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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rsp</journal-id><journal-title-group><journal-title xml:lang="ru">Научно-практическая ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Rheumatology Science and Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-4484</issn><issn pub-type="epub">1995-4492</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1995-4484-2007-695</article-id><article-id custom-type="elpub" pub-id-type="custom">rsp-832</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Ревмоортопедия: актуальные вопросы дооперационного период</article-title><trans-title-group xml:lang="en"><trans-title>Rheumoorthopedy: actual questions of preoperational period</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Павлов</surname><given-names>В. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Pavlov</surname><given-names>V P</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib></contrib-group><pub-date pub-type="collection"><year>2007</year></pub-date><pub-date pub-type="epub"><day>15</day><month>06</month><year>2007</year></pub-date><volume>45</volume><issue>3</issue><issue-title>№3 (2007)</issue-title><fpage>96</fpage><lpage>104</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Павлов В.П., 2007</copyright-statement><copyright-year>2007</copyright-year><copyright-holder xml:lang="ru">Павлов В.П.</copyright-holder><copyright-holder xml:lang="en">Pavlov V.P.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://rsp.mediar-press.net/rsp/article/view/832">https://rsp.mediar-press.net/rsp/article/view/832</self-uri></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">&lt;div&gt;&lt;p&gt;Копенкин С.С., Моисеев С.В. Профилактика венозных тромбоэмболических осложнений при эндопротезировании суставов.Хирургия. Прилож. кжурн. Concilium Medicum, 2006,1,26-29.&lt;/p&gt;&lt;p&gt;Павлов В.П. Хирургическое лечение инфекционного неспецифического (ревматоидного) полиартрита. М., Медицина, 1977&lt;/p&gt;&lt;p&gt;Adrizzone В., Bollan S.,Mannzionna G. et al. Comparisonbetween methothrexate andazathioprine in the treatment chronic active Crohn”s disease:a randomaised investigator-blind study. Dig. Liver Dis.,2003,35,619-627.&lt;/p&gt;&lt;p&gt;Arumguam S., Nimmanit S., Enquist J.F. The effect of immunosupression of wound healing. Surg. Ginecol. Obstet., 1971, 133, 72-73.&lt;/p&gt;&lt;p&gt;Barnes P.J. Mechanisms of action of glucocorticoids in asthma. Am. J. Resp.Crit. Care Med., 1996, 154 (suppl), 21-27.&lt;/p&gt;&lt;p&gt;Bibbo C., Goldberg Infectious and healing complications after elective orthopedic foot and ankle surgery during tumor necrosis factor an inhibition therapy. Foot Ancle Int.,2004,25,331-333&lt;/p&gt;&lt;p&gt;Bridges S.L., Lopez-Mendez A,Han K.H. et al. Should methothrexate be discontinued before elective orthopedic surgery in patients with rheumatoid arthritis. J. Rheumatol., 1991, 18, 984-988.&lt;/p&gt;&lt;p&gt;Busty A.J., Pharm D., HooperJ.B. et al. Effects of Perioperative Antiinflammatory and Immunomodulating Therapy on Surgical Wound Healing. Posted 12/02q 2005 hup: www medscape. Com / viem wasticle / 5116912 / src = search&lt;/p&gt;&lt;p&gt;Caristedt C.A., Madsen K., WredmarkT. The influense of indomethacin on collagen synthesis during tendon healing in the rabbit. Prostogland.,1986, 32, 353-358.&lt;/p&gt;&lt;p&gt;Carpenter M.T.,West S.G.,VogelgesandS.A., Casey J. Postoperative joint infections in rheumatoid arthritis patients on methotrexate therapy.Orthopedics, 1996,19,207-210.&lt;/p&gt;&lt;p&gt;Colombel J.F., Loftus E.V.,Tremaine W.J. et al. Early postoperative complications are not increased in patients with Cron”s disease treated perioperatively with infliximab or immunosupressive therapy. Am.J. Gastroenterol., 2004,99,878883.&lt;/p&gt;&lt;p&gt;Dimitrievic М., Bartlett R.R. Leflunomide,a novel immunomodulating drug, inhibits homotypic adhesion of mononuclear cells in rheumatoid arthritis.Transplant. Ргос., 1996, 28, 3086-3087.&lt;/p&gt;&lt;p&gt;Dong Y.L.,Declan F., Yan T.Z. et al. Effect of ibuprofen on the inflammatory response to surgical wounds. J.Trauma, 1993, 35, 340 -343.&lt;/p&gt;&lt;p&gt;Escalante A., Beardmore T.D. Risk factors for early wound complications after orthopedic surgery for rheumatoid arthritis. J. Rheumatol., 1995, 22, 1844 1857.&lt;/p&gt;&lt;p&gt;Fox R.L., Herrmann M.L., Costacis G.F. et al. Mechanism of action for lefuluomide in rheumatoid arthritis. Clin. Immunol.,1999, 93, 198 208.&lt;/p&gt;&lt;p&gt;Greets W., Pineo E.G., Heit J. et al. Prevention of venous thromboembolism. The seventh ACCP Conf. of Antithrombolitic anad Thrombolitic Therapy. Chest, 2004, 126,338S 400S&lt;/p&gt;&lt;p&gt;Grenan D.M., Gray J.,London J.,Fear S. Methothrexate andearlypostoperative complications in patients with rheumatoid arthritis undergoing elective orthopedic surgery.Ann. Rheum.Dis., 2001, 60,214-217.&lt;/p&gt;&lt;p&gt;Hamilton L., Vojnovic A., Bakhle Y. et al. The antiinflammatory drug leflunomade inhibits in vitro and in vivo the activity of COX —2 more potently then induction of COX — 2 in NOS. (abstr) Proc. Br.Pharmacol Soc., 1996, 18, s.51&lt;/p&gt;&lt;p&gt;Hanauer S.B.,Present D.H. The state of the art in the management of inflammatory bowel disease. Rev.Gastroenterol. Distord., 2003, 3, 81-92&lt;/p&gt;&lt;p&gt;Kasdan M.L., June 1. Postoperative results of rheumatoid arthritis patients on methotrexate at the time of reconstructive surgery of the hand. Orthopedics, 1993, 16, 1233 1235.&lt;/p&gt;&lt;p&gt;Lelcuk S., Merhav A., Klaussmer J.M. et al. Prostacyclin (PGL 2) and thromboxane (TX) A 2: mediators wound healing. Isr. Med. Sci., 1987, 23, 841 -843.&lt;/p&gt;&lt;p&gt;Lipsky P.E., Ziff M. Inhibition of human helper T cell funcion in vitro by pencillamin and CuSO 4. J. Clin. Invest., 1980, 65, 1069 1076.&lt;/p&gt;&lt;p&gt;Mowat A.G.,Baum J. Chemotaxis of polymorphonuclear leucocytes from patients with rheumatoid arthritis. J.Clin. Invest., 1971, 50, 2541 -2549&lt;/p&gt;&lt;p&gt;Nicitinskaja O.A., Benevolenskaja L.I. The effect of alfacalcidol on bone mineral density and bone turnover in postmenopausal osteoporosis. Abstr. 9-th Asia Pacific League of Assos Rheum.Congr. APZar, 2000, Beipin, China, P275.&lt;/p&gt;&lt;p&gt;Oxlund H.,Fodesttam I., Viidik A. The influence of cortisol of wound healing of the skin and distant connective tissue response. Surg. Gynecol.Obstet., 1971, 148, 876880.&lt;/p&gt;&lt;p&gt;Phillips K., Arffa R.,Citron C. et al. Effect of prednisolon and medroxyprogesterone on corneal wound healing , ulceration and neovascularization. Arch. Ophthalmol., 1983,101, 640 -643.&lt;/p&gt;&lt;p&gt;Rechmann K., Fairbanks L.D.,Carrey E.A. et al. Leflunomade inhibits pirimidine de novo synthesis in mitogen stimulated T-limphocytes from healthy humans. J.Biol.Chem.,1998, 273, 21, 682-691.&lt;/p&gt;&lt;p&gt;van Riel, Smolen J.S., Emery P. et al. Leflunomide:a manageable safety profile. J. Rheumatol., 2004, 31 (suppl. 71), 21-24.&lt;/p&gt;&lt;p&gt;Sany J.,Anaya J.M.,Canvas F. et al. Influence of methotrexate on the frequency of postoperative infectious complications in patiemts with rheumatoid arthritis. J.Rheumatol., 1993, 20, 1129 1132.&lt;/p&gt;&lt;p&gt;Schwibert L.M.,Bech L.A., Stellato C. et al. Glucocorticoid inhibition of cytokine productcion: relevance to antiallergic actions. J. Allergy Clin. Immunol., 1996, 97, 143,152.&lt;/p&gt;&lt;p&gt;Jain A., Witbrunk М.,Ball C. et al. Influence of steroids and meththrexate on wound complications after elective rheumatoid hand and wrist surgery. J.Hand Surg. (Am.), 2002, 27 A, 449 455.&lt;/p&gt;&lt;p&gt;Jones M.K.,Wang H., Peskar В. M. Inhibition of angiogenesis by nonsteroidal antiinflammatory drugs insight into mechanisms and implications for cancer growth und ulser healing. Natur. Med., 1999, 5, 1418-1423.&lt;/p&gt;&lt;/div&gt;&lt;br /&gt;</mixed-citation><mixed-citation xml:lang="en">&lt;div&gt;&lt;p&gt;Копенкин С.С., Моисеев С.В. Профилактика венозных тромбоэмболических осложнений при эндопротезировании суставов.Хирургия. Прилож. кжурн. Concilium Medicum, 2006,1,26-29.&lt;/p&gt;&lt;p&gt;Павлов В.П. Хирургическое лечение инфекционного неспецифического (ревматоидного) полиартрита. М., Медицина, 1977&lt;/p&gt;&lt;p&gt;Adrizzone В., Bollan S.,Mannzionna G. et al. Comparisonbetween methothrexate andazathioprine in the treatment chronic active Crohn”s disease:a randomaised investigator-blind study. Dig. Liver Dis.,2003,35,619-627.&lt;/p&gt;&lt;p&gt;Arumguam S., Nimmanit S., Enquist J.F. The effect of immunosupression of wound healing. Surg. Ginecol. Obstet., 1971, 133, 72-73.&lt;/p&gt;&lt;p&gt;Barnes P.J. Mechanisms of action of glucocorticoids in asthma. Am. J. Resp.Crit. Care Med., 1996, 154 (suppl), 21-27.&lt;/p&gt;&lt;p&gt;Bibbo C., Goldberg Infectious and healing complications after elective orthopedic foot and ankle surgery during tumor necrosis factor an inhibition therapy. Foot Ancle Int.,2004,25,331-333&lt;/p&gt;&lt;p&gt;Bridges S.L., Lopez-Mendez A,Han K.H. et al. Should methothrexate be discontinued before elective orthopedic surgery in patients with rheumatoid arthritis. J. Rheumatol., 1991, 18, 984-988.&lt;/p&gt;&lt;p&gt;Busty A.J., Pharm D., HooperJ.B. et al. Effects of Perioperative Antiinflammatory and Immunomodulating Therapy on Surgical Wound Healing. Posted 12/02q 2005 hup: www medscape. Com / viem wasticle / 5116912 / src = search&lt;/p&gt;&lt;p&gt;Caristedt C.A., Madsen K., WredmarkT. The influense of indomethacin on collagen synthesis during tendon healing in the rabbit. Prostogland.,1986, 32, 353-358.&lt;/p&gt;&lt;p&gt;Carpenter M.T.,West S.G.,VogelgesandS.A., Casey J. Postoperative joint infections in rheumatoid arthritis patients on methotrexate therapy.Orthopedics, 1996,19,207-210.&lt;/p&gt;&lt;p&gt;Colombel J.F., Loftus E.V.,Tremaine W.J. et al. Early postoperative complications are not increased in patients with Cron”s disease treated perioperatively with infliximab or immunosupressive therapy. Am.J. Gastroenterol., 2004,99,878883.&lt;/p&gt;&lt;p&gt;Dimitrievic М., Bartlett R.R. Leflunomide,a novel immunomodulating drug, inhibits homotypic adhesion of mononuclear cells in rheumatoid arthritis.Transplant. Ргос., 1996, 28, 3086-3087.&lt;/p&gt;&lt;p&gt;Dong Y.L.,Declan F., Yan T.Z. et al. Effect of ibuprofen on the inflammatory response to surgical wounds. J.Trauma, 1993, 35, 340 -343.&lt;/p&gt;&lt;p&gt;Escalante A., Beardmore T.D. Risk factors for early wound complications after orthopedic surgery for rheumatoid arthritis. J. Rheumatol., 1995, 22, 1844 1857.&lt;/p&gt;&lt;p&gt;Fox R.L., Herrmann M.L., Costacis G.F. et al. Mechanism of action for lefuluomide in rheumatoid arthritis. Clin. Immunol.,1999, 93, 198 208.&lt;/p&gt;&lt;p&gt;Greets W., Pineo E.G., Heit J. et al. Prevention of venous thromboembolism. The seventh ACCP Conf. of Antithrombolitic anad Thrombolitic Therapy. Chest, 2004, 126,338S 400S&lt;/p&gt;&lt;p&gt;Grenan D.M., Gray J.,London J.,Fear S. Methothrexate andearlypostoperative complications in patients with rheumatoid arthritis undergoing elective orthopedic surgery.Ann. Rheum.Dis., 2001, 60,214-217.&lt;/p&gt;&lt;p&gt;Hamilton L., Vojnovic A., Bakhle Y. et al. The antiinflammatory drug leflunomade inhibits in vitro and in vivo the activity of COX —2 more potently then induction of COX — 2 in NOS. (abstr) Proc. Br.Pharmacol Soc., 1996, 18, s.51&lt;/p&gt;&lt;p&gt;Hanauer S.B.,Present D.H. The state of the art in the management of inflammatory bowel disease. Rev.Gastroenterol. Distord., 2003, 3, 81-92&lt;/p&gt;&lt;p&gt;Kasdan M.L., June 1. Postoperative results of rheumatoid arthritis patients on methotrexate at the time of reconstructive surgery of the hand. Orthopedics, 1993, 16, 1233 1235.&lt;/p&gt;&lt;p&gt;Lelcuk S., Merhav A., Klaussmer J.M. et al. Prostacyclin (PGL 2) and thromboxane (TX) A 2: mediators wound healing. Isr. Med. Sci., 1987, 23, 841 -843.&lt;/p&gt;&lt;p&gt;Lipsky P.E., Ziff M. Inhibition of human helper T cell funcion in vitro by pencillamin and CuSO 4. J. Clin. Invest., 1980, 65, 1069 1076.&lt;/p&gt;&lt;p&gt;Mowat A.G.,Baum J. Chemotaxis of polymorphonuclear leucocytes from patients with rheumatoid arthritis. J.Clin. Invest., 1971, 50, 2541 -2549&lt;/p&gt;&lt;p&gt;Nicitinskaja O.A., Benevolenskaja L.I. The effect of alfacalcidol on bone mineral density and bone turnover in postmenopausal osteoporosis. Abstr. 9-th Asia Pacific League of Assos Rheum.Congr. APZar, 2000, Beipin, China, P275.&lt;/p&gt;&lt;p&gt;Oxlund H.,Fodesttam I., Viidik A. The influence of cortisol of wound healing of the skin and distant connective tissue response. Surg. Gynecol.Obstet., 1971, 148, 876880.&lt;/p&gt;&lt;p&gt;Phillips K., Arffa R.,Citron C. et al. Effect of prednisolon and medroxyprogesterone on corneal wound healing , ulceration and neovascularization. Arch. Ophthalmol., 1983,101, 640 -643.&lt;/p&gt;&lt;p&gt;Rechmann K., Fairbanks L.D.,Carrey E.A. et al. Leflunomade inhibits pirimidine de novo synthesis in mitogen stimulated T-limphocytes from healthy humans. J.Biol.Chem.,1998, 273, 21, 682-691.&lt;/p&gt;&lt;p&gt;van Riel, Smolen J.S., Emery P. et al. Leflunomide:a manageable safety profile. J. Rheumatol., 2004, 31 (suppl. 71), 21-24.&lt;/p&gt;&lt;p&gt;Sany J.,Anaya J.M.,Canvas F. et al. Influence of methotrexate on the frequency of postoperative infectious complications in patiemts with rheumatoid arthritis. J.Rheumatol., 1993, 20, 1129 1132.&lt;/p&gt;&lt;p&gt;Schwibert L.M.,Bech L.A., Stellato C. et al. Glucocorticoid inhibition of cytokine productcion: relevance to antiallergic actions. J. Allergy Clin. Immunol., 1996, 97, 143,152.&lt;/p&gt;&lt;p&gt;Jain A., Witbrunk М.,Ball C. et al. Influence of steroids and meththrexate on wound complications after elective rheumatoid hand and wrist surgery. J.Hand Surg. (Am.), 2002, 27 A, 449 455.&lt;/p&gt;&lt;p&gt;Jones M.K.,Wang H., Peskar В. M. Inhibition of angiogenesis by nonsteroidal antiinflammatory drugs insight into mechanisms and implications for cancer growth und ulser healing. Natur. Med., 1999, 5, 1418-1423.&lt;/p&gt;&lt;/div&gt;&lt;br /&gt;</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
