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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rsp</journal-id><journal-title-group><journal-title xml:lang="ru">Научно-практическая ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Rheumatology Science and Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-4484</issn><issn pub-type="epub">1995-4492</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.47360/1995-4484-2025-443-451</article-id><article-id custom-type="elpub" pub-id-type="custom">rsp-3804</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS AND LECTURES</subject></subj-group></article-categories><title-group><article-title>Болезнь Шёгрена: мифы и реальность. Часть II</article-title><trans-title-group xml:lang="en"><trans-title>Sjogren’s disease: myths and reality. Part II</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4188-3578</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чальцев</surname><given-names>Б. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Chaltsev</surname><given-names>B. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Чальцев Богдан Дмитриевич </p><p>115522, Москва, Каширское шоссе, 34а</p></bio><bio xml:lang="en"><p>Bogdan D. Chaltsev </p><p>115522, Moscow, Kashirskoye Highway, 34A</p></bio><email xlink:type="simple">bodya92@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1425-8622</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Васильев</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Vasilyev</surname><given-names>V. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>107140, Москва, ул. Нижняя Красносельская, 4</p></bio><bio xml:lang="en"><p>Vladimir I. Vasilyev </p><p>107140, Moscow, Nizhnyaya Krasnoselskaya str., 4</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8099-2107</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Торгашина</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Torgashina</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>115522, Москва, Каширское шоссе, 34а</p></bio><bio xml:lang="en"><p>Anna V. Torgashina </p><p>115522, Moscow, Kashirskoye Highway, 34A</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.A. Nasonova Research Institute of Rheumatology</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ООО «Ревмоцентр»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>“Revmotsentr” LLC</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>01</day><month>11</month><year>2025</year></pub-date><volume>63</volume><issue>5</issue><fpage>443</fpage><lpage>451</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Чальцев Б.Д., Васильев В.И., Торгашина А.В., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Чальцев Б.Д., Васильев В.И., Торгашина А.В.</copyright-holder><copyright-holder xml:lang="en">Chaltsev B.D., Vasilyev V.I., Torgashina A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://rsp.mediar-press.net/rsp/article/view/3804">https://rsp.mediar-press.net/rsp/article/view/3804</self-uri><abstract><p>Стоматологические и офтальмологические проявления болезни Шёгрена (БШ) впервые описаны более 100 лет назад, а в качестве самостоятельной нозологической единицы БШ получила признание в 1965 году. Тем не менее в настоящее время диагностика и лечение данного заболевания по-прежнему вызывают существенные затруднения. Во второй части статьи приведены наиболее распространенные и значимые мифы о клинических и лабораторных проявлениях, лимфопролиферативных осложнениях, а также о лечении БШ.</p></abstract><trans-abstract xml:lang="en"><p>Oral and ocular manifestations of Sjögren’s disease (SjD) were first described over 100 years ago, but SjD was recognized as an independent nosology in 1965. However, currently the diagnosis and treatment of this disease still pose significant difficulties. The second part of the article presents the most common and significant myths in clinical and laboratory manifestations, lymphoproliferative complications, and treatment of SjD.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>болезнь Шёгрена</kwd><kwd>синдром Шёгрена</kwd><kwd>MALT-лимфома</kwd><kwd>криоглобулинемия</kwd><kwd>васкулит</kwd><kwd>ритуксимаб</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Sjogren’s disease</kwd><kwd>Sjogren’s syndrome</kwd><kwd>MALT lymphoma</kwd><kwd>cryoglobulinemia</kwd><kwd>vasculitis</kwd><kwd>rituximab</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Статья подготовлена в рамках фундаментальной темы, регистрационный № 1021051402790-6.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Vivino FB, Bunya VY, Massaro-Giordano G, Johr CR, Giattino SL, Schorpion A, et al. 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