rspНаучно-практическая ревматологияRheumatology Science and Practice1995-44841995-4492IMA-PRESS, LLC10.14412/1995-4484-2001-478rsp-616Research ArticleСтатьиArticlesПСЕВДОСКЛЕРОДЕРМИЧЕСКИЙ СИНДРОМ ПРИ САХАРНОМ ДИАБЕТЕPSEUDOSCLERODERMAL SYNDROME IN DIABETES MELLITUSНевскаяТ. А.NevskayaT. A.-GousevaN. G.GousevaN. G.-200115102001395№5 (2001)7984Copyright © Невская Т.А., Gouseva N.G., 20012001Невская Т.А., Gouseva N.G.Nevskaya T.A., Gouseva N.G.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://rsp.mediar-press.net/rsp/article/view/616

Skin thicking simulating scleroderma is not rare in diabetes mellitus (about 2% among patients with diabetes mellitus), however it is not well known to rheumatologists and endocrinologists. The basis of the syndrome are the abnormalities of collagen and glycosaminoglycans metabolism accompanying by the acid mucopolysaccharides accumulation in the deep part of the reticular dermis. Three cases of pseudosclerodrma in patients with long-standing complicated insulin-dependent diabetes mellitus are presented. The main clinical manifestations of pseudoscleroderma were marked cutaneous induration of the neck, body and proximal parts of extremities liked that of scleredema of Buschke ( 2 patients), and primary paraarticular induration leaded to the flexion contractures liked that of paraneoplastic scleroderma ( I patient). Possible mechanisms of development, clinical and morphological peculiarities and treatment for this syndrome are discussed.

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The authors declare that there are no conflicts of interest present.