References

rsp

Научно-практическая ревматология

Rheumatology Science and Practice

1995-44841995-4492

IMA-PRESS, LLC

10.47360/1995-4484-2026-109-125

rsp-3907

Research Article

ПЕРЕДОВАЯ

LEADING ARTICLE

Перспективы терапии системных аутоиммунных ревматических заболеваний. Что необходимо знать врачам отделений интенсивной терапии

Prospects for the treatment of systemic autoimmune rheumatic diseases. What intensive care physicians need to know

https://orcid.org/0000-0002-1598-8360

Насонов

Е. Л.

Nasonov

E. L.

Насонов Евгений Львович

115522, Москва, Каширское шоссе, 34а

Evgeny L. Nasonov

115522, Moscow, Kashirskoye Highway, 34A

nasonov@irramn.ru

https://orcid.org/0000-0001-6010-7975

Лысенко

М. А.

Lysenko

M. A.

52 Департамента здравоохранения города Москвы» 123182, Москва, ул. Пехотная, 3

Maryana A. Lysenko

123182, Moscow, Pekhotnaya str., 3

https://orcid.org/0000-0001-5809-6015

Мутовина

З. Ю.

Mutovina

Z. Yu.

52 Департамента здравоохранения города Москвы» 123182, Москва, ул. Пехотная, 3

Zinaida Yu. Mutovina

123182, Moscow, Pekhotnaya str., 3

https://orcid.org/0000-0002-3235-1425

Загребнева

А. И.

Zagrebneva

A. I.

52 Департамента здравоохранения города Москвы» 123182, Москва, ул. Пехотная, 3

Alena I. Zagrebneva

123182, Moscow, Pekhotnaya str., 3

https://orcid.org/0000-0002-6906-0621

Николаева

Е. В.

Nikolaeva

E. V.

115522, Москва, Каширское шоссе, 34а

Ekaterina V. Nikolaeva

115522, Moscow, Kashirskoye Highway, 34A

https://orcid.org/0000-0002-3248-6426

Ананьева

Л. П.

Ananyeva

L. P.

115522, Москва, Каширское шоссе, 34а

Lidia P. Ananyeva

115522, Moscow, Kashirskoye Highway, 34A

https://orcid.org/0000-0003-2641-9785

Бекетова

Т. В.

Beketova

T. V.

115522, Москва, Каширское шоссе, 34а; 121356, Москва, ул. Маршала Тимошенко, 15; 107023, Москва, ул. Большая Семеновская, 38

Tatiana V. Beketova

115522, Moscow, Kashirskoye Highway, 34A; 121359, Moscow, Marshala Timoshenko str., 19, building 1A; 107023, Moscow, Bolshaya Semyonovskaya str., 38

https://orcid.org/0000-0003-3552-2522

Решетняк

Т. М.

Reshetnyak

T. M.

115522, Москва, Каширское шоссе, 34а

Tatiana M. Reshetnyak

115522, Moscow, Kashirskoye Highway, 34A

https://orcid.org/0000-0002-5206-1732

Соловьев

С. К.

Solovyev

S. K.

115522, Москва, Каширское шоссе, 34а

Sergey K. Solovyev

115522, Moscow, Kashirskoye Highway, 34A

https://orcid.org/0000-0002-1663-7810

Асеева

Е. А.

Aseeva

E. A.

115522, Москва, Каширское шоссе, 34а

Elena A. Aseeva

115522, Moscow, Kashirskoye Highway, 34A

https://orcid.org/0000-0002-7410-9784

Клименко

А. А.

Klimenko

A. A.

117997, Москва, ул. Островитянова, 1

Alesya A. Klimenko

17997, Moscow, Ostrovitianova str., 1

https://orcid.org/0000-0003-1784-3699

Волков

А. В.

Volkov

A. V.

115522, Москва, Каширское шоссе, 34а

Alexander V. Volkov

115522, Moscow, Kashirskoye Highway, 34A

ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»РоссияV.A. Nasonova Research Institute of RheumatologyRussian Federation

ГБУЗ «Московский клинический научно-исследовательский центр Больница 52 Департамента здравоохранения города Москвы»РоссияMoscow Regional Clinical Research Center Hospital No. 52 of the Moscow Health DepartmentRussian Federation

ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»; ФГБУ «Центральная клиническая больница с поликлиникой» Управления делами Президента Российской Федерации; ФГАОУ ВО «Московский политехнический университет»РоссияV.A. Nasonova Research Institute of Rheumatology; Central State Medical Academy of the Administrative Directorate of the President of the Russian Federation; Moscow Polytechnic UniversityRussian Federation

ФГАОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава РоссииРоссияN.I. Pirogov Russian National Research Medical UniversityRussian Federation

2026

01052026

642109125

2026

Насонов Е.Л., Лысенко М.А., Мутовина З.Ю., Загребнева А.И., Николаева Е.В., Ананьева Л.П., Бекетова Т.В., Решетняк Т.М., Соловьев С.К., Асеева Е.А., Клименко А.А., Волков А.В.

Nasonov E.L., Lysenko M.A., Mutovina Z.Y., Zagrebneva A.I., Nikolaeva E.V., Ananyeva L.P., Beketova T.V., Reshetnyak T.M., Solovyev S.K., Aseeva E.A., Klimenko A.A., Volkov A.V.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://rsp.mediar-press.net/rsp/article/view/3907

В спектре ревматических заболеваний особый интерес привлекают системные аутоиммунные ревматические заболевания (САРЗ). Несмотря на кардинальное улучшение прогноза при САРЗ, связанное с совершенствованием стратегии терапии (лечение до достижения цели) и внедрением новых эффективных антивоспалительных препаратов, более чем у 10% пациентов с САРЗ развивается тяжелая органная патология, потенциально требующая лечения в условиях отделений интенсивной терапии (ОИТ). В статье представлен анализ клинико-патологических проявлений, определяющих «тяжелое» течение САРЗ. Обсуждаются перспективы фармакотерапии пациентов с САРЗ в условиях ОИТ. Статья открывает серию планируемых в журнале публикаций, касающихся диагностики и лечения тяжелых осложнений САРЗ.

In the spectrum of rheumatic diseases, systemic autoimmune rheumatic diseases (SARDs) are of particular interest. Despite the dramatic improvement in the prognosis for SARD, associated with the improvement of the treatment strategy (treat-to-target) and the introduction of new effective anti-inflammatory drugs, more than 10% of patients with SARD develop severe organ pathology, potentially requiring treatment in intensive care units (ICUs). This article presents an analysis of the clinical and pathological manifestations that define the “severe” course of SARS. The prospects for pharmacotherapy for patients with SARS in the ICU setting are also discussed. The article opens a series of planned publications in the journal concerning the diagnosis and treatment of severe complications of SARDs.

системные аутоиммунные ревматические заболеванияотделение интенсивной терапиисистемная красная волчанкасистемная склеродермиясистемные васкулитыидиопатические воспалительные миопатииантифосфолипидный синдромантивовоспалительная терапия

systemic autoimmune rheumatic diseasesintensive care unitsystemic lupus erythematosussystemic sclerosissystemic vasculitisidiopathic inflammatory myopathiesantiphospholipid syndromeanti-inflammatory therapy

Исследование не имело спонсорской поддержки

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The authors declare that there are no conflicts of interest present.