rspНаучно-практическая ревматологияRheumatology Science and Practice1995-44841995-4492IMA-PRESS, LLC10.14412/1995-4484-2008-432rsp-570Research ArticleСтатьиArticlesАдалимумаб в терапии раннего ревматоидного артритаAdalimumab in the treatment of early rheumatoid arthritisСигидинЯ. А.SigidinY A-ЛукинаГ. В.LukinaG. V.-200815042008462№2 (2008)5659Copyright © Сигидин Я.А., Лукина Г.В., 20082008Сигидин Я.А., Лукина Г.В.Sigidin Y.A., Lukina G.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://rsp.mediar-press.net/rsp/article/view/570References<div><p>Насонов Е.Л. Лечение ревматоидного артрита: современное состояние проблемы. Русский мед. журнал, 2006, №8, 573-577</p><p>Насонов Е.Л. Перспективы применения полностью человеческих моноклональных антител к фактору некроза опухоли (адалимумаб) при ревматоидном артрите. Клин, фармакол. терапия, 2007, 1, 71-74.</p><p>Алекберова З.С. Адалимумаб в терапии ревматоидного артрита. Научно-практ. ревматология. 2007, 4, 103-108.</p><p>Сигидин Я.А., Лукина Г. В. Биологическая терапия в ревматологии. М., 2007, 180.</p><p>Kempeni J. Preliminary results of early clinical trials with the fully human anti-TNFa monoclonal antibody D2E7.Ann.Rheum.Dis., 1999, 58, 1, 170-172.</p><p>Weinblatt M.E., Keystone E.C., Furst D.E. et al. Long term efficacy and safety of adalimumab plus methotrexate in patients with rheumatoid arthritis: ARMADA year extended study. Ann.Rheum.Dis., 2006, 65, 753-759.</p><p>Weisman М., Moreland L., Furst D., et al. Efficacy, pharmacokinetic, and safety assessment of adalimumab, a fully human anti-tumour necrosis factor- alpha monoclonal antibody, in adults with rheumatoid arthritis receiving concomitant methotrexate: a pilot study. Clin. Therapeutics, 2003, 25, 1700-1721.</p><p>Keystone E.C., Kavanaugh A.F., Sharp J.T. et al. Radiographic, clinical and functional outcomes of treatment with adalimumab in patients with active rheumatoid arthritis receiving concomitant methotrexate therapy. Arthr.Rheum., 2004, 50, 1400-1411.</p><p>Bombardieri S., Ruiz A.A., Fardellone P. et al. Effectiveness of adalimumab for rheumatoid arthritis in patients with a history of TNF-antagonist therapy in clinical practice. Rheumatology, 2007, advance access May 15, doi "10.1093/rheumatology/kem 091.</p><p>StClaire E. W., van der Heijde D. V., Smolen J.S. et al. Active-controlled study of patients receiving infliximab for the treatment of rheumatoid arthritis of early onset study group. Arthr. Rheum., 2004, 50, 3432-3443.</p><p>Klareskog L., van der Heijde D., de Jager J.P. et al. Therapeutic effect of the combination of etanercept and methotrexate compared with each treatment alone in patients with rheumatoid arthritis. Lancet, 2004, 363, 675-681.</p><p>Breedveld F.C., Weisman M.H., Kavanaugh A.F. et al. The PREMIER Study. A multicenter, randomized, double-blind clinical study of combination therapy with adalimumab and methotrexate versus methotrexate alone or adalimumab alone in patients with early, aggressive rheumatoid arthritis who had not had previous methotrexate therapy. Arthr.Rheum., 2006, 54, 26-37.</p><p>Van der Heijde D. М., How to read radiographs according to the Sharp/van der Heijde method. J. Rheumatol., 1999, 26, 743-745.</p><p>Hoff М., Kvien Т., Kaelvesten J. et al. Anti-TNF treatment with adalimumab reduces hand bone loss in early rheumatoid arthritis: Explorative analysis from the PREMIER study. Arthr.Rheum., 2007, 56, suppl., S. 152-153.</p><p>Keystone E.C., Haraoui D., Bykerk V.P. Role of adalimumab in the treatment of early rheumatoid arthritis. Clin.Exper.Rheumatol., 2003, 21, suppl.31, S198-199.</p><p>Bejarano V. Quinn М., Conaghan P.G. et al. Adalimumab plus methotrexate improves work stability and reduces job loss in early rheumatoid arthritis (RA): Results of the PRevention Of Work Disability (PROWD) study. Ann.Rheum.Dis.,2007,66,suppl. 11,176.</p><p>Halpern M.T., Cifaldi М., Quien T. Impact of adalimumab on rheumatoid arthritis (RA) outcomes: Comparison of an open-label extension study and a registry-based control group. Ann.Rheum.Dis., 2007, 66, suppl.II, 171.</p><p>Weinblatt ME, et al. Arthritis Rheum. 2003;48:35-45</p></div><br /><div><p>Насонов Е.Л. Лечение ревматоидного артрита: современное состояние проблемы. Русский мед. журнал, 2006, №8, 573-577</p><p>Насонов Е.Л. Перспективы применения полностью человеческих моноклональных антител к фактору некроза опухоли (адалимумаб) при ревматоидном артрите. Клин, фармакол. терапия, 2007, 1, 71-74.</p><p>Алекберова З.С. Адалимумаб в терапии ревматоидного артрита. Научно-практ. ревматология. 2007, 4, 103-108.</p><p>Сигидин Я.А., Лукина Г. В. Биологическая терапия в ревматологии. М., 2007, 180.</p><p>Kempeni J. Preliminary results of early clinical trials with the fully human anti-TNFa monoclonal antibody D2E7.Ann.Rheum.Dis., 1999, 58, 1, 170-172.</p><p>Weinblatt M.E., Keystone E.C., Furst D.E. et al. Long term efficacy and safety of adalimumab plus methotrexate in patients with rheumatoid arthritis: ARMADA year extended study. Ann.Rheum.Dis., 2006, 65, 753-759.</p><p>Weisman М., Moreland L., Furst D., et al. Efficacy, pharmacokinetic, and safety assessment of adalimumab, a fully human anti-tumour necrosis factor- alpha monoclonal antibody, in adults with rheumatoid arthritis receiving concomitant methotrexate: a pilot study. Clin. Therapeutics, 2003, 25, 1700-1721.</p><p>Keystone E.C., Kavanaugh A.F., Sharp J.T. et al. Radiographic, clinical and functional outcomes of treatment with adalimumab in patients with active rheumatoid arthritis receiving concomitant methotrexate therapy. Arthr.Rheum., 2004, 50, 1400-1411.</p><p>Bombardieri S., Ruiz A.A., Fardellone P. et al. Effectiveness of adalimumab for rheumatoid arthritis in patients with a history of TNF-antagonist therapy in clinical practice. Rheumatology, 2007, advance access May 15, doi "10.1093/rheumatology/kem 091.</p><p>StClaire E. W., van der Heijde D. V., Smolen J.S. et al. Active-controlled study of patients receiving infliximab for the treatment of rheumatoid arthritis of early onset study group. Arthr. Rheum., 2004, 50, 3432-3443.</p><p>Klareskog L., van der Heijde D., de Jager J.P. et al. Therapeutic effect of the combination of etanercept and methotrexate compared with each treatment alone in patients with rheumatoid arthritis. Lancet, 2004, 363, 675-681.</p><p>Breedveld F.C., Weisman M.H., Kavanaugh A.F. et al. The PREMIER Study. A multicenter, randomized, double-blind clinical study of combination therapy with adalimumab and methotrexate versus methotrexate alone or adalimumab alone in patients with early, aggressive rheumatoid arthritis who had not had previous methotrexate therapy. Arthr.Rheum., 2006, 54, 26-37.</p><p>Van der Heijde D. М., How to read radiographs according to the Sharp/van der Heijde method. J. Rheumatol., 1999, 26, 743-745.</p><p>Hoff М., Kvien Т., Kaelvesten J. et al. Anti-TNF treatment with adalimumab reduces hand bone loss in early rheumatoid arthritis: Explorative analysis from the PREMIER study. Arthr.Rheum., 2007, 56, suppl., S. 152-153.</p><p>Keystone E.C., Haraoui D., Bykerk V.P. Role of adalimumab in the treatment of early rheumatoid arthritis. Clin.Exper.Rheumatol., 2003, 21, suppl.31, S198-199.</p><p>Bejarano V. Quinn М., Conaghan P.G. et al. Adalimumab plus methotrexate improves work stability and reduces job loss in early rheumatoid arthritis (RA): Results of the PRevention Of Work Disability (PROWD) study. Ann.Rheum.Dis.,2007,66,suppl. 11,176.</p><p>Halpern M.T., Cifaldi М., Quien T. Impact of adalimumab on rheumatoid arthritis (RA) outcomes: Comparison of an open-label extension study and a registry-based control group. Ann.Rheum.Dis., 2007, 66, suppl.II, 171.</p><p>Weinblatt ME, et al. Arthritis Rheum. 2003;48:35-45</p></div><br />
The authors declare that there are no conflicts of interest present.