapy for lupus nephritis. N Engl J Med. 2011;365(20):1886-1895. doi: 10.1056/NEJMoa1014460</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Hanly JG, O’Keeffe AG, Su L, Urowitz MB, Romero-Diaz J, Gordon C, et al. The frequency and outcome of lupus nephritis: Results from an international inception cohort study. Rheumatology (Oxford). 2016;55(2):252-262. doi: 10.1093/rheumatology/kev311</mixed-citation><mixed-citation xml:lang="en">Hanly JG, O’Keeffe AG, Su L, Urowitz MB, Romero-Diaz J, Gordon C, et al. The frequency and outcome of lupus nephritis: Results from an international inception cohort study. Rheumatology (Oxford). 2016;55(2):252-262. doi: 10.1093/rheumatology/kev311</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Moroni G, Gatto M, Raffiotta F, Binda V, Frangou E, Lightstone L, et al. Can we withdraw immunosuppressants in patients with lupus nephritis in remission? An expert debate. Autoimmun Rev. 2018;17(1):11-18. doi: 10.1016/j.autrev.2017.11.003</mixed-citation><mixed-citation xml:lang="en">Moroni G, Gatto M, Raffiotta F, Binda V, Frangou E, Lightstone L, et al. Can we withdraw immunosuppressants in patients with lupus nephritis in remission? An expert debate. Autoimmun Rev. 2018;17(1):11-18. doi: 10.1016/j.autrev.2017.11.003</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Grootscholten C, Berden JHM. Discontinuation of immunosuppression in proliferative lupus nephritis: Is it possible? Nephrol Dial Transplant. 2006;21:1465-1469. doi: 10.1093/ndt/gfl208</mixed-citation><mixed-citation xml:lang="en">Grootscholten C, Berden JHM. Discontinuation of immunosuppression in proliferative lupus nephritis: Is it possible? Nephrol Dial Transplant. 2006;21:1465-1469. doi: 10.1093/ndt/gfl208</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">van Vollenhoven RF, Mosca M, Bertsias G, Isenberg D, Kuhn A, Lerstrøm K, et al. Treat-to-target in systemic lupus erythematosus: Recommendations from an international task force. Ann Rheum Dis. 2014;73(6):958-967. doi: 10.1136/annrheumdis-2013-205139</mixed-citation><mixed-citation xml:lang="en">van Vollenhoven RF, Mosca M, Bertsias G, Isenberg D, Kuhn A, Lerstrøm K, et al. Treat-to-target in systemic lupus erythematosus: Recommendations from an international task force. Ann Rheum Dis. 2014;73(6):958-967. doi: 10.1136/annrheumdis-2013-205139</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Arnaud L, Tektonidou MG. Long-term outcomes in systemic lupus erythematosus: Trends over time and major contributors. Rheumatology. 2020;59:29-38. doi: 10.1093/rheumatology/keaa382</mixed-citation><mixed-citation xml:lang="en">Arnaud L, Tektonidou MG. Long-term outcomes in systemic lupus erythematosus: Trends over time and major contributors. Rheumatology. 2020;59:29-38. doi: 10.1093/rheumatology/keaa382</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Laskari K, Tzioufas AG, Antoniou A, Moutsopoulos HM. Longterm followup after tapering mycophenolate mofetil during maintenance treatment for proliferative lupus nephritis. J Rheumatol. 2011;38:1304-1308. doi: 10.3899/jrheum.101249</mixed-citation><mixed-citation xml:lang="en">Laskari K, Tzioufas AG, Antoniou A, Moutsopoulos HM. Longterm followup after tapering mycophenolate mofetil during maintenance treatment for proliferative lupus nephritis. J Rheumatol. 2011;38:1304-1308. doi: 10.3899/jrheum.101249</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Kostopoulou M, Mukhtyar CB, Bertsias G, Boumpas DT, Fanouriakis A. Management of systemic lupus erythematosus: A systematic literature review informing the 2023 update of the EULAR recommendations. Ann Rheum Dis. 2024 May 22:ard-2023-225319. doi: 10.1136/ard-2023-225319</mixed-citation><mixed-citation xml:lang="en">Kostopoulou M, Mukhtyar CB, Bertsias G, Boumpas DT, Fanouriakis A. Management of systemic lupus erythematosus: A systematic literature review informing the 2023 update of the EULAR recommendations. Ann Rheum Dis. 2024 May 22:ard-2023-225319. doi: 10.1136/ard-2023-225319</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Jourde-Chiche N, Costedoat-Chalumeau N, Baumstarck K, Loundou A, Bouillet L, Burtey S, et al.; WIN-Lupus study group. Weaning of maintenance immunosuppressive therapy in lupus nephritis (WIN-Lupus): Results of a multicentre randomised controlled trial. Ann Rheum Dis. 2022;81(10):1420-1427. doi: 10.1136/annrheumdis-2022-222435</mixed-citation><mixed-citation xml:lang="en">Jourde-Chiche N, Costedoat-Chalumeau N, Baumstarck K, Loundou A, Bouillet L, Burtey S, et al.; WIN-Lupus study group. Weaning of maintenance immunosuppressive therapy in lupus nephritis (WIN-Lupus): Results of a multicentre randomised controlled trial. Ann Rheum Dis. 2022;81(10):1420-1427. doi: 10.1136/annrheumdis-2022-222435</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Anutrakulchai S, Panaput T, Wongchinsri J, Chaishayanon S, Satirapoj B, Traitanon O, et al. A multicentre, randomised controlled study of enteric-coated mycophenolate sodium for the treatment of relapsed or resistant proliferative lupus nephritis: An Asian experience. Lupus Sci Med. 2016;3(1):e000120. doi: 10.1136/lupus-2015-000120</mixed-citation><mixed-citation xml:lang="en">Anutrakulchai S, Panaput T, Wongchinsri J, Chaishayanon S, Satirapoj B, Traitanon O, et al. A multicentre, randomised controlled study of enteric-coated mycophenolate sodium for the treatment of relapsed or resistant proliferative lupus nephritis: An Asian experience. Lupus Sci Med. 2016;3(1):e000120. doi: 10.1136/lupus-2015-000120</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Rivera F, Mérida E, Illescas ML, López-Rubio E, Frutos MA, García-Frías P, et al.; Glomerular Spanish Glomerular Study Group (GLOSEN). Mycophenolate in refractory and relapsing lupus nephritis. Am J Nephrol. 2014;40(2):105-112. doi: 10.1159/000365256</mixed-citation><mixed-citation xml:lang="en">Rivera F, Mérida E, Illescas ML, López-Rubio E, Frutos MA, García-Frías P, et al.; Glomerular Spanish Glomerular Study Group (GLOSEN). Mycophenolate in refractory and relapsing lupus nephritis. Am J Nephrol. 2014;40(2):105-112. doi: 10.1159/000365256</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Choi CB, Won S, Bae SC. Outcomes of multitarget therapy using mycophenolate mofetil and tacrolimus for refractory or relapsing lupus nephritis. Lupus. 2018;27(6):1007-1011. doi: 10.1177/0961203318758505</mixed-citation><mixed-citation xml:lang="en">Choi CB, Won S, Bae SC. Outcomes of multitarget therapy using mycophenolate mofetil and tacrolimus for refractory or relapsing lupus nephritis. Lupus. 2018;27(6):1007-1011. doi: 10.1177/0961203318758505</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Mok CC, To CH, Yu KL, Ho LY. Combined low-dose mycophenolate mofetil and tacrolimus for lupus nephritis with suboptimal response to standard therapy: A 12-month prospective study. Lupus. 2013;22(11):1135-1141. doi: 10.1177/0961203313502864</mixed-citation><mixed-citation xml:lang="en">Mok CC, To CH, Yu KL, Ho LY. Combined low-dose mycophenolate mofetil and tacrolimus for lupus nephritis with suboptimal response to standard therapy: A 12-month prospective study. Lupus. 2013;22(11):1135-1141. doi: 10.1177/0961203313502864</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Kasitanon N, Boripatkosol P, Louthrenoo W. Response to combination of mycophenolate mofetil, cyclosporin A and corticosteroid treatment in lupus nephritis patients with persistent proteinuria. Int J Rheum Dis. 2018;21(1):200-207. doi: 10.1111/1756-185X.13152</mixed-citation><mixed-citation xml:lang="en">Kasitanon N, Boripatkosol P, Louthrenoo W. Response to combination of mycophenolate mofetil, cyclosporin A and corticosteroid treatment in lupus nephritis patients with persistent proteinuria. Int J Rheum Dis. 2018;21(1):200-207. doi: 10.1111/1756-185X.13152</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Zhang J, Zhao Z, Hu X. Effect of rituximab on serum levels of anti-c1q and antineutrophil cytoplasmic autoantibodies in refractory severe lupus nephritis. Cell Biochem Biophys. 2015;72:197-201. doi: 10.1007/s12013-014-0437-z</mixed-citation><mixed-citation xml:lang="en">Zhang J, Zhao Z, Hu X. Effect of rituximab on serum levels of anti-c1q and antineutrophil cytoplasmic autoantibodies in refractory severe lupus nephritis. Cell Biochem Biophys. 2015;72:197-201. doi: 10.1007/s12013-014-0437-z</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Contis A, Vanquaethem H, Truchetet ME, Couzi L, Rigothier C, Richez C, et al. Analysis of the effectiveness and safety of rituximab in patients with refractory lupus nephritis: A chart review. Clin Rheumatol. 2016;35(2):517-522. doi: 10.1007/s10067-015-3166-9</mixed-citation><mixed-citation xml:lang="en">Contis A, Vanquaethem H, Truchetet ME, Couzi L, Rigothier C, Richez C, et al. Analysis of the effectiveness and safety of rituximab in patients with refractory lupus nephritis: A chart review. Clin Rheumatol. 2016;35(2):517-522. doi: 10.1007/s10067-015-3166-9</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Rovin BH, Solomons N, Pendergraft WF 3rd, Dooley MA, Tumlin J, Romero-Diaz J, et al. AURA-LV Study Group. A randomized, controlled double-blind study comparing the efficacy and safety of dose-ranging voclosporin with placebo in achieving remission in patients with active lupus nephritis. Kidney Int. 2019;95(1):219-231. doi: 10.1016/j.kint.2018.08.025</mixed-citation><mixed-citation xml:lang="en">Rovin BH, Solomons N, Pendergraft WF 3rd, Dooley MA, Tumlin J, Romero-Diaz J, et al. AURA-LV Study Group. A randomized, controlled double-blind study comparing the efficacy and safety of dose-ranging voclosporin with placebo in achieving remission in patients with active lupus nephritis. Kidney Int. 2019;95(1):219-231. doi: 10.1016/j.kint.2018.08.025</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Li Y, Palmisano M, Sun D, Zhou S. Pharmacokinetic disposition difference between cyclosporine and voclosporin drives their distinct efficacy and safety profiles in clinical studies. Clin Pharmacol. 2020;12:83-96. doi: 10.2147/CPAA.S255789</mixed-citation><mixed-citation xml:lang="en">Li Y, Palmisano M, Sun D, Zhou S. Pharmacokinetic disposition difference between cyclosporine and voclosporin drives their distinct efficacy and safety profiles in clinical studies. Clin Pharmacol. 2020;12:83-96. doi: 10.2147/CPAA.S255789</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Rovin BH, Solomons N, Pendergraft WF 3rd, Dooley MA, Tumlin J, Romero-Diaz J, et al.; AURA-LV Study Group. A randomized, controlled double-blind study comparing the efficacy and safety of dose-ranging voclosporin with placebo in achieving remission in patients with active lupus nephritis. Kidney Int. 2019;95(1):219-231. doi: 10.1016/j.kint.2018.08.025</mixed-citation><mixed-citation xml:lang="en">Rovin BH, Solomons N, Pendergraft WF 3rd, Dooley MA, Tumlin J, Romero-Diaz J, et al.; AURA-LV Study Group. A randomized, controlled double-blind study comparing the efficacy and safety of dose-ranging voclosporin with placebo in achieving remission in patients with active lupus nephritis. Kidney Int. 2019;95(1):219-231. doi: 10.1016/j.kint.2018.08.025</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Manzi S, Sánchez-Guerrero J, Merrill JT, Furie R, Gladman D, Navarra SV, et al.; BLISS-52 and BLISS-76 Study Groups. Effects of belimumab, a B lymphocyte stimulator-specific inhibitor, on disease activity across multiple organ domains in patients with systemic lupus erythematosus: Combined results from two phase III trials. Ann Rheum Dis. 2012;71(11):1833-1838. doi: 10.1136/annrheumdis-2011-200831</mixed-citation><mixed-citation xml:lang="en">Manzi S, Sánchez-Guerrero J, Merrill JT, Furie R, Gladman D, Navarra SV, et al.; BLISS-52 and BLISS-76 Study Groups. Effects of belimumab, a B lymphocyte stimulator-specific inhibitor, on disease activity across multiple organ domains in patients with systemic lupus erythematosus: Combined results from two phase III trials. Ann Rheum Dis. 2012;71(11):1833-1838. doi: 10.1136/annrheumdis-2011-200831</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Navarra SV, Guzmán RM, Gallacher AE, Hall S, Levy RA, Jimenez RE, et al.; BLISS-52 Study Group. Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: A randomised, placebo-controlled, phase 3 trial. Lancet. 2011;377(9767):721-731. doi: 10.1016/S0140-6736(10)61354-2</mixed-citation><mixed-citation xml:lang="en">Navarra SV, Guzmán RM, Gallacher AE, Hall S, Levy RA, Jimenez RE, et al.; BLISS-52 Study Group. Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: A randomised, placebo-controlled, phase 3 trial. Lancet. 2011;377(9767):721-731. doi: 10.1016/S0140-6736(10)61354-2</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Furie R, Rovin BH, Houssiau F, Malvar A, Teng YKO, Contreras G, et al. Two-year, randomized, controlled trial of belimumab in lupus nephritis. N Engl J Med. 2020;383(12):1117-1128. doi: 10.1056/NEJMoa2001180</mixed-citation><mixed-citation xml:lang="en">Furie R, Rovin BH, Houssiau F, Malvar A, Teng YKO, Contreras G, et al. Two-year, randomized, controlled trial of belimumab in lupus nephritis. N Engl J Med. 2020;383(12):1117-1128. doi: 10.1056/NEJMoa2001180</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Fanouriakis A, Tziolos N, Bertsias G, Boumpas DT. Update οn the diagnosis and management of systemic lupus erythematosus. Ann Rheum Dis. 2021;80(1):14-25. doi: 10.1136/annrheumdis-2020-218272</mixed-citation><mixed-citation xml:lang="en">Fanouriakis A, Tziolos N, Bertsias G, Boumpas DT. Update οn the diagnosis and management of systemic lupus erythematosus. Ann Rheum Dis. 2021;80(1):14-25. doi: 10.1136/annrheumdis-2020-218272</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Насонов ЕЛ, Попкова ТВ, Лила АМ. Белимумаб в лечении системной красной волчанки: 20 лет фундаментальных исследований, 10 лет клинической практики. Научно-практическая ревматология. 2021;59(4):367-383. doi: 10.47360/1995-4484-2021-367-383</mixed-citation><mixed-citation xml:lang="en">Nasonov EL, Popkova TV, Lila AM. Belimumab in the treatment of systemic lupus erythematosus: 20 years of basic research, 10 years of clinical practice. Nauchno-Prakticheskaya Revmatologia = Rheumatology Science and Practice. 2021;59(4):367-383 (In Russ.)]. doi: 10.47360/1995-4484-2021-367-383</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Асеева ЕА, Соловьев СК, Меснянкина АА, Цанян МЭ, Насонов ЕЛ. Опыт применения белимумаба у больных системной красной волчанкой. Научно-практическая ревматология. 2015;53(3):329-335. doi: 10.14412/1995-4484-2015-329-335</mixed-citation><mixed-citation xml:lang="en">Aseeva EA, Soloviev SK, Mesnyankina AA, Tsanyan ME, Nasonov EL. Experience with belimumab in patients with systemic lupus erythematosus. NauchnoPrakticheskaya Revmatologia = Rheumatology Science and Practice. 2015;53(3):329-335 (In Russ.)]. doi: 10.14412/1995-4484-2015-329-335</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Basu B, Roy B, Babu BG. Efficacy and safety of rituximab in comparison with common induction therapies in pediatric active lupus nephritis. Pediatr Nephrol. 2017;32(6):1013-1021. doi: 10.1007/s00467-017-3583-x</mixed-citation><mixed-citation xml:lang="en">Basu B, Roy B, Babu BG. Efficacy and safety of rituximab in comparison with common induction therapies in pediatric active lupus nephritis. Pediatr Nephrol. 2017;32(6):1013-1021. doi: 10.1007/s00467-017-3583-x</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Moroni G, Raffiotta F, Trezzi B, Giglio E, Mezzina N, Del Papa N, et al. Rituximab vs mycophenolate and vs cyclophosphamide pulses for induction therapy of active lupus nephritis: A clinical observational study. Rheumatology (Oxford). 2014;53(9):1570-1577. doi: 10.1093/rheumatology/ket462</mixed-citation><mixed-citation xml:lang="en">Moroni G, Raffiotta F, Trezzi B, Giglio E, Mezzina N, Del Papa N, et al. Rituximab vs mycophenolate and vs cyclophosphamide pulses for induction therapy of active lupus nephritis: A clinical observational study. Rheumatology (Oxford). 2014;53(9):1570-1577. doi: 10.1093/rheumatology/ket462</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Li K, Yu Y, Gao Y, Zhao F, Liang Z, Gao J. Comparative effectiveness of rituximab and common induction therapies for lupus nephritis: A systematic review and network meta-analysis. Front Immunol. 2022;13:859380. doi: 10.3389/fimmu.2022.859380</mixed-citation><mixed-citation xml:lang="en">Li K, Yu Y, Gao Y, Zhao F, Liang Z, Gao J. Comparative effectiveness of rituximab and common induction therapies for lupus nephritis: A systematic review and network meta-analysis. Front Immunol. 2022;13:859380. doi: 10.3389/fimmu.2022.859380</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Торгашина АВ, Соловьев СК, Александрова ЕН, РаденскаЛоповок СГ, Насонов ЕЛ. Применение ритуксимаба у больных волчаночным нефритом. Научно-практическая ревматология. 2010;48(4):14-26. doi: 10.14412/1995-4484-2010-1161</mixed-citation><mixed-citation xml:lang="en">Torgashina AV, Solovyev SK, Aleksandrova EN, Radenska-Lopovok SG, Nasonov EL. Use of rituximab in patients with lupus nephritis. Nauchno-Prakticheskaya Revmatologia = Rheumatology Science and Practice. 2010;48(4):14-26 (In Russ.)]. doi: 10.14412/1995-4484-2010-1161</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Цанян МЭ, Соловьев СК, Торгашина АВ, Александрова ЕН, Раденска-Лоповок СГ, Николаева ЕВ, и др. Эффективность терапии ритуксимабом у больных рефрактерной к стандартной терапии системной красной волчанкой при длительном динамическом наблюдении. Научно-практическая ревматология. 2014;52(2):159-168. doi: 10.14412/1995-4484-2014-159-168</mixed-citation><mixed-citation xml:lang="en">Tsanyan ME, Soloviev SK, Torgashina AV, Aleksandrova EN, Radenska-Lopovok SG, Nikolaeva EV, et al. Rituximab treatment efficacy in patients with systemic lupus erythematosus refractory to standard therapy in the long-term follow-up. Nauchno-Prakticheskaya Revmatologia = Rheumatology Science and Practice. 2014;52(2):159-168 (In Russ.)]. doi: 10.14412/1995-4484-2014-159-168</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Насонов ЕЛ. Перспективы анти-В-клеточной терапии в ревматологии. Научно-практическая ревматология. 2018;56(5):539-548. doi: 10.14412/1995-4484-2018-539-548</mixed-citation><mixed-citation xml:lang="en">Nasonov EL. Prospects for anti-B-cell therapy in rheumatology. Nauchno-Prakticheskaya Revmatologia = Rheumatology Science and Practice. 2018;56(5):539-548 (In Russ.)]. doi: 10.14412/1995-4484-2018-539-548</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Насонов ЕЛ, Авдеева АС. Иммуновоспалительные ревматические заболевания, связанные с интерфероном типа I: новые данные. Научно-практическая ревматология. 2019;57(4):452-461. doi: 10.14412/1995-4484-2019-452-461</mixed-citation><mixed-citation xml:lang="en">Nasonov EL, Avdeeva AS. Immunoinflammatory rheumatic diseases associated with type I interferon: New evidence. Nauchno-Prakticheskaya Revmatologia = Rheumatology Science and Practice. 2019;57(4):452-461 (In Russ.)]. doi: 10.14412/1995-4484-2019-452-461</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Rönnblom L, Alm GV, Eloranta ML. The type I interferon system in the development of lupus. Semin Immunol. 2011;23:113-121. doi: 10.1016/j.smim.2011.01.009</mixed-citation><mixed-citation xml:lang="en">Rönnblom L, Alm GV, Eloranta ML. The type I interferon system in the development of lupus. Semin Immunol. 2011;23:113-121. doi: 10.1016/j.smim.2011.01.009</mixed-citation></citation-alternatives></ref><ref id="cit51"><label>51</label><citation-alternatives><mixed-citation xml:lang="ru">Parikh SV, Rovin BH. Current and emerging therapies for lupus nephritis. J Am Soc Nephrol. 2016;27(10):2929-2939. doi: 10.1681/ASN.2016040415</mixed-citation><mixed-citation xml:lang="en">Parikh SV, Rovin BH. Current and emerging therapies for lupus nephritis. J Am Soc Nephrol. 2016;27(10):2929-2939. doi: 10.1681/ASN.2016040415</mixed-citation></citation-alternatives></ref><ref id="cit52"><label>52</label><citation-alternatives><mixed-citation xml:lang="ru">Feng X, Wu H, Grossman JM, Hanvivadhanakul P, FitzGerald JD, Park GS, et al. Association of increased interferon-inducible gene expression with disease activity and lupus nephritis in patients with systemic lupus erythematosus. Arthritis Rheum. 2006;54(9):2951-2962. doi: 10.1002/art.22044</mixed-citation><mixed-citation xml:lang="en">Feng X, Wu H, Grossman JM, Hanvivadhanakul P, FitzGerald JD, Park GS, et al. Association of increased interferon-inducible gene expression with disease activity and lupus nephritis in patients with systemic lupus erythematosus. Arthritis Rheum. 2006;54(9):2951-2962. doi: 10.1002/art.22044</mixed-citation></citation-alternatives></ref><ref id="cit53"><label>53</label><citation-alternatives><mixed-citation xml:lang="ru">Parikh SV, Malvar A, Song H, Alberton V, Lococo B, Vance J, et al. Characterising the immune profile of the kidney biopsy at lupus nephritis flare differentiates early treatment responders from non-responders. Lupus Sci Med. 2015;2(1):e000112. doi: 10.1136/lupus-2015-000112</mixed-citation><mixed-citation xml:lang="en">Parikh SV, Malvar A, Song H, Alberton V, Lococo B, Vance J, et al. Characterising the immune profile of the kidney biopsy at lupus nephritis flare differentiates early treatment responders from non-responders. Lupus Sci Med. 2015;2(1):e000112. doi: 10.1136/lupus-2015-000112</mixed-citation></citation-alternatives></ref><ref id="cit54"><label>54</label><citation-alternatives><mixed-citation xml:lang="ru">Morand EF, Furie R, Tanaka Y, Bruce IN, Askanase AD, Richez C, et al.; TULIP-2 Trial Investigators. Trial of anifrolumab in active systemic lupus erythematosus. N Engl J Med. 2020;382(3):211-221. doi: 10.1056/NEJMoa1912196</mixed-citation><mixed-citation xml:lang="en">Morand EF, Furie R, Tanaka Y, Bruce IN, Askanase AD, Richez C, et al.; TULIP-2 Trial Investigators. Trial of anifrolumab in active systemic lupus erythematosus. N Engl J Med. 2020;382(3):211-221. doi: 10.1056/NEJMoa1912196</mixed-citation></citation-alternatives></ref><ref id="cit55"><label>55</label><citation-alternatives><mixed-citation xml:lang="ru">Furie R, Khamashta M, Merrill JT, Werth VP, Kalunian K, Brohawn P, et al.; CD1013 Study Investigators. Anifrolumab, an antiinterferon-α receptor monoclonal antibody, in moderate-to-severe systemic lupus erythematosus. Arthritis Rheumatol. 2017;69(2):376-386. doi: 10.1002/art.39962</mixed-citation><mixed-citation xml:lang="en">Furie R, Khamashta M, Merrill JT, Werth VP, Kalunian K, Brohawn P, et al.; CD1013 Study Investigators. Anifrolumab, an antiinterferon-α receptor monoclonal antibody, in moderate-to-severe systemic lupus erythematosus. Arthritis Rheumatol. 2017;69(2):376-386. doi: 10.1002/art.39962</mixed-citation></citation-alternatives></ref><ref id="cit56"><label>56</label><citation-alternatives><mixed-citation xml:lang="ru">Hu W, Chen Y, Wang S, Chen H, Liu Z, Zeng C, et al. Clinicalmorphological features and outcomes of lupus podocytopathy. Clin J Am Soc Nephrol. 2016;11(4):585-592. doi: 10.2215/CJN.06720615</mixed-citation><mixed-citation xml:lang="en">Hu W, Chen Y, Wang S, Chen H, Liu Z, Zeng C, et al. Clinicalmorphological features and outcomes of lupus podocytopathy. Clin J Am Soc Nephrol. 2016;11(4):585-592. doi: 10.2215/CJN.06720615</mixed-citation></citation-alternatives></ref><ref id="cit57"><label>57</label><citation-alternatives><mixed-citation xml:lang="ru">Bomback AS, Markowitz GS. Lupus podocytopathy: A distinct entity. Clin J Am Soc Nephrol. 2016;11(4):547-548. doi: 10.2215/CJN.01880216</mixed-citation><mixed-citation xml:lang="en">Bomback AS, Markowitz GS. Lupus podocytopathy: A distinct entity. Clin J Am Soc Nephrol. 2016;11(4):547-548. doi: 10.2215/CJN.01880216</mixed-citation></citation-alternatives></ref><ref id="cit58"><label>58</label><citation-alternatives><mixed-citation xml:lang="ru">Oliva-Damaso N, Payan J, Oliva-Damaso E, Pereda T, Bomback AS. Lupus podocytopathy: An overview. Adv Chronic Kidney Dis. 2019;26(5):369-375. doi: 10.1053/j.ackd.2019.08.011</mixed-citation><mixed-citation xml:lang="en">Oliva-Damaso N, Payan J, Oliva-Damaso E, Pereda T, Bomback AS. Lupus podocytopathy: An overview. Adv Chronic Kidney Dis. 2019;26(5):369-375. doi: 10.1053/j.ackd.2019.08.011</mixed-citation></citation-alternatives></ref><ref id="cit59"><label>59</label><citation-alternatives><mixed-citation xml:lang="ru">Lionaki S, Liapis G, Vallianou K, Appel GB, D’Agati VD. The various forms of nephrotic syndrome in a patient with systemic lupus erythematosus. Case Rep Nephrol. 2020;2020:7869216. doi: 10.1155/2020/7869216</mixed-citation><mixed-citation xml:lang="en">Lionaki S, Liapis G, Vallianou K, Appel GB, D’Agati VD. The various forms of nephrotic syndrome in a patient with systemic lupus erythematosus. Case Rep Nephrol. 2020;2020:7869216. doi: 10.1155/2020/7869216</mixed-citation></citation-alternatives></ref><ref id="cit60"><label>60</label><citation-alternatives><mixed-citation xml:lang="ru">Dube GK, Markowitz GS, Radhakrishnan J, Appel GB, D’Agati VD. Minimal change disease in systemic lupus erythematosus. Clin Nephrol. 2002;57(2):120-126. doi: 10.5414/cnp57120</mixed-citation><mixed-citation xml:lang="en">Dube GK, Markowitz GS, Radhakrishnan J, Appel GB, D’Agati VD. Minimal change disease in systemic lupus erythematosus. Clin Nephrol. 2002;57(2):120-126. doi: 10.5414/cnp57120</mixed-citation></citation-alternatives></ref><ref id="cit61"><label>61</label><citation-alternatives><mixed-citation xml:lang="ru">Hertig A, Droz D, Lesavre P, Grünfeld JP, Rieu P. SLE and idiopathic nephrotic syndrome: Coincidence or not? Am J Kidney Dis. 2002;40(6):1179-1184. doi: 10.1053/ajkd.2002.36875</mixed-citation><mixed-citation xml:lang="en">Hertig A, Droz D, Lesavre P, Grünfeld JP, Rieu P. SLE and idiopathic nephrotic syndrome: Coincidence or not? Am J Kidney Dis. 2002;40(6):1179-1184. doi: 10.1053/ajkd.2002.36875</mixed-citation></citation-alternatives></ref><ref id="cit62"><label>62</label><citation-alternatives><mixed-citation xml:lang="ru">Kraft SW, Schwartz MM, Korbet SM, Lewis EJ. Glomerular podocytopathy in patients with systemic lupus erythematosus. J Am Soc Nephrol. 2005;16(1):175-179. doi: 10.1681/ASN.2004050350</mixed-citation><mixed-citation xml:lang="en">Kraft SW, Schwartz MM, Korbet SM, Lewis EJ. Glomerular podocytopathy in patients with systemic lupus erythematosus. J Am Soc Nephrol. 2005;16(1):175-179. doi: 10.1681/ASN.2004050350</mixed-citation></citation-alternatives></ref><ref id="cit63"><label>63</label><citation-alternatives><mixed-citation xml:lang="ru">Bomback AS. Nonproliferative forms of lupus nephritis: An overview. Rheum Dis Clin North Am. 2018;44(4):561-569. doi: 10.1016/j.rdc.2018.06.003</mixed-citation><mixed-citation xml:lang="en">Bomback AS. Nonproliferative forms of lupus nephritis: An overview. Rheum Dis Clin North Am. 2018;44(4):561-569. doi: 10.1016/j.rdc.2018.06.003</mixed-citation></citation-alternatives></ref><ref id="cit64"><label>64</label><citation-alternatives><mixed-citation xml:lang="ru">KDIGO. Clinical practice guideline for the management of glomerular diseases. Kidney Int. 2021;100:1-276. doi: 10.1016/j.kint.2021.05.021</mixed-citation><mixed-citation xml:lang="en">KDIGO. Clinical practice guideline for the management of glomerular diseases. Kidney Int. 2021;100:1-276. doi: 10.1016/j.kint.2021.05.021</mixed-citation></citation-alternatives></ref><ref id="cit65"><label>65</label><citation-alternatives><mixed-citation xml:lang="ru">Bendapudi PK, Hurwitz S, Fry A, Marques MB, Waldo SW, Li A, et al. Derivation and external validation of the PLASMIC score for rapid assessment of adults with thrombotic microangiopathies: A cohort study. Lancet Haematol. 2017;4(4):e157-e164. doi: 10.1016/S2352-3026(17)30026-1</mixed-citation><mixed-citation xml:lang="en">Bendapudi PK, Hurwitz S, Fry A, Marques MB, Waldo SW, Li A, et al. Derivation and external validation of the PLASMIC score for rapid assessment of adults with thrombotic microangiopathies: A cohort study. Lancet Haematol. 2017;4(4):e157-e164. doi: 10.1016/S2352-3026(17)30026-1</mixed-citation></citation-alternatives></ref><ref id="cit66"><label>66</label><citation-alternatives><mixed-citation xml:lang="ru">von Baeyer H. Plasmapheresis in thrombotic microangiopathy associated syndromes: Review of outcome data derived from clinical trials and open studies. Ther Apher. 2002;6(4):320-328. doi: 10.1046/j.1526-0968.2002.00390.x</mixed-citation><mixed-citation xml:lang="en">von Baeyer H. Plasmapheresis in thrombotic microangiopathy associated syndromes: Review of outcome data derived from clinical trials and open studies. Ther Apher. 2002;6(4):320-328. doi: 10.1046/j.1526-0968.2002.00390.x</mixed-citation></citation-alternatives></ref><ref id="cit67"><label>67</label><citation-alternatives><mixed-citation xml:lang="ru">Allford SL, Hunt BJ, Rose P, Machin SJ. Guidelines on the diagnosis and management of the thrombotic microangiopathic haemolytic anaemias. Br J Haematol. 2003;120(4):556-573. doi: 10.1046/j.1365-2141.2003.04049.x</mixed-citation><mixed-citation xml:lang="en">Allford SL, Hunt BJ, Rose P, Machin SJ. Guidelines on the diagnosis and management of the thrombotic microangiopathic haemolytic anaemias. Br J Haematol. 2003;120(4):556-573. doi: 10.1046/j.1365-2141.2003.04049.x</mixed-citation></citation-alternatives></ref><ref id="cit68"><label>68</label><citation-alternatives><mixed-citation xml:lang="ru">Westwood JP, Thomas M, Alwan F, McDonald V, Benjamin S, Lester WA, et al. Rituximab prophylaxis to prevent thrombotic thrombocytopenic purpura relapse: Outcome and evaluation of dosing regimens. Blood Adv. 2017;1(15):1159-1166. doi: 10.1182/bloodadvances.2017008268</mixed-citation><mixed-citation xml:lang="en">Westwood JP, Thomas M, Alwan F, McDonald V, Benjamin S, Lester WA, et al. Rituximab prophylaxis to prevent thrombotic thrombocytopenic purpura relapse: Outcome and evaluation of dosing regimens. Blood Adv. 2017;1(15):1159-1166. doi: 10.1182/bloodadvances.2017008268</mixed-citation></citation-alternatives></ref><ref id="cit69"><label>69</label><citation-alternatives><mixed-citation xml:lang="ru">Froissart A, Buffet M, Veyradier A, Poullin P, Provôt F, Malot S, et al.; French Thrombotic Microangiopathies Reference Center. Efficacy and safety of first-line rituximab in severe, acquired thrombotic thrombocytopenic purpura with a suboptimal response to plasma exchange. Experience of the French Thrombotic Microangiopathies Reference Center. Crit Care Med. 2012;40(1):104-111. doi: 10.1097/CCM.0b013e31822e9d66</mixed-citation><mixed-citation xml:lang="en">Froissart A, Buffet M, Veyradier A, Poullin P, Provôt F, Malot S, et al.; French Thrombotic Microangiopathies Reference Center. Efficacy and safety of first-line rituximab in severe, acquired thrombotic thrombocytopenic purpura with a suboptimal response to plasma exchange. Experience of the French Thrombotic Microangiopathies Reference Center. Crit Care Med. 2012;40(1):104-111. doi: 10.1097/CCM.0b013e31822e9d66</mixed-citation></citation-alternatives></ref><ref id="cit70"><label>70</label><citation-alternatives><mixed-citation xml:lang="ru">Scully M, Cohen H, Cavenagh J, Benjamin S, Starke R, Killick S, et al. Remission in acute refractory and relapsing thrombotic thrombocytopenic purpura following rituximab is associated with a reduction in IgG antibodies to ADAMTS-13. Br J Haematol. 2007;136(3):451-461. doi: 10.1111/j.1365-2141.2006.06448.x</mixed-citation><mixed-citation xml:lang="en">Scully M, Cohen H, Cavenagh J, Benjamin S, Starke R, Killick S, et al. Remission in acute refractory and relapsing thrombotic thrombocytopenic purpura following rituximab is associated with a reduction in IgG antibodies to ADAMTS-13. Br J Haematol. 2007;136(3):451-461. doi: 10.1111/j.1365-2141.2006.06448.x</mixed-citation></citation-alternatives></ref><ref id="cit71"><label>71</label><citation-alternatives><mixed-citation xml:lang="ru">Scully M, McDonald V, Cavenagh J, Longair I, Cohen H, Machin SJ. A phase 2 study of the safety and efficacy of rituximab with plasma exchange in acute acquired thrombotic thrombocytopenic purpura. Blood. 2011;118:1746-1753. doi: 10.1182/blood-2011-03-341131</mixed-citation><mixed-citation xml:lang="en">Scully M, McDonald V, Cavenagh J, Longair I, Cohen H, Machin SJ. A phase 2 study of the safety and efficacy of rituximab with plasma exchange in acute acquired thrombotic thrombocytopenic purpura. Blood. 2011;118:1746-1753. doi: 10.1182/blood-2011-03-341131</mixed-citation></citation-alternatives></ref><ref id="cit72"><label>72</label><citation-alternatives><mixed-citation xml:lang="ru">Peyvandi F, Scully M, Kremer Hovinga JA, Cataland S, Knöbl P, Wu H, et al.; TITAN Investigators. Caplacizumab for acquired thrombotic thrombocytopenic purpura. N Engl J Med. 2016;374(6):511-522. doi: 10.1056/NEJMoa1505533</mixed-citation><mixed-citation xml:lang="en">Peyvandi F, Scully M, Kremer Hovinga JA, Cataland S, Knöbl P, Wu H, et al.; TITAN Investigators. Caplacizumab for acquired thrombotic thrombocytopenic purpura. N Engl J Med. 2016;374(6):511-522. doi: 10.1056/NEJMoa1505533</mixed-citation></citation-alternatives></ref><ref id="cit73"><label>73</label><citation-alternatives><mixed-citation xml:lang="ru">Scully M, Cataland SR, Peyvandi F, Coppo P, Knöbl P, Kremer Hovinga JA, et al.; HERCULES Investigators. Caplacizumab treatment for acquired thrombotic thrombocytopenic purpura. N Engl J Med. 2019;380(4):335-346. doi: 10.1056/NEJMoa1806311</mixed-citation><mixed-citation xml:lang="en">Scully M, Cataland SR, Peyvandi F, Coppo P, Knöbl P, Kremer Hovinga JA, et al.; HERCULES Investigators. Caplacizumab treatment for acquired thrombotic thrombocytopenic purpura. N Engl J Med. 2019;380(4):335-346. doi: 10.1056/NEJMoa1806311</mixed-citation></citation-alternatives></ref><ref id="cit74"><label>74</label><citation-alternatives><mixed-citation xml:lang="ru">Sciascia S, Yazdany J, Dall’Era M, Fenoglio R, Radin M, Aggarwal I, et al. Anticoagulation in patients with concomitant lupus nephritis and thrombotic microangiopathy: A multicentre cohort study. Ann Rheum Dis. 2019;78(7):1004-1006. doi: 10.1136/annrheumdis-2018-214559</mixed-citation><mixed-citation xml:lang="en">Sciascia S, Yazdany J, Dall’Era M, Fenoglio R, Radin M, Aggarwal I, et al. Anticoagulation in patients with concomitant lupus nephritis and thrombotic microangiopathy: A multicentre cohort study. Ann Rheum Dis. 2019;78(7):1004-1006. doi: 10.1136/annrheumdis-2018-214559</mixed-citation></citation-alternatives></ref><ref id="cit75"><label>75</label><citation-alternatives><mixed-citation xml:lang="ru">Tektonidou MG. Antiphospholipid syndrome nephropathy: From pathogenesis to treatment. Front Immunol. 2018;9: 1181. doi: 10.3389/fimmu.2018.01181</mixed-citation><mixed-citation xml:lang="en">Tektonidou MG. Antiphospholipid syndrome nephropathy: From pathogenesis to treatment. Front Immunol. 2018;9: 1181. doi: 10.3389/fimmu.2018.01181</mixed-citation></citation-alternatives></ref><ref id="cit76"><label>76</label><citation-alternatives><mixed-citation xml:lang="ru">Dufrost V, Risse J, Reshetnyak T, Satybaldyeva M, Du Y, Yan XX, et al. Increased risk of thrombosis in antiphospholipid syndrome patients treated with direct oral anticoagulants. Results from an international patient-level data meta-analysis. Autoimmun Rev. 2018;17(10):1011-1021. doi: 10.1016/j.autrev.2018.04.009</mixed-citation><mixed-citation xml:lang="en">Dufrost V, Risse J, Reshetnyak T, Satybaldyeva M, Du Y, Yan XX, et al. Increased risk of thrombosis in antiphospholipid syndrome patients treated with direct oral anticoagulants. Results from an international patient-level data meta-analysis. Autoimmun Rev. 2018;17(10):1011-1021. doi: 10.1016/j.autrev.2018.04.009</mixed-citation></citation-alternatives></ref><ref id="cit77"><label>77</label><citation-alternatives><mixed-citation xml:lang="ru">Pengo V, Denas G, Zoppellaro G, Jose SP, Hoxha A, Ruffatti A, et al. Rivaroxaban vs warfarin in high-risk patients with antiphospholipid syndrome. Blood. 2018;132(13):1365-1371. doi: 10.1182/blood-2018-04-848333</mixed-citation><mixed-citation xml:lang="en">Pengo V, Denas G, Zoppellaro G, Jose SP, Hoxha A, Ruffatti A, et al. Rivaroxaban vs warfarin in high-risk patients with antiphospholipid syndrome. Blood. 2018;132(13):1365-1371. doi: 10.1182/blood-2018-04-848333</mixed-citation></citation-alternatives></ref><ref id="cit78"><label>78</label><citation-alternatives><mixed-citation xml:lang="ru">Kazzaz NM, McCune WJ, Knight JS. Treatment of catastrophic antiphospholipid syndrome. Curr Opin Rheumatol. 2016;28:218-227. doi: 10.1097/BOR.0000000000000269</mixed-citation><mixed-citation xml:lang="en">Kazzaz NM, McCune WJ, Knight JS. Treatment of catastrophic antiphospholipid syndrome. Curr Opin Rheumatol. 2016;28:218-227. doi: 10.1097/BOR.0000000000000269</mixed-citation></citation-alternatives></ref><ref id="cit79"><label>79</label><citation-alternatives><mixed-citation xml:lang="ru">Kronbichler A, Brezina B, Quintana LF, Jayne DR. Efficacy of plasma exchange and immunoadsorption in systemic lupus erythematosus and antiphospholipid syndrome: A systematic review. Autoimmun Rev. 2016;15(1):38-49. doi: 10.1016/j.autrev.2015.08.010</mixed-citation><mixed-citation xml:lang="en">Kronbichler A, Brezina B, Quintana LF, Jayne DR. Efficacy of plasma exchange and immunoadsorption in systemic lupus erythematosus and antiphospholipid syndrome: A systematic review. Autoimmun Rev. 2016;15(1):38-49. doi: 10.1016/j.autrev.2015.08.010</mixed-citation></citation-alternatives></ref><ref id="cit80"><label>80</label><citation-alternatives><mixed-citation xml:lang="ru">Bucciarelli S, Espinosa G, Cervera R, Erkan D, Gómez-Puerta JA, Ramos-Casals M, et al.; European Forum on Antiphospholipid Antibodies. Mortality in the catastrophic antiphospholipid syndrome: Causes of death and prognostic factors in a series of 250 patients. Arthritis Rheum. 2006;54(8):2568-2576. doi: 10.1002/art.22018</mixed-citation><mixed-citation xml:lang="en">Bucciarelli S, Espinosa G, Cervera R, Erkan D, Gómez-Puerta JA, Ramos-Casals M, et al.; European Forum on Antiphospholipid Antibodies. Mortality in the catastrophic antiphospholipid syndrome: Causes of death and prognostic factors in a series of 250 patients. Arthritis Rheum. 2006;54(8):2568-2576. doi: 10.1002/art.22018</mixed-citation></citation-alternatives></ref><ref id="cit81"><label>81</label><citation-alternatives><mixed-citation xml:lang="ru">Diószegi Á, Tarr T, Nagy-Vincze M, Nánásy-Vass M, Veisz R, Bidiga L, et al. Microthrombotic renal involvement in an SLE patient with concomitant catastrophic antiphospholipid syndrome: The beneficial effect of rituximab treatment. Lupus. 2018;27(9):1552-1558. doi: 10.1177/0961203318768890</mixed-citation><mixed-citation xml:lang="en">Diószegi Á, Tarr T, Nagy-Vincze M, Nánásy-Vass M, Veisz R, Bidiga L, et al. Microthrombotic renal involvement in an SLE patient with concomitant catastrophic antiphospholipid syndrome: The beneficial effect of rituximab treatment. Lupus. 2018;27(9):1552-1558. doi: 10.1177/0961203318768890</mixed-citation></citation-alternatives></ref><ref id="cit82"><label>82</label><citation-alternatives><mixed-citation xml:lang="ru">Rymarz A, Niemczyk S. The complex treatment including rituximab in the management of catastrophic antiphospholid syndrome with renal involvement. BMC Nephrol. 2018;19:132. doi: 10.1186/s12882-018-0928-z</mixed-citation><mixed-citation xml:lang="en">Rymarz A, Niemczyk S. The complex treatment including rituximab in the management of catastrophic antiphospholid syndrome with renal involvement. BMC Nephrol. 2018;19:132. doi: 10.1186/s12882-018-0928-z</mixed-citation></citation-alternatives></ref><ref id="cit83"><label>83</label><citation-alternatives><mixed-citation xml:lang="ru">Guillot M, Rafat C, Buob D, Coppo P, Jamme M, Rondeau E, et al. Eculizumab for catastrophic antiphospholipid syndrome – A case report and literature review. Rheumatology (Oxford). 2018;57(11):2055-2057. doi: 10.1093/rheumatology/key228</mixed-citation><mixed-citation xml:lang="en">Guillot M, Rafat C, Buob D, Coppo P, Jamme M, Rondeau E, et al. Eculizumab for catastrophic antiphospholipid syndrome – A case report and literature review. Rheumatology (Oxford). 2018;57(11):2055-2057. doi: 10.1093/rheumatology/key228</mixed-citation></citation-alternatives></ref><ref id="cit84"><label>84</label><citation-alternatives><mixed-citation xml:lang="ru">Ruffatti A, Tarzia V, Fedrigo M, Calligaro A, Favaro M, Macor P, et al. Evidence of complement activation in the thrombotic small vessels of a patient with catastrophic antiphospholipid syndrome treated with eculizumab. Autoimmun Rev. 2019;18(5):561-563. doi: 10.1016/j.autrev.2019.03.015</mixed-citation><mixed-citation xml:lang="en">Ruffatti A, Tarzia V, Fedrigo M, Calligaro A, Favaro M, Macor P, et al. Evidence of complement activation in the thrombotic small vessels of a patient with catastrophic antiphospholipid syndrome treated with eculizumab. Autoimmun Rev. 2019;18(5):561-563. doi: 10.1016/j.autrev.2019.03.015</mixed-citation></citation-alternatives></ref><ref id="cit85"><label>85</label><citation-alternatives><mixed-citation xml:lang="ru">Tinti MG, Carnevale V, Inglese M, Molinaro F, Bernal M, Migliore A, et al. Eculizumab in refractory catastrophic antiphospholipid syndrome: A case report and systematic review of the literature. Clin Exp Med. 2019;19(3):281-288. doi: 10.1007/s10238-019-00565-8</mixed-citation><mixed-citation xml:lang="en">Tinti MG, Carnevale V, Inglese M, Molinaro F, Bernal M, Migliore A, et al. Eculizumab in refractory catastrophic antiphospholipid syndrome: A case report and systematic review of the literature. Clin Exp Med. 2019;19(3):281-288. doi: 10.1007/s10238-019-00565-8</mixed-citation></citation-alternatives></ref><ref id="cit86"><label>86</label><citation-alternatives><mixed-citation xml:lang="ru">Cavero T, Rabasco C, López A, Román E, Ávila A, Sevillano Á, et al. Eculizumab in secondary atypical haemolytic uraemic syndrome. Nephrol Dial Transplant. 2017;32(3):466-474. doi: 10.1093/ndt/gfw453</mixed-citation><mixed-citation xml:lang="en">Cavero T, Rabasco C, López A, Román E, Ávila A, Sevillano Á, et al. Eculizumab in secondary atypical haemolytic uraemic syndrome. Nephrol Dial Transplant. 2017;32(3):466-474. doi: 10.1093/ndt/gfw453</mixed-citation></citation-alternatives></ref><ref id="cit87"><label>87</label><citation-alternatives><mixed-citation xml:lang="ru">Palma LMP, Sridharan M, Sethi S. Complement in secondary thrombotic microangiopathy. Kidney Int Rep. 2021;6:11-23. doi: 10.1016/j.ekir.2020.10.009</mixed-citation><mixed-citation xml:lang="en">Palma LMP, Sridharan M, Sethi S. Complement in secondary thrombotic microangiopathy. Kidney Int Rep. 2021;6:11-23. doi: 10.1016/j.ekir.2020.10.009</mixed-citation></citation-alternatives></ref><ref id="cit88"><label>88</label><citation-alternatives><mixed-citation xml:lang="ru">Legendre CM, Licht C, Muus P, Greenbaum LA, Babu S, Bedrosian C, et al. Terminal complement inhibitor eculizumab in atypical hemolytic-uremic syndrome. N Engl J Med. 2013;368(23):2169-2181. doi: 10.1056/NEJMoa1208981</mixed-citation><mixed-citation xml:lang="en">Legendre CM, Licht C, Muus P, Greenbaum LA, Babu S, Bedrosian C, et al. Terminal complement inhibitor eculizumab in atypical hemolytic-uremic syndrome. N Engl J Med. 2013;368(23):2169-2181. doi: 10.1056/NEJMoa1208981</mixed-citation></citation-alternatives></ref><ref id="cit89"><label>89</label><citation-alternatives><mixed-citation xml:lang="ru">de Holanda MI, Porto LC, Wagner T, Christiani LF, Palma LMP. Use of eculizumab in a systemic lupus erythemathosus patient presenting thrombotic microangiopathy and heterozygous deletion in CFHR1-CFHR3. A case report and systematic review. Clin Rheumatol. 2017;36:2859-2867. doi: 10.1007/s10067-017-3823-2</mixed-citation><mixed-citation xml:lang="en">de Holanda MI, Porto LC, Wagner T, Christiani LF, Palma LMP. Use of eculizumab in a systemic lupus erythemathosus patient presenting thrombotic microangiopathy and heterozygous deletion in CFHR1-CFHR3. A case report and systematic review. Clin Rheumatol. 2017;36:2859-2867. doi: 10.1007/s10067-017-3823-2</mixed-citation></citation-alternatives></ref><ref id="cit90"><label>90</label><citation-alternatives><mixed-citation xml:lang="ru">Sciascia S, Radin M, Yazdany J, Tektonidou M, Cecchi I, Roccatello D, et al. Expanding the therapeutic options for renal involvement in lupus: Eculizumab, available evidence. Rheumatol Int. 2017;37(8):1249-1255. doi: 10.1007/s00296-017-3686-5</mixed-citation><mixed-citation xml:lang="en">Sciascia S, Radin M, Yazdany J, Tektonidou M, Cecchi I, Roccatello D, et al. Expanding the therapeutic options for renal involvement in lupus: Eculizumab, available evidence. Rheumatol Int. 2017;37(8):1249-1255. doi: 10.1007/s00296-017-3686-5</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
