rspНаучно-практическая ревматологияRheumatology Science and Practice1995-44841995-4492IMA-PRESS, LLC10.47360/1995-4484-2025-24-36rsp-3701Research ArticleПРОГРЕСС В РЕВМАТОЛОГИИ В XXI ВЕКЕPROGRESS IN RHEUMATOLOGY IN THE XXI CENTURYРадиомика — фронтир современной ревматологии: достижения и перспективы визуализации поражения органов грудной клеткиRadiomics as a new frontier in modern rheumatology: Chest pathology visualization advances and prospectshttps://orcid.org/0000-0003-2641-9785БекетоваТ. В.BeketovaT. V.

Бекетова Татьяна Валентиновна.

121356, Москва, ул. Маршала Тимошенко, 15; 115522, Москва, Каширское шоссе, 34а; 107023, Москва, ул. Большая Семеновская, 38

Tatiana V. Beketova.

121359, Moscow, Marshala Timoshenko str., 19, building 1A; 115522, Moscow, Kashirskoye Highway, 34A; 107023, Moscow, Bolshaya Semyonovskaya str., 38

doc@tvbek.ruhttps://orcid.org/0000-0002-1598-8360НасоновЕ. Л.NasonovE. L.

115522, Москва, Каширское шоссе, 34а

Evgeny L. Nasonov.

115522, Moscow, Kashirskoye Highway, 34A

https://orcid.org/0009-0004-5892-2902АлексеевМ. А.AlekseevM. A.

107023, Москва, ул. Большая Семеновская, 38

Mikhail A. Alekseev.

107023, Moscow, Bolshaya Semyonovskaya str., 38

https://orcid.org/0000-0002-9146-0904ЩепихинЕ. И.ShchepikhinE. I.

121356, Москва, ул. Маршала Тимошенко, 15

Evgeniy I. Shchepikhin.

121359, Moscow, Marshala Timoshenko str., 19, building 1A

https://orcid.org/0000-0001-9419-2282ФилипповичЮ. Н.PhilippovichYu. N.

107023, Москва, ул. Большая Семеновская, 38

Yuriy N. Philippovich.

107023, Moscow, Bolshaya Semyonovskaya str., 38

https://orcid.org/0000-0003-0004-2334КружаловА. С.KruzhalovA. S.

107023, Москва, ул. Большая Семеновская, 38

Alexey S. Kruzhalov.

107023, Moscow, Bolshaya Semyonovskaya str., 38

https://orcid.org/0000-0002-8291-2411ФилипповичА. Ю.PhilippovichA. Yu.

107023, Москва, ул. Большая Семеновская, 38

Andrey Yu. Philippovich.

107023, Moscow, Bolshaya Semyonovskaya str., 38

https://orcid.org/0000-0001-6743-4012КульбакВ. А.KulbakV. A.

117997, Москва, ул. Большая Серпуховская, 27; 119991, Москва, Ломоносовский просп., 27, корп. 1

Vladimir A. Kulbak.

117997, Moscow, Bolshaya Serpukhovskaya str., 27; 119991, Moscow, Leninskie Gory, 12

https://orcid.org/0009-0002-6219-2370АргуноваД. А.ArgunovaD. A.

117997, Москва, ул. Большая Серпуховская, 27

Daria A. Argunova.

117997, Moscow, Bolshaya Serpukhovskaya str., 27

https://orcid.org/0000-0002-6872-5310ШахновичП. Г.ShakhnovichP. G.

121356, Москва, ул. Маршала Тимошенко, 15

Pavel G. Shakhnovich.

117997, Moscow, Bolshaya Serpukhovskaya str., 27

https://orcid.org/0009-0003-2750-2764ПраздничныхТ. А.PrazdnichnykhT. A.

119991, Москва, Ломоносовский просп., 27, корп. 1

Trofim A. Prazdnichnykh.

119991, Moscow, Leninskie Gory, 12

https://orcid.org/0009-0006-7076-6169ОбидинМ. П.ObidinM. P.

119991, Москва, Ломоносовский просп., 27, корп. 1

Mikhail P. Obidin.

119991, Moscow, Leninskie Gory, 12

https://orcid.org/0000-0001-6175-1076КрасноваТ. Н.KrasnovaT. N.

119991, Москва, Ломоносовский просп., 27, корп. 1

Tatiana N. Krasnova.

119991, Moscow, Leninskie Gory, 12

https://orcid.org/0000-0002-8929-3748ВладимироваН. Н.VladimirovaN. N.

121356, Москва, ул. Маршала Тимошенко, 15

Nadezhda N. Vladimirova.

121359, Moscow, Marshala Timoshenko str., 19, building 1A

ФГБУ «Центральная клиническая больница с поликлиникой» Управления делами Президента Российской Федерации; ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»; ФГАОУ ВО «Московский политехнический университет»РоссияCentral State Medical Academy of the Administrative Directorate of the President of the Russian Federation; V.A. Nasonova Research Institute of Rheumatology; Moscow Polytechnic UniversityRussian FederationФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»РоссияV.A. Nasonova Research Institute of RheumatologyRussian FederationФГАОУ ВО «Московский политехнический университет»РоссияMoscow Polytechnic UniversityRussian FederationФГБУ «Центральная клиническая больница с поликлиникой» Управления делами Президента Российской ФедерацииРоссияCentral State Medical Academy of the Administrative Directorate of the President of the Russian FederationRussian FederationФГБУ «Национальный медицинский исследовательский центр хирургии им. А.В. Вишневского» Минздрава России; ФГБОУ ВО «Московский государственный университет имени М.В. Ломоносова»РоссияA.V. Vishnevsky National Medical Research Center of Surgery; Lomonosov Moscow State UniversityRussian FederationФГБУ «Национальный медицинский исследовательский центр хирургии им. А.В. Вишневского» Минздрава РоссииРоссияA.V. Vishnevsky National Medical Research Center of SurgeryRussian FederationФГБОУ ВО «Московский государственный университет имени М.В. Ломоносова»РоссияLomonosov Moscow State UniversityRussian Federation2025020320256312436Copyright © Бекетова Т.В., Насонов Е.Л., Алексеев М.А., Щепихин Е.И., Филиппович Ю.Н., Кружалов А.С., Филиппович А.Ю., Кульбак В.А., Аргунова Д.А., Шахнович П.Г., Праздничных Т.А., Обидин М.П., Краснова Т.Н., Владимирова Н.Н., 20252025Бекетова Т.В., Насонов Е.Л., Алексеев М.А., Щепихин Е.И., Филиппович Ю.Н., Кружалов А.С., Филиппович А.Ю., Кульбак В.А., Аргунова Д.А., Шахнович П.Г., Праздничных Т.А., Обидин М.П., Краснова Т.Н., Владимирова Н.Н.Beketova T.V., Nasonov E.L., Alekseev M.A., Shchepikhin E.I., Philippovich Y.N., Kruzhalov A.S., Philippovich A.Y., Kulbak V.A., Argunova D.A., Shakhnovich P.G., Prazdnichnykh T.A., Obidin M.P., Krasnova T.N., Vladimirova N.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://rsp.mediar-press.net/rsp/article/view/3701

На примере ревматологии в статье рассмотрены современные тенденции развития цифровых технологий в медицине; обсуждается значение радиомики, совмещающей радиологию, математическое моделирование и глубокое машинное обучение. Текстурный анализ изображений компьютерной томографии и других методов визуализации более глубоко характеризует патофизиологические особенности тканей и может рассматриваться как неинвазивная «виртуальная биопсия». Показано, что радиомика увеличивает качество диагностического и предсказательного моделирования. Обсуждается потенциал применения радиомических моделей для изучения и прогнозирования поражения органов грудной клетки при различных патологических состояниях, включая иммуновоспалительные ревматические заболевания (РЗ). Прогресс в диагностике и лечении РЗ может быть обеспечен интеграцией радиомики и омиксных технологий. Цифровая эра, открывающая широкие перспективы для прогресса в ревматологии, несомненно, потребует комплексного решения новых проблем, технических, юридических и этических.

The article discusses the modern trends in the development of digital technologies in medicine, exemplified by rheumatology, especially, the significance of radiomics, which combines radiology, mathematical modeling, and deep machine learning. Texture analysis of computed tomography images and other imaging methods provides a more deeply characterization of the pathophysiological features of tissues and can be considered as a non-invasive “virtual biopsy”.

It is shown that radiomics enhances the quality of diagnostic and predictive modeling. The potential application of radiomic models for studying and predicting chest organ lesions in various pathological conditions, including immune mediated inflammatory diseases, systemic vasculitis.

Progress in the diagnosis and treatment of rheumatic diseases may be facilitated by the integration of radiomics and other omics technologies. The digital era, which opens up vast prospects for advancements in rheumatology, will undoubtedly require complex solutions to new technical, legal, and ethical challenges.

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The authors declare that there are no conflicts of interest present.