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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rsp</journal-id><journal-title-group><journal-title xml:lang="ru">Научно-практическая ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Rheumatology Science and Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-4484</issn><issn pub-type="epub">1995-4492</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.47360/1995-4484-2024-484-493</article-id><article-id custom-type="elpub" pub-id-type="custom">rsp-3634</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS AND LECTURES</subject></subj-group></article-categories><title-group><article-title>Применение ультразвукового исследования для оценки интерстициального заболевания легких у больных ревматическими заболеваниями</article-title><trans-title-group xml:lang="en"><trans-title>Use of ultrasound to evaluation interstitial lung disease in rheumatic disease</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2667-4284</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Овсянникова</surname><given-names>О. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Ovsyannikova</surname><given-names>O. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Овсянникова Ольга Борисовна</p><p>115522, Москва, Каширское шоссе, 34а</p></bio><bio xml:lang="en"><p>Olga Ovsyannikova</p><p>115522, Moscow, Kashirskoye Highway, 34A</p></bio><email xlink:type="simple">sorry_84@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3650-7658</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Конева</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Koneva</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34а</p></bio><bio xml:lang="en"><p>115522, Moscow, Kashirskoye Highway, 34A</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5012-0540</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гарзанова</surname><given-names>Л. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Garzanova</surname><given-names>L. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34а</p></bio><bio xml:lang="en"><p>115522, Moscow, Kashirskoye Highway, 34A</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3248-6426</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ананьева</surname><given-names>Л. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Ananyeva</surname><given-names>L. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34а</p></bio><bio xml:lang="en"><p>115522, Moscow, Kashirskoye Highway, 34A</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «НФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.A. Nasonova Research Institute of Rheumatology</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>31</day><month>10</month><year>2024</year></pub-date><volume>62</volume><issue>5</issue><fpage>484</fpage><lpage>493</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Овсянникова О.Б., Конева О.А., Гарзанова Л.А., Ананьева Л.П., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Овсянникова О.Б., Конева О.А., Гарзанова Л.А., Ананьева Л.П.</copyright-holder><copyright-holder xml:lang="en">Ovsyannikova O.B., Koneva O.A., Garzanova L.A., Ananyeva L.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://rsp.mediar-press.net/rsp/article/view/3634">https://rsp.mediar-press.net/rsp/article/view/3634</self-uri><abstract><p>Интерстициальное заболевание легких является одним из самых частых внесуставных проявлений иммуновоспалительных ревматических заболеваний и одной из самых частых причин тяжелого течения заболевания и смертности. Ранняя диагностика и мониторинг пациентов с риском прогрессирования имеют решающее значение для своевременного назначения иммуномодулирующей и антифиброзной терапии, потенциально способной изменить течение заболевания. Компьютерная томография высокого разрешения является стандартным методом лучевой диагностики поражения легких у пациентов с респираторными синдромами или нарушениями по данным функциональных легочных тестов. Она способна выявить изменения в легких до того, как они станут заметны при рентгенографии. Ультразвуковое исследование (УЗИ) легких используется относительно недавно как безопасный и легкодоступный метод для выявления фиброза легких, бронхиолита или пневмоторакса. К сонографическим скрининговым признакам поражения легких относятся В-линии, неровность плевральной линии или отсутствие скольжения плевральной линии. В данном контексте увеличивающееся количество работ по изучению и валидации УЗИ легких характеризует его как привлекательный инструмент для оценки легочной патологии.</p></abstract><trans-abstract xml:lang="en"><p>Interstitial lung disease is one of the most relevant extra-articular manifestations of rheumatic diseases resulting in a substantial increase in morbidity and mortality. Early diagnosis and close monitoring to identify patients at risk of progression are crucial to establish the need for targeted treatment with immunomodulatory and antifibrotic drugs, with potential ability to change the course of the disease. High resolution computed tomography (HRCT) is the standard radiographic technique to diagnose lung involvement in patients suffering from respiratory symptoms or presenting with a pathological pulmonary function test. HRCT is able to detect changes in the lung before they are apparent on conventional X-ray. Recently, sonography of the lung was introduced as a safe and easily available method for detecting lung fibrosis, bronchiolitis or pneumothorax Sonographic signs like tissue B-lines, irregularities of the pleura or the absence of lung sliding might be a suitable screening tool for lung involvement. In this context, lung ultrasound (LUS) is an attractive tool in a growing research and validation process.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ультразвуковое исследование</kwd><kwd>иммуновоспалительные ревматические заболевания</kwd><kwd>интерстициальное заболевание легких</kwd></kwd-group><kwd-group xml:lang="en"><kwd>ultrasound</kwd><kwd>rheumatic disease</kwd><kwd>interstitial lung disease</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Статья подготовлена в рамках научной темы (регистрационный номер ИКБРС 0397-2020-0006).</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Насонов ЕЛ (ред.). Ревматология. Российские клинические рекомендации. М.:ГЭОТАР-Медиа;2020.</mixed-citation><mixed-citation xml:lang="en">Nasonov EL (ed.). Rheumatology. Russian clinical recommendations. Moscow:GEOTAR-Media;2020 (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Hofmann-Vold AM, Molberg Ø. Detection, screening, and classification of interstitial lung disease in patients with systemic sclerosis. Curr Opin Rheumatol. 2020;32:497-504. doi: 10.1097/BOR.0000000000000741</mixed-citation><mixed-citation xml:lang="en">Hofmann-Vold AM, Molberg Ø. Detection, screening, and classification of interstitial lung disease in patients with systemic sclerosis. Curr Opin Rheumatol. 2020;32:497-504. doi: 10.1097/BOR.0000000000000741</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Castillo S, Forbes B, Chen J, Hamblin MJ. Assessment of optimal screening tests for the detection of an inflammatory myositis-associated interstitial lung disease. Cureus. 2020;12:7875. doi: 10.7759/cureus.7875</mixed-citation><mixed-citation xml:lang="en">Castillo S, Forbes B, Chen J, Hamblin MJ. Assessment of optimal screening tests for the detection of an inflammatory myositis-associated interstitial lung disease. Cureus. 2020;12:7875. doi: 10.7759/cureus.7875</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Barskova T, Gargani L, Guiducci S, Randone SB, Bruni C, Carnesecchi G, et al. Lung ultrasound for the screening of interstitial lung disease in very early systemic sclerosis. Ann Rheum Dis. 2013;72(3):390-395. doi: 10.1136/annrheumdis-2011-201072</mixed-citation><mixed-citation xml:lang="en">Barskova T, Gargani L, Guiducci S, Randone SB, Bruni C, Carnesecchi G, et al. Lung ultrasound for the screening of interstitial lung disease in very early systemic sclerosis. Ann Rheum Dis. 2013;72(3):390-395. doi: 10.1136/annrheumdis-2011-201072</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Gutierrez M, Soto-Fajardo C, Pineda C, Alfaro-Rodriguez A, Terslev L, Bruyn GA, et al. Ultrasound in the assessment of interstitial lung disease in systemic sclerosis: A systematic literature review by the OMERACT Ultrasound Group. J Rheumatol. 2020;47(7):991-1000. doi: 10.3899/jrheum.180940</mixed-citation><mixed-citation xml:lang="en">Gutierrez M, Soto-Fajardo C, Pineda C, Alfaro-Rodriguez A, Terslev L, Bruyn GA, et al. Ultrasound in the assessment of interstitial lung disease in systemic sclerosis: A systematic literature review by the OMERACT Ultrasound Group. J Rheumatol. 2020;47(7):991-1000. doi: 10.3899/jrheum.180940</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Овсянникова ОБ, Ананьева ЛП, Корсакова ЮО, Конева ОА, Волков АВ, Глухова СИ. Оценка ультразвукового сканирования легких у больных системной склеродермией и интерстициальным поражением легких. Научно-практическая ревматология. 2013;51(3):279-284.</mixed-citation><mixed-citation xml:lang="en">Ovsyannikova OB, Ananyeva LP, Korsakova YuO, Koneva OA, Volkov AV, Glukhova SI. Assessment of lung ultrasound in patients with scleroderma systematica and interstitial lung disease. Nauchno-Prakticheskaya Revmatologia = Rheumatology Science and Practice. 2013;51(3):279-284 (In Russ.). doi: 10.14412/1995-4484-2013-1502</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Овсянникова ОБ, Ананьева ЛП, Конева ОА, Десинова ОВ, Старовойтова МН. Ультразвуковое сканирование: возможности и перспективы для оценки поражения легких при системной склеродермии. Научно-практическая ревматология. 2012;50(6): 80-87.</mixed-citation><mixed-citation xml:lang="en">Ovsyannikova OB, Ananyeva LP, Koneva OA, Desinova OV, Starovoitova MN. Ultrasound scanning: Possibilities and prospects of evaluating lung involvement in systemic scleroderma. Nauchno-Prakticheskaya Revmatologia = Rheumatology Science and Practice. 2012;50(6):80-87. (In Russ.). doi: 10.14412/1995-4484-2012-1298</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Moazedi-Fuerst FC, Kielhauser SM, Scheidl S, Tripolt NJ, Lutfi A, Yazdani-Biuki B, et al. Ultrasound screening for interstitial lung disease in rheumatoid arthritis. Clin Exp Rheumatol. 2014;32(2):199-203.</mixed-citation><mixed-citation xml:lang="en">Moazedi-Fuerst FC, Kielhauser SM, Scheidl S, Tripolt NJ, Lutfi A, Yazdani-Biuki B, et al. Ultrasound screening for interstitial lung disease in rheumatoid arthritis. Clin Exp Rheumatol. 2014;32(2):199-203.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Cogliati C, Antivalle M, Torzillo D, Birocchi S, Norsa A, Bianco R, et al. Standard and pocket-size lung ultrasound devices can detect interstitial lung disease in rheumatoid arthritis patients. Rheumatology (Oxford). 2014;53(8):1497-1503. doi: 10.1093/rheumatology/keu033</mixed-citation><mixed-citation xml:lang="en">Cogliati C, Antivalle M, Torzillo D, Birocchi S, Norsa A, Bianco R, et al. Standard and pocket-size lung ultrasound devices can detect interstitial lung disease in rheumatoid arthritis patients. Rheumatology (Oxford). 2014;53(8):1497-1503. doi: 10.1093/rheumatology/keu033</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Fotoh DS, Helal A, Rizk MS, Esaily HA. Serum Krebs von den Lungen-6 and lung ultrasound B lines as potential diagnostic and prognostic factors for rheumatoid arthritis-associated interstitial lung disease. Clin Rheumatol. 2021;40(7):2689-2697. doi: 10.1007/s10067-021-05585-y</mixed-citation><mixed-citation xml:lang="en">Fotoh DS, Helal A, Rizk MS, Esaily HA. Serum Krebs von den Lungen-6 and lung ultrasound B lines as potential diagnostic and prognostic factors for rheumatoid arthritis-associated interstitial lung disease. Clin Rheumatol. 2021;40(7):2689-2697. doi: 10.1007/s10067-021-05585-y</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Doğan C, Kıral N, Parmaksız ET, Çağlayan B, Sağmen SB, Salepçi B, et al. Ultrasonographic evaluation of lung parenchyma involvement in sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis. 2019;36(2):130-140. doi: 10.36141/svdld.v36i2.7312</mixed-citation><mixed-citation xml:lang="en">Doğan C, Kıral N, Parmaksız ET, Çağlayan B, Sağmen SB, Salepçi B, et al. Ultrasonographic evaluation of lung parenchyma involvement in sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis. 2019;36(2):130-140. doi: 10.36141/svdld.v36i2.7312</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Moazedi-Fuerst FC, Zechner PM, Tripolt NJ, Kielhauser SM, Brickmann K, Scheidl S, et al. Pulmonary echography in systemic sclerosis. Clin Rheumatol. 2012;31(11):1621-1625. doi: 10.1007/s10067-012-2055-8</mixed-citation><mixed-citation xml:lang="en">Moazedi-Fuerst FC, Zechner PM, Tripolt NJ, Kielhauser SM, Brickmann K, Scheidl S, et al. Pulmonary echography in systemic sclerosis. Clin Rheumatol. 2012;31(11):1621-1625. doi: 10.1007/s10067-012-2055-8</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Mohammadi A, Oshnoei S, Ghasemi-rad M. Comparison of a new, modified lung ultrasonography technique with high resolution CT in the diagnosis of the alveolo-interstitial syndrome of systemic scleroderma. Med Ultrason. 2014;16:27-31. doi: 10.11152/mu.2014.2066.161.am1so2</mixed-citation><mixed-citation xml:lang="en">Mohammadi A, Oshnoei S, Ghasemi-rad M. Comparison of a new, modified lung ultrasonography technique with high resolution CT in the diagnosis of the alveolo-interstitial syndrome of systemic scleroderma. Med Ultrason. 2014;16:27-31. doi: 10.11152/mu.2014.2066.161.am1so2</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Ахунова РР, Ахунова ГР. Ультразвуковое исследование легких: возможности диагностики интерстициального заболевания легких, ассоциированного с ревматоидным артритом. Научно-практическая ревматология. 2023;61(1):129-137.</mixed-citation><mixed-citation xml:lang="en">Ahunova RR, Ahunova GR. Pulmonary ultrasound: Diagnostic possibilities for interstitial lung disease associated with rheumatoid arthritis. Nauchno-Prakticheskaya Revmatologia = Rheumatology Science and Practice. 2023;61(1):129-137 (In Russ.). doi: 10.47360/1995-4484-2023-129-137</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Gargani L, Volpicelli G. How do it: Lung ultrasound. Cardiovasc Ultrasound. 2014;12:25. doi: 10.1186/1476-7120-12-25</mixed-citation><mixed-citation xml:lang="en">Gargani L, Volpicelli G. How do it: Lung ultrasound. Cardiovasc Ultrasound. 2014;12:25. doi: 10.1186/1476-7120-12-25</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Reyes-Long S, Gutierrez M, Clavijo-Cornejo D, Alfaro-Rodríguez A, González-Sámano K, Cortes-Altamirano JL, et al. Subclinical interstitial lung disease in patients with systemic sclerosis. A pilot study on the role of ultrasound. Reumatol Clin (Engl Ed). 2021;17(3):144-149. doi: 10.1016/j.reuma.2019.05.004</mixed-citation><mixed-citation xml:lang="en">Reyes-Long S, Gutierrez M, Clavijo-Cornejo D, Alfaro-Rodríguez A, González-Sámano K, Cortes-Altamirano JL, et al. Subclinical interstitial lung disease in patients with systemic sclerosis. A pilot study on the role of ultrasound. Reumatol Clin (Engl Ed). 2021;17(3):144-149. doi: 10.1016/j.reuma.2019.05.004</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Reissig A, Kroegel C. Transthoracic sonography of diffuse parenchymal lung disease: The role of comet tail artifacts. J Ultrasond Med. 2003;22:173-180.</mixed-citation><mixed-citation xml:lang="en">Reissig A, Kroegel C. Transthoracic sonography of diffuse parenchymal lung disease: The role of comet tail artifacts. J Ultrasond Med. 2003;22:173-180.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Vizioli L, Ciccarese F, Forti P, Chiesa AM, Giovagnoli M, Mughetti M, et al. Integrated use of lung ultrasound and chest X-ray in the detection of interstitial lung disease. Respiration. 2017;93(1):15-22. doi: 10.1159/000452225</mixed-citation><mixed-citation xml:lang="en">Vizioli L, Ciccarese F, Forti P, Chiesa AM, Giovagnoli M, Mughetti M, et al. Integrated use of lung ultrasound and chest X-ray in the detection of interstitial lung disease. Respiration. 2017;93(1):15-22. doi: 10.1159/000452225</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Кармазановский ГГ, Нуднов НВ, Юдин АЛ, Петриков СС. COVID-19: лучевая диагностика и мониторинг лечения. М.: Крафт+; 2020.</mixed-citation><mixed-citation xml:lang="en">Karmazanovskiy GG, Nudnov NV, Yudin AL, Petrikov SS. COVID-19: X-ray diagnostics and treatment monitoring. Moscow: Kraft+; 2020 (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Петров АА, Сафарова АФ, Рачина СА, Кабалова ЖБ, Сафарова НБ, Тесаков ИП, и др. Ультразвуковое исследование легких: методика выполнения и перспективы в диагностике нозокомиальной пневмонии. Практическая пульмонология. 2018;3:38-45.</mixed-citation><mixed-citation xml:lang="en">Petrov AA, Safarova AF, Rachina ZA, Kabalova ZhB, Safarova NB, Tesakov IP, et al. Ultrasound examination of lungs: Procedure and role in diagnosis of nosocomial pneumonia. Practical Pulmonology. 2018;3:38-45 (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Picano E, Frassi F, Agricola E, Gligorova S, Gargani L, Mottola G. Ultrasound lung comets: A clinically useful sign of extravascular lung water. J Am Soc Echocardiogr. 2006;19(3):356-363. doi: 10.1016/j.echo.2005.05.019</mixed-citation><mixed-citation xml:lang="en">Picano E, Frassi F, Agricola E, Gligorova S, Gargani L, Mottola G. Ultrasound lung comets: A clinically useful sign of extravascular lung water. J Am Soc Echocardiogr. 2006;19(3):356-363. doi: 10.1016/j.echo.2005.05.019</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Doveri M, Frassi F, Consensi A, Vesprini E, Gargani L, Tafuri M, et al. Le comete ultrasoniche polmonari (ULC): Un nuovo segno ecografico di fibrosi polmonare nella sclerodermia [Ultrasound lung comets: New echographic sign of lung interstitial fibrosis in systemic sclerosis. Reumatismo. 2008;60(3):180-184 (In Italian). doi: 10.4081/reumatismo.2008.180</mixed-citation><mixed-citation xml:lang="en">Doveri M, Frassi F, Consensi A, Vesprini E, Gargani L, Tafuri M, et al. Le comete ultrasoniche polmonari (ULC): Un nuovo segno ecografico di fibrosi polmonare nella sclerodermia [Ultrasound lung comets: New echographic sign of lung interstitial fibrosis in systemic sclerosis. Reumatismo. 2008;60(3):180-184 (In Italian). doi: 10.4081/reumatismo.2008.180</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Gargani L, Doveri M, D’Errico L, Frassi F, Bazzichi ML, Delle Sedie A, et al. Ultrasound lung comets in systemic sclerosis: A chest sonography hallmark of pulmonary interstitial fibrosis. Rheumatology (Oxford). 2009;48(11):1382-1387. doi: 10.1093/rheumatology/kep263</mixed-citation><mixed-citation xml:lang="en">Gargani L, Doveri M, D’Errico L, Frassi F, Bazzichi ML, Delle Sedie A, et al. Ultrasound lung comets in systemic sclerosis: A chest sonography hallmark of pulmonary interstitial fibrosis. Rheumatology (Oxford). 2009;48(11):1382-1387. doi: 10.1093/rheumatology/kep263</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Gigante A, Rossi Fanelli F, Lucci S, Barilaro G, Quarta S, Barbano B, et al. Lung ultrasound in systemic sclerosis: Correlation with high-resolution computed tomography, pulmonary function tests and clinical variables of disease. Intern Emerg Med. 2016;11(2):213-217. doi: 10.1007/s11739-015-1329-y</mixed-citation><mixed-citation xml:lang="en">Gigante A, Rossi Fanelli F, Lucci S, Barilaro G, Quarta S, Barbano B, et al. Lung ultrasound in systemic sclerosis: Correlation with high-resolution computed tomography, pulmonary function tests and clinical variables of disease. Intern Emerg Med. 2016;11(2):213-217. doi: 10.1007/s11739-015-1329-y</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Çakir Edis E, Hatipoğlu ON, Pamuk ÖN, Mutlucan Eraslan R, Aktöz M, Tuncel SA. Effectiveness of thoracic ultrasonography in the evaluation of the severity of pulmonary involvement in patients with systemic sclerosis. Arch Rheumatol. 2016;31(4):364-370. doi: 10.5606/ArchRheumatol.2016.5849</mixed-citation><mixed-citation xml:lang="en">Çakir Edis E, Hatipoğlu ON, Pamuk ÖN, Mutlucan Eraslan R, Aktöz M, Tuncel SA. Effectiveness of thoracic ultrasonography in the evaluation of the severity of pulmonary involvement in patients with systemic sclerosis. Arch Rheumatol. 2016;31(4):364-370. doi: 10.5606/ArchRheumatol.2016.5849</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Tardella M, Di Carlo M, Carotti M, Filippucci E, Grassi W, Salaffi F. Ultrasound B-lines in the evaluation of interstitial lung disease in patients with systemic sclerosis: Cut-off point definition for the presence of significant pulmonary fibrosis. Medicine (Baltimore). 2018;97(18):e0566. doi: 10.1097/MD.0000000000010566</mixed-citation><mixed-citation xml:lang="en">Tardella M, Di Carlo M, Carotti M, Filippucci E, Grassi W, Salaffi F. Ultrasound B-lines in the evaluation of interstitial lung disease in patients with systemic sclerosis: Cut-off point definition for the presence of significant pulmonary fibrosis. Medicine (Baltimore). 2018;97(18):e0566. doi: 10.1097/MD.0000000000010566</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Gutierrez M, Salaffi F, Carotti M, Tardella M, Pineda C, Bertolazzi C, et al. Utility of a simplified ultrasound assessment to assess interstitial pulmonary fibrosis in connective tissue disorders – Preliminary results. Arthritis Res Ther. 2011;13(4):R134. doi: 10.1186/ar3446</mixed-citation><mixed-citation xml:lang="en">Gutierrez M, Salaffi F, Carotti M, Tardella M, Pineda C, Bertolazzi C, et al. Utility of a simplified ultrasound assessment to assess interstitial pulmonary fibrosis in connective tissue disorders – Preliminary results. Arthritis Res Ther. 2011;13(4):R134. doi: 10.1186/ar3446</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Hassan RI, Lubertino LI, Barth MA, Quaglia MF, Montoya SF, Kerzberg E, et al. Lung Ultrasound as a screening method for interstitial lung disease in patients with systemic sclerosis. J Clin Rheumatol. 2019;25(7):304-307. doi: 10.1097/RHU.0000000000000860</mixed-citation><mixed-citation xml:lang="en">Hassan RI, Lubertino LI, Barth MA, Quaglia MF, Montoya SF, Kerzberg E, et al. Lung Ultrasound as a screening method for interstitial lung disease in patients with systemic sclerosis. J Clin Rheumatol. 2019;25(7):304-307. doi: 10.1097/RHU.0000000000000860</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Fairchild R, Chung M, Yang D, Sharpless L, Li S, Chung L. Development and assessment of novel lung ultrasound interpretation criteria for the detection of interstitial lung disease in systemic sclerosis. Arthritis Care Res (Hoboken). 2021;73(9):1338-1342. doi: 10.1002/acr.24338</mixed-citation><mixed-citation xml:lang="en">Fairchild R, Chung M, Yang D, Sharpless L, Li S, Chung L. Development and assessment of novel lung ultrasound interpretation criteria for the detection of interstitial lung disease in systemic sclerosis. Arthritis Care Res (Hoboken). 2021;73(9):1338-1342. doi: 10.1002/acr.24338</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Delle Sedie A, Doveri M, Frassi F, Gargani L, D’Errico G, Pepe P, et al. Ultrasound lung comets in systemic sclerosis: A useful tool to detect lung interstitial fibrosis. Clin Exp Rheumatol. 2010;28(5 Suppl 62):S54.</mixed-citation><mixed-citation xml:lang="en">Delle Sedie A, Doveri M, Frassi F, Gargani L, D’Errico G, Pepe P, et al. Ultrasound lung comets in systemic sclerosis: A useful tool to detect lung interstitial fibrosis. Clin Exp Rheumatol. 2010;28(5 Suppl 62):S54.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Gargani L, Bruni C, Romei C, Frumento P, Moreo A, Agoston G, et al. Prognostic value of lung ultrasound B-lines in systemic sclerosis. Chest. 2020;158(4):1515-1525. doi: 10.1016/j.chest.2020.03.075</mixed-citation><mixed-citation xml:lang="en">Gargani L, Bruni C, Romei C, Frumento P, Moreo A, Agoston G, et al. Prognostic value of lung ultrasound B-lines in systemic sclerosis. Chest. 2020;158(4):1515-1525. doi: 10.1016/j.chest.2020.03.075</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Vasco PG, de Luna Cardenal G, Garrido IM, Pinilla JM, Rodríguez GF, Mateo JJ, et al. Assessment of interstitial lung disease in Sjögren’s syndrome by lung ultrasound: A pilot study of correlation with high-resolution chest tomography. Intern Emerg Med. 2017;12(3):327-331. doi: 10.1007/s11739-016-1582-8</mixed-citation><mixed-citation xml:lang="en">Vasco PG, de Luna Cardenal G, Garrido IM, Pinilla JM, Rodríguez GF, Mateo JJ, et al. Assessment of interstitial lung disease in Sjögren’s syndrome by lung ultrasound: A pilot study of correlation with high-resolution chest tomography. Intern Emerg Med. 2017;12(3):327-331. doi: 10.1007/s11739-016-1582-8</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Gasperini ML, Gigante A, Iacolare A, Pellicano C, Lucci S, Rosato E. The predictive role of lung ultrasound in progression of scleroderma interstitial lung disease. Clin Rheumatol. 2020;39(1):119-123. doi: 10.1007/s10067-019-04686-z</mixed-citation><mixed-citation xml:lang="en">Gasperini ML, Gigante A, Iacolare A, Pellicano C, Lucci S, Rosato E. The predictive role of lung ultrasound in progression of scleroderma interstitial lung disease. Clin Rheumatol. 2020;39(1):119-123. doi: 10.1007/s10067-019-04686-z</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Pinal-Fernández I, Pallisa Núñez E, Selva-O’Callaghan A, Castella-Fierro E, Martínez-Gómez X, Vilardell-Tarrés M. Correlation of ultrasound B-lines with high-resolution computed tomography in antisynthetase syndrome. Clin Exp Rheumatol. 2014;32(3):404-407.</mixed-citation><mixed-citation xml:lang="en">Pinal-Fernández I, Pallisa Núñez E, Selva-O’Callaghan A, Castella-Fierro E, Martínez-Gómez X, Vilardell-Tarrés M. Correlation of ultrasound B-lines with high-resolution computed tomography in antisynthetase syndrome. Clin Exp Rheumatol. 2014;32(3):404-407.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Pinal-Fernandez I, Pallisa-Nuñez E, Selva-O’Callaghan A, Castella-Fierro E, Simeon-Aznar CP, Fonollosa-Pla V, et al. Pleural irregularity, a new ultrasound sign for the study of interstitial lung disease in systemic sclerosis and antisynthetase syndrome. Clin Exp Rheumatol. 2015;33(4 Suppl 91):S136-S141.</mixed-citation><mixed-citation xml:lang="en">Pinal-Fernandez I, Pallisa-Nuñez E, Selva-O’Callaghan A, Castella-Fierro E, Simeon-Aznar CP, Fonollosa-Pla V, et al. Pleural irregularity, a new ultrasound sign for the study of interstitial lung disease in systemic sclerosis and antisynthetase syndrome. Clin Exp Rheumatol. 2015;33(4 Suppl 91):S136-S141.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Wang Y, Chen S, Lin J, Xie X, Hu S, Lin Q, et al. Lung ultrasound B-lines and serum KL-6 correlate with the severity of idiopathic inflammatory myositis-associated interstitial lung disease. Rheumatology (Oxford). 2020;59(8):2024-2029. doi: 10.1093/rheumatology/kez571</mixed-citation><mixed-citation xml:lang="en">Wang Y, Chen S, Lin J, Xie X, Hu S, Lin Q, et al. Lung ultrasound B-lines and serum KL-6 correlate with the severity of idiopathic inflammatory myositis-associated interstitial lung disease. Rheumatology (Oxford). 2020;59(8):2024-2029. doi: 10.1093/rheumatology/kez571</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Buda N, Masiak A, Zdrojewski Z. Utility of lung ultrasound in ANCA-associated vasculitis with lung involvement. PLoS One. 2019;14(9):e0222189. doi: 10.1371/journal.pone.0222189</mixed-citation><mixed-citation xml:lang="en">Buda N, Masiak A, Zdrojewski Z. Utility of lung ultrasound in ANCA-associated vasculitis with lung involvement. PLoS One. 2019;14(9):e0222189. doi: 10.1371/journal.pone.0222189</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Aghdashi M, Broofeh B, Mohammadi A. Diagnostic performances of high resolution trans-thoracic lung ultrasonography in pulmonary alveoli-interstitial involvement of rheumatoid lung disease. Int J Clin Exp Med. 2013;6:562-566.</mixed-citation><mixed-citation xml:lang="en">Aghdashi M, Broofeh B, Mohammadi A. Diagnostic performances of high resolution trans-thoracic lung ultrasonography in pulmonary alveoli-interstitial involvement of rheumatoid lung disease. Int J Clin Exp Med. 2013;6:562-566.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Tardella M, Gutierrez M, Salaffi F, Carotti M, Ariani A, Bertolazzi C, et al. Ultrasound in the assessment of pulmonary fibrosis in connective tissue disorders: Correlation with high-resolution computed tomography. J Rheumatol. 2012;39(8):1641-1647. doi: 10.3899/jrheum.120104</mixed-citation><mixed-citation xml:lang="en">Tardella M, Gutierrez M, Salaffi F, Carotti M, Ariani A, Bertolazzi C, et al. Ultrasound in the assessment of pulmonary fibrosis in connective tissue disorders: Correlation with high-resolution computed tomography. J Rheumatol. 2012;39(8):1641-1647. doi: 10.3899/jrheum.120104</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Moazedi-Fuerst FC, Kielhauser S, Brickmann K, Tripolt N, Meilinger M, Lufti A, et al. Sonographic assessment of interstitial lung disease in patients with rheumatoid arthritis, systemic sclerosis and systemic lupus erythematosus. Clin Exp Rheumatol. 2015;33(4 Suppl 91):S87-S91.</mixed-citation><mixed-citation xml:lang="en">Moazedi-Fuerst FC, Kielhauser S, Brickmann K, Tripolt N, Meilinger M, Lufti A, et al. Sonographic assessment of interstitial lung disease in patients with rheumatoid arthritis, systemic sclerosis and systemic lupus erythematosus. Clin Exp Rheumatol. 2015;33(4 Suppl 91):S87-S91.</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Buda N, Piskunowicz M, Porzezińska M, Kosiak W, Zdrojewski Z. Lung ultrasonography in the evaluation of interstitial lung disease in systemic connective tissue diseases: Criteria and severity of pulmonary fibrosis – Analysis of 52 patients. Ultraschall Med. 2016;37:379-385. doi: 10.1055/s-0041-110590</mixed-citation><mixed-citation xml:lang="en">Buda N, Piskunowicz M, Porzezińska M, Kosiak W, Zdrojewski Z. Lung ultrasonography in the evaluation of interstitial lung disease in systemic connective tissue diseases: Criteria and severity of pulmonary fibrosis – Analysis of 52 patients. Ultraschall Med. 2016;37:379-385. doi: 10.1055/s-0041-110590</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Fehr A, Baghdady S, Ghaleb R, Maklad S. Transthoracic ultrasound in the detection of interstitial pulmonary fibrosis in patients with rheumatic connective tissue diseases. Bull Hosp Jt Dis. 2018;76:156-160.</mixed-citation><mixed-citation xml:lang="en">Fehr A, Baghdady S, Ghaleb R, Maklad S. Transthoracic ultrasound in the detection of interstitial pulmonary fibrosis in patients with rheumatic connective tissue diseases. Bull Hosp Jt Dis. 2018;76:156-160.</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Vicente-Rabaneda EF, Acebes C, Castañeda S. Usefulness of extra-articular ultrasound applied to systemic inflammatory diseases in clinical practice. Reumatol Clin. 2021;17(4):229-236. doi: 10.1016/j.reuma.2020.04.005</mixed-citation><mixed-citation xml:lang="en">Vicente-Rabaneda EF, Acebes C, Castañeda S. Usefulness of extra-articular ultrasound applied to systemic inflammatory diseases in clinical practice. Reumatol Clin. 2021;17(4):229-236. doi: 10.1016/j.reuma.2020.04.005</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Cappelli S, Bellando Randone S, Camiciottoli G, De Paulis A, Guiducci S, Matucci-Cerinic M. Interstitial lung disease in systemic sclerosis: Where do we stand? Eur Respir Rev. 2015;24(137):411-419. doi: 10.1183/16000617.00002915</mixed-citation><mixed-citation xml:lang="en">Cappelli S, Bellando Randone S, Camiciottoli G, De Paulis A, Guiducci S, Matucci-Cerinic M. Interstitial lung disease in systemic sclerosis: Where do we stand? Eur Respir Rev. 2015;24(137):411-419. doi: 10.1183/16000617.00002915</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
