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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rsp</journal-id><journal-title-group><journal-title xml:lang="ru">Научно-практическая ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Rheumatology Science and Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-4484</issn><issn pub-type="epub">1995-4492</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1995-4484-2007-685</article-id><article-id custom-type="elpub" pub-id-type="custom">rsp-822</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Перспективы применения Артрозилена (кетопрофена лизиновая соль) в ревматологической практике</article-title><trans-title-group xml:lang="en"><trans-title>Perspectives of Artrosilene (ketoprofen lysine salt) administration in rheumatologic practice</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Балабанова</surname><given-names>Римма Михайловна</given-names></name><name name-style="western" xml:lang="en"><surname>Balabanova</surname><given-names>R M</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Насонова</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Nasonova</surname><given-names>V A</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Kaptaeva</surname><given-names>A K</given-names></name><name name-style="western" xml:lang="en"><surname>Kaptaeva</surname><given-names>A K</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib></contrib-group><pub-date pub-type="collection"><year>2007</year></pub-date><pub-date pub-type="epub"><day>15</day><month>06</month><year>2007</year></pub-date><volume>45</volume><issue>3</issue><issue-title>№3 (2007)</issue-title><fpage>28</fpage><lpage>33</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Балабанова Р.М., Насонова В.А., Kaptaeva A.K., 2007</copyright-statement><copyright-year>2007</copyright-year><copyright-holder xml:lang="ru">Балабанова Р.М., Насонова В.А., Kaptaeva A.K.</copyright-holder><copyright-holder xml:lang="en">Balabanova R.M., Nasonova V.A., Kaptaeva A.K.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://rsp.mediar-press.net/rsp/article/view/822">https://rsp.mediar-press.net/rsp/article/view/822</self-uri></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">&lt;div&gt;&lt;p&gt;Bannwarth В., SchaeverbekeT., DehaisJ. Calcitonin and osteoporosis. Fact and fiction. Rev. Rheum. Engl. Ed., 1995, 62(1), 3-6.&lt;/p&gt;&lt;p&gt;Patrono C., Patrignani P., Garcia Rodriguez L.A. Cyclooxygenase-selective inhibition of prostanoid formation: transducing biochemical selectivity into clinical read-outs. J. Clin. Invest., 2001, 108(1), 713.&lt;/p&gt;&lt;p&gt;feys E.M. 20 years’ experience with ketoprofen. Scand. J. Rheum. Suppl., 1991, 90, 1-44.&lt;/p&gt;&lt;p&gt;Braga P.C. Ketoprofen: i.c.v. injection and electrophysiological aspects of antinociceptive effect. Eur. J. Pharmacol., 1990, 10,184(2-3), 273280.&lt;/p&gt;&lt;p&gt;Bizzarri C., Pagliei S., Brandolini L. et al. Selective inhibition of interleukin-8-induced neutrophil chemotaxis by ketoprofen isomers. Biochem. Pharmacol., 2001, 1,61(11), 1429-1437.&lt;/p&gt;&lt;p&gt;Walker J.S., Scheather-Rehd R.B. NSAIDs in rheumatoid arthritis and osteoarthritis. Arthr. Rheum., 1987, 11, 1944-1954.&lt;/p&gt;&lt;p&gt;Singh G., Terry R., Ramey D.R. et al. Comparative gastrointestinal toxicity of NSAIDs. Arthr. Rheum., 1997,40(8), 115-118.&lt;/p&gt;&lt;p&gt;BrewerE.J.,GianniniE.H.,BaumJ.etal. Ketoprofen (Orudis) in the treatment of juvenile rheumatoid arthritis. A segment I study. J. Rheumatol., 1982, 9(1), 144-148.&lt;/p&gt;&lt;p&gt;Arone S. Long term study of ketoprofen SR in elderly patients. Scand. J. Rheumatol. Suppl., 1989, 83, 15-19.&lt;/p&gt;&lt;p&gt;Чичасова H.B., Имаметдинова Г.Р., Иголкина E.B. Кетонал (кетопрофен)в практике ревматологаи терапевта. РМЖ, 2003, 23, 1288-1290.&lt;/p&gt;&lt;p&gt;Pietrogrande V., Leonardi М., Marinoni Е.С. Impiego profilatticoе terapeutico degli antiflogistici nella terapia della malattia artrosica. Ortop. Traum. Oggi., 1982, 11, 2, 223-231.&lt;/p&gt;&lt;p&gt;Guidoboni R. Uncontrolled clinical trial on gastric side effects of slow-release ketoprofen lysine. Curr. Therap. Res., 1983, 34-5, 839-843.&lt;/p&gt;&lt;p&gt;D’arienzo М., Pennisi М., Zanolo G., Borsa M. Ketoprofen lysine: Ketoprofen serum levels and analgesic activity. Drugs Exp. Clin. Res., 1984, 10,2,363-366.&lt;/p&gt;&lt;p&gt;Trotta F., Dovigo L., Pellegrini P. et al. Pharmacokinetic study of slow release ketoprofen lysine in patients with rheumatoid arthritis and osteoarthritis. Eur. Review Med. Pharmacol. Sci., 1984, VI, 583-588.&lt;/p&gt;&lt;p&gt;Torn G., Cecchettin М., Bellometti S. et al. Analgesic effect and beta-endorphin and substance P levels in plasma after short-term administration ofa ketoprofen lysine salt or acetylsalicylic acid in patients with osteoarthritis. Curr. Therap. Res., 1995, 56, 1, 62-69.&lt;/p&gt;&lt;p&gt;Daffonchio L., Novellini R., Bertuglia S. Protective effect of ketoprofen lysine salt on interleukin-lbeta and bradykinin induced inflammatory changes in hamster cheek pouch microcirculation. Inflamm. Res., 2002, 51(5), 223-228.&lt;/p&gt;&lt;p&gt;Daffonchio L., Rossoni G., Clavenna G. et al. Protective activity of ketoprofen lysine salt against the pulmonary effects induced by bradykinin in guinea-pigs. Inflamm. Res., 1996, 45(5), 259-264.&lt;/p&gt;&lt;p&gt;Fiorentino S., Melillo G., Fedele G. et al. Ketoprofen lysine salt inhibits disuse-induced osteopenia ina new non-traumatic immobilization model in the rat. Pharmacol. Res., 1996, 33(4-5), 277-281.&lt;/p&gt;&lt;p&gt;Balzanelli B, de Lorenzi C. Efficacy and tolerability 80 mg granulated ketoprofen lysine salt in posttraumatic orodental pain: double blind vs placebo study. Minerva Stomatol., 1996, 45(1-2), 53-59.&lt;/p&gt;&lt;p&gt;Borsa М., Malandrino S., Ronchi C. et al. Pharmacologic and pharmacokinetic activity of ketoprofen lysine salt for topical administration. Farmaco [Prat]., 1983, 38(2), 87-96.&lt;/p&gt;&lt;p&gt;Buggiani P. Le mesotherapia con ketoprofeni sale di lisina nella artrosi del ginocchio. Rivista Italiana. Ortop. Traumat., 1986, 26, 2, 193-200.&lt;/p&gt;&lt;p&gt;Maridati C., Sala U. et al. Ketoprofen sale dilisina gel in traumatologiae ortopedia artrosilene. Dompe Farmacentici, Milano, Ortop. Traum. Oggi., 1982, 22, 25-35.&lt;/p&gt;&lt;p&gt;Berardi R., Piga A., Pulita F. et al. Effective prevention of 5-fluorouracil-induced superficial phlebitis by ketoprofen lysine salt gel. Am. J. Med., 2003, 1, 115(5), 415-417.&lt;/p&gt;&lt;p&gt;Rapisardi M.I. Rapporto rischio-beneficio del trayyamento con ketoprofene sale di lisina in ortopedia, fisiatriae reumatologia. Gazz. Med. Ital., 1990, 149, 125-135.&lt;/p&gt;&lt;p&gt;Memeo A., Cosentina R. Ketoprofen lysine treatment of painful manifestations of spinal osteoarthrosis. Clin Ter., 1988, 31, 126 (2), 119122.&lt;/p&gt;&lt;p&gt;Chevallard M., Mele G., Borsa M. et al. Effectiveness and tolerability of ketoprofen lysine, oncea day, in patients with rheumatic disorders. Drugs Exp. Clin. Res., 1987, 13 (5), 293-296.&lt;/p&gt;&lt;p&gt;Camelli V.E., Mei V.A., Cera R. et al. Effects of various dosage of ketoprofen salt suppositories in acute inflammatory disease in infants (3-36 month old) and children (3-13 year old). Minerva Pediatr., 1995, 47 (5), 199-205. '&lt;/p&gt;&lt;p&gt;Messed A., Busoni P., Noccioli B. et al. Analgesic efficacy and tolerability of ketoprofen lysine salt vs paracetamol in common paediatric surgery. A randomized, single-blind, parallel, multicentre trial. Paediatr. Anaesth., 2003, 13 (7), 574-578.&lt;/p&gt;&lt;p&gt;Corda R., Camelli V. Use of the NSAID ketoprofen lysine salt in glucose-6-phosphate dehydrogenase (G6PD) deficiency in inflammatory disease in children. Pediatr. Med. Chin, 1996, 18(4), 391-394.&lt;/p&gt;&lt;/div&gt;&lt;br /&gt;</mixed-citation><mixed-citation xml:lang="en">&lt;div&gt;&lt;p&gt;Bannwarth В., SchaeverbekeT., DehaisJ. Calcitonin and osteoporosis. Fact and fiction. Rev. Rheum. Engl. Ed., 1995, 62(1), 3-6.&lt;/p&gt;&lt;p&gt;Patrono C., Patrignani P., Garcia Rodriguez L.A. Cyclooxygenase-selective inhibition of prostanoid formation: transducing biochemical selectivity into clinical read-outs. J. Clin. Invest., 2001, 108(1), 713.&lt;/p&gt;&lt;p&gt;feys E.M. 20 years’ experience with ketoprofen. Scand. J. Rheum. Suppl., 1991, 90, 1-44.&lt;/p&gt;&lt;p&gt;Braga P.C. Ketoprofen: i.c.v. injection and electrophysiological aspects of antinociceptive effect. Eur. J. Pharmacol., 1990, 10,184(2-3), 273280.&lt;/p&gt;&lt;p&gt;Bizzarri C., Pagliei S., Brandolini L. et al. Selective inhibition of interleukin-8-induced neutrophil chemotaxis by ketoprofen isomers. Biochem. Pharmacol., 2001, 1,61(11), 1429-1437.&lt;/p&gt;&lt;p&gt;Walker J.S., Scheather-Rehd R.B. NSAIDs in rheumatoid arthritis and osteoarthritis. Arthr. Rheum., 1987, 11, 1944-1954.&lt;/p&gt;&lt;p&gt;Singh G., Terry R., Ramey D.R. et al. Comparative gastrointestinal toxicity of NSAIDs. Arthr. Rheum., 1997,40(8), 115-118.&lt;/p&gt;&lt;p&gt;BrewerE.J.,GianniniE.H.,BaumJ.etal. Ketoprofen (Orudis) in the treatment of juvenile rheumatoid arthritis. A segment I study. J. Rheumatol., 1982, 9(1), 144-148.&lt;/p&gt;&lt;p&gt;Arone S. Long term study of ketoprofen SR in elderly patients. Scand. J. Rheumatol. Suppl., 1989, 83, 15-19.&lt;/p&gt;&lt;p&gt;Чичасова H.B., Имаметдинова Г.Р., Иголкина E.B. Кетонал (кетопрофен)в практике ревматологаи терапевта. РМЖ, 2003, 23, 1288-1290.&lt;/p&gt;&lt;p&gt;Pietrogrande V., Leonardi М., Marinoni Е.С. Impiego profilatticoе terapeutico degli antiflogistici nella terapia della malattia artrosica. Ortop. Traum. Oggi., 1982, 11, 2, 223-231.&lt;/p&gt;&lt;p&gt;Guidoboni R. Uncontrolled clinical trial on gastric side effects of slow-release ketoprofen lysine. Curr. Therap. Res., 1983, 34-5, 839-843.&lt;/p&gt;&lt;p&gt;D’arienzo М., Pennisi М., Zanolo G., Borsa M. Ketoprofen lysine: Ketoprofen serum levels and analgesic activity. Drugs Exp. Clin. Res., 1984, 10,2,363-366.&lt;/p&gt;&lt;p&gt;Trotta F., Dovigo L., Pellegrini P. et al. Pharmacokinetic study of slow release ketoprofen lysine in patients with rheumatoid arthritis and osteoarthritis. Eur. Review Med. Pharmacol. Sci., 1984, VI, 583-588.&lt;/p&gt;&lt;p&gt;Torn G., Cecchettin М., Bellometti S. et al. Analgesic effect and beta-endorphin and substance P levels in plasma after short-term administration ofa ketoprofen lysine salt or acetylsalicylic acid in patients with osteoarthritis. Curr. Therap. Res., 1995, 56, 1, 62-69.&lt;/p&gt;&lt;p&gt;Daffonchio L., Novellini R., Bertuglia S. Protective effect of ketoprofen lysine salt on interleukin-lbeta and bradykinin induced inflammatory changes in hamster cheek pouch microcirculation. Inflamm. Res., 2002, 51(5), 223-228.&lt;/p&gt;&lt;p&gt;Daffonchio L., Rossoni G., Clavenna G. et al. Protective activity of ketoprofen lysine salt against the pulmonary effects induced by bradykinin in guinea-pigs. Inflamm. Res., 1996, 45(5), 259-264.&lt;/p&gt;&lt;p&gt;Fiorentino S., Melillo G., Fedele G. et al. Ketoprofen lysine salt inhibits disuse-induced osteopenia ina new non-traumatic immobilization model in the rat. Pharmacol. Res., 1996, 33(4-5), 277-281.&lt;/p&gt;&lt;p&gt;Balzanelli B, de Lorenzi C. Efficacy and tolerability 80 mg granulated ketoprofen lysine salt in posttraumatic orodental pain: double blind vs placebo study. Minerva Stomatol., 1996, 45(1-2), 53-59.&lt;/p&gt;&lt;p&gt;Borsa М., Malandrino S., Ronchi C. et al. Pharmacologic and pharmacokinetic activity of ketoprofen lysine salt for topical administration. Farmaco [Prat]., 1983, 38(2), 87-96.&lt;/p&gt;&lt;p&gt;Buggiani P. Le mesotherapia con ketoprofeni sale di lisina nella artrosi del ginocchio. Rivista Italiana. Ortop. Traumat., 1986, 26, 2, 193-200.&lt;/p&gt;&lt;p&gt;Maridati C., Sala U. et al. Ketoprofen sale dilisina gel in traumatologiae ortopedia artrosilene. Dompe Farmacentici, Milano, Ortop. Traum. Oggi., 1982, 22, 25-35.&lt;/p&gt;&lt;p&gt;Berardi R., Piga A., Pulita F. et al. Effective prevention of 5-fluorouracil-induced superficial phlebitis by ketoprofen lysine salt gel. Am. J. Med., 2003, 1, 115(5), 415-417.&lt;/p&gt;&lt;p&gt;Rapisardi M.I. Rapporto rischio-beneficio del trayyamento con ketoprofene sale di lisina in ortopedia, fisiatriae reumatologia. Gazz. Med. Ital., 1990, 149, 125-135.&lt;/p&gt;&lt;p&gt;Memeo A., Cosentina R. Ketoprofen lysine treatment of painful manifestations of spinal osteoarthrosis. Clin Ter., 1988, 31, 126 (2), 119122.&lt;/p&gt;&lt;p&gt;Chevallard M., Mele G., Borsa M. et al. Effectiveness and tolerability of ketoprofen lysine, oncea day, in patients with rheumatic disorders. Drugs Exp. Clin. Res., 1987, 13 (5), 293-296.&lt;/p&gt;&lt;p&gt;Camelli V.E., Mei V.A., Cera R. et al. Effects of various dosage of ketoprofen salt suppositories in acute inflammatory disease in infants (3-36 month old) and children (3-13 year old). Minerva Pediatr., 1995, 47 (5), 199-205. '&lt;/p&gt;&lt;p&gt;Messed A., Busoni P., Noccioli B. et al. Analgesic efficacy and tolerability of ketoprofen lysine salt vs paracetamol in common paediatric surgery. A randomized, single-blind, parallel, multicentre trial. Paediatr. Anaesth., 2003, 13 (7), 574-578.&lt;/p&gt;&lt;p&gt;Corda R., Camelli V. Use of the NSAID ketoprofen lysine salt in glucose-6-phosphate dehydrogenase (G6PD) deficiency in inflammatory disease in children. Pediatr. Med. Chin, 1996, 18(4), 391-394.&lt;/p&gt;&lt;/div&gt;&lt;br /&gt;</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
