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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rsp</journal-id><journal-title-group><journal-title xml:lang="ru">Научно-практическая ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Rheumatology Science and Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-4484</issn><issn pub-type="epub">1995-4492</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1995-4484-2000-151</article-id><article-id custom-type="elpub" pub-id-type="custom">rsp-486</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>ЦЕЛЕБРЕКС - ПЕРВЫЙ СПЕЦИФИЧЕСКИЙ ИНГИБИТОР ЦОГ-2: НОВЫЕ ДАННЫЕ</article-title><trans-title-group xml:lang="en"><trans-title>CELEBREX: THE FIRST SPECIFIC INHIBITOR OF COX-2: NEW DATA</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Nassonov</surname><given-names>E L</given-names></name><name name-style="western" xml:lang="en"><surname>Nassonov</surname><given-names>E L</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра ревматологии</p></bio><bio xml:lang="en"><p>Kafedra revmatologii</p></bio><email xlink:type="simple">-</email></contrib></contrib-group><pub-date pub-type="collection"><year>2000</year></pub-date><pub-date pub-type="epub"><day>15</day><month>08</month><year>2000</year></pub-date><volume>38</volume><issue>4</issue><issue-title>№4 (2000)</issue-title><fpage>3</fpage><lpage>3</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Nassonov E.L., 2000</copyright-statement><copyright-year>2000</copyright-year><copyright-holder xml:lang="ru">Nassonov E.L.</copyright-holder><copyright-holder xml:lang="en">Nassonov E.L.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://rsp.mediar-press.net/rsp/article/view/486">https://rsp.mediar-press.net/rsp/article/view/486</self-uri></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">&lt;div&gt;&lt;p&gt;Насонов Е.Л., Цветкова Е.С., Тов H.JT. Селективные ингибиторы циклооксигеназы-2: новые перспективы лечения заболеваний человека. Тер. Архив, 1998, 5, 8-14.&lt;/p&gt;&lt;p&gt;Насонов Е.Л. Целекоксиб - первый специфический ингибитор циклооксигеназы 2. Русский медицинский журнал, 1999, 12, 580-585.&lt;/p&gt;&lt;p&gt;Насонов Е.Л. Специфические ингибиторы циклооксигеназы (ЦОГ)-2, решенные и не решенные проблемы. Клин, фармакология и терапия, 2000, 1, 57-64.&lt;/p&gt;&lt;p&gt;Насонов Е.Л. Нестероидные противовоспалительные препараты. (Перспективы применения в медицине), Москва, 2000, 262.&lt;/p&gt;&lt;p&gt;Akdamar К., Ertan A., Agarwal N.M., et al. Upper gastrointestinal endoscopy in normal asymptomatic volunteers. Gastrointest. Endoscopy, 1986,32,78-80.&lt;/p&gt;&lt;p&gt;Bensen W.G., Fiectner J.J., McMiller J.I., et al. T reatment of osteoarthritis with celecoxib. A cycloox- ygenase-2 inhibitors: a randomized controlled trial. Mayo Clin. Proc., 1999, 74, 1095-1105.&lt;/p&gt;&lt;p&gt;DuBois R.N., Abramson S.B., Crofford L., et al. Cyclooxygenase in biology and medicine. FASEB J., 1998, 12, 1063-1073.&lt;/p&gt;&lt;p&gt;Emery P., Zeidler H., Kvien Т.К., et al. Celecoxib versus diclofenac in long-term management of rheumatoid arthritis: randomized double-blind comparison. Lancet, 1999, 354, 2106-2111.&lt;/p&gt;&lt;p&gt;Feldman М., McMachon A.T. Do cyclooxigenase-2 inhibitors provide benefits similar to those of traditional nonsteroidal anti-inflammatory drugs, with less gastrointerstinal toxicitv. Ann. Intern. Med., 2000, 132, 134-143.&lt;/p&gt;&lt;p&gt;Geis G.S., Fitzgerald G. A., Karim A., et al. A comparative study of platelet function in subjects receiving either celecoxib, a specific COX-2 inhibitor, or ibuprofen, a nonspecific inhibitor of cyclooxygenase. XV European League Against Rheumatism (EULAR) Congress, Nice, June 2000 (abst.).&lt;/p&gt;&lt;p&gt;Goldstein J., Whelton A., Faich G. Celecoxib safety and tolerability profile: GI and beyond, with perspectives on celecoxib cardiovascular effects.Satelliye Symposium at the XV European League Against Rheumatism (EULAR) Congress, Nice, June 2000.&lt;/p&gt;&lt;p&gt;Hawkey C.J. COX-2 inhibitors. Lancet, 1999, 353, 307-314.&lt;/p&gt;&lt;p&gt;IhmakiТ., VarisK.,Siurala M. Morphological, functional and immunological state of the gastric mucosa in gastric carcinoma families. Scand. J. Gastroenterol., 1979, 14, 801-812.&lt;/p&gt;&lt;p&gt;Kaplan-Machiis B., Kiostermeyer B.S. The cycloox- iygenase-2 inhibitors: safety and effectiveness. Ann. Pharmacotherapy, 1999, 33, 979-988.&lt;/p&gt;&lt;p&gt;Kolondy A.L. Two double blind trials of diclofenac sodium with aspirin and with naproxen in the treatment of rheumatoid arthritis. J. Rheumatol., 1988, 15, 1205-1211.&lt;/p&gt;&lt;p&gt;Lipsky P.E., Abramson S.B., Crofford L., et al. The classification of cyclooxygenase inhibitors. J. Rheumatol., 1998, 25, 2298-2302.&lt;/p&gt;&lt;p&gt;Needleman P., Isacson P.C. The discovery and function of COX-2. J. Rheumatol., 1997, 24, 6-7.&lt;/p&gt;&lt;p&gt;Peterson W.L.,Cryer В.COX-1-SparingNSAIDs-is theenthusiasm justified? JAMA, 1999,282,1961-1963.&lt;/p&gt;&lt;p&gt;Singh G. Celecoxib use in patients: the spectrum and everyday experience. Satellite Symposium at the XV European League Against Rheumatism (ELTLAR) Congress, Nice, June 2000.&lt;/p&gt;&lt;p&gt;Singh G., Ramey D.R., Triadafilopoulos Experience with selective COX-2 inhibitors: safety profile in over 780000 patient years of use. XV European League Against Rheumatism (EULAR) Congress, Nice, June 2000 (abst.).&lt;/p&gt;&lt;p&gt;Simon L.S., Weaver A.L., Graham D.Y., et al. Antiinflammatory and upper gastrointestinal effects of celecoxib in rheumatoid arthritis. JAMA, 1999, 282, 1921-1928.&lt;/p&gt;&lt;p&gt;Vane J. Towards a better aspirin. Nature, 1994, 367, 215-216.&lt;/p&gt;&lt;/div&gt;&lt;br /&gt;</mixed-citation><mixed-citation xml:lang="en">&lt;div&gt;&lt;p&gt;Насонов Е.Л., Цветкова Е.С., Тов H.JT. Селективные ингибиторы циклооксигеназы-2: новые перспективы лечения заболеваний человека. Тер. Архив, 1998, 5, 8-14.&lt;/p&gt;&lt;p&gt;Насонов Е.Л. Целекоксиб - первый специфический ингибитор циклооксигеназы 2. Русский медицинский журнал, 1999, 12, 580-585.&lt;/p&gt;&lt;p&gt;Насонов Е.Л. Специфические ингибиторы циклооксигеназы (ЦОГ)-2, решенные и не решенные проблемы. Клин, фармакология и терапия, 2000, 1, 57-64.&lt;/p&gt;&lt;p&gt;Насонов Е.Л. Нестероидные противовоспалительные препараты. (Перспективы применения в медицине), Москва, 2000, 262.&lt;/p&gt;&lt;p&gt;Akdamar К., Ertan A., Agarwal N.M., et al. Upper gastrointestinal endoscopy in normal asymptomatic volunteers. Gastrointest. Endoscopy, 1986,32,78-80.&lt;/p&gt;&lt;p&gt;Bensen W.G., Fiectner J.J., McMiller J.I., et al. T reatment of osteoarthritis with celecoxib. A cycloox- ygenase-2 inhibitors: a randomized controlled trial. Mayo Clin. Proc., 1999, 74, 1095-1105.&lt;/p&gt;&lt;p&gt;DuBois R.N., Abramson S.B., Crofford L., et al. Cyclooxygenase in biology and medicine. FASEB J., 1998, 12, 1063-1073.&lt;/p&gt;&lt;p&gt;Emery P., Zeidler H., Kvien Т.К., et al. Celecoxib versus diclofenac in long-term management of rheumatoid arthritis: randomized double-blind comparison. Lancet, 1999, 354, 2106-2111.&lt;/p&gt;&lt;p&gt;Feldman М., McMachon A.T. Do cyclooxigenase-2 inhibitors provide benefits similar to those of traditional nonsteroidal anti-inflammatory drugs, with less gastrointerstinal toxicitv. Ann. Intern. Med., 2000, 132, 134-143.&lt;/p&gt;&lt;p&gt;Geis G.S., Fitzgerald G. A., Karim A., et al. A comparative study of platelet function in subjects receiving either celecoxib, a specific COX-2 inhibitor, or ibuprofen, a nonspecific inhibitor of cyclooxygenase. XV European League Against Rheumatism (EULAR) Congress, Nice, June 2000 (abst.).&lt;/p&gt;&lt;p&gt;Goldstein J., Whelton A., Faich G. Celecoxib safety and tolerability profile: GI and beyond, with perspectives on celecoxib cardiovascular effects.Satelliye Symposium at the XV European League Against Rheumatism (EULAR) Congress, Nice, June 2000.&lt;/p&gt;&lt;p&gt;Hawkey C.J. COX-2 inhibitors. Lancet, 1999, 353, 307-314.&lt;/p&gt;&lt;p&gt;IhmakiТ., VarisK.,Siurala M. Morphological, functional and immunological state of the gastric mucosa in gastric carcinoma families. Scand. J. Gastroenterol., 1979, 14, 801-812.&lt;/p&gt;&lt;p&gt;Kaplan-Machiis B., Kiostermeyer B.S. The cycloox- iygenase-2 inhibitors: safety and effectiveness. Ann. Pharmacotherapy, 1999, 33, 979-988.&lt;/p&gt;&lt;p&gt;Kolondy A.L. Two double blind trials of diclofenac sodium with aspirin and with naproxen in the treatment of rheumatoid arthritis. J. Rheumatol., 1988, 15, 1205-1211.&lt;/p&gt;&lt;p&gt;Lipsky P.E., Abramson S.B., Crofford L., et al. The classification of cyclooxygenase inhibitors. J. Rheumatol., 1998, 25, 2298-2302.&lt;/p&gt;&lt;p&gt;Needleman P., Isacson P.C. The discovery and function of COX-2. J. Rheumatol., 1997, 24, 6-7.&lt;/p&gt;&lt;p&gt;Peterson W.L.,Cryer В.COX-1-SparingNSAIDs-is theenthusiasm justified? JAMA, 1999,282,1961-1963.&lt;/p&gt;&lt;p&gt;Singh G. Celecoxib use in patients: the spectrum and everyday experience. Satellite Symposium at the XV European League Against Rheumatism (ELTLAR) Congress, Nice, June 2000.&lt;/p&gt;&lt;p&gt;Singh G., Ramey D.R., Triadafilopoulos Experience with selective COX-2 inhibitors: safety profile in over 780000 patient years of use. XV European League Against Rheumatism (EULAR) Congress, Nice, June 2000 (abst.).&lt;/p&gt;&lt;p&gt;Simon L.S., Weaver A.L., Graham D.Y., et al. Antiinflammatory and upper gastrointestinal effects of celecoxib in rheumatoid arthritis. JAMA, 1999, 282, 1921-1928.&lt;/p&gt;&lt;p&gt;Vane J. Towards a better aspirin. Nature, 1994, 367, 215-216.&lt;/p&gt;&lt;/div&gt;&lt;br /&gt;</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
