rspНаучно-практическая ревматологияRheumatology Science and Practice1995-44841995-4492IMA-PRESS, LLC10.47360/1995-4484-2026-99-103rsp-3880Research ArticleОПИСАНИЕ СЛУЧАЯCASE DESCRIPTIONЭозинофильный гранулематоз с полиангиитом, ассоциированный с вирусом гепатита B: сложности диагностики и терапии (описание клинического случая)Eosinophilic granulomatosis with polyangiitis associated with hepatitis B virus: Diagnostic and therapeutic challenges (a clinical case report)https://orcid.org/0009-0009-9261-5961БабаеваЛ. К.BabayevaL. K.

Бабаева Леман Камаладдин

AZ0100, Хырдалан, ул. Галубийе, 12

Leman K. Babayeva 

AZ0100,  Khyrdalan, Galubiye str, 12

leman.babayeva.1987@gmail.comhttps://orcid.org/0000-0002-6393-3807КасумовaФ. Н.GasimovaF. N.

AZ1012, Баку, ул. Музаффара Гасанова, 35

AZ1012, Baku, Muzaffara Hasanova str., 35

https://orcid.org/0009-0000-2038-1291БахышоваА. Н.BakhishovaA. N.

AZ0100, Хырдалан, ул. Галубийе, 12

AZ0100,  Khyrdalan, Galubiye str, 12

https://orcid.org/0009-0003-8439-3672ГулиеваИ. М.GuliyevaI. M.

AZ1025,  Баку, ул. Юсифа Сафарова, 17а

AZ1025, Baku, Yusifa Safarova str., 17A

https://orcid.org/0000-0002-5805-3741БабаеваГ. Г.BabayevaG. H.

AZ1012, Баку, ул. Музаффара Гасанова, 35

AZ1012, Baku, Muzaffara Hasanova str., 35

Центральная больница Абшеронского районаАзербайджанAbsheron Central District HospitalAzerbaijanАзербайджанский государственный институт усовершенствования врачей им. А. АлиеваАзербайджанAzerbaijan State Advanced Training Institute for Doctors named after A. AliyevAzerbaijanЦентральная больница нефтяниковАзербайджанCentral Hospital for OilworkersAzerbaijan20260203202664199103Copyright © Бабаева Л.К., Касумовa Ф.Н., Бахышова А.Н., Гулиева И.М., Бабаева Г.Г., 20262026Бабаева Л.К., Касумовa Ф.Н., Бахышова А.Н., Гулиева И.М., Бабаева Г.Г.Babayeva L.K., Gasimova F.N., Bakhishova A.N., Guliyeva I.M., Babayeva G.H.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://rsp.mediar-press.net/rsp/article/view/3880

В представленной статье рассматривается редкий клинический случай эозинофильного гранулематоза с полиангиитом у 63-летнего пациента с полинейропатией, выраженной потерей массы тела и васкулитной сыпью на нижних конечностях. Помимо основного заболевания, в анамнезе больного имеется активный хронический вирусный гепатит B, что привлекает внимание к возможной взаимосвязи между вирусной инфекцией и развитием васкулита. Описан механизм возникновения у данного пациента полинейропатии, а также проведенное лечение с использованием глюкокортикоидов и азатиоприна, что позволило стабилизировать состояние. Статья акцентирует внимание на важности комплексной диагностики и дифференциального подхода к лечению, особенно в контексте сочетания вирусного гепатита и аутоиммунных заболеваний.

The present article describes a rare clinical case of eosinophilic granulomatosis with polyangiitis in a 63-year-old patient presenting with polyneuropathy, marked weight loss, and vasculitis rash on the lower extremities. In addition to the primary disease, the patient had a history of active chronic hepatitis B virus infection, drawing attention to a possible association between viral infection and the development of vasculitis. The pathophysiological mechanisms underlying the development of polyneuropathy in this patient are discussed, along with the therapeutic approach involving glucocorticoids and azathioprine, which led to clinical stabilization. The article emphasizes the importance of comprehensive diagnostic evaluation and a differential therapeutic strategy, particularly in the context of coexisting viral hepatitis and autoimmune disease.

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The authors declare that there are no conflicts of interest present.