rspНаучно-практическая ревматологияRheumatology Science and Practice1995-44841995-4492IMA-PRESS, LLC10.14412/1995-4484-2012-710rsp-847Research ArticleСтатьиArticlesСравнение трех методов лучевой диагностики пирофосфатной артропатииComparison of three radiodiagnostic techniques for pyrophosphate arthropathyKudayevaFatima MagomedovnaKudayevaFatima MagomedovnaFatima.kudaeva@gmail.comБарсковаВ. Г.BarskovaV G-СмирновА. В.SmirnovA V-БожьеваЛ. А.BozhyevaL A-ОсипянцР. А.OsipyantsR A-201215062012503№3 (2012)5559Copyright © Kudayeva F.M., Барскова В.Г., Смирнов А.В., Божьева Л.А., Осипянц Р.А., 20122012Kudayeva F.M., Барскова В.Г., Смирнов А.В., Божьева Л.А., Осипянц Р.А.Kudayeva F.M., Barskova V.G., Smirnov A.V., Bozhyeva L.A., Osipyants R.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://rsp.mediar-press.net/rsp/article/view/847

Пирофосфатная артропатия (ПФА) - заболевание, являющееся результатом образования и депонирования кристаллов пирофосфата кальция в суставном хряще и развивающимся в связи с этим воспалением иммунного характера. Для постановки диагноза необходимо обнаружение характерных кристаллов пирофосфата кальция в синовиальной жидкости, полученной из сустава, и признаков кальцификации хряща, или хондрокальциноза, видимого на стандартных рентгенограммах. В статье рассматриваются причины затруднений в визуализации хондрокальциноза при рентгенографии коленных суставов, сравнивается значимость трех методов лучевой диагностики хондрокальциноза как одного из важных критериев при постановке диагноза ПФА.

Pyrophosphate arthropathy (PPA) is a disease that arises due to the formation and deposition of calcium pyrophosphate crystals within the articular cartilage and thereby develops into immune inflammation. Its diagnosis requires the detection of characteristic calcium pyrophosphate crystals in the synovial fluid from the affected joint, as well as the signs of cartilage calcification or chondrocalcinosis visible on conventional X-ray films. The paper considers reasons why it is difficult to visualize chondrocalcinosis by knee joint radiography and compares the importance of three techniques for the radiodiagnosis of chondrocalcinosis as one of the important criteria for diagnosing PPA.

пирофосфатная артропатияхондрокальцинозрентгенографияультразвуковое исследованиекомпьютерная томография суставовpyrophosphate arthropathychondrocalcinosisradiographyultrasound studycomputed tomography of jointsReferences<div><p>Hollander J.L., Jessar R.A., McCarty D.J. Synovianalysis: an aid in arthritis diagnosis. Bull Rheum Dis 1961;12:263-4.</p><p>Zhang W., Doherty M., Bardin T. et al. European League Against Rheumatism recommendations for calcium pyrophosphate deposi tion. Part I: terminology and diagnosis. Ann Rheum Dis 2011;70:563-70.</p><p>Doherty M., Dieppe P. Rheumatic disease clinics of North America. Clinical Aspects of Calcium Pyrophosphate Dihydrate Crystal Deposition. Cryst Depos Dis 1988;14(2):395-414.</p><p>Zhang W., Neame R., Doherty S., Doherty M. Relative risk of knee chondrocalcinosis in siblings of index cases with pyrophosphate arthropathy. Ann Rheum Dis 2004;63:969-73.</p><p>Utsinger P.D., Resnick D., Zvaifler N. Wrist arthropathy in calcium pyrophosphate dihydrate deposition disease. Arthr Rheum 1975;18:485-91.</p><p>Lothrenoo W., Sukitawut W. Calcium pyrophosphate dihydrate crystal deposition: a clinical and laboratory analysis of 91 Thai patients. J Med Assoc Thai 1999;82:569-76.</p><p>Martinez-Sanchis A., Pascual E. Intracellular and extracellular CPPD crystals are a regular feature in synovial fluid from uninflamed joints of patients with CPPD related arthropathy. Ann Rheum Dis 1999;58:582-4.</p><p>Genant H.K. Roentgenographic aspects of calcium pyrophosphat dihydrate crystal deposition disease (pseudogout). Arthr Rheum 1976;19:307-28.</p><p>Backhaus M., Burmester G.-R., Gerber T. et al. Guidelines for musculoskeletal ultrasound in rheumatology. Ann Rheum Dis 2001;60:641-9.</p><p>Filippou G., Frediani B., Gallo A. et al. A “new” technique for the diagnosis of chondrocalcinosis of the knee: sensitivity and specificity of high-frequency ultrasonography. Ann Rheum Dis 2007;66:1126-8.</p><p>Frediani B., Filippou G., Falsetti P. et al. Diagnosis of calcium pyrophosphate dihydrate crystal deposition disease: ultrasonographic criteria proposed. Ann Rheum Dis 2005;64:638-40.</p><p>Gerster J.C., Landry M., Dufresne L., Meuwly J.Y. Imaging of tophaceous gout: computed tomography provides specific images compared with magnetic resonance imaging and ultrasonography. Ann Rheum Dis 2002;61:52-4.</p><p>Scutellari P.N., Galeotti R., Leprotti S. et al. The crowned dens syndrome. Evaluation with CT imaging. Radiol Med 2007;112(2):195-207.</p><p>Salaffi F., Carotti M., Guglielmi G. et al. The crowned dens syndrome as a cause of neck pain: clinical and computed tomography study in patients with calcium pyrophosphate dihydrate deposition disease. Clin Exp Rheumatol 2008;26(6):1040-6.</p><p>Meng J., Guo C., Luo H. et al. A case of destructive calcium pyrophosphate dihydrate crystal deposition disease of the temporomandibular joint: a diagnostic challenge. Int J Oral Maxillofac Surg 2011;40:1431-7.</p><p>Doherty M., Dieppe P. Crystal deposition disease in the elderly. Clin Rheum Dis 1986;12:97-116.</p><p>Doherty M., Hamilton E., Henderson J. et al. Familial chondrocalcinosis due to calcium pyrophosphate dihydrate crystal deposition in English families. Br J Rheumatol 1991;30:10-5.</p><p>Neame R.L., Carr A.J., Muir K. et al. UK community prevalence of knee chondrocalcinosis: evidence that correlation with osteoarthritis is through a shared association with osteophyte. Ann Rheum Dis 2003;62:513-8.</p><p>Salaffi F., De Angelis R., Grassi W. Prevalence of musculoskeletal conditions in an Italian population sample: results of a regional community-based study. I. The MAPPING study. Clin Exp Rheumatol 2005;23:819-28.</p><p>Wilkins E., Dieppe P., Maddison P. et al. Osteoarthritis and articular chondrocalcinosis in the elderly. Ann Rheum Dis 1983;42:280-4.</p><p>Felson D.T., Anderson J.J., Naimark A. et al. The prevalence of chondrocalcinosis in the elderly and its association with knee osteoarthritis: the Framingham study. J Rheumatol 1989;16:1241-5.</p><p>Ramonda R., Musacchio E., Perissinotto E. et al. Prevalence of chondrocalcinosis in Italian subjects from northeastern Italy. The Pro.V.A. study. Clin Exp Rheumatol 2009;27(6):981-4.</p><p>McCarty D.J. Calcium pyrophosphate dihydrate deposition disease-1975. Arthr Rheum 1976;19(Suppl. 85):275-85.</p><p>Pascual E., Sivera F., Tekstra J., Jacobs W.G. Crystal arthropaties and septic arthritis. EULAR Compendium 2009;132-48.</p><p>Brown A.K., Wakefield R.J., Schmidt W.A. Imaging. EULAR Compendium 2009;651-68.</p></div><br /><div><p>Hollander J.L., Jessar R.A., McCarty D.J. Synovianalysis: an aid in arthritis diagnosis. Bull Rheum Dis 1961;12:263-4.</p><p>Zhang W., Doherty M., Bardin T. et al. European League Against Rheumatism recommendations for calcium pyrophosphate deposi tion. Part I: terminology and diagnosis. Ann Rheum Dis 2011;70:563-70.</p><p>Doherty M., Dieppe P. Rheumatic disease clinics of North America. Clinical Aspects of Calcium Pyrophosphate Dihydrate Crystal Deposition. Cryst Depos Dis 1988;14(2):395-414.</p><p>Zhang W., Neame R., Doherty S., Doherty M. Relative risk of knee chondrocalcinosis in siblings of index cases with pyrophosphate arthropathy. Ann Rheum Dis 2004;63:969-73.</p><p>Utsinger P.D., Resnick D., Zvaifler N. Wrist arthropathy in calcium pyrophosphate dihydrate deposition disease. Arthr Rheum 1975;18:485-91.</p><p>Lothrenoo W., Sukitawut W. Calcium pyrophosphate dihydrate crystal deposition: a clinical and laboratory analysis of 91 Thai patients. J Med Assoc Thai 1999;82:569-76.</p><p>Martinez-Sanchis A., Pascual E. Intracellular and extracellular CPPD crystals are a regular feature in synovial fluid from uninflamed joints of patients with CPPD related arthropathy. Ann Rheum Dis 1999;58:582-4.</p><p>Genant H.K. Roentgenographic aspects of calcium pyrophosphat dihydrate crystal deposition disease (pseudogout). Arthr Rheum 1976;19:307-28.</p><p>Backhaus M., Burmester G.-R., Gerber T. et al. Guidelines for musculoskeletal ultrasound in rheumatology. Ann Rheum Dis 2001;60:641-9.</p><p>Filippou G., Frediani B., Gallo A. et al. A “new” technique for the diagnosis of chondrocalcinosis of the knee: sensitivity and specificity of high-frequency ultrasonography. Ann Rheum Dis 2007;66:1126-8.</p><p>Frediani B., Filippou G., Falsetti P. et al. Diagnosis of calcium pyrophosphate dihydrate crystal deposition disease: ultrasonographic criteria proposed. Ann Rheum Dis 2005;64:638-40.</p><p>Gerster J.C., Landry M., Dufresne L., Meuwly J.Y. Imaging of tophaceous gout: computed tomography provides specific images compared with magnetic resonance imaging and ultrasonography. Ann Rheum Dis 2002;61:52-4.</p><p>Scutellari P.N., Galeotti R., Leprotti S. et al. The crowned dens syndrome. Evaluation with CT imaging. Radiol Med 2007;112(2):195-207.</p><p>Salaffi F., Carotti M., Guglielmi G. et al. The crowned dens syndrome as a cause of neck pain: clinical and computed tomography study in patients with calcium pyrophosphate dihydrate deposition disease. Clin Exp Rheumatol 2008;26(6):1040-6.</p><p>Meng J., Guo C., Luo H. et al. A case of destructive calcium pyrophosphate dihydrate crystal deposition disease of the temporomandibular joint: a diagnostic challenge. Int J Oral Maxillofac Surg 2011;40:1431-7.</p><p>Doherty M., Dieppe P. Crystal deposition disease in the elderly. Clin Rheum Dis 1986;12:97-116.</p><p>Doherty M., Hamilton E., Henderson J. et al. Familial chondrocalcinosis due to calcium pyrophosphate dihydrate crystal deposition in English families. Br J Rheumatol 1991;30:10-5.</p><p>Neame R.L., Carr A.J., Muir K. et al. UK community prevalence of knee chondrocalcinosis: evidence that correlation with osteoarthritis is through a shared association with osteophyte. Ann Rheum Dis 2003;62:513-8.</p><p>Salaffi F., De Angelis R., Grassi W. Prevalence of musculoskeletal conditions in an Italian population sample: results of a regional community-based study. I. The MAPPING study. Clin Exp Rheumatol 2005;23:819-28.</p><p>Wilkins E., Dieppe P., Maddison P. et al. Osteoarthritis and articular chondrocalcinosis in the elderly. Ann Rheum Dis 1983;42:280-4.</p><p>Felson D.T., Anderson J.J., Naimark A. et al. The prevalence of chondrocalcinosis in the elderly and its association with knee osteoarthritis: the Framingham study. J Rheumatol 1989;16:1241-5.</p><p>Ramonda R., Musacchio E., Perissinotto E. et al. Prevalence of chondrocalcinosis in Italian subjects from northeastern Italy. The Pro.V.A. study. Clin Exp Rheumatol 2009;27(6):981-4.</p><p>McCarty D.J. Calcium pyrophosphate dihydrate deposition disease-1975. Arthr Rheum 1976;19(Suppl. 85):275-85.</p><p>Pascual E., Sivera F., Tekstra J., Jacobs W.G. Crystal arthropaties and septic arthritis. EULAR Compendium 2009;132-48.</p><p>Brown A.K., Wakefield R.J., Schmidt W.A. Imaging. EULAR Compendium 2009;651-68.</p></div><br />

The authors declare that there are no conflicts of interest present.