rspНаучно-практическая ревматологияRheumatology Science and Practice1995-44841995-4492IMA-PRESS, LLC10.47360/1995-4484-2024-598-605rsp-3655Research ArticleОБЗОРЫ И ЛЕКЦИИREVIEWS AND LECTURESВлияние курения табака и отказа от него на риск развития и течение ревматоидного артритаThe impact of cigarette smoking and smoking cessation on risk and phenotype of rheumatoid arthritishttps://orcid.org/0000-0002-4579-2836ЗоткинЕ. Г.ZotkinE. G.

Зоткин Евгений Германович 

115522, Москва, Каширское шоссе, 34а

Evgeniy G. Zotkin 

115522, Moscow, Kashirskoye Highway, 34A

 

ezotkin@mail.ruhttps://orcid.org/0000-0001-7063-1834ПожидаевЕ. В.PozhidaevE. V.

115522, Москва, Каширское шоссе, 34а

Egor V. Pozhidaev 

115522, Moscow, Kashirskoye Highway, 34A

 

https://orcid.org/0000-0001-9820-8851ГордеевА. В.GordeevA. V.

115522, Москва, Каширское шоссе, 34а

Andrey V. Gordeev 

115522, Moscow, Kashirskoye Highway, 34A

 

ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»РоссияV.A. Nasonova Research Institute of RheumatologyRussian Federation202426122024626598605Copyright © Зоткин Е.Г., Пожидаев Е.В., Гордеев А.В., 20242024Зоткин Е.Г., Пожидаев Е.В., Гордеев А.В.Zotkin E.G., Pozhidaev E.V., Gordeev A.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://rsp.mediar-press.net/rsp/article/view/3655

Представлен литературный обзор, в котором проведена оценка результатов научных исследований за предыдущие 10 лет, направленных на изучение влияния курения табака на риск развития ревматоидного артрита (РА). Рассмотрены основные механизмы взаимодействия системы главного комплекса гистосовместимости, синтеза РА-специфических антител, других иммунных нарушений под влиянием сигаретного дыма у больных с РА. Обобщены данные, свидетельствующие о положительном влиянии отказа от курения на течение РА.

Literature review presents the data of recent scientific studies aimed to analyze the impact of cigarette smoking on the risk of rheumatoid arthritis (RA). It is shown the main mechanisms of interaction between genetic constitution, synthesis of RA-specific antibodies, and other immune trait under the influence of cigarette smoke in patients with RA. We presented summarized data indicating the positive effect of smoking cessation in RA patients.

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The authors declare that there are no conflicts of interest present.