rspНаучно-практическая ревматологияRheumatology Science and Practice1995-44841995-4492IMA-PRESS, LLC10.14412/1995-4484-2005-622rsp-760Research ArticleСтатьиArticlesНовые данные о глюкозамине сульфатеNew data about glucosamin sulphateArwenfeldMArwenfeldM-200515082005434№4 (2005)7680Copyright © Arwenfeld M., 20052005Arwenfeld M.Arwenfeld M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://rsp.mediar-press.net/rsp/article/view/760References<div><p>Felson D.T., Zhand Y. An update on the epidemiology of knee and hip osteoarthritis with a view to prevention. Arthr.Reum., 1998,41. 1343-1355</p><p>Oliveira S.A., Felson D.T., ReedJ.l. Incidence of symptomatic hand, hip and knee osteoarthritis among patients in a health maintenance organization. Arthr.Reum.,1995, 38. 1134-1141</p><p>Pendleton A., Arden N. Dougados M. et al. EULAR recommendations for the management of knee osteoarthritis: report of a task of the Standing Committee for International Clinical Studies Including Therapeutic Trials (ESCISIT). Ann. Rcum.Dis., 2000,59,936-944</p><p>Guccione A.A., Felson D.T., Anderson J.J. et al. The effects of specific medical conditions on the functional limitations of elders in the Framingham Study. Am.J.Public Health, 1994,84, 351-358</p><p>Setnikar I., Rovati L.C., Absorplion, distribution, metabolism and excretion of glucosamine sulfate: a review. Arzneimittelforschung, 2001,51, 699-725</p><p>Noyszewski E.A., Wroblewski K., Dodge G.R. et al. Preferential incorporation of glucosamine into the galactosamine moieties of chondroilin sulfates in articular cartilage explanls. Arthr.Reum., 2001, 44, 1089-1095</p><p>Bassleer C., Rovati L.C., Franchimont P. Glucosamine sulfate stimulates proteoglycan production in human chondrocytes in vitro. Osteoarthr. Cartil., 1998, 6, 427-434</p><p>Piperno М., Reboul P., Helio Le Graverand M.P. et al. Glucosamine sulfate modulates dysregulater activities of human osteoarthritis chondrocytes in vitro. Osteoarthr. Cartil., 2000. 8. 207-212</p><p>Dodge G.R., Jimenez SA. Glucosamine sulfate modulates the levels ofaggrecan and matrix meiallopteinase-3 synthesized by cultured humanosteoarthritis articular chondrocytes, Osteoarthr. Cartil., 2003, 11, 424-432</p><p>Yaron I., Shirasi I., Judovich R., Yaron M. Glucosamine sulfate inhibits nitric oxide and stromelusin production in cartilage cultures and reverses IL-1 inhibition of osteoarthritis articular cartilage sintetasis. Ann. Reum.Dis., 2001,60, suppl., 50</p><p>Lardo R., Alvares-Soria M.A., Diez-Ortego J. et al. Glucosamine ingibits IL-l(i- induced NF(?B frticulation et al. in human osteoarthritic chondrocytes. Osteoarthr. Cartil., 2003,11, 290-298</p><p>Sethikarl. Cereda R., Pacini M.A., Revel L, Antireactive properties of glucosamine sulfate. Arzneimittelforschung, 1991,41,157-161.</p><p>Hoffer L.J., Kaplan L.N., Hamadeh M.J. et al. Sulfate could mediate the therapeutic effect of glucosamine sulfate. Metabolism, 2001, 50, 767-770.</p><p>McAlindon T.E. U Valley M.P., Gulin J.P., Felson D.T. Glucosamine and chondroilin for treatment of osteoarthritis: a ssystematic quality assessment and tneta-analysis. JAMA, 2000, 283, 1469-1475</p><p>Egger М., Davey Smith G., Scheneider М., MinderC. Bias in meta analysis detected bi a simple, graphical test. BMJ, 1997,315,629-634</p><p>Sterne J.A., Egger М., Smith G.D. Systematic reviews in health care: investigating and dealing with publicacion and other biases in meta analysis. BMJ, 2001., 323, 101-105</p><p>Towheend T.E. Anastassiades T.P., Shea B. et al. Glucosamine therapy for treating osteoarthritis (Cochrane Review). ln:The Cochrane Library, Issue 2, 2001. Oxford: Update Software</p><p>Lequesne M.G., Mery C., Samson М., Gerard P. Indexes of severity for osteoarthritis of the hip knee. V&lidation-value in comparison with other assessment tests. Scand. J. Reumotol., 1987,65, suppl., 85-89</p><p>RichyF., Bruyere O., Ethgen et al. Structural and symptomatic efficacy of glucosamine and chondroilin in knee osteoarthritis. A comprehensive Meta-analysis. Arch, Int. Med., 2003,163,1514-1522</p><p>Reginster J.Y., Deroisy R., Rovati L.C. et al. Long-term effects of glucosamine sulfate on osteoarthritis progression: a randomized, placebo controlled clinical trial. Lancet, 2001,357,251-256</p><p>Pavelka K., Gatterova J.OIejarova M. et al. Glucosamine sulfate use and delay of progression of knee osteoarthritis: 3-year, randomized, placebo-controlled, duble-blind study. Arch. Int. Med.,2002., 162,2113-2123</p><p>McAlindon T.E. Glucosamine for osteoarthritis: dawn of a new era? Lancet, 2001,357,247-248</p><p>Bruyere O.Honore A., Rovati L.C. et al. Rndililogic features poorly predict clinical outcomes in knee osteoarthritis. Scand. J. Reumotol., 2002,31,13-16</p><p>Bruyere 0.,Honore A., Ethgen O. et al. Correlation between radiographic severity of knee osteoarthritis and future disease progression. Results from a 3-year, prospective, placebo-controlled, study evaluating the of glucosamine sulfate. Osteoarthr. Cartil., 2003, 12, 1-5</p><p>Pavelka K., Rovati L.C., Gatterova J. et al. Pain relief is not a confounder in joint space narrowing assessment of full extension knee radiographs. Osteoarthr. Cartil., 2002, 10 (suppl. A), S 16-17</p><p>Baron A.D., Zhu J.S, Zhu J.H. et al. Glucosamine induces insulin resistance in vivo by affecting GLUT 4 translocacion in skeletal muscle. Implications for glucose toxicity. J. Clin. Invest., 1995,96, 2792-2801</p><p>MonauniT., Zenti M.G., Cretti A. et al. Effects of glucosamine infusion on insulin secretion and insulin action in humans. Diabetes, 2000,49,926-935</p><p>Pouwels M.J., Jacobs J.R., Span P.N. et al. Short-term glucosamine infusion does not affect insulin sensitivity in humans. J. Clin. Endocrinol. Metab., 2001, 86, 2099-2103.</p><p>Rovati L.C., Annefeld М., Giacovelli G. et al. Glucosamine in osteoarthritis. Lancet, 1999,354,1640</p><p>Scroggie D.A., Albright A., Harris M. The effect of glu- cosamine-chondroitin supplementation on glycosylated hemoglobin levels in patiens with type2 diabetes mellitus. A placebo- controlled, duble-blinded, randomized clinical trial. Arch.Int.Med., 2003, 163, 1587-1590</p></div><br /><div><p>Felson D.T., Zhand Y. An update on the epidemiology of knee and hip osteoarthritis with a view to prevention. Arthr.Reum., 1998,41. 1343-1355</p><p>Oliveira S.A., Felson D.T., ReedJ.l. Incidence of symptomatic hand, hip and knee osteoarthritis among patients in a health maintenance organization. Arthr.Reum.,1995, 38. 1134-1141</p><p>Pendleton A., Arden N. Dougados M. et al. EULAR recommendations for the management of knee osteoarthritis: report of a task of the Standing Committee for International Clinical Studies Including Therapeutic Trials (ESCISIT). Ann. Rcum.Dis., 2000,59,936-944</p><p>Guccione A.A., Felson D.T., Anderson J.J. et al. The effects of specific medical conditions on the functional limitations of elders in the Framingham Study. Am.J.Public Health, 1994,84, 351-358</p><p>Setnikar I., Rovati L.C., Absorplion, distribution, metabolism and excretion of glucosamine sulfate: a review. Arzneimittelforschung, 2001,51, 699-725</p><p>Noyszewski E.A., Wroblewski K., Dodge G.R. et al. Preferential incorporation of glucosamine into the galactosamine moieties of chondroilin sulfates in articular cartilage explanls. Arthr.Reum., 2001, 44, 1089-1095</p><p>Bassleer C., Rovati L.C., Franchimont P. Glucosamine sulfate stimulates proteoglycan production in human chondrocytes in vitro. Osteoarthr. Cartil., 1998, 6, 427-434</p><p>Piperno М., Reboul P., Helio Le Graverand M.P. et al. Glucosamine sulfate modulates dysregulater activities of human osteoarthritis chondrocytes in vitro. Osteoarthr. Cartil., 2000. 8. 207-212</p><p>Dodge G.R., Jimenez SA. Glucosamine sulfate modulates the levels ofaggrecan and matrix meiallopteinase-3 synthesized by cultured humanosteoarthritis articular chondrocytes, Osteoarthr. Cartil., 2003, 11, 424-432</p><p>Yaron I., Shirasi I., Judovich R., Yaron M. Glucosamine sulfate inhibits nitric oxide and stromelusin production in cartilage cultures and reverses IL-1 inhibition of osteoarthritis articular cartilage sintetasis. Ann. Reum.Dis., 2001,60, suppl., 50</p><p>Lardo R., Alvares-Soria M.A., Diez-Ortego J. et al. Glucosamine ingibits IL-l(i- induced NF(?B frticulation et al. in human osteoarthritic chondrocytes. Osteoarthr. Cartil., 2003,11, 290-298</p><p>Sethikarl. Cereda R., Pacini M.A., Revel L, Antireactive properties of glucosamine sulfate. Arzneimittelforschung, 1991,41,157-161.</p><p>Hoffer L.J., Kaplan L.N., Hamadeh M.J. et al. Sulfate could mediate the therapeutic effect of glucosamine sulfate. Metabolism, 2001, 50, 767-770.</p><p>McAlindon T.E. U Valley M.P., Gulin J.P., Felson D.T. Glucosamine and chondroilin for treatment of osteoarthritis: a ssystematic quality assessment and tneta-analysis. JAMA, 2000, 283, 1469-1475</p><p>Egger М., Davey Smith G., Scheneider М., MinderC. Bias in meta analysis detected bi a simple, graphical test. BMJ, 1997,315,629-634</p><p>Sterne J.A., Egger М., Smith G.D. Systematic reviews in health care: investigating and dealing with publicacion and other biases in meta analysis. BMJ, 2001., 323, 101-105</p><p>Towheend T.E. Anastassiades T.P., Shea B. et al. Glucosamine therapy for treating osteoarthritis (Cochrane Review). ln:The Cochrane Library, Issue 2, 2001. Oxford: Update Software</p><p>Lequesne M.G., Mery C., Samson М., Gerard P. Indexes of severity for osteoarthritis of the hip knee. V&lidation-value in comparison with other assessment tests. Scand. J. Reumotol., 1987,65, suppl., 85-89</p><p>RichyF., Bruyere O., Ethgen et al. Structural and symptomatic efficacy of glucosamine and chondroilin in knee osteoarthritis. A comprehensive Meta-analysis. Arch, Int. Med., 2003,163,1514-1522</p><p>Reginster J.Y., Deroisy R., Rovati L.C. et al. Long-term effects of glucosamine sulfate on osteoarthritis progression: a randomized, placebo controlled clinical trial. Lancet, 2001,357,251-256</p><p>Pavelka K., Gatterova J.OIejarova M. et al. Glucosamine sulfate use and delay of progression of knee osteoarthritis: 3-year, randomized, placebo-controlled, duble-blind study. Arch. Int. Med.,2002., 162,2113-2123</p><p>McAlindon T.E. Glucosamine for osteoarthritis: dawn of a new era? Lancet, 2001,357,247-248</p><p>Bruyere O.Honore A., Rovati L.C. et al. Rndililogic features poorly predict clinical outcomes in knee osteoarthritis. Scand. J. Reumotol., 2002,31,13-16</p><p>Bruyere 0.,Honore A., Ethgen O. et al. Correlation between radiographic severity of knee osteoarthritis and future disease progression. Results from a 3-year, prospective, placebo-controlled, study evaluating the of glucosamine sulfate. Osteoarthr. Cartil., 2003, 12, 1-5</p><p>Pavelka K., Rovati L.C., Gatterova J. et al. Pain relief is not a confounder in joint space narrowing assessment of full extension knee radiographs. Osteoarthr. Cartil., 2002, 10 (suppl. A), S 16-17</p><p>Baron A.D., Zhu J.S, Zhu J.H. et al. Glucosamine induces insulin resistance in vivo by affecting GLUT 4 translocacion in skeletal muscle. Implications for glucose toxicity. J. Clin. Invest., 1995,96, 2792-2801</p><p>MonauniT., Zenti M.G., Cretti A. et al. Effects of glucosamine infusion on insulin secretion and insulin action in humans. Diabetes, 2000,49,926-935</p><p>Pouwels M.J., Jacobs J.R., Span P.N. et al. Short-term glucosamine infusion does not affect insulin sensitivity in humans. J. Clin. Endocrinol. Metab., 2001, 86, 2099-2103.</p><p>Rovati L.C., Annefeld М., Giacovelli G. et al. Glucosamine in osteoarthritis. Lancet, 1999,354,1640</p><p>Scroggie D.A., Albright A., Harris M. The effect of glu- cosamine-chondroitin supplementation on glycosylated hemoglobin levels in patiens with type2 diabetes mellitus. A placebo- controlled, duble-blinded, randomized clinical trial. Arch.Int.Med., 2003, 163, 1587-1590</p></div><br />
The authors declare that there are no conflicts of interest present.