<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rsp</journal-id><journal-title-group><journal-title xml:lang="ru">Научно-практическая ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Rheumatology Science and Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-4484</issn><issn pub-type="epub">1995-4492</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1995-4484-2011-604</article-id><article-id custom-type="elpub" pub-id-type="custom">rsp-742</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>БОЛЕЗНЬ СТИЛЛА, РАЗВИВШАЯСЯ У ВЗРОСЛЫХ</article-title><trans-title-group xml:lang="en"><trans-title>Adult-onset Still's disease</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Murav'ev</surname><given-names>Yu V</given-names></name><name name-style="western" xml:lang="en"><surname>Murav'ev</surname><given-names>Yu V</given-names></name></name-alternatives><email xlink:type="simple">murawyu@mail.ru  &amp;lt;mailto:murawyu@mail.ru&amp;gt;</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Насонов</surname><given-names>Евгений Львович</given-names></name><name name-style="western" xml:lang="en"><surname>Nasonov</surname><given-names>E L</given-names></name></name-alternatives><email xlink:type="simple">murawyu@mail.ru</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Муравьев</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Muravyev</surname><given-names>Yu V</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Насонов</surname><given-names>Евгений Львович</given-names></name><name name-style="western" xml:lang="en"><surname>Nasonov</surname><given-names>E L</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib></contrib-group><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>15</day><month>04</month><year>2011</year></pub-date><volume>49</volume><issue>2</issue><issue-title>№2 (2011)</issue-title><fpage>58</fpage><lpage>65</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Murav'ev Y.V., Насонов Е.Л., Муравьев Ю.В., Насонов Е.Л., 2011</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="ru">Murav'ev Y.V., Насонов Е.Л., Муравьев Ю.В., Насонов Е.Л.</copyright-holder><copyright-holder xml:lang="en">Murav'ev Y.V., Nasonov E.L., Muravyev Y.V., Nasonov E.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://rsp.mediar-press.net/rsp/article/view/742">https://rsp.mediar-press.net/rsp/article/view/742</self-uri></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">&lt;div&gt;&lt;p&gt;Международная статистическая классификация болезней и проблем, связанных со здоровьем;10-й пересмотр. Женева: ВОЗ, 1995.&lt;/p&gt;&lt;p&gt;Efthimiou P., Paik P.K., Bielory L. Diagnosis and management of adult onset Still's disease. Ann Rheum Dis 2006;65:564-72.&lt;/p&gt;&lt;p&gt;Bannatyne G.A., Wohlmann A.S. Rheumatoid Arthritis: Its clinical history, etiology and pathology. Lancet 1896;1:1120-5.&lt;/p&gt;&lt;p&gt;Still G.F. On a form of chronic joint disease in children. Med Chir Trans 1897;80:47-65.&lt;/p&gt;&lt;p&gt;Reimann H.A., de Bardinis C.T. Periodic cyclic neutropenia, an entity. Blood 1949;4:1109-16.&lt;/p&gt;&lt;p&gt;Wissler H. Uber eine besondere Form sepsisahnlicher krankheiten (subsepsishyperergica). Z Kinderheilkd 1964;94:1-23.&lt;/p&gt;&lt;p&gt;Hegglin R., Uehlinger E. Klinische Demonstrationen: Febris periodica hyperergica. Schweiz Med Wschr 1964;94:675-85.&lt;/p&gt;&lt;p&gt;Fanconi G. Uber einen Fall von Subsepsis allergica Wissler. Helv Paediatr Acta 1946;1:532-7.&lt;/p&gt;&lt;p&gt;Riolet J. Syndrome de Wissler-Fanconi. Rev Rhum Mal Osteartic 1964;31:388-97.&lt;/p&gt;&lt;p&gt;Larson E.B. Adult Still's disease - recognition of a clinical syndrome and recent experience. West J Med 1985;142:665-71.&lt;/p&gt;&lt;p&gt;Wissler H. Subsepsis allergica. Ergeb Inn Med Kinderheilkd 1965;23:202-20.&lt;/p&gt;&lt;p&gt;Bywaters E.G. Still's disease in the adult. Ann Rheum Dis 1971;30:121-33.&lt;/p&gt;&lt;p&gt;Bywaters E.G. Categorization in medicine: A survey of Still's disease. Ann Rheum Dis 1967;26:185-93.&lt;/p&gt;&lt;p&gt;Bujak J.S., Aptekar R.G., Decker J.L. et al. Juvenile rheumatoid arthritis in theadult presenting as fever of unknown origin. Medicine (Baltimore) 1973;52:431-44.&lt;/p&gt;&lt;p&gt;Fabricant M.S., Chander S.B., Friou G.J. Still's disease in adults: A cause of prolonged undiagnosed fever. JAMA 1973;225:273-5.&lt;/p&gt;&lt;p&gt;Caroit M., Mathieu M., Kahn M.F. et al. Maladie de Still de l'adulte et syndrome de Wissler-Fanconi. Rev Rhum Mal Osteartic 1973;40:1-8.&lt;/p&gt;&lt;p&gt;Calabro J.J., Marchesano J.M. Fever associated with juvenile rheumatoid arthritis. N Engl J Med 1967;276:1-18.&lt;/p&gt;&lt;p&gt;Isdaile I.C., Bywaters E.G. The rash in Still's disease. Quart J Med 1956;25:377-87.&lt;/p&gt;&lt;p&gt;Calabro J.J., Cruess R.L., Levinson J.E. et al. Juvenile rheumatoid arthritis. Patient Care 1977;11:70-116.&lt;/p&gt;&lt;p&gt;Elkon K.B., Hughes G.R., Bywaters E.G. et al. Adult onset Still's disease: Twenty-year follow-up and further studies of patients with active disease. Arthr Rheum 1982;25:647-53.&lt;/p&gt;&lt;p&gt;Medsger T.A., Christy W.C. Carpal arthritis with ankylosis in late-onset Still's disease. Arthr Rheum 1976;19:232-42.&lt;/p&gt;&lt;p&gt;Healey L.A., Willkens R.F. Tarsal arthritis with ankylosis in late-onset Still's disease. Arthr Rheum 1982;25:1254-6.&lt;/p&gt;&lt;p&gt;Jamieson T.W. Adult Still's disease complicated by cardiac tamponade. JAMA 1983;249:2065-6.&lt;/p&gt;&lt;p&gt;Tesser J.R., Pisko E.J., Hartz J.W. et al. Chronic liver disease and adult Still's disease. Arthr Rheum 1982;25:579-82.&lt;/p&gt;&lt;p&gt;Baker D.G., Schumacher H.R., Reginato A.J. Fifteen patients with adult onset Still's disease: Life-threatening liver failure in two (Abstr). Arthr Rheum 1979;22:590.&lt;/p&gt;&lt;p&gt;Masson C., Le Loët X., Liote F. et al. Adult Still's disease: part I. Manifestations and complications in sixty-five cases in France. Rev Rhum Engl Ed 1995;62:748-57.&lt;/p&gt;&lt;p&gt;Pelkonen P., Swanliung K., Siimes M.A. Ferritinemia as an indicator of systemic disease activity in children with systemic juvenile rheumatoid arthritis. Acta Paediatr Scand 1986;75:64-8.&lt;/p&gt;&lt;p&gt;Gonzalez-Hernandez T., Martin-Mola E., Femandez-Zamoeano A. et al. Serum ferritin can be useful for diagnosis in adult onset Still's disease. J Rheumatol 1989;16:412-3.&lt;/p&gt;&lt;p&gt;Fautrel B., Le Moel G., Saint-Marcoux B. et al. Diagnostic value of ferritin and glycosylated ferritin in adult onset Still's disease. J Rheumatol 2001;28:322-9.&lt;/p&gt;&lt;p&gt;Fautrel B. Ferritin levels in adult Still's disease: any sugar? J Bone Spine 2002;69:355-7.&lt;/p&gt;&lt;p&gt;Cush J.J. Adult-onset Still's disease. Bull Rheum Dis 2000;49:1-4.&lt;/p&gt;&lt;p&gt;Van Reeth C., Le Moel G., Lasne Y. et al. Serum ferritin and isoferritins are tools for diagnosis of active adult Still's dis ease. J Rheumatol 1994;21:890-5.&lt;/p&gt;&lt;p&gt;Akritidis N., Giannakakis I., Giouglis T. Ferritin levels and response to treatment in patients with adult Still's disease. J Rheumatol 1996;23:201-2.&lt;/p&gt;&lt;p&gt;Magadur-Joly G., Billaud E., Barrier J.H. et al. Epidemiology of adult Still's disease: estimate of the incidence by a retrospective study in west France. Ann Rheum Dis 1995;54:587-90.&lt;/p&gt;&lt;p&gt;Wakai K., Ohta A., Tamakoshi A. et al. Estimated prevalence and incidence of adult Still's disease: findings by anationwide epidemiological survey in Japan. J Epidemiol 1997;7:221-5.&lt;/p&gt;&lt;p&gt;Ohta A., Yamaguchi M., Tsunematsu T. et al. Adult Still's disease: a multicenter survey of Japanese patients. J Rheumatol 1990;17:1058-63.&lt;/p&gt;&lt;p&gt;Van de Putte L.B., Wouters J.M. Adultonset Still's disease. Bailliere's Clin Rheumatol 1991;5:263-75.&lt;/p&gt;&lt;p&gt;Wouters J.M., van de Putte L.B. Adultonset Still's disease; clinical and laboratory features, treatment and progress of 45 cases. Quart J Med 1986;61:1055-65.&lt;/p&gt;&lt;p&gt;Sampalis J.S., Medsger T.A., Fries J.F. et al. Risk factors for adult Still's disease. J Rheumatol 1996;23:2049-54.&lt;/p&gt;&lt;p&gt;Kontzias A., Efthimiou P. Adult-Onset Still's Disease Pathogenesis, Clinical Manifestations and Therapeutic Advances. Drugs 2008;68:319-37.&lt;/p&gt;&lt;p&gt;Hoshino T., Ohta A., Yang D. et al. Elevated serum interleukin 6, interferongamma, and tumor necrosis factor-alpha levels in patients with adult Still's disease. J Rheumatol 1998;25:396-8.&lt;/p&gt;&lt;p&gt;Ogata A., Kitano M., Yamanaka J. et al. Interleukin 18 and hepatocyte growth factor in fulminant hepatic failure of adult onset Still's disease. J Rheumatol 2003;30:1093-6.&lt;/p&gt;&lt;p&gt;Kotter I., Wacker A., Koch S. et al. Anakinra in patients with treatment-resistant adult-onset Still's disease: four case reports with serial cytokine measurements and a review of the literature. Semin Arthr Rheum 2007;37:189-97.&lt;/p&gt;&lt;p&gt;Jeon Y.K., Paik J.H., Park S.S. et al. Spectrum of lymph node pathology in adult onset Still's disease; analysis of 12 patients with one follow up biopsy. J Clin Pathol 2004;57:1052-6.&lt;/p&gt;&lt;p&gt;Jamin C., Morva A., Lemoine S. et al. Regulatory B lymphocytes in humans. A potential role in autoimmunity. Arthr Rheum 2008;58:1900-6.&lt;/p&gt;&lt;p&gt;Yamaguchi M., Ohta A., Tsunematsu T. et al. Preliminary criteria for classification of adult Still's disease. J Rheumatol 1992;19:424-30.&lt;/p&gt;&lt;p&gt;Cush J.J., Medsger T. Jr., Christy W.C. et al. Adult-onset Still's disease: clinical course and outcome. Arthr Rheum 1987;30:186-94.&lt;/p&gt;&lt;p&gt;Fautrel B., Zing E., Golmard J.L. et al. Proposal for a new set of classification criteria for adult-onset Still disease. Medicine (Baltimore) 2002;81:194-200.&lt;/p&gt;&lt;p&gt;Pouchot J., Sampalis J.S., Beaudet F. et al. Adult Still's disease: manifestations, disease course, and outcome in 62 patients. Medicine (Baltimore) 1991;70:118-36.&lt;/p&gt;&lt;p&gt;Evensen K.J., Nossent H.C. Epidemiology and outcome of adult onset Still's disease in northern Norway. Scand J Rheumatol 2006;35:48-51.&lt;/p&gt;&lt;p&gt;Pay S., Turkcapar N., Kalyoncu M. et al. A multicenter study of patients with adultonset Still's disease compared with systemic juvenile idiopathic arthritis. Clin Rheumatol 2006;25:639-44.&lt;/p&gt;&lt;p&gt;Mandl L., Esdaile J.M. Adult Still's disease. Up To Date. &amp;lt;http://www.uptodate.com/&amp;gt; (accessed 14 February 2006).&lt;/p&gt;&lt;p&gt;Kaplinsky N., Paas M., Frankl О. An adult form of juvenile rheumatoid arthritis. Arch Intern Med 1980;140:1073-4.&lt;/p&gt;&lt;p&gt;Khraishi M., Fam A.G. Treatment of fulminant adult Still's disease with intravenous pulse methylprednisolone therapy. J Rheumatol 1991;18:1088-90.&lt;/p&gt;&lt;p&gt;Bambery P., Thomas R.J., Malhotra H.S. et al. Adult onset Still's disease: clinical experience with 18 patients over 15 years in northern India. Ann Rheum Dis 1992;51:529-32.&lt;/p&gt;&lt;p&gt;Shojania K., Chalmers A., Rangno K. Cyclosporin A in thetreatment of adult Still's disease. J Rheumatol 1995;22:1391-2.&lt;/p&gt;&lt;p&gt;Cefle A. Leflunomide and azathioprine combination in refractory adult-onset Still's disease. Ann Pharmacother 2005;39:764-7.&lt;/p&gt;&lt;p&gt;Murakami K., Fujii T., Yukawa N. et al. Successful treatment of a patient with refractory adult Still's disease by tacrolimus. The Japan Rheum. Association. Modern Rheumatol 2007;17:167-70.&lt;/p&gt;&lt;p&gt;Mahmud T., Hughes G.R. Intravenous immunoglobulin in thetreatment of refractory adult Still's disease. J Rheumatol 1999;26:2067-8.&lt;/p&gt;&lt;p&gt;Vignes S., Wechsler B., Amoura Z. et al. Intravenous immunoglobulin in adult Still's disease refractory to non-steroidal antiinflammatory drugs. Clin Exp Rheumatol 1998;16:295-8.&lt;/p&gt;&lt;p&gt;Bennett A.N., Peterson P., Sangle S. et al. Adult onset Still's disease and collapsing glomerulopathy: successful treatment with intravenous immunoglobulins and mycophenolate mofetil. Rheumatology (Oxford) 2004;43:795-9.&lt;/p&gt;&lt;p&gt;Husni M.E., Maier A.L., Mease P.J. et al. Etanercept in the treatment of adult patients with Still's disease. Arthr Rheum 2002;46:1171-6.&lt;/p&gt;&lt;p&gt;Kuek A., Weerakoon A., Ahmed K. et al. Adult-onset Still's disease and myocarditis: successful treatment with intravenous immunoglobulin and maintenance of remission with etanercept. Rheumatology (Oxford) 2007;46:1043-4.&lt;/p&gt;&lt;p&gt;Cavagna L., Caporali R., Epis O. et al. Infliximab in the treatment of adult Still's disease refractory to conventional therapy. Clin Exp Rheumatol 2001;19:329-32.&lt;/p&gt;&lt;p&gt;Kokkinos A., Iliopoulos A., Greka P. et al. Successful treatment of refractory adultonset Still's disease with infliximab: a prospective, non-comparative series of four patients. Clin Rheumatol 2004;23:45-9.&lt;/p&gt;&lt;p&gt;Huffstutter J., Sienknecht C. Treatment of resistant adult Still's disease with infliximab: a report of 2 cases. J Clin Rheumatol 2004;10:218-21.&lt;/p&gt;&lt;p&gt;Bonilla Hernan M.G., Cobo Ibanez T., de Miguel Mendieta E. et al. Infliximab (anti-TNF-alpha) treatment in patients with adult Still's disease: experience in 2 cases [in Spanish]. Ann Med Interna 2004;21:23-6.&lt;/p&gt;&lt;p&gt;Caramaschi P., Biasi D., Carletto A. et al. A case of adult onset Still's disease treated with infliximab [letter]. Clin Exp Rheumatol 54. 54. 64&lt;/p&gt;&lt;p&gt;Fautrel B., Sibilia J., Mariette X. et al. Tumour necrosis factor alpha blocking agents in refractory adult Still's disease: an observational study of 20 cases. Ann Rheum Dis 2005;64:262-6.&lt;/p&gt;&lt;p&gt;Benucci M., Li G.F., Del Rosso A. et al. Adalimumab (anti-TNF-alpha) therapy to improve the clinical course of adult-onset Still's disease: the first case report [letter]. Clin Exp Rheum 2005;23:733.&lt;/p&gt;&lt;p&gt;Efthimiou P., Georgy S. Pathogenesis and management of adult onset Still's disease. Semin Arthr Rheum 2006;36:144-52.&lt;/p&gt;&lt;p&gt;Godinho F., Santos M.J., Canas Da Silva J. Refractory adult onset Still's disease successfully treated with anakinra. Ann Rheum Dis 2005;64:647-8.&lt;/p&gt;&lt;p&gt;Fitzgerald A.A., Leclercq S.A., Yan A. et al. Rapid responses to anakinra in patients with refractory adult-onset Still's disease. Arthr Rheum 2005;52:1794-803.&lt;/p&gt;&lt;p&gt;Iwamoto M., Nara H., Hirata D. et al. Humanized monoclonal anti-interleukin-6 receptor antibody for treatment of intractable adult-onset Still's disease. Arthr Rheum 2002;46:3388-9.&lt;/p&gt;&lt;p&gt;Kraetsch H.G., Antoni C., Kalden J.R. et al. Successful treatment of a small cohort of patients with adult onset of Still's disease with infliximab: first experiences. Ann Rheum Dis 2001;60(Suppl. 3):55-7.&lt;/p&gt;&lt;p&gt;Dechant C., Schauenberg P., Antoni C.E. et al. Long-term out come of TNF blockade in adult-onset Still's disease [in German]. Dtsch Med Wschr 2004;129:1308-12.&lt;/p&gt;&lt;p&gt;Dilhuydy M.S., Vatan R., Etienne G. et al. Prolonged efficacy of infliximab for refractory adult-onset Still's disease. Clin Exp Rheumatol 2005;23:121-2.&lt;/p&gt;&lt;p&gt;Michel M., Duvoux C., Hezode C. et al. Fulminant hepatitis after infliximab in a patient with hepatitis B virus treated for an adult onset Still's disease. J Rheumatol 2003;30:1624-5.&lt;/p&gt;&lt;p&gt;Olivieri I., de Stefano G., Padula A. et al. Infliximab in a case of early adult-onset Still's disease. Clin Rheumatol 2003;22:369-70.&lt;/p&gt;&lt;p&gt;Serratrice J., Granel B., Disdier P. et al. Resolution with etanercept of nephrotic syndrome due to renal AA amyloidosis in adult Still's disease. Am J Med 2003;115:589-90.&lt;/p&gt;&lt;p&gt;Kumari R., Uppal S.S. Prolonged remission in adult-onset Still's disease with etanercept. Clin Rheumatol 2006;25:106-8.&lt;/p&gt;&lt;p&gt;Asherson R.A., Pascoe L. Adult onset Still's disease: response to Enbrel. Ann Rheum Dis 2002;61:859-60.&lt;/p&gt;&lt;p&gt;Benucci M., Li G.F., Del Rosso A. et al. Adalimumab (anti-TNF-alpha) therapy to improve the clinical course of adult-onset Still's disease: the first case report [letter]. Clin Exp Rheumatol 2005;23:733.&lt;/p&gt;&lt;p&gt;Haraoui B., Bourrelle D., Kaminska E. Anakinra in the treatmentof adult onset Still's disease. Ann Rheum Dis 2004;63(Suppl.):293-4.&lt;/p&gt;&lt;p&gt;Kotter I., Wacker A., Koch S. et al. Anakinra in patients with treatment-resistant adult-onset Still's disease: four case reports with serial cytokine measurements and a review of the literature. Semin Arthr Rheum 2007;37:189-97.&lt;/p&gt;&lt;p&gt;Kalliolias G.D., Georgiou P.E., Antonopoulos I.A. et al. Anakinra treatment in patients with adult-onset Still's disease is fast, effective, safe and steroid sparing: experience from an uncontrial. Ann Rheum Dis 2007;66:842-3.&lt;/p&gt;&lt;p&gt;Vasques Godinho F.M., Parreira Santos M.J., Canas da Silva J. Refractory adult onset Still's disease successfully treated with anakinra. Ann Rheum Dis 2005;64:647-8.&lt;/p&gt;&lt;p&gt;Rudinskaya A., Trock D.H. Successful treatment of a patient with refractory adultonset Still disease with anakinra. J Clin Rheumatol 2003;9:330-2.&lt;/p&gt;&lt;p&gt;Quartuccio L., De Vita S. Interleukin 1 receptor antagonist therapy-induced thrombocytopenia in adult onset Still's disease. J Rheumatol 2007;34:892-3.&lt;/p&gt;&lt;p&gt;Chu C., Hughes G., Karr N. et al. Interleukin-1 blockade is an effective treatment of adult onset Still's disease. Arthr Rheum 2005;52:4101.&lt;/p&gt;&lt;p&gt;Lequerre T., Quartier P., Rosellini D. et al. Interleukin-1 receptor antagonist (anakinra) treatment in patients with systemic-onset juvenile idiopathic arthritis or adult onset Still disease: preliminary experience in France. Ann Rheum Dis 2008;67:302-8.&lt;/p&gt;&lt;p&gt;Ahmadi-Simab K., Lamprecht P., Jankowiak C., Gross W.L. Successful treatment of refractory adult onset Still's disease with rituximab. Ann Rheum Dis 2006;65:1117-8.&lt;/p&gt;&lt;p&gt;Nakahara H., Mima T., Yoshio-Hoshino N. et al. A case report of a patient with refractory adult onset Still's disease who was successfully treated with tocilizumab over 6 years. Mod Rheumatol 2009;19:69-72.&lt;/p&gt;&lt;p&gt;De Bandt M., Saint-Marcouux B. Tocilizumab for multirefractory adult-onset Still's disease. Ann Rheum Dis 2009;68:153-4.&lt;/p&gt;&lt;p&gt;Priori R., Ceccarelli F., Baqrone F. et al. Clinical, biological and sonographic response to IL-1 blockade in adult-onset Still's disease. Clin Exp Rheumatol 2008;26:933-7.&lt;/p&gt;&lt;p&gt;Bartoloni E., Alunno A., Luccioli F. et al. Successful treatment of refractory adultonset Still's disease with anti-CD20 monoclonal antibody. Clin Exp Rheumatol 2009;27:888-9.&lt;/p&gt;&lt;p&gt;Appenzeller S., Castro G., Costallat L. et al. Adult-onset Still disease in southeast Brazil. J Clin Rheumatol 2005;11:76-80.&lt;/p&gt;&lt;p&gt;Arkfeld D.G. The potential utility of B cell-directed biologic therapy in autoimmune diseases. Rheumatol Int 2008;28:205-15.&lt;/p&gt;&lt;p&gt;Kong X.D., Xu D., Zhang W. et al. Clinical features and prognosis in adultonset still's disease: a study of 104 cases. Clin Rheumatol 2010;29:1015-9.&lt;/p&gt;&lt;p&gt;Franchini S., Dagna L., Salvo F. et al. Efficacy of traditional and biological agents in different clinical phenotypes of adultonset Still's disease. Arthr Rheum 2010, Apr 29 [Epub. ahead of print].&lt;/p&gt;&lt;p&gt;Quartuccio L., Maset M., De Vita S. Efficacy of abatacept in a refractory case of adult-onset Still's disease. Clin Exp Rheumatol 2010;28:265-7.&lt;/p&gt;&lt;p&gt;Ak O., Ozer S., Cag Y., Karagöz G. An adult onset Still's disease mimicking pneumonia. Rheumatol Int 2010, Apr 2 [Epub. ahead of print].&lt;/p&gt;&lt;p&gt;Муравьев Ю.В., Жуковская Г.Н., Лебедева В.В. О синдроме Стилла у взрослых. Ревматология 1991;1:37-40.&lt;/p&gt;&lt;p&gt;Carli L., Rizelli G.M.L., d'Ascanio A. et al. Adult onset Still'disease: analysis of a monocentric cohort. Ann Rheum Dis 2010;69(Suppl. 3):716.&lt;/p&gt;&lt;p&gt;Salvin S., Quartuccio L., Moroldo T. et al. Clinical characterization and treatment outcome in a monocentric cohort of 45 patients with adult onset Still's disease. Ann Rheum Dis 2010;69(Suppl. 3):710.&lt;/p&gt;&lt;p&gt;Perdan-Pirkmajer K., Praprotnik S., Tomsic M. A case of refractory adult-onset Still's disease successfully controlled with tocilizumab and a review of the literature. Clin Rheumatol 2010, Aug 24 [Epub. ahead of print].&lt;/p&gt;&lt;p&gt;Kobayashi M., Takahashi Y., Yamashita H. et al. Benefit and a possible risk of tocilizumab therapy for adult-onset Still's disease accompanied by macrophage-activation syndrome. Mod Rheumatol 2010, Aug 26 [Epub. ahead of print].&lt;/p&gt;&lt;p&gt;Sumida K., Ubara Y., Hoshino J. et al. Etanercept-refractory adult-onset Still's disease with thrombotic thrombocytopenic purpura successfully treated with tocilizumab. Clin Rheumatol 2010, Mar 12 [Epub. ahead of print].&lt;/p&gt;&lt;p&gt;Matsumoto K., Nagashima T., Takatori S. et al. Glucocorticoid and cyclosporine refractory adult onset Still's disease successfully treated with tocilizumab. Clin Rheumatol 2009;28:485-7.&lt;/p&gt;&lt;p&gt;Yoshimura M., Makiyama J., Koga T. et al. Successful treatment with tocilizumab in a patient with refractory adult-onset Still's disease (AOSD). Clin Exp Rheumatol 2010;28:141-2.&lt;/p&gt;&lt;p&gt;Puechal X., de Bandt M., Berthelot J.M. et al. Tocilizumab in refractory adult Still's disease. Arthr Care Res (Hoboken) 2010, Aug 25 [Epub. ahead of print].&lt;/p&gt;&lt;/div&gt;&lt;br /&gt;</mixed-citation><mixed-citation xml:lang="en">&lt;div&gt;&lt;p&gt;Международная статистическая классификация болезней и проблем, связанных со здоровьем;10-й пересмотр. Женева: ВОЗ, 1995.&lt;/p&gt;&lt;p&gt;Efthimiou P., Paik P.K., Bielory L. Diagnosis and management of adult onset Still's disease. Ann Rheum Dis 2006;65:564-72.&lt;/p&gt;&lt;p&gt;Bannatyne G.A., Wohlmann A.S. Rheumatoid Arthritis: Its clinical history, etiology and pathology. Lancet 1896;1:1120-5.&lt;/p&gt;&lt;p&gt;Still G.F. On a form of chronic joint disease in children. Med Chir Trans 1897;80:47-65.&lt;/p&gt;&lt;p&gt;Reimann H.A., de Bardinis C.T. Periodic cyclic neutropenia, an entity. Blood 1949;4:1109-16.&lt;/p&gt;&lt;p&gt;Wissler H. Uber eine besondere Form sepsisahnlicher krankheiten (subsepsishyperergica). Z Kinderheilkd 1964;94:1-23.&lt;/p&gt;&lt;p&gt;Hegglin R., Uehlinger E. Klinische Demonstrationen: Febris periodica hyperergica. Schweiz Med Wschr 1964;94:675-85.&lt;/p&gt;&lt;p&gt;Fanconi G. Uber einen Fall von Subsepsis allergica Wissler. Helv Paediatr Acta 1946;1:532-7.&lt;/p&gt;&lt;p&gt;Riolet J. Syndrome de Wissler-Fanconi. Rev Rhum Mal Osteartic 1964;31:388-97.&lt;/p&gt;&lt;p&gt;Larson E.B. Adult Still's disease - recognition of a clinical syndrome and recent experience. West J Med 1985;142:665-71.&lt;/p&gt;&lt;p&gt;Wissler H. Subsepsis allergica. Ergeb Inn Med Kinderheilkd 1965;23:202-20.&lt;/p&gt;&lt;p&gt;Bywaters E.G. Still's disease in the adult. Ann Rheum Dis 1971;30:121-33.&lt;/p&gt;&lt;p&gt;Bywaters E.G. Categorization in medicine: A survey of Still's disease. Ann Rheum Dis 1967;26:185-93.&lt;/p&gt;&lt;p&gt;Bujak J.S., Aptekar R.G., Decker J.L. et al. Juvenile rheumatoid arthritis in theadult presenting as fever of unknown origin. Medicine (Baltimore) 1973;52:431-44.&lt;/p&gt;&lt;p&gt;Fabricant M.S., Chander S.B., Friou G.J. Still's disease in adults: A cause of prolonged undiagnosed fever. JAMA 1973;225:273-5.&lt;/p&gt;&lt;p&gt;Caroit M., Mathieu M., Kahn M.F. et al. Maladie de Still de l'adulte et syndrome de Wissler-Fanconi. Rev Rhum Mal Osteartic 1973;40:1-8.&lt;/p&gt;&lt;p&gt;Calabro J.J., Marchesano J.M. Fever associated with juvenile rheumatoid arthritis. N Engl J Med 1967;276:1-18.&lt;/p&gt;&lt;p&gt;Isdaile I.C., Bywaters E.G. The rash in Still's disease. Quart J Med 1956;25:377-87.&lt;/p&gt;&lt;p&gt;Calabro J.J., Cruess R.L., Levinson J.E. et al. Juvenile rheumatoid arthritis. Patient Care 1977;11:70-116.&lt;/p&gt;&lt;p&gt;Elkon K.B., Hughes G.R., Bywaters E.G. et al. Adult onset Still's disease: Twenty-year follow-up and further studies of patients with active disease. Arthr Rheum 1982;25:647-53.&lt;/p&gt;&lt;p&gt;Medsger T.A., Christy W.C. Carpal arthritis with ankylosis in late-onset Still's disease. Arthr Rheum 1976;19:232-42.&lt;/p&gt;&lt;p&gt;Healey L.A., Willkens R.F. Tarsal arthritis with ankylosis in late-onset Still's disease. Arthr Rheum 1982;25:1254-6.&lt;/p&gt;&lt;p&gt;Jamieson T.W. Adult Still's disease complicated by cardiac tamponade. JAMA 1983;249:2065-6.&lt;/p&gt;&lt;p&gt;Tesser J.R., Pisko E.J., Hartz J.W. et al. Chronic liver disease and adult Still's disease. Arthr Rheum 1982;25:579-82.&lt;/p&gt;&lt;p&gt;Baker D.G., Schumacher H.R., Reginato A.J. Fifteen patients with adult onset Still's disease: Life-threatening liver failure in two (Abstr). Arthr Rheum 1979;22:590.&lt;/p&gt;&lt;p&gt;Masson C., Le Loët X., Liote F. et al. Adult Still's disease: part I. Manifestations and complications in sixty-five cases in France. Rev Rhum Engl Ed 1995;62:748-57.&lt;/p&gt;&lt;p&gt;Pelkonen P., Swanliung K., Siimes M.A. Ferritinemia as an indicator of systemic disease activity in children with systemic juvenile rheumatoid arthritis. Acta Paediatr Scand 1986;75:64-8.&lt;/p&gt;&lt;p&gt;Gonzalez-Hernandez T., Martin-Mola E., Femandez-Zamoeano A. et al. Serum ferritin can be useful for diagnosis in adult onset Still's disease. J Rheumatol 1989;16:412-3.&lt;/p&gt;&lt;p&gt;Fautrel B., Le Moel G., Saint-Marcoux B. et al. Diagnostic value of ferritin and glycosylated ferritin in adult onset Still's disease. J Rheumatol 2001;28:322-9.&lt;/p&gt;&lt;p&gt;Fautrel B. Ferritin levels in adult Still's disease: any sugar? J Bone Spine 2002;69:355-7.&lt;/p&gt;&lt;p&gt;Cush J.J. Adult-onset Still's disease. Bull Rheum Dis 2000;49:1-4.&lt;/p&gt;&lt;p&gt;Van Reeth C., Le Moel G., Lasne Y. et al. Serum ferritin and isoferritins are tools for diagnosis of active adult Still's dis ease. J Rheumatol 1994;21:890-5.&lt;/p&gt;&lt;p&gt;Akritidis N., Giannakakis I., Giouglis T. Ferritin levels and response to treatment in patients with adult Still's disease. J Rheumatol 1996;23:201-2.&lt;/p&gt;&lt;p&gt;Magadur-Joly G., Billaud E., Barrier J.H. et al. Epidemiology of adult Still's disease: estimate of the incidence by a retrospective study in west France. Ann Rheum Dis 1995;54:587-90.&lt;/p&gt;&lt;p&gt;Wakai K., Ohta A., Tamakoshi A. et al. Estimated prevalence and incidence of adult Still's disease: findings by anationwide epidemiological survey in Japan. J Epidemiol 1997;7:221-5.&lt;/p&gt;&lt;p&gt;Ohta A., Yamaguchi M., Tsunematsu T. et al. Adult Still's disease: a multicenter survey of Japanese patients. J Rheumatol 1990;17:1058-63.&lt;/p&gt;&lt;p&gt;Van de Putte L.B., Wouters J.M. Adultonset Still's disease. Bailliere's Clin Rheumatol 1991;5:263-75.&lt;/p&gt;&lt;p&gt;Wouters J.M., van de Putte L.B. Adultonset Still's disease; clinical and laboratory features, treatment and progress of 45 cases. Quart J Med 1986;61:1055-65.&lt;/p&gt;&lt;p&gt;Sampalis J.S., Medsger T.A., Fries J.F. et al. Risk factors for adult Still's disease. J Rheumatol 1996;23:2049-54.&lt;/p&gt;&lt;p&gt;Kontzias A., Efthimiou P. Adult-Onset Still's Disease Pathogenesis, Clinical Manifestations and Therapeutic Advances. Drugs 2008;68:319-37.&lt;/p&gt;&lt;p&gt;Hoshino T., Ohta A., Yang D. et al. Elevated serum interleukin 6, interferongamma, and tumor necrosis factor-alpha levels in patients with adult Still's disease. J Rheumatol 1998;25:396-8.&lt;/p&gt;&lt;p&gt;Ogata A., Kitano M., Yamanaka J. et al. Interleukin 18 and hepatocyte growth factor in fulminant hepatic failure of adult onset Still's disease. J Rheumatol 2003;30:1093-6.&lt;/p&gt;&lt;p&gt;Kotter I., Wacker A., Koch S. et al. Anakinra in patients with treatment-resistant adult-onset Still's disease: four case reports with serial cytokine measurements and a review of the literature. Semin Arthr Rheum 2007;37:189-97.&lt;/p&gt;&lt;p&gt;Jeon Y.K., Paik J.H., Park S.S. et al. Spectrum of lymph node pathology in adult onset Still's disease; analysis of 12 patients with one follow up biopsy. J Clin Pathol 2004;57:1052-6.&lt;/p&gt;&lt;p&gt;Jamin C., Morva A., Lemoine S. et al. Regulatory B lymphocytes in humans. A potential role in autoimmunity. Arthr Rheum 2008;58:1900-6.&lt;/p&gt;&lt;p&gt;Yamaguchi M., Ohta A., Tsunematsu T. et al. Preliminary criteria for classification of adult Still's disease. J Rheumatol 1992;19:424-30.&lt;/p&gt;&lt;p&gt;Cush J.J., Medsger T. Jr., Christy W.C. et al. Adult-onset Still's disease: clinical course and outcome. Arthr Rheum 1987;30:186-94.&lt;/p&gt;&lt;p&gt;Fautrel B., Zing E., Golmard J.L. et al. Proposal for a new set of classification criteria for adult-onset Still disease. Medicine (Baltimore) 2002;81:194-200.&lt;/p&gt;&lt;p&gt;Pouchot J., Sampalis J.S., Beaudet F. et al. Adult Still's disease: manifestations, disease course, and outcome in 62 patients. Medicine (Baltimore) 1991;70:118-36.&lt;/p&gt;&lt;p&gt;Evensen K.J., Nossent H.C. Epidemiology and outcome of adult onset Still's disease in northern Norway. Scand J Rheumatol 2006;35:48-51.&lt;/p&gt;&lt;p&gt;Pay S., Turkcapar N., Kalyoncu M. et al. A multicenter study of patients with adultonset Still's disease compared with systemic juvenile idiopathic arthritis. Clin Rheumatol 2006;25:639-44.&lt;/p&gt;&lt;p&gt;Mandl L., Esdaile J.M. Adult Still's disease. Up To Date. &amp;lt;http://www.uptodate.com/&amp;gt; (accessed 14 February 2006).&lt;/p&gt;&lt;p&gt;Kaplinsky N., Paas M., Frankl О. An adult form of juvenile rheumatoid arthritis. Arch Intern Med 1980;140:1073-4.&lt;/p&gt;&lt;p&gt;Khraishi M., Fam A.G. Treatment of fulminant adult Still's disease with intravenous pulse methylprednisolone therapy. J Rheumatol 1991;18:1088-90.&lt;/p&gt;&lt;p&gt;Bambery P., Thomas R.J., Malhotra H.S. et al. Adult onset Still's disease: clinical experience with 18 patients over 15 years in northern India. Ann Rheum Dis 1992;51:529-32.&lt;/p&gt;&lt;p&gt;Shojania K., Chalmers A., Rangno K. Cyclosporin A in thetreatment of adult Still's disease. J Rheumatol 1995;22:1391-2.&lt;/p&gt;&lt;p&gt;Cefle A. Leflunomide and azathioprine combination in refractory adult-onset Still's disease. Ann Pharmacother 2005;39:764-7.&lt;/p&gt;&lt;p&gt;Murakami K., Fujii T., Yukawa N. et al. Successful treatment of a patient with refractory adult Still's disease by tacrolimus. The Japan Rheum. Association. Modern Rheumatol 2007;17:167-70.&lt;/p&gt;&lt;p&gt;Mahmud T., Hughes G.R. Intravenous immunoglobulin in thetreatment of refractory adult Still's disease. J Rheumatol 1999;26:2067-8.&lt;/p&gt;&lt;p&gt;Vignes S., Wechsler B., Amoura Z. et al. Intravenous immunoglobulin in adult Still's disease refractory to non-steroidal antiinflammatory drugs. Clin Exp Rheumatol 1998;16:295-8.&lt;/p&gt;&lt;p&gt;Bennett A.N., Peterson P., Sangle S. et al. Adult onset Still's disease and collapsing glomerulopathy: successful treatment with intravenous immunoglobulins and mycophenolate mofetil. Rheumatology (Oxford) 2004;43:795-9.&lt;/p&gt;&lt;p&gt;Husni M.E., Maier A.L., Mease P.J. et al. Etanercept in the treatment of adult patients with Still's disease. Arthr Rheum 2002;46:1171-6.&lt;/p&gt;&lt;p&gt;Kuek A., Weerakoon A., Ahmed K. et al. Adult-onset Still's disease and myocarditis: successful treatment with intravenous immunoglobulin and maintenance of remission with etanercept. Rheumatology (Oxford) 2007;46:1043-4.&lt;/p&gt;&lt;p&gt;Cavagna L., Caporali R., Epis O. et al. Infliximab in the treatment of adult Still's disease refractory to conventional therapy. Clin Exp Rheumatol 2001;19:329-32.&lt;/p&gt;&lt;p&gt;Kokkinos A., Iliopoulos A., Greka P. et al. Successful treatment of refractory adultonset Still's disease with infliximab: a prospective, non-comparative series of four patients. Clin Rheumatol 2004;23:45-9.&lt;/p&gt;&lt;p&gt;Huffstutter J., Sienknecht C. Treatment of resistant adult Still's disease with infliximab: a report of 2 cases. J Clin Rheumatol 2004;10:218-21.&lt;/p&gt;&lt;p&gt;Bonilla Hernan M.G., Cobo Ibanez T., de Miguel Mendieta E. et al. Infliximab (anti-TNF-alpha) treatment in patients with adult Still's disease: experience in 2 cases [in Spanish]. Ann Med Interna 2004;21:23-6.&lt;/p&gt;&lt;p&gt;Caramaschi P., Biasi D., Carletto A. et al. A case of adult onset Still's disease treated with infliximab [letter]. Clin Exp Rheumatol 54. 54. 64&lt;/p&gt;&lt;p&gt;Fautrel B., Sibilia J., Mariette X. et al. Tumour necrosis factor alpha blocking agents in refractory adult Still's disease: an observational study of 20 cases. Ann Rheum Dis 2005;64:262-6.&lt;/p&gt;&lt;p&gt;Benucci M., Li G.F., Del Rosso A. et al. Adalimumab (anti-TNF-alpha) therapy to improve the clinical course of adult-onset Still's disease: the first case report [letter]. Clin Exp Rheum 2005;23:733.&lt;/p&gt;&lt;p&gt;Efthimiou P., Georgy S. Pathogenesis and management of adult onset Still's disease. Semin Arthr Rheum 2006;36:144-52.&lt;/p&gt;&lt;p&gt;Godinho F., Santos M.J., Canas Da Silva J. Refractory adult onset Still's disease successfully treated with anakinra. Ann Rheum Dis 2005;64:647-8.&lt;/p&gt;&lt;p&gt;Fitzgerald A.A., Leclercq S.A., Yan A. et al. Rapid responses to anakinra in patients with refractory adult-onset Still's disease. Arthr Rheum 2005;52:1794-803.&lt;/p&gt;&lt;p&gt;Iwamoto M., Nara H., Hirata D. et al. Humanized monoclonal anti-interleukin-6 receptor antibody for treatment of intractable adult-onset Still's disease. Arthr Rheum 2002;46:3388-9.&lt;/p&gt;&lt;p&gt;Kraetsch H.G., Antoni C., Kalden J.R. et al. Successful treatment of a small cohort of patients with adult onset of Still's disease with infliximab: first experiences. Ann Rheum Dis 2001;60(Suppl. 3):55-7.&lt;/p&gt;&lt;p&gt;Dechant C., Schauenberg P., Antoni C.E. et al. Long-term out come of TNF blockade in adult-onset Still's disease [in German]. Dtsch Med Wschr 2004;129:1308-12.&lt;/p&gt;&lt;p&gt;Dilhuydy M.S., Vatan R., Etienne G. et al. Prolonged efficacy of infliximab for refractory adult-onset Still's disease. Clin Exp Rheumatol 2005;23:121-2.&lt;/p&gt;&lt;p&gt;Michel M., Duvoux C., Hezode C. et al. Fulminant hepatitis after infliximab in a patient with hepatitis B virus treated for an adult onset Still's disease. J Rheumatol 2003;30:1624-5.&lt;/p&gt;&lt;p&gt;Olivieri I., de Stefano G., Padula A. et al. Infliximab in a case of early adult-onset Still's disease. Clin Rheumatol 2003;22:369-70.&lt;/p&gt;&lt;p&gt;Serratrice J., Granel B., Disdier P. et al. Resolution with etanercept of nephrotic syndrome due to renal AA amyloidosis in adult Still's disease. Am J Med 2003;115:589-90.&lt;/p&gt;&lt;p&gt;Kumari R., Uppal S.S. Prolonged remission in adult-onset Still's disease with etanercept. Clin Rheumatol 2006;25:106-8.&lt;/p&gt;&lt;p&gt;Asherson R.A., Pascoe L. Adult onset Still's disease: response to Enbrel. Ann Rheum Dis 2002;61:859-60.&lt;/p&gt;&lt;p&gt;Benucci M., Li G.F., Del Rosso A. et al. Adalimumab (anti-TNF-alpha) therapy to improve the clinical course of adult-onset Still's disease: the first case report [letter]. Clin Exp Rheumatol 2005;23:733.&lt;/p&gt;&lt;p&gt;Haraoui B., Bourrelle D., Kaminska E. Anakinra in the treatmentof adult onset Still's disease. Ann Rheum Dis 2004;63(Suppl.):293-4.&lt;/p&gt;&lt;p&gt;Kotter I., Wacker A., Koch S. et al. Anakinra in patients with treatment-resistant adult-onset Still's disease: four case reports with serial cytokine measurements and a review of the literature. Semin Arthr Rheum 2007;37:189-97.&lt;/p&gt;&lt;p&gt;Kalliolias G.D., Georgiou P.E., Antonopoulos I.A. et al. Anakinra treatment in patients with adult-onset Still's disease is fast, effective, safe and steroid sparing: experience from an uncontrial. Ann Rheum Dis 2007;66:842-3.&lt;/p&gt;&lt;p&gt;Vasques Godinho F.M., Parreira Santos M.J., Canas da Silva J. Refractory adult onset Still's disease successfully treated with anakinra. Ann Rheum Dis 2005;64:647-8.&lt;/p&gt;&lt;p&gt;Rudinskaya A., Trock D.H. Successful treatment of a patient with refractory adultonset Still disease with anakinra. J Clin Rheumatol 2003;9:330-2.&lt;/p&gt;&lt;p&gt;Quartuccio L., De Vita S. Interleukin 1 receptor antagonist therapy-induced thrombocytopenia in adult onset Still's disease. J Rheumatol 2007;34:892-3.&lt;/p&gt;&lt;p&gt;Chu C., Hughes G., Karr N. et al. Interleukin-1 blockade is an effective treatment of adult onset Still's disease. Arthr Rheum 2005;52:4101.&lt;/p&gt;&lt;p&gt;Lequerre T., Quartier P., Rosellini D. et al. Interleukin-1 receptor antagonist (anakinra) treatment in patients with systemic-onset juvenile idiopathic arthritis or adult onset Still disease: preliminary experience in France. Ann Rheum Dis 2008;67:302-8.&lt;/p&gt;&lt;p&gt;Ahmadi-Simab K., Lamprecht P., Jankowiak C., Gross W.L. Successful treatment of refractory adult onset Still's disease with rituximab. Ann Rheum Dis 2006;65:1117-8.&lt;/p&gt;&lt;p&gt;Nakahara H., Mima T., Yoshio-Hoshino N. et al. A case report of a patient with refractory adult onset Still's disease who was successfully treated with tocilizumab over 6 years. Mod Rheumatol 2009;19:69-72.&lt;/p&gt;&lt;p&gt;De Bandt M., Saint-Marcouux B. Tocilizumab for multirefractory adult-onset Still's disease. Ann Rheum Dis 2009;68:153-4.&lt;/p&gt;&lt;p&gt;Priori R., Ceccarelli F., Baqrone F. et al. Clinical, biological and sonographic response to IL-1 blockade in adult-onset Still's disease. Clin Exp Rheumatol 2008;26:933-7.&lt;/p&gt;&lt;p&gt;Bartoloni E., Alunno A., Luccioli F. et al. Successful treatment of refractory adultonset Still's disease with anti-CD20 monoclonal antibody. Clin Exp Rheumatol 2009;27:888-9.&lt;/p&gt;&lt;p&gt;Appenzeller S., Castro G., Costallat L. et al. Adult-onset Still disease in southeast Brazil. J Clin Rheumatol 2005;11:76-80.&lt;/p&gt;&lt;p&gt;Arkfeld D.G. The potential utility of B cell-directed biologic therapy in autoimmune diseases. Rheumatol Int 2008;28:205-15.&lt;/p&gt;&lt;p&gt;Kong X.D., Xu D., Zhang W. et al. Clinical features and prognosis in adultonset still's disease: a study of 104 cases. Clin Rheumatol 2010;29:1015-9.&lt;/p&gt;&lt;p&gt;Franchini S., Dagna L., Salvo F. et al. Efficacy of traditional and biological agents in different clinical phenotypes of adultonset Still's disease. Arthr Rheum 2010, Apr 29 [Epub. ahead of print].&lt;/p&gt;&lt;p&gt;Quartuccio L., Maset M., De Vita S. Efficacy of abatacept in a refractory case of adult-onset Still's disease. Clin Exp Rheumatol 2010;28:265-7.&lt;/p&gt;&lt;p&gt;Ak O., Ozer S., Cag Y., Karagöz G. An adult onset Still's disease mimicking pneumonia. Rheumatol Int 2010, Apr 2 [Epub. ahead of print].&lt;/p&gt;&lt;p&gt;Муравьев Ю.В., Жуковская Г.Н., Лебедева В.В. О синдроме Стилла у взрослых. Ревматология 1991;1:37-40.&lt;/p&gt;&lt;p&gt;Carli L., Rizelli G.M.L., d'Ascanio A. et al. Adult onset Still'disease: analysis of a monocentric cohort. Ann Rheum Dis 2010;69(Suppl. 3):716.&lt;/p&gt;&lt;p&gt;Salvin S., Quartuccio L., Moroldo T. et al. Clinical characterization and treatment outcome in a monocentric cohort of 45 patients with adult onset Still's disease. Ann Rheum Dis 2010;69(Suppl. 3):710.&lt;/p&gt;&lt;p&gt;Perdan-Pirkmajer K., Praprotnik S., Tomsic M. A case of refractory adult-onset Still's disease successfully controlled with tocilizumab and a review of the literature. Clin Rheumatol 2010, Aug 24 [Epub. ahead of print].&lt;/p&gt;&lt;p&gt;Kobayashi M., Takahashi Y., Yamashita H. et al. Benefit and a possible risk of tocilizumab therapy for adult-onset Still's disease accompanied by macrophage-activation syndrome. Mod Rheumatol 2010, Aug 26 [Epub. ahead of print].&lt;/p&gt;&lt;p&gt;Sumida K., Ubara Y., Hoshino J. et al. Etanercept-refractory adult-onset Still's disease with thrombotic thrombocytopenic purpura successfully treated with tocilizumab. Clin Rheumatol 2010, Mar 12 [Epub. ahead of print].&lt;/p&gt;&lt;p&gt;Matsumoto K., Nagashima T., Takatori S. et al. Glucocorticoid and cyclosporine refractory adult onset Still's disease successfully treated with tocilizumab. Clin Rheumatol 2009;28:485-7.&lt;/p&gt;&lt;p&gt;Yoshimura M., Makiyama J., Koga T. et al. Successful treatment with tocilizumab in a patient with refractory adult-onset Still's disease (AOSD). Clin Exp Rheumatol 2010;28:141-2.&lt;/p&gt;&lt;p&gt;Puechal X., de Bandt M., Berthelot J.M. et al. Tocilizumab in refractory adult Still's disease. Arthr Care Res (Hoboken) 2010, Aug 25 [Epub. ahead of print].&lt;/p&gt;&lt;/div&gt;&lt;br /&gt;</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
