rspНаучно-практическая ревматологияRheumatology Science and Practice1995-44841995-4492IMA-PRESS, LLC10.14412/1995-4484-2012-715rsp-852Research ArticleСтатьиArticlesМетоды обнаружения кристаллов в суставах: status praesens. Часть 1Methods for detection of crystals in the joints: Status praesens. Part IKabalykM AKabalykM Amaxi_maxim@mail.ruДубиковА. И.DubikovA I-PetrikeyevaT YuPetrikeyevaT Yu-201215062012503№3 (2012)8791Copyright © Kabalyk M.A., Дубиков А.И., Petrikeyeva T.Y., 20122012Kabalyk M.A., Дубиков А.И., Petrikeyeva T.Y.Kabalyk M.A., Dubikov A.I., Petrikeyeva T.Y.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://rsp.mediar-press.net/rsp/article/view/852References<div><p>Yeo I.B. An address on the therapeutics of the uric acid diathesis. Br Med J 1888; 1(1410):16-9.</p><p>Phelps P., Steele A.D., McCarty D.J. Jr. Compensated polarized light microscopy. Identification of crystals in synovial fluids from gout and pseudogout. JAMA 1968;203(7):508-12.</p><p>Zhang W., Doherty M., Bardin T. et al. European League Against Rheumatism recommendations for calcium pyrophosphate deposition. Part I: terminology and diagnosis. Ann Rheum Dis 2011;70:563-70.</p><p>Zhang W., Doherty M., Pascual E. et al. EULAR recommendations for calcium pyrophosphate deposition. Part II: Management. Ann Rheum Dis 2011;70:571-5.</p><p>McCarty D.J., Kohn N.N., Faires J.S. The significance of calcium phosphate crystals in the synovial fluid of arthritic patients: the «pseudogout syndrome». II. Identification of crystals. Ann Intern Med 1962;56:711-37.</p><p>Насонов Е.Л. Ревматология. Клинические рекомендации. М.: ГЭОТАР-Медиа, 2008;99-110.</p><p>Барскова В.Г. Рекомендации Европейской антиревматической лиги по терминологии и диагностике болезни депонирования кристаллов пирофосфата кальция: комментарии эксперта. Совр ревматол 2011;2:6-8.</p><p>Барскова В.Г. Перспективы улучшения диагностики и лечения микрокристаллических артритов (интервью). Совр ревматол 2011;1:86-8.</p><p>McCarty D.J., Hollander J.L. Identification of urate crystals in gouty synovial fluid. Ann Intern Med 1961;54:452-60.</p><p>Vernon Roberts B. Synovial fluid and its examination. In: Scott J.T., ed. Copeman's textbook of the rheumatic diseases. 6th ed. Edinburgh: Churchill Livingstone, 1986;251-77.</p><p>Hearn P.R., Guilland-Cumming D.F., Russell G.G. Pathogenesis of chondrocalcinosis and pseudogout. Metabolism of inorganic pyrophosphate and production of calcium pyrophosphate dihydrate crystals. Ann Rheum Dis 1983;42:107-8.</p><p>Schumacher H.R., Sieck M.S., Rothfuss C. et al. Reproducibility of synovial fluid analyses. A study among four laboratories. Arthr Rheum 1986;29:770-4.</p><p>McGill N.W., York H. Reproducibility of synovial fluid examination for crystals. Aust NZ J Med 1991;34:710-3.</p><p>Hasselbacher P. Variation in synovial fluid analysis by hospital laboratories. Arthr Rheum 1987;30:637-42.</p><p>Pascual E., Jovani V. Synovial fluid analysis. Best Pract Res Clin Rheumatol 2005;19:371-86.</p><p>Yavorskyy A., Hernandez-Santana A., McCarthy G. et al. Detection of calcium phosphate crystals in the joint fluid of patients with osteoarthritis - analytical approaches and challenges. Analyst 2008;133(3):302-18.</p><p>Ivorra J., Rosas J., Pascual E. Most calcium pyrophosphate crystals appear as non-birefringent. Ann Rheum Dis 1999;58:582-4.</p><p>McCarthy G.M. Crystal deposition diseases: out of sight, out of mind. Curr Opin Rheumatol 2005;17:312-3.</p><p>Lumbreras B., Pascual E., Frasquet J. et al. Analysis for crystals in synovial fluid: training of the analysts results in high consistency. Ann Rheum Dis 2005;64:612-5.</p><p>Paul H., Reginato A.J., Schumacher R. Alizarin red S staining as a screening test to detect calcium compounds in synovial fluid. Arthr Rheum 1983;26:191-200.</p><p>Eggelmeijer F., Dijkmans B.A., Macfarlane J.D. et al. Alizarin red S staining of synovial fluid in inflammatory joint disorders. Clin Exp Rheumatol 1991;9:11-6.</p><p>Huang J.W., Chen W.J., Liao S.K. et al. Osteoblastic differentiation of rabbit mesenchymal stem cells loaded in A carrier system of Pluronic F127 and Interpore. Chang Gung Med J 2006;29:363-72.</p><p>Ortiz-Bravo E. The test of the synovial fluid in microcrystalline joint diseases. Rev Prat 1994;44:174-7.</p><p>Shoji K. Alizarin red S staining of calcium compound crystals in synovial fluid. Nippon Seikeigeka Gakkai Zasshi 1993;67:201-10.</p><p>Lazcano O., Li C., Pierre R.V. et al. Clinical utility of the alizarin red S stain on permanent preparations to detect calcium-containing compounds in synovial fluid. Am J Clin Pathol 1993;99:90-6.</p><p>Wheeler A.P., Graham B.S. Pseudogout presenting with low synovial fluid glucose: identification of crystals by gram stain. Am J Med Sci 1985;289(2):68-9.</p><p>Petrocelli A., Wong A.L., Swezy L. Identification of pathologic synovial fluid crystals on Gram stains. J Clin Rheumatol 1998;4:103-5.</p><p>Bills C.E., Eisenberg H., Pallante S.L. Complexes of organic acids with calcium phosphate: the von Kossa stain as a clue to the composition of bone mineral. Johns Hopkins Med J 1997;128(4):194-207.</p><p>Krutsay M. Methods for demonstration of some calcium compounds in histological sections. Acta Histochem 1963;15:189-91.</p><p>Raustyte G., Caye-Thomasen P., Hermansson A. et al. Calcium deposition and expression of bone modelling markers in the tympanic membrane following acute otitis media. Int J Pediatr Otorhinolaryngol 2006;70:529-39.</p><p>Bills C.E., Eisenberg H., Pallante S.L. Complexes of organic acids with calcium phosphate: the Von Kossa stain as a clue to the composition of bone mineral. Johns Hopkins Med J 1974;128:194-207.</p><p>Asselman M., Verhulst A., de Broe M.E. et al. Calcium oxalate crystal adherence to hyaluronan-, osteopontin-, and CD44-expressing injured/regenerating tubular epithelial cells in rat kidneys. J Am Soc Nephrol 2003;14:3155-66.</p><p>Bonewald F., Harris S.E., Rosser J. et al. Calcif. von Kossa staining alone is not sufficient to confirm that mineralization in vitro represents bone formation. Tissue Int 2003;72(5):537-47.</p><p>Henry M.J., Burton L.G., Stanley M.W. et al. Application of a modified Diff-Quik stain to fine needle aspiration smears: rapid staining with improved cytologic detail. Acta Cytol 1987;31(6):954-5.</p><p>Selvi E., Manganelli S., Catenaccio M. et al. Diff Quik staining method for detection and identification of monosodium urate and calcium pyrophosphate crystals in synovial fluids. Ann Rheum Dis 2001;60:194-8.</p><p>Huang Y.X. Effects of prolonged kanamycin administration on cochlear anatomy and auditory brainstem response thresholds in chickens. Curr Appl Phys 2005;5:553-6.</p><p>Freudiger C.W., Min W., Saar B.G. et al. Label-free biomedical imaging with high sensitivity by stimulated Raman scattering microscopy. Science 2008;322(5909):1857-61.</p><p>Zha Z.G., Yao C.C., Tu M. et al. Correlation of the size and shape of the solid particles in synovial fluid and knee joint disease. Curr Appl Phys 2007;7(S1):112-5.</p><p>Gardner D.L., McGovern Salter D., Oates K. SEM microscopy. Microsc Res Technol 1997;37:245-70.</p><p>Fuerst M., Bertrand J., Lammers L. et al. Calcification of articular cartilage in human osteoarthritis. Arthr Rheum 2009;60(9):694-703.</p><p>Hayes A., Turner I.G., Powell K.A. et al. Osteoarthritis. J Mater Sci Mater Med 1992;3:75-8.</p><p>Moradi-Bidhendi N., Turner I.G. Bidirectional regulation of osteoclast function by nitric oxide synthase isoforms. J Mater Sci Mater Med 1995;6:51-5.</p><p>Doyle D.V., Dieppe P.A., Crocker P.R. et al. Mixed crystal deposition in an osteoarthritic joint. J Pathol 1977;123(1):1-4.</p><p>Cunningham T., Uebelthart D., Very J.M. et al. Synovial fluid hydroxyapatite crystals: detection thresholds of two methods. Ann Rheum Dis 1989;48:829-31.</p><p>Li-Yu J., Clayburne G.M., Sieck M.S. et al. Calcium apatite crystals in synovial fluid rice bodies. Ann Rheum Dis 2002;61:387-90.</p><p>Ali S.Y. Apatite-type crystal deposition in arthritic cartilage. Scan Electron Microsc 1985;4:1555-66.</p><p>Ali S.Y., Gray J.C., Wisby A. et al. Preparation of thin cryo-sections for electron probe analysis of calcifying cartilage. J Microsc 1977;111(1):65-76.</p><p>Lee R.S., Kayser M.V., Ali S.Y. Calcium phosphate microcrystal deposition in the human intervertebral disc. J Anat 2006;208:13-9.</p><p>Pascual E., Jovani V. Synovial fluid analysis. Best Pract Res Clin Rheumatol 2005;19:371-86.</p><p>Arsenault A.L., Hunziker E.B. Electron microscopic analysis of mineral deposits in the calcifying epiphyseal growth plate. Calcif Tissue Int 1988;42(2):119-26.</p><p>Bardin T., Schumacher H.R., Lansaman J. et al. Transmission electron microscopic identification of silicon-containing particles in synovial fluid: potential confusion with calcium pyrophosphate dihydrate and apatite crystals. Ann Rheum Dis 1984;43:624-7.</p><p>Bonavita J.A., Dalinka M.K., Schumacher H.R. Hydroxyapatite deposition disease. Radiology 1980;134:621-5.</p><p>Suvorova E.I., Buffat P.A. Electron diffraction and high resolution transmission electron microscopy in the characterization of calcium phosphate precipitation from aqueous solutions under biomineralization conditions. Eur Cells Mater 2001;1:27-42.</p><p>Nero P., Nogueira I., Vilar R. et al. Synovial fluid crystal identification by electron microscopy. Acta Reumatol Port 2006;31:75-81.</p><p>Smith D.A., Connell S.D., Robinson C. et al. Analysis biological fluid by spectoscpy. Anal Chim Acta 2003;479:39-57.</p></div><br /><div><p>Yeo I.B. An address on the therapeutics of the uric acid diathesis. Br Med J 1888; 1(1410):16-9.</p><p>Phelps P., Steele A.D., McCarty D.J. Jr. Compensated polarized light microscopy. Identification of crystals in synovial fluids from gout and pseudogout. JAMA 1968;203(7):508-12.</p><p>Zhang W., Doherty M., Bardin T. et al. European League Against Rheumatism recommendations for calcium pyrophosphate deposition. Part I: terminology and diagnosis. Ann Rheum Dis 2011;70:563-70.</p><p>Zhang W., Doherty M., Pascual E. et al. EULAR recommendations for calcium pyrophosphate deposition. Part II: Management. Ann Rheum Dis 2011;70:571-5.</p><p>McCarty D.J., Kohn N.N., Faires J.S. The significance of calcium phosphate crystals in the synovial fluid of arthritic patients: the «pseudogout syndrome». II. Identification of crystals. Ann Intern Med 1962;56:711-37.</p><p>Насонов Е.Л. Ревматология. Клинические рекомендации. М.: ГЭОТАР-Медиа, 2008;99-110.</p><p>Барскова В.Г. Рекомендации Европейской антиревматической лиги по терминологии и диагностике болезни депонирования кристаллов пирофосфата кальция: комментарии эксперта. Совр ревматол 2011;2:6-8.</p><p>Барскова В.Г. Перспективы улучшения диагностики и лечения микрокристаллических артритов (интервью). Совр ревматол 2011;1:86-8.</p><p>McCarty D.J., Hollander J.L. Identification of urate crystals in gouty synovial fluid. Ann Intern Med 1961;54:452-60.</p><p>Vernon Roberts B. Synovial fluid and its examination. In: Scott J.T., ed. Copeman's textbook of the rheumatic diseases. 6th ed. Edinburgh: Churchill Livingstone, 1986;251-77.</p><p>Hearn P.R., Guilland-Cumming D.F., Russell G.G. Pathogenesis of chondrocalcinosis and pseudogout. Metabolism of inorganic pyrophosphate and production of calcium pyrophosphate dihydrate crystals. Ann Rheum Dis 1983;42:107-8.</p><p>Schumacher H.R., Sieck M.S., Rothfuss C. et al. Reproducibility of synovial fluid analyses. A study among four laboratories. Arthr Rheum 1986;29:770-4.</p><p>McGill N.W., York H. Reproducibility of synovial fluid examination for crystals. Aust NZ J Med 1991;34:710-3.</p><p>Hasselbacher P. Variation in synovial fluid analysis by hospital laboratories. Arthr Rheum 1987;30:637-42.</p><p>Pascual E., Jovani V. Synovial fluid analysis. Best Pract Res Clin Rheumatol 2005;19:371-86.</p><p>Yavorskyy A., Hernandez-Santana A., McCarthy G. et al. Detection of calcium phosphate crystals in the joint fluid of patients with osteoarthritis - analytical approaches and challenges. Analyst 2008;133(3):302-18.</p><p>Ivorra J., Rosas J., Pascual E. Most calcium pyrophosphate crystals appear as non-birefringent. Ann Rheum Dis 1999;58:582-4.</p><p>McCarthy G.M. Crystal deposition diseases: out of sight, out of mind. Curr Opin Rheumatol 2005;17:312-3.</p><p>Lumbreras B., Pascual E., Frasquet J. et al. Analysis for crystals in synovial fluid: training of the analysts results in high consistency. Ann Rheum Dis 2005;64:612-5.</p><p>Paul H., Reginato A.J., Schumacher R. Alizarin red S staining as a screening test to detect calcium compounds in synovial fluid. Arthr Rheum 1983;26:191-200.</p><p>Eggelmeijer F., Dijkmans B.A., Macfarlane J.D. et al. Alizarin red S staining of synovial fluid in inflammatory joint disorders. Clin Exp Rheumatol 1991;9:11-6.</p><p>Huang J.W., Chen W.J., Liao S.K. et al. Osteoblastic differentiation of rabbit mesenchymal stem cells loaded in A carrier system of Pluronic F127 and Interpore. Chang Gung Med J 2006;29:363-72.</p><p>Ortiz-Bravo E. The test of the synovial fluid in microcrystalline joint diseases. Rev Prat 1994;44:174-7.</p><p>Shoji K. Alizarin red S staining of calcium compound crystals in synovial fluid. Nippon Seikeigeka Gakkai Zasshi 1993;67:201-10.</p><p>Lazcano O., Li C., Pierre R.V. et al. Clinical utility of the alizarin red S stain on permanent preparations to detect calcium-containing compounds in synovial fluid. Am J Clin Pathol 1993;99:90-6.</p><p>Wheeler A.P., Graham B.S. Pseudogout presenting with low synovial fluid glucose: identification of crystals by gram stain. Am J Med Sci 1985;289(2):68-9.</p><p>Petrocelli A., Wong A.L., Swezy L. Identification of pathologic synovial fluid crystals on Gram stains. J Clin Rheumatol 1998;4:103-5.</p><p>Bills C.E., Eisenberg H., Pallante S.L. Complexes of organic acids with calcium phosphate: the von Kossa stain as a clue to the composition of bone mineral. Johns Hopkins Med J 1997;128(4):194-207.</p><p>Krutsay M. Methods for demonstration of some calcium compounds in histological sections. Acta Histochem 1963;15:189-91.</p><p>Raustyte G., Caye-Thomasen P., Hermansson A. et al. Calcium deposition and expression of bone modelling markers in the tympanic membrane following acute otitis media. Int J Pediatr Otorhinolaryngol 2006;70:529-39.</p><p>Bills C.E., Eisenberg H., Pallante S.L. Complexes of organic acids with calcium phosphate: the Von Kossa stain as a clue to the composition of bone mineral. Johns Hopkins Med J 1974;128:194-207.</p><p>Asselman M., Verhulst A., de Broe M.E. et al. Calcium oxalate crystal adherence to hyaluronan-, osteopontin-, and CD44-expressing injured/regenerating tubular epithelial cells in rat kidneys. J Am Soc Nephrol 2003;14:3155-66.</p><p>Bonewald F., Harris S.E., Rosser J. et al. Calcif. von Kossa staining alone is not sufficient to confirm that mineralization in vitro represents bone formation. Tissue Int 2003;72(5):537-47.</p><p>Henry M.J., Burton L.G., Stanley M.W. et al. Application of a modified Diff-Quik stain to fine needle aspiration smears: rapid staining with improved cytologic detail. Acta Cytol 1987;31(6):954-5.</p><p>Selvi E., Manganelli S., Catenaccio M. et al. Diff Quik staining method for detection and identification of monosodium urate and calcium pyrophosphate crystals in synovial fluids. Ann Rheum Dis 2001;60:194-8.</p><p>Huang Y.X. Effects of prolonged kanamycin administration on cochlear anatomy and auditory brainstem response thresholds in chickens. Curr Appl Phys 2005;5:553-6.</p><p>Freudiger C.W., Min W., Saar B.G. et al. Label-free biomedical imaging with high sensitivity by stimulated Raman scattering microscopy. Science 2008;322(5909):1857-61.</p><p>Zha Z.G., Yao C.C., Tu M. et al. Correlation of the size and shape of the solid particles in synovial fluid and knee joint disease. Curr Appl Phys 2007;7(S1):112-5.</p><p>Gardner D.L., McGovern Salter D., Oates K. SEM microscopy. Microsc Res Technol 1997;37:245-70.</p><p>Fuerst M., Bertrand J., Lammers L. et al. Calcification of articular cartilage in human osteoarthritis. Arthr Rheum 2009;60(9):694-703.</p><p>Hayes A., Turner I.G., Powell K.A. et al. Osteoarthritis. J Mater Sci Mater Med 1992;3:75-8.</p><p>Moradi-Bidhendi N., Turner I.G. Bidirectional regulation of osteoclast function by nitric oxide synthase isoforms. J Mater Sci Mater Med 1995;6:51-5.</p><p>Doyle D.V., Dieppe P.A., Crocker P.R. et al. Mixed crystal deposition in an osteoarthritic joint. J Pathol 1977;123(1):1-4.</p><p>Cunningham T., Uebelthart D., Very J.M. et al. Synovial fluid hydroxyapatite crystals: detection thresholds of two methods. Ann Rheum Dis 1989;48:829-31.</p><p>Li-Yu J., Clayburne G.M., Sieck M.S. et al. Calcium apatite crystals in synovial fluid rice bodies. Ann Rheum Dis 2002;61:387-90.</p><p>Ali S.Y. Apatite-type crystal deposition in arthritic cartilage. Scan Electron Microsc 1985;4:1555-66.</p><p>Ali S.Y., Gray J.C., Wisby A. et al. Preparation of thin cryo-sections for electron probe analysis of calcifying cartilage. J Microsc 1977;111(1):65-76.</p><p>Lee R.S., Kayser M.V., Ali S.Y. Calcium phosphate microcrystal deposition in the human intervertebral disc. J Anat 2006;208:13-9.</p><p>Pascual E., Jovani V. Synovial fluid analysis. Best Pract Res Clin Rheumatol 2005;19:371-86.</p><p>Arsenault A.L., Hunziker E.B. Electron microscopic analysis of mineral deposits in the calcifying epiphyseal growth plate. Calcif Tissue Int 1988;42(2):119-26.</p><p>Bardin T., Schumacher H.R., Lansaman J. et al. Transmission electron microscopic identification of silicon-containing particles in synovial fluid: potential confusion with calcium pyrophosphate dihydrate and apatite crystals. Ann Rheum Dis 1984;43:624-7.</p><p>Bonavita J.A., Dalinka M.K., Schumacher H.R. Hydroxyapatite deposition disease. Radiology 1980;134:621-5.</p><p>Suvorova E.I., Buffat P.A. Electron diffraction and high resolution transmission electron microscopy in the characterization of calcium phosphate precipitation from aqueous solutions under biomineralization conditions. Eur Cells Mater 2001;1:27-42.</p><p>Nero P., Nogueira I., Vilar R. et al. Synovial fluid crystal identification by electron microscopy. Acta Reumatol Port 2006;31:75-81.</p><p>Smith D.A., Connell S.D., Robinson C. et al. Analysis biological fluid by spectoscpy. Anal Chim Acta 2003;479:39-57.</p></div><br />
The authors declare that there are no conflicts of interest present.